Sree Chitra completes six new tech transfers
Thiruvananthapuram: The Sree Chitra Tirunal Institute for Medical Sciences (SCTIMST), which has a long history of technology transfers and commercialisation of medical devices and biomaterials, made six new technological transfers, including a deep brain stimulator.
The indigenous development of a deep brain stimulator is for managing movement disorders such as Parkinson's disease and dystonia. The project was initiated with support from the technical research centre of the department of science and technology, Govt of India.
Another technology transfer made is the "mice transfer and enrichment box-tunnel system with securing gates." Laboratory mice constitute over 87% of the total laboratory animals used in research.
The test results using this system show that it can not only reduce stress during handling and cage shifting of animals but also act as an enrichment material inside the cage to reduce fighting behaviour and other unwanted behaviour observed in laboratory mice.
The "plasma proteins fibrinogen, thrombin albumin and IVIG" technology is a small-scale fractionation of plasma to obtain four plasma proteins: Fibrinogen, Thrombin, Albumin, and Immunoglobulin.
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Fibrinogen concentrate and thrombin are two major proteins of blood plasma. It has enormous potential in the preparation of wound healing matrices, tissue adhesives, and haemostats. Albumin is used as a replacement therapy in cases where blood volume loss occurs, liver diseases, and cancer.
Two main uses for IVIG are as replacement therapy in primary or acquired antibody deficiency disorders and as immunomodulatory agents in patients with autoimmune or inflammatory conditions, and it has enormous potential.
The "intracranial and subdural electrodes" technology are critical tools in neurology essential for electrocorticography and targeted cortical stimulation. But globally sourced electrodes are prohibitively expensive, limiting access in many parts of the world. To address this need, an indigenous development initiative was launched.
The "chitosan-based antioxidant polymeric wound dressings for controlled antibiotic delivery" is an advanced wound care material intended for treating chronic and infected wounds.
The last technology transfer made was on the reference materials for biological evaluations. For meeting the regulatory requirements in biocompatibility evaluations, as per international standards ISO 10993, a proof of concept project under TRC was completed at calibration cell, SCTIMST, for the development and standardisation of in-house reference biomaterials.
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