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Concurrent Hypertension and T2D Raises Risk for Mortality
Concurrent Hypertension and T2D Raises Risk for Mortality

Medscape

time2 days ago

  • Business
  • Medscape

Concurrent Hypertension and T2D Raises Risk for Mortality

The prevalence of concurrent hypertension and type 2 diabetes (T2D) doubled from approximately 6% to 12% in the United States between 1999 and 2018, with the coexistence of these conditions being associated with a notable increase in the risk for all-cause and cardiovascular mortality. METHODOLOGY: Hypertension and T2D are major contributors to morbidity and cardiovascular mortality, both in the United States and globally. Quantifying how each condition, alone or in combination, affects the risk for mortality is essential to guide interventions that reduce chronic disease burden and improve quality of life. Researchers analyzed data from 48,727 adults (mean age, 47.4 years; 51.8% women) in the 1999-2018 National Health and Nutrition Examination Survey to investigate the associations of concurrent hypertension and T2D with the risk for mortality. Participants were categorized into four groups: No hypertension and no T2D (50.5%), hypertension only (38.4%), T2D only (2.4%), and coexisting hypertension and T2D (8.7%); sociodemographic and clinical characteristic data were obtained through interview questionnaires. Participants were followed up for a median duration of 9.2 years, and the outcomes analyzed were all-cause and cardiovascular mortality. TAKEAWAY: During the follow-up period, 7734 deaths occurred, including 2013 cardiovascular deaths. Compared with having neither condition, having concurrent hypertension and T2D predicted a higher risk for both all-cause mortality (hazard ratio [HR], 2.46; 95% CI, 2.45-2.47) and cardiovascular mortality (HR, 2.97; 95% CI, 2.94-3.00), with stronger associations in women than in men ( P for interaction < .01). for interaction < .01). Compared with having hypertension or T2D only, having concurrent hypertension and T2D predicted an up to 66% higher risk for all-cause mortality and a more than twofold higher risk for cardiovascular mortality. Having concurrent prediabetes and elevated blood pressure was associated with an up to 19% higher risk for mortality than having neither condition or having just one of the conditions, indicating that the risk for mortality can begin increasing even before developing T2D or hypertension. IN PRACTICE: 'Given the growing aging population in the US and globally and the associated projected chronic disease burden, our findings underscore the critical need for public health policy and interventions that prevent and address multiple cardiometabolic morbidities to mitigate their downstream impact on further morbidity, extend the lifespan, and preserve quality of life,' the authors wrote. SOURCE: This study was led by Ye Yuan, Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York City. It was published online on May 21, 2025, in Diabetes Care . LIMITATIONS: This study was limited by the lack of longitudinal data on changes in hypertension and T2D status, control, and medication use throughout the follow-up period, hindering the ability to assess how these changes affected the risk for mortality over time. Additionally, the reliance on self-reported data for hypertension and T2D medication use, as well as other covariates such as alcohol use and smoking, may have introduced measurement error. DISCLOSURES: Some authors reported receiving grants from the National Heart, Lung, and Blood Institute; American Heart Association; National Institute on Minority Health and Health Disparities; and other sources. The authors reported having no conflicts of interest.

EXCLUSIVE How many days do YOU have left to live? Use Daily Mail's interactive tool to see if you'll make your next birthday
EXCLUSIVE How many days do YOU have left to live? Use Daily Mail's interactive tool to see if you'll make your next birthday

Daily Mail​

time3 days ago

  • General
  • Daily Mail​

EXCLUSIVE How many days do YOU have left to live? Use Daily Mail's interactive tool to see if you'll make your next birthday

A new interactive tool from the Daily Mail reveals how long you can expect to live based on your age in the US and UK. You can see what your chances are of dying before your next birthday, based on the latest official life expectancy data in both America and Britain. Your browser does not support iframes. Your browser does not support iframes. Your browser does not support iframes. Your browser does not support iframes.

