Study reveals periods of significant weight regain after weight loss drugs
The research, a review of 11 clinical trials published in BMC Medicine, found a broad trend of weight rebound after medication courses concluded.
Significant periods of weight regain were observed at eight, 12, and 20 weeks after stopping the anti-obesity medications.
The analysis revealed that the weight rebound typically continued for an average of 20 weeks before stabilising.
Researchers suggest that factors such as the specific medication taken and the consistency of lifestyle changes influence the extent of weight regain, calling for further long-term studies.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
The Sun
an hour ago
- The Sun
I'm on Mounjaro & here's what happens after drinking on fat jabs – the hangxiety & acid reflux is the worst for starters
A WOMAN has revealed the awful side effects she has experienced when drinking on Mounjaro. Since becoming available on the NHS earlier this year, weight loss jab Mounjaro has helped thousands of Brits shed unwanted weight. 2 2 And whilst many are overjoyed with the results, some have reported major side effects, including burning skin and kidney problems. Jade, has been on Mounjaro since February, and has been documenting her journey on her TikTok account @ The busy mum has described the jabs as being "amazing"; however, she added that she has some nasty side effects when she drinks. "This is the reality of drinking on Mounjaro, she told her 12,000 TikTok followers. "I feel awful, emotionally, physically, in every way." Jade revealed that whilst she had actually been drinking she felt fine, however, the next day, she had the hangover from hell. Normally, when Jade drinks, she's either sick before she goes to bed, eats food, or drinks lots of water. Since she didn't do any of this on the night she was drinking, she is unsure whether this could have contributed to her awful hangover. Jade revealed that she was "out of the game" the day after she went out drinking, and still felt "emotionally unstable" two days after. She added that she hadn't even drunk loads, and hadn't felt this way for a long long time. I've lost nearly 6 stone in 9 months on fat jabs - trolls call me 'lazy' & say it's the 'easy way out' but I don't care "Honestly, just wanted to cry constantly for two days", she said. After doing some research, Jade discovered that when using Mounjaro, alchohol stays in your system longer, and your blood sugars are "all over the place." She added that she now gets awful acid reflux and "bad heartburn" for days after she drinks. Jade added that she experienced the "worst" hangxiety, and only felt "human" again four days after drinking. What to do if you lose too much weight too quickly whilst on Mounjaro IF you're losing too much weight too quickly while on Mounjaro, it's important to take action to avoid potential health risks like muscle loss, malnutrition, dehydration, and fatigue. Here's what you can do: Evaluate Your Caloric Intake Mounjaro reduces appetite, which can make it easy to eat too little. If you're losing weight too fast (more than two to three lbs per week after the initial adjustment period), try: Tracking your food intake to ensure you're eating enough calories (apps like MyFitnessPal can help). Increasing protein intake to preserve muscle mass (aim for 0.6–1g per pound of body weight). Adding healthy fats and complex carbs (e.g., avocados, nuts, whole grains) for balanced energy. Adjust Your Dosage (With Doctor's Approval) If your weight loss is too rapid or causing side effects, your doctor may: Pause dose increases or lower your dosage. Adjust your treatment plan to stabilise your weight loss. Strength Training & Exercise To prevent muscle loss: Incorporate resistance training at least two to three times per week. Stay active with low-impact exercises like walking or yoga. Hydrate & Manage Electrolytes Drink enough water (Mounjaro can reduce thirst). Electrolytes matter - Consider adding magnesium, sodium, and potassium if you feel weak or fatigued. Monitor for Malnutrition & Deficiencies Rapid weight loss can cause vitamin/mineral deficiencies (especially B12, iron, and electrolytes). If you experience: Fatigue, hair loss, or dizziness, ask your doctor about supplements. Consider Further Medical Guidance If your weight loss is excessive or causing health concerns, speak with your healthcare provider. They might adjust your dosage, diet, or exercise plan to help stabilise your weight loss. Addressing her followers, Jade asked if others had experienced the same thing, and whether she should give up drinking. Her video racked up over 224,000 views and was flooded with comments from people, many of whom had experienced the same thing. One person said: "I'm a good drinker but I had a glass and it knocked me for two days." A second person said: "I can't drink on it it makes me feel so sick." However, others reported that they felt fine after drinking, such as one person who said: "I can drink as normal." Another person said: "I feel fine the next day."
