
US' DuPont launches AmberChrom TQ1 for biopharma applications
DuPont has expanded its bioprocessing portfolio with the launch of DuPont AmberChrom TQ1 chromatography resin for the purification of oligonucleotides and peptides in support of a wide-range of biopharma applications.
DuPont has launched AmberChrom TQ1 chromatography resin for purifying oligonucleotides and peptides, expanding its bioprocessing portfolio. The resin offers high capacity, throughput, and purity with low pressure, suitable for all scales. Internal studies using real-world drug feeds validated its performance across development stages.
'The introduction of DuPont AmberChrom TQ1 chromatography resin supports the accelerated development and commercialization of oligonucleotide and peptide therapeutics,' said Shane Kendra, Global Bioprocessing Market Leader for DuPont Water Solutions. 'In addition to expanding our capabilities, this new anion exchange chromatography resin offers exceptional performance, setting a new standard in this product class and creating new opportunities in high growth therapy areas.'
The new agarose-based chromatography resin offers increased loading capacity, higher throughput, and requires less pressure than comparable competing products within the same class. These characteristics make DuPont AmberChrom TQ1 chromatography resin an excellent choice for high resolution separations and polishing, offering high purity fractions in biomolecule purifications and the separation of closely-related impurities from target molecules. Its low-pressure build-up, combined with high-yield and purity for peptides and both DMT-Off and DMT-On oligonucleotides, makes the resin suitable for use in benchtop and large-scale commercial purifications.
To support the introduction of the resin, DuPont has published comprehensive internal application studies that used real-world drug feeds to validate performance characteristics; this documentation can also assist with the integration of the product into processes at every phase from drug discovery through commercialization.
'Further expansion of DuPont's bioprocessing portfolio reflects our commitment to providing a comprehensive one-stop shop for the purification and polishing of oligonucleotides and peptides,' said Kendra. 'Our technical teams and scientists are continually collaborating with customers to design efficient bioprocessing solutions for every stage of the drug development journey.'
DuPont AmberChrom TQ1 chromatography resin can be used in combination with existing AmberChrom XT and CG chromatography resins to purify various oligonucleotide feeds, or for the crude purification of peptide feeds in preparation for reverse phase chromatography.
DuPont introduced the new chromatography resin to the market during TIDES USA—a conference dedicated to accelerating oligonucleotide and peptide innovations. Hadi Fares, Ph.D, a bioprocessing application scientist with DuPont, presented application studies to demonstrate the performance capabilities of DuPont AmberChrom TQ1 chromatography resin, and how it complements existing resins within the DuPont bioprocessing portfolio.
On June 19, 2025, DuPont will host an educational webinar discussing the capabilities of DuPont AmberChrom TQ1 chromatography resin and how its loading capacity and purification efficacy can enhance purification of oligonucleotides and peptides.
As a global market leader in adsorbents and ion exchange resins with over 80 years of experience, DuPont bioprocessing solutions can accelerate and enhance the discovery and production of small molecule synthetics, oligonucleotides, and peptides, as well as diagnostics, by enabling complicated separations that help companies achieve their vision to manage and treat diseases. Note: The headline, insights, and image of this press release may have been refined by the Fibre2Fashion staff; the rest of the content remains unchanged.
