Latest news with #precisionmatched
The Independent
24-07-2025
- Health
- The Independent
How do I donate blood? NHS call for donors with rare blood types
An initiative to help individuals with rare blood types secure a "precision-matched" donation to avoid the risk of severe reactions has been launched by the NHS. Scientists have embarked on a large-scale research project, DNA -testing the blood of 77,000 donors to date. Blood collected from these rare donors will be frozen, creating a vital reserve for others with the same specific blood type. Crucially, this stored blood will also be available to the donor themselves, should they ever require a transfusion. The reserve of rare blood donors will help avoid severe transfusion reactions, where the body sees the transfused blood as 'foreign' and rejects it. People who are particularly at risk of these reactions are those who regularly receive blood donations, including those with sickle cell disorder and thalassaemia. It comes after the NHS raised the alarm over low blood stocks last month. The NHS said it needed 200,000 more regular blood donors to sustain a safe and sufficient supply. Low blood stocks in 2024 prompted an "amber alert', but blood stocks have remained low ever since. NHS Blood and Transplant (NHSBT) is now urging more people to donate to avoid a "red alert", which is a critical situation where public safety is threatened. It described the past year as "challenging" for blood stocks, noting that just under 800,000 people are supporting the entire blood supply in England. How do I donate blood? The whole process of giving blood takes just one hour. When arriving at a blood donation centre, you are asked to complete a safety check to make sure you can give blood. You will be given 500ml of fluid to drink – drinking this will help the body maintain blood pressure, prevent dizziness and help the body replenish the donated blood. Then, to ensure it is safe to donate blood, medics will confirm your identity and information during a health check. In some cases, a registered nurse will follow it up. A drop of blood from your finger is then checked for iron levels. If these levels are too low, the appointment will be rescheduled. Those able to donate will be seated in the waiting area before being called to a donation chair. Here, a cuff will be placed on your arm to maintain a small amount of pressure during the donation before a suitable vein is found and the area is cleaned. Then, a needle will be inserted into your arm to collect your blood into a blood bag, which has your unique donor number on it. A scale weighs the blood and stops when you have donated 470ml - that's just under a pint. The needle is then removed from your arm, and a dressing is applied. The NHS says the process of giving blood should not hurt and should only take about 10 minutes. Who can donate blood? Although more donors are needed, some health, travel and lifestyle reasons may stop you from donating blood. Donors need to be fit and well, aged between 17 and 65, weigh between 7 stone 12 Ibs (50kg) and 25 stone (158kg) and have suitable veins. However, you can't donate blood if you have cancer, some heart conditions, have tested positive for HIV or are a hepatitis B or C carrier. If you have received blood platelets, plasma or any other blood products after January 1980, or if you have injected non-prescribed drugs including body-building and injectable tanning agents, you also cannot donate. If you've had anal sex with a new partner in the last three months, you may have to postpone your donation. If you feel unwell, are pregnant or have had a baby in the last six months, have had a tattoo or piercing, or have recently travelled to certain countries outside the UK, you may also have to wait before you can donate blood. Where can I donate blood? There are thousands of blood donation venues across England, some are permanent and others are pop-ups. Church halls, sports centres, mosques, football stadiums and hotels are all used as pop-up venues. To check where your closest one is, visit the Give Blood website. You will need to book an appointment ahead of your donation, which can be done online as soon as you have signed up as a blood donor. What type of blood is needed? There is a 'critical' need for more donors who have the so-called universal blood type, O negative blood, which is needed for treatment in emergencies. The NHS said there is also a need for more Black donors, who are more likely to have specific blood types which can help treat people with sickle cell disease.
The Independent
23-07-2025
- Health
- The Independent
NHS plan to achieve precision-matched blood transfusions
The NHS has launched a pioneering initiative to identify and secure blood donations from individuals with rare blood types, aiming to provide "precision-matched" transfusions. As part of this UK-first drive, scientists have DNA-tested the blood of 77,000 donors to date, with the goal of identifying hundreds more rare donors. Blood collected from these rare donors will be frozen to create a vital reserve, which will also be available to the donors themselves if they require a transfusion. This large-scale DNA testing helps to mitigate the risk of severe transfusion reactions, particularly for patients who regularly receive blood, such as those with sickle cell disorder and thalassaemia. NHS Blood and Transplant highlights the critical importance of precise blood matching due to the 362 known blood types, calling this project a significant step towards wider precision-matched blood use.