Southeast Asia sees near 150% rise in heart disease, study shows
Southeast Asia sees near 150% rise in heart disease, study shows

Japan Times

time4 days ago

  • Business
  • Japan Times

Southeast Asia sees near 150% rise in heart disease, study shows

The number of people with cardiovascular disease surged by 148% in Southeast Asia over the past three decades, with the condition becoming the region's leading cause of mortality and morbidity, according to new research. A total 37 million people in the region suffered from cardiovascular disease in 2021 and 1.7 million died from it. The findings by researchers at Seattle-based Institute for Health Metrics and Evaluation and the National University of Singapore are based on analysis of health data between 1990 and 2021 from 10 Southeast Asian countries that make up the ASEAN bloc. The results, published this week in a special edition of The Lancet Public Health dedicated to the region, highlight the growing burden of public health, including cardiovascular disease, mental disorders, smoking and road injuries. The main reasons contributing to cardiovascular disease were high systolic blood pressure, dietary risks, air pollution, high low-density lipoprotein cholesterol, and tobacco use. The aging population in the region also contributes to the big jump in case numbers, according to Marie Ng, the lead author and affiliate associate professor at IHME and associate professor at NUS. "Without immediate action from each of the countries, these preventable health conditions will worsen causing more death and disability across ASEAN,' said Ng, who sought proper resource allocation from governments. It's worth noting that during the COVID-19 pandemic, the incidence of deaths due to cardiovascular disease rose more than predicted and a separate study from 2023 flagged the risk of increase in cardiovascular disease in children born to mothers infected with COVID-19 during pregnancy. The latest study published in The Lancet Public Health found that more than 80 million people in ASEAN suffered from major mental disorders, 70% higher than in 1990. A closer look by age showed 15- to 19-year-olds had the steepest climb in prevalence at nearly 11%.

Heart disease is Southeast Asia's biggest killer after 30-year surge, new research reveals
Heart disease is Southeast Asia's biggest killer after 30-year surge, new research reveals

South China Morning Post

time4 days ago

  • Business
  • South China Morning Post

Heart disease is Southeast Asia's biggest killer after 30-year surge, new research reveals

The number of people with cardiovascular disease surged by 148 per cent in Southeast Asia over the past three decades, with the condition becoming the region's leading cause of mortality and morbidity, according to new research. A total of 37 million people in the region suffered from cardiovascular disease in 2021 and 1.7 million died from it. The findings by researchers at Seattle-based Institute for Health Metrics and Evaluation and the National University of Singapore are based on analysis of health data between 1990 and 2021 from 10 Southeast Asian countries that make up the Asean bloc. The results, published this week in a special edition of The Lancet Public Health dedicated to the region, highlight the growing burden of public health, including cardiovascular disease, mental disorders, smoking and road injuries. The main reasons contributing to cardiovascular disease were high systolic blood pressure, dietary risks, air pollution, high low-density lipoprotein cholesterol, and tobacco use. Dietary risks and high systolic blood pressure are two of the main contributors to the region's heart disease epidemic. Photo: Shutterstock The ageing population in the region also contributes to the big jump in case numbers, according to Marie Ng, the lead author and affiliate associate professor at IHME and associate professor at NUS. 'Without immediate action from each of the countries, these preventable health conditions will worsen causing more death and disability across Asean,' said Ng, who sought proper resource allocation from governments. During the Covid-19 pandemic, the incidence of deaths due to cardiovascular disease rose more than predicted and a separate study from 2023 flagged the risk of increase in cardiovascular disease in children born to mothers infected with Covid during pregnancy. The latest study published in The Lancet Public Health found that more than 80 million people in Association of Southeast Asian Nations' member states suffered from major mental disorders, 70 per cent higher than in 1990. A closer look by age showed 15- to 19-year-olds had the steepest climb in prevalence at nearly 11 per cent.

Southeast Asia Sees Near 150% Rise in Heart Disease, Study Shows
Southeast Asia Sees Near 150% Rise in Heart Disease, Study Shows

Bloomberg

time4 days ago

  • Business
  • Bloomberg

Southeast Asia Sees Near 150% Rise in Heart Disease, Study Shows

The number of people with cardiovascular disease surged by 148% in Southeast Asia over the past three decades, with the condition becoming the region's leading cause of mortality and morbidity, according to new research. A total 37 million people in the region suffered from cardiovascular disease in 2021 and 1.7 million died from it. The findings by researchers at Seattle-based Institute for Health Metrics and Evaluation and the National University of Singapore are based on analysis of health data between 1990 and 2021 from 10 Southeast Asian countries that make up the Asean bloc.

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