Telegraph
2 hours ago
- Telegraph
Third of young people want fat jabs as demand spirals
A third of young adults want to take fat jabs amid a surge in demand for the drugs, pharmacists have said. One in five people say they have tried to access a pharmacy weight-loss treatment in the past year but this figure is 35 per cent for those aged between 16 and 34. Pharmacists have raised the alarm that demand has far exceeded what can be clinically delivered. Concerns have also been raised that people could resort to looking for drugs such as Wegovy and Mounjaro from online sellers. Current guidelines state that patients being prescribed Mounjaro and Wegovy through pharmacies need a BMI of at least 35 and at least one weight-related comorbidity, such as diabetes, to be eligible. Wegovy can also be prescribed to patients with a BMI of 30–34 who meet the criteria for referral to specialist overweight and obesity management services. However, the NHS is only rolling out Mounjaro to patients with a BMI of over 40 and at least four co-morbidities. It spent £269million on fat jabs in 2024-2025 and prescriptions doubled to almost three million a year. Mounjaro, regarded as the strongest jab and known as King Kong, has driven the spike in prescriptions with 1.1million given out in a year compared with 3,300 in the previous 12 months. The National Pharmacy Association (NPA), which represents about 6,000 pharmacies, surveyed 2,000 Britons and found evidence of demand beyond what the NHS can offer. It is now seeking greater clarity on how pharmacies will be further involved in the distribution of weight-loss medication, something laid out in the Government's recent 10 Year Health Plan. Olivier Picard, chairman of the NPA, said: 'Weight-loss jabs are one of the biggest drug innovations this century but growing demand highlights the need to make sure this is appropriate for those who want it. 'It's clear from this polling that many more people are interested in getting weight-loss jabs than would actually be suitable for treatment. 'We want to make sure supplies are carefully managed so that those in most clinical need can benefit from medication. 'We're also urging the Government to bring forward plans to include pharmacies in the rollout of their NHS weight-management programme. 'Pharmacists are experts in medication and many have extensive experience delivering weight-loss injections as part of a package of care including lifestyle advice. 'Pharmacies are well placed to help roll this treatment out on the NHS and help people make the best use of these powerful medicines,' he added
Metro
3 hours ago
- Metro
GP reveals 5 common mistakes people make when stopping weight loss jabs
While treatments like Ozempic, Mounjaro and Wegovy can provide a helping hand, there's no magic bullet when it comes to losing weight. Given GLP-1 agonist medications have been shown to help people lose up to four times more than going it alone, it's no wonder they're popular. However, a proportion of the estimated 1.5 million people in the UK who are now on these jabs will struggle to keep the pounds off long-term — and some may even end up heavier than when they started. 'While it can differ depending on the individual, it's quite common for people to regain some of the weight lost once they stop taking the medication,' Dr Donald Grant, GP and senior clinical advisor at The Independent Pharmacy, tells Metro. There are a few factors behind this, from metabolism to appetite. But going back on your progress isn't inevitable, as long as you're careful to avoid these five common pitfalls. As these treatments work by suppressing appetite, Dr Grant warns that going cold turkey 'could increase it, leading to poor eating habits and potential weight gain.' If you're considering coming off your medication, he recommends speaking to your GP about doing so slowly and safely. 'A medical professional can advise further on a potential tapering plan, while also providing dietary advice and lifestyle habits that can help reduce weight gain,' he adds. According to a recent study of over 6,000 people by scientists at Oxford University, those who use GLP-1 drugs will put their weight back on within 10 months of stopping if they don't continue to maintain a healthy lifestyle. Dr Grant explains: 'When stopping weight loss injections, it's crucially important that individuals replace the treatment with another way to keep weight off.' Even 30 minutes of daily exercise can make all the difference, burning off some of those extra calories you're consuming and stopping you falling into a sedentary routine. Quick fixes and 'crash diets' rarely result in any lasting improvements — and the same is true for GLP-1 medications. 'Choosing to stop weight loss treatment too early is by far one of the most common errors people make,' says Dr Grant. 'These drugs are designed to be used long-term, but not doing so gives the body little time to adapt to the treatment.' It's a marathon, not a sprint, with many providers recommending a course of between 12 and 24 months. Unless you're prepared to make that commitment, you may not reap the full benefits of treatment. Making changes to your diet while taking Ozempic, Mounjaro or Wegovy is a vital step to maintaining your progress forward. In fact, Dr Grant claims failure to do so is a 'sure-fire way to regain weight lost'. 'It's important for people to draw up a dietary plan, including structured meal times to avoid overeating,' he explains. More Trending 'I also recommend a well-balanced diet including a variety of high-protein, fibre-rich and healthy fat foods.' 'While it's important not to create an unhealthy relationship with weight management, tracking weight closely once ending any treatments can help people adjust their routine to avoid losing progress,' says Dr Grant. It's easy to revert to old habits once you end a course of medication, but regular monitoring ensures you can get back on track before you lose too much progress. View More » Since you've put so much time, energy and potentially money into the progress you've made so far, just think of this as protecting your investment. Do you have a story to share? Get in touch by emailing MetroLifestyleTeam@ MORE: 'I've tried jabs and pills to lose weight – but my latest attempt is the most extreme' MORE: Lives at risk because we've already forgotten a basic mantra MORE: The golden rule for how long it should take you to pee Your free newsletter guide to the best London has on offer, from drinks deals to restaurant reviews.