The Independent
23-07-2025
- Health
- The Independent
NHS on the hunt for ‘precision-matched' blood donors
The NHS is searching for blood donors with rare blood types so it can ensure patients in need can receive 'precision-matched' blood. Scientists have tested tens of thousands of blood donors to see if they have rare blood types in a UK-first. The blood from donors with rare blood types will be collected and frozen so it can be used to help other people with the same type of blood. It will also be available should the donor be in a situation where they themselves need a blood transfusion. The new drive to find precision-matched blood donors comes to help people who are at risk of blood transfusion side effects. NHS Blood and Transplant (NHSBT) said that blood matching is 'vital' due to the complexity of blood groups – there are 362 known blood types. So far its scientists have DNA-tested the blood types of 77,000 donors as part of a research project. This is the first time that blood types have been DNA tested in the UK at-scale, NHSBT said. Dozens of rare blood donors have been identified during the process and it is hoped the number will rise to hundreds. This means that blood from these donors can be used as 'personalised, precision-matched transfusion' for those in need. This can help avoid severe transfusion reactions – where the body sees the transfused blood as 'foreign' and rejects it. People who are particularly at risk of these reactions are those who regularly receive blood donations including those with sickle cell disorder and thalassaemia. Experts hailed the project as the 'first major step' towards rolling out precision-matched blood more widely. Dr Gail Miflin, chief medical officer at NHSBT, said: 'Taking these 77,000 donors and testing their blood to such a precise level has been an incredible undertaking and will work to significantly change the way we issue blood – especially to those patients at higher risk of transfusion related reactions. 'We will be able to match to an increasing number of blood groups, ensuring that patients have blood that is most similar to their own and reducing the risk of any reactions. It is an example of just how we are driving innovation which can radically improve patient outcomes.' NHSBT's genomics programme director, Kate Downes, added: 'This inventory of blood will enhance our capacity to find units with rare blood groups for difficult to match patients as well as provide better matched units for patients who have an increased risk of transfusion reactions, aiding us in our mission to save and improve even more lives. 'This genotyping is a first major step towards rolling out precision matched blood more widely, which would be a landmark change in how blood is matched.'
The Independent
23-07-2025
- Health
- The Independent
NHS launches major search for donors with rare blood types
The NHS has launched a pioneering initiative to identify and secure blood donations from individuals with rare blood types, ensuring patients receive "precision-matched" transfusions. This UK-first drive aims to mitigate the risk of adverse reactions for those requiring blood. Scientists have embarked on a large-scale research project, DNA -testing the blood of 77,000 donors to date. Blood collected from these rare donors will be frozen, creating a vital reserve for others with the same specific blood type. Crucially, this stored blood will also be available to the donor themselves, should they ever require a transfusion. NHS Blood and Transplant (NHSBT) underscores the critical importance of precise blood matching, citing the intricate nature of blood groups, with 362 known types. The organisation stated that blood matching is "vital" given this complexity, highlighting the necessity of this new approach to enhance patient safety. This is the first time that blood types have been DNA tested in the UK at-scale, NHSBT said. Dozens of rare blood donors have been identified during the process and it is hoped the number will rise to hundreds. This means that blood from these donors can be used as 'personalised, precision-matched transfusion' for those in need. This can help avoid severe transfusion reactions – where the body sees the transfused blood as 'foreign' and rejects it. People who are particularly at risk of these reactions are those who regularly receive blood donations including those with sickle cell disorder and thalassaemia. Experts hailed the project as the 'first major step' towards rolling out precision-matched blood more widely. Dr Gail Miflin, chief medical officer at NHSBT, said: 'Taking these 77,000 donors and testing their blood to such a precise level has been an incredible undertaking and will work to significantly change the way we issue blood – especially to those patients at higher risk of transfusion-related reactions. 'We will be able to match to an increasing number of blood groups, ensuring that patients have blood that is most similar to their own and reducing the risk of any reactions. 'It is an example of just how we are driving innovation which can radically improve patient outcomes.' NHSBT's genomics programme director, Kate Downes, added: 'This inventory of blood will enhance our capacity to find units with rare blood groups for difficult to match patients as well as provide better matched units for patients who have an increased risk of transfusion reactions, aiding us in our mission to save and improve even more lives. 'This genotyping is a first major step towards rolling out precision-matched blood more widely, which would be a landmark change in how blood is matched.'
Yahoo
22-07-2025
- Health
- Yahoo
NHS on the hunt for ‘precision-matched' blood donors
The NHS is searching for blood donors with rare blood types so it can ensure patients in need can receive 'precision-matched' blood. Scientists have tested tens of thousands of blood donors to see if they have rare blood types in a UK-first. The blood from donors with rare blood types will be collected and frozen so it can be used to help other people with the same type of blood. It will also be available should the donor be in a situation where they themselves need a blood transfusion. The new drive to find precision-matched blood donors comes to help people who are at risk of blood transfusion side effects. NHS Blood and Transplant (NHSBT) said that blood matching is 'vital' due to the complexity of blood groups – there are 362 known blood types. So far its scientists have DNA-tested the blood types of 77,000 donors as part of a research project. This is the first time that blood types have been DNA tested in the UK at-scale, NHSBT said. Dozens of rare blood donors have been identified during the process and it is hoped the number will rise to hundreds. This means that blood from these donors can be used as 'personalised, precision-matched transfusion' for those in need. This can help avoid severe transfusion reactions – where the body sees the transfused blood as 'foreign' and rejects it. People who are particularly at risk of these reactions are those who regularly receive blood donations including those with sickle cell disorder and thalassaemia. Experts hailed the project as the 'first major step' towards rolling out precision-matched blood more widely. Dr Gail Miflin, chief medical officer at NHSBT, said: 'Taking these 77,000 donors and testing their blood to such a precise level has been an incredible undertaking and will work to significantly change the way we issue blood – especially to those patients at higher risk of transfusion related reactions. 'We will be able to match to an increasing number of blood groups, ensuring that patients have blood that is most similar to their own and reducing the risk of any reactions. It is an example of just how we are driving innovation which can radically improve patient outcomes.' NHSBT's genomics programme director, Kate Downes, added: 'This inventory of blood will enhance our capacity to find units with rare blood groups for difficult to match patients as well as provide better matched units for patients who have an increased risk of transfusion reactions, aiding us in our mission to save and improve even more lives. 'This genotyping is a first major step towards rolling out precision matched blood more widely, which would be a landmark change in how blood is matched.'