Fibre2Fashion News Desk (HU)
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Fibre2Fashion
28-05-2025
- Fibre2Fashion
US' DuPont launches AmberChrom TQ1 for biopharma applications
DuPont has expanded its bioprocessing portfolio with the launch of DuPont AmberChrom TQ1 chromatography resin for the purification of oligonucleotides and peptides in support of a wide-range of biopharma applications. DuPont has launched AmberChrom TQ1 chromatography resin for purifying oligonucleotides and peptides, expanding its bioprocessing portfolio. The resin offers high capacity, throughput, and purity with low pressure, suitable for all scales. Internal studies using real-world drug feeds validated its performance across development stages. 'The introduction of DuPont AmberChrom TQ1 chromatography resin supports the accelerated development and commercialization of oligonucleotide and peptide therapeutics,' said Shane Kendra, Global Bioprocessing Market Leader for DuPont Water Solutions. 'In addition to expanding our capabilities, this new anion exchange chromatography resin offers exceptional performance, setting a new standard in this product class and creating new opportunities in high growth therapy areas.' The new agarose-based chromatography resin offers increased loading capacity, higher throughput, and requires less pressure than comparable competing products within the same class. These characteristics make DuPont AmberChrom TQ1 chromatography resin an excellent choice for high resolution separations and polishing, offering high purity fractions in biomolecule purifications and the separation of closely-related impurities from target molecules. Its low-pressure build-up, combined with high-yield and purity for peptides and both DMT-Off and DMT-On oligonucleotides, makes the resin suitable for use in benchtop and large-scale commercial purifications. To support the introduction of the resin, DuPont has published comprehensive internal application studies that used real-world drug feeds to validate performance characteristics; this documentation can also assist with the integration of the product into processes at every phase from drug discovery through commercialization. 'Further expansion of DuPont's bioprocessing portfolio reflects our commitment to providing a comprehensive one-stop shop for the purification and polishing of oligonucleotides and peptides,' said Kendra. 'Our technical teams and scientists are continually collaborating with customers to design efficient bioprocessing solutions for every stage of the drug development journey.' DuPont AmberChrom TQ1 chromatography resin can be used in combination with existing AmberChrom XT and CG chromatography resins to purify various oligonucleotide feeds, or for the crude purification of peptide feeds in preparation for reverse phase chromatography. DuPont introduced the new chromatography resin to the market during TIDES USA—a conference dedicated to accelerating oligonucleotide and peptide innovations. Hadi Fares, Ph.D, a bioprocessing application scientist with DuPont, presented application studies to demonstrate the performance capabilities of DuPont AmberChrom TQ1 chromatography resin, and how it complements existing resins within the DuPont bioprocessing portfolio. On June 19, 2025, DuPont will host an educational webinar discussing the capabilities of DuPont AmberChrom TQ1 chromatography resin and how its loading capacity and purification efficacy can enhance purification of oligonucleotides and peptides. As a global market leader in adsorbents and ion exchange resins with over 80 years of experience, DuPont bioprocessing solutions can accelerate and enhance the discovery and production of small molecule synthetics, oligonucleotides, and peptides, as well as diagnostics, by enabling complicated separations that help companies achieve their vision to manage and treat diseases. Note: The headline, insights, and image of this press release may have been refined by the Fibre2Fashion staff; the rest of the content remains unchanged. Fibre2Fashion News Desk (HU)


Time of India
23-05-2025
- Time of India
Farmer discovers 150 tonnes of gold worth over ₹340 crore on his land. The amount he will receive may surprise you
In what could have been a real-life rags-to-riches fairy tale, a French farmer has uncovered a hidden treasure beneath his land—only to be told he can't keep a single cent. The discovery? A staggering $4 billion worth of gold. The twist? A maze of legal and environmental restrictions that have turned Michel Dupont's golden dream into a bureaucratic nightmare. The Sparkle That Changed Everything Michel Dupont, a 52-year-old farmer from France's serene Auvergne region, was on what he called a routine check of his land when he noticed something unusual glinting under a muddy stream. Curious, he dug a little deeper. What he pulled from the earth changed his life—if not his fortune. 'I couldn't believe what I was holding in my hands,' Dupont recalled. What began as a single gold fragment quickly led to the discovery of more and more, until experts estimated that his land held up to 150 tonnes of gold—an amount valued at over $4 billion. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like If you eat ginger every day for a month, your body will experience the following phenomena Tips and Tricks Undo — Ignite_83 (@Ignite_83) A Law as Cold as the Metal It Guards But just as Dupont's heart soared, the crushing weight of legal red tape came crashing down. Despite the treasure lying beneath his own soil, the French government was quick to intervene. Authorities from the Auvergne region declared that any form of extraction would require strict environmental and technical assessments. Until then, Michel is legally barred from mining even a gram of the gold buried beneath his feet. Environmental regulations in France place heavy restrictions on activities that could disrupt ecologically sensitive or culturally significant regions—categories under which Dupont's farmland now unexpectedly falls. The irony is cruel: the very land that provided his livelihood has now become the reason he may never see a cent of his newfound wealth. You Might Also Like: Have scientists just found a new cosmic source of gold? How 'starquakes' might forge the glittering metal Gold vs. Green: The Backlash Begins The discovery has stirred unrest beyond the bureaucratic circles. Environmental activists have voiced strong objections to any proposed mining operations on Dupont's property, warning that the ecological damage and noise pollution would destroy the region's natural tranquility. 