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The 2025 Men's Health Ultimate Supplement Guide

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." ELSEWHERE ON THE internet, you're going to see a whole lot of nonsense about supplements. You might hear—either from so-called 'experts' or from supplement companies themselves—that certain pills or powders can help prevent and treat disease. You might read that supplements can dramatically change how you look and feel. You might even witness that certain products have the ability to detox your body from harmful environmental toxins. If all of this sounds too good to be true, that's because it largely is. We know this because for close to four decades, Men's Health has tracked the scientific research and spoken with trusted authorities in the dietary supplement space. We've taken all that scientific research and those conversations with credentialed experts and built the ultimate guide to supplement buying. Shop Now In this definitive Men's Health guide you'll find: How to ensure you're buying a safe and effective supplement, whichever supplement you're looking to buy An in-depth look into muscle-building supplements, including protein powder, creatine, and pre-workout An analysis of gut health supplements, which covers prebiotics and probiotics Recommendations on immunity, disease prevention, and brain health supplements Plus: A reference chart for tons of additional supplements that gives our assessment on which of the claims are backed by science—and which aren't. In short, if you've ever had a question about a supplement, you're almost guaranteed you'll find an answer to it in this guide. Without this information, know that there's one big thing you should watch out for: lack of oversight. Supplement manufacturers can get away with making claims about what's in their products and what they can do for you, health-wise, because they don't have provide evidence to any governing body. In the United States, the FDA can ban ingredients, issue recalls for supplements already on the market, and send warning letters to supplement companies, but the agency largely does not regulate supplements before they go on sale. That leaves you, as a consumer, to figure out if a product is safe and effective. And if that feels overwhelming, we got you. Join the Men's Health Community for Even More Perks MEN'S HEALTH MVP is a community of guys who are passionate about building their physical, mental, and emotional fitness, just as you are. And our MH MVP program is about giving you as many tools as possible to make that possible. This Hypertrophy program is just one of the vast array of features available that'll help you become your best self. Unlock all stories and curated training plans for all fitness goals, as well as cutting-edge reviews and in-depth breakdowns of new workout principles at Get every print issue delivered straight to your mailbox Receive a weekly members-only newsletter with deep insights from MH's fitness experts Access hundreds of streaming video workouts on demand Shop Now You Might Also Like The Best Hair Growth Shampoos for Men to Buy Now 25 Vegetables That Are Surprising Sources of Protein