Colorectal cancer risk reduced by this common vitamin, study suggests
Vitamin D is widely known for boosting bone health, muscle strength and immune function, but it also has a range of other benefits — including cancer prevention.
A new study published in the journal Nutrients suggests that the common vitamin is effective in preventing and treating colorectal cancer.
Hungarian researchers conducted a meta-analysis of 50 previous studies that included more than 1.3 million participants, focusing on vitamin D's potential effects on cancer risk, immunity and inflammation.
"The most important finding is that vitamin D plays a critical role in the prevention and treatment of colorectal cancer," study author János Tamás Varga, PhD, associate professor at Semmelweis University in Budapest, told Fox News Digital.
"Our research clearly supports the strong correlation between 25-hydroxyvitamin D (the primary form of vitamin D) levels and cancer outcomes."
Cancer patients with low vitamin D levels showed poorer prognoses.
Vitamin D has been shown to reduce inflammation, promote the death of cancer cells, inhibit tumor growth and enhance immune response, the researchers found.
"These mechanisms significantly influence the pathophysiology of colorectal cancer," Varga noted.
In addition to prevention, vitamin D supplementation was also shown to improve survival rates among patients with advanced-stage colorectal cancer, according to the research.
"The results suggest that the effect of vitamin D may depend on factors such as the dosage, the individual condition of the patients and the duration of treatment," Vargas added.
The American Cancer Society (ACS) has previously referenced studies suggesting that vitamin D could lower cancer risk, particularly colorectal cancer.
"However, large studies have not found that vitamin D supplements lower the risk of colorectal polyps (pre-cancerous growths) or cancer," the ACS stated on its website.
"The optimal dosage should be tailored to the individual's health condition and current vitamin D levels."
One important limitation of the research is that the studies included in the analysis used different vitamin D dosages and involved patients at various stages of cancer, the authors noted.
They called for further research to accurately determine the optimal dosage and "therapeutic efficacy."
"Based on our research, we recommend that individuals at high risk of colorectal cancer monitor their vitamin D levels and, if necessary, take a daily vitamin D supplement of 1000–4000 IU, especially for those with low vitamin D levels," lead study author Dr. Monika Fekete, medical doctor at Semmelweis University, told Fox News Digital.
"The optimal dosage should be tailored to the individual's health condition and current vitamin D levels."
For physicians, the researchers suggest routinely measuring and supplementing vitamin D levels for both prevention and treatment purposes.
"Vitamin D plays a crucial role in the treatment and prevention of colorectal cancer, but further research is needed to determine the optimal dosage and the specific role of genetic factors," Fekete added.
"The molecular mechanisms of vitamin D — such as the regulation of oncogenes (mutated genes that can lead to cancer) and inhibition of tumor progression — require further scientific investigation."
As the effect of vitamin D is closely linked to the patient's condition, the doctor said, treatment recommendations should be personalized.
The primary source of vitamin D is exposure to the sun's ultraviolet (UV) rays.
It can also be obtained from dietary sources, according to the ACS, including fatty fish and some mushrooms.
There are also some vitamin D-fortified foods, including milk, some orange juices and cereals, the above source stated.
People can also take vitamin D supplements to boost their levels.
"Most Americans do not get enough vitamin D in their diets, and many have low vitamin D levels in their blood," the ACS said on its website.
"While the role of vitamin D in lowering cancer risk is still an active area of research and debate, avoiding low vitamin D levels is recommended."
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Lone Biden official breaks silence on cognitive decline as Cabinet stays mute
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In February 2024, following the release of the report, Biden shot back at Hur: "There's some attention paid to some language in the report about my recollection of events. There's even a reference that I don't remember when my son died. How in the hell dare he raise that?" Biden Struggles With Words, Key Memories In Leaked Audio From Special Counsel Hur Interview Harris called the report "gratuitous, inaccurate and inappropriate." The recently released audio recordings show it was Biden who brought up his son and could not remember when Beau died. "So, during this time when you were living at Chain Bridge Road and there were documents relating to the Penn Biden Center, or the Biden Institute, or the Cancer Moonshot or your book, where did you keep papers that related to those things that you were actively working on?" Hur asked Biden in the interview. "Well, um … I, I, I, I, I don't know. This is, what, 2017, 2018, that area?" Biden responded. "Yes, sir," Hur said. "Remember, in this timeframe, my son is either been deployed or is dying, and, and so it was and by the way, there were still a lot of people at the time when I got out of the Senate that were encouraging me to run in this period, except the president," Biden continued. "I'm not — and not a mean thing to say. He just thought that she (Hillary Clinton) had a better shot of winning the presidency than I did. And so I hadn't, I hadn't, at this point — even though I'm at Penn, I hadn't walked away from the idea that I may run for office again. But if I ran again, I'd be running for president. And, and so what was happening, though — what month did Beau die? Oh, God, May 30th." Others present during the interview responded that Beau Biden died in 2015. Trump has called an alleged cover-up of Biden's health a "scandal" and has argued that White House staffers were controlling the administration through the use of an autopen. What Is An Autopen? The Signing Device At The Heart Of Trump's Attacks On Biden Pardons Autopen signatures are automatically produced by a machine, as opposed to an authentic, handwritten signature. The conservative Heritage Foundation's Oversight Project first investigated the Biden administration's use of an autopen earlier in 2025 and found that the same signature was on a bevvy of executive orders and other official documents, while Biden's signature on the document announcing his departure from the 2024 race varied from the apparent machine-produced signature. "Whoever had control of the 'AUTOPEN' is looking to be a bigger and bigger scandal by the moment," Trump posted to Truth Social in article source: Lone Biden official breaks silence on cognitive decline as Cabinet stays mute