'I understand their caution,' Dupont admitted, though his voice carried the unmistakable weight of disappointment. 'It's frustrating to know what's there and be told you can't touch it. But I also love this land—I've worked it all my life. I want to do the right thing.' — MrBeats61134631 (@MrBeats61134631) From Farmer to Billionaire… to Bystander? Dupont's story is more than just one man's unlucky strike of fortune. It raises uncomfortable questions about land ownership, natural resource rights, and how far governments should go to protect the environment—even at the cost of an individual's golden opportunity. As the battle between regulation and riches unfolds, Michel Dupont stands at the crossroads—his boots firmly planted in fields worth billions, his hands empty. For now, the gold stays buried, and so too does the dream. You Might Also Like: People made money in gold, stocks and real estate. Then, why you could not? Akshat Shrivastava has an answer


Time of India
18-05-2025
- Time of India
The US towns that took on 'forever chemical' giants
WASHINGTON: No corner of Earth is untouched. From Tibet to Antarctica, so-called " " have seeped into the blood of nearly every living creature. Tainting food, water and wildlife, these toxic substances have been linked to ailments ranging from birth defects to rare cancers. Tired of too many ads? go ad free now Yet if it weren't for the efforts of residents in two heavily impacted American towns, the world might still be in the dark. In the new book "They Poisoned the World: Life and Death in the Age of Chemicals," investigative journalist Mariah Blake recounts how people in , West Virginia, and , New York, blew the whistle on the industrial giants that poisoned them -- and, in the process, forced the world to reckon with per‑ and polyfluoroalkyl substances, or . "We're talking about a class of chemicals that doesn't break down in the environment," Blake tells AFP, calling it the "worst contamination crisis in human history." First developed in the 1930s, PFAS are prized for their strength, heat resistance, and water- and grease-repelling powers. Built on the carbon-fluoride bond -- the strongest in chemistry -- they persist like radioactive waste and accumulate in our bodies, hence the "forever" nickname. Blake's research traces their history, from accidental discovery by a chemist to modern usage in cookware, clothing, and cosmetics. They might have remained a curiosity if Manhattan Project scientists hadn't needed a coating that could withstand atomic-bomb chemistry, helping companies produce them at scale. Corporate malfeasance Industry knew the risks early. Internal tests showed plant workers suffered chemical burns and respiratory distress. Tired of too many ads? go ad free now Crops withered and livestock died near manufacturing sites. So how did they get away with it? Blake tracks the roots to the 1920s, when reports emerged that leaded gasoline caused psychosis and death among factory workers. In response, an industry-backed scientist advanced a now-infamous doctrine: chemicals should be presumed safe until proven harmful. This "Kehoe principle" incentivized corporations to manufacture doubt around health risks -- a big reason it took until last year for the US to finalize a ban on asbestos. DuPont's own studies warned that Teflon had no place on cookware. But after a French engineer coated his wife's muffin tins with it, a Parisian craze took off -- and an American entrepreneur sold the idea back to DuPont. Soon nonstick pans were flying off shelves, thanks in part to a regulatory gap: PFAS, along with thousands of other chemicals, were "grandfathered" into the 1976 Toxic Substances Control Act and required no further testing. Massive litigation The cover-up began to unravel in the 1990s in Parkersburg, where DuPont had for decades been dumping Teflon waste into pits and the Ohio River. The town reaped economic benefits, but female plant workers were having babies with birth defects, a cattle farmer downstream was losing his herd, and residents developed rare cancers. Blake tells the story through "accidental activists." One is Michael Hickey, a preppy insurance underwriter with no interest in politics or the environment. After cancer took his father and friends, he started testing Hoosick Falls's water. Another is Emily Marpe, "a teen mom with a high school education" who saved to buy her family's dream house in upstate New York, only to learn the water flowing from the taps was fouled with PFAS that now coursed through their blood in massive levels. "She knew the science inside out," says Blake, "and became an incredibly articulate advocate." Years of litigation yielded hundreds of millions in settlements and forced DuPont and 3M to phase out two notorious PFAS. But the companies pivoted to substitutes like GenX -- later shown to be just as toxic. Still, Blake argues the tide is turning. France has banned PFAS in many consumer goods, the EU is considering a ban, and in the US, states are moving to restrict PFAS in sludge fertilizer and food packaging. Liabilities linked to the chemicals are driving major retailers from McDonald's to REI to pledge PFAS-free products. Her optimism is tempered by the political climate. Just this week, the Trump administration announced the rollback of federal drinking water standards for four next-generation PFAS chemicals. But she believes the momentum is real. "Ordinary citizens who set out to protect their families and communities have really created this dramatic change," she says. "It's like climate change -- it feels intractable, but here's a case where people have made major headway."