logo
Dieters lose MORE weight on lower doses of slimming jabs - this is the precise amount that scientists found works best

Dieters lose MORE weight on lower doses of slimming jabs - this is the precise amount that scientists found works best

Daily Mail​12-07-2025
Patients on high doses of a popular weight-loss drug shed fewer pounds than those on a lower dose, a study has found.
GLP-1 inhibitor drug Mounjaro – also known as tirzepatide and dubbed the 'King Kong' of slimming jabs – can help patients shed up to a fifth of their body weight in just a year.
Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

How do I donate blood? NHS call for donors with rare blood types
How do I donate blood? NHS call for donors with rare blood types

The Independent

time19 minutes ago

  • The Independent

How do I donate blood? NHS call for donors with rare blood types

An initiative to help individuals with rare blood types secure a "precision-matched" donation to avoid the risk of severe reactions has been launched by the NHS. Scientists have embarked on a large-scale research project, DNA -testing the blood of 77,000 donors to date. Blood collected from these rare donors will be frozen, creating a vital reserve for others with the same specific blood type. Crucially, this stored blood will also be available to the donor themselves, should they ever require a transfusion. The reserve of rare blood donors will help avoid severe transfusion reactions, where the body sees the transfused blood as 'foreign' and rejects it. People who are particularly at risk of these reactions are those who regularly receive blood donations, including those with sickle cell disorder and thalassaemia. It comes after the NHS raised the alarm over low blood stocks last month. The NHS said it needed 200,000 more regular blood donors to sustain a safe and sufficient supply. Low blood stocks in 2024 prompted an "amber alert', but blood stocks have remained low ever since. NHS Blood and Transplant (NHSBT) is now urging more people to donate to avoid a "red alert", which is a critical situation where public safety is threatened. It described the past year as "challenging" for blood stocks, noting that just under 800,000 people are supporting the entire blood supply in England. How do I donate blood? The whole process of giving blood takes just one hour. When arriving at a blood donation centre, you are asked to complete a safety check to make sure you can give blood. You will be given 500ml of fluid to drink – drinking this will help the body maintain blood pressure, prevent dizziness and help the body replenish the donated blood. Then, to ensure it is safe to donate blood, medics will confirm your identity and information during a health check. In some cases, a registered nurse will follow it up. A drop of blood from your finger is then checked for iron levels. If these levels are too low, the appointment will be rescheduled. Those able to donate will be seated in the waiting area before being called to a donation chair. Here, a cuff will be placed on your arm to maintain a small amount of pressure during the donation before a suitable vein is found and the area is cleaned. Then, a needle will be inserted into your arm to collect your blood into a blood bag, which has your unique donor number on it. A scale weighs the blood and stops when you have donated 470ml - that's just under a pint. The needle is then removed from your arm, and a dressing is applied. The NHS says the process of giving blood should not hurt and should only take about 10 minutes. Who can donate blood? Although more donors are needed, some health, travel and lifestyle reasons may stop you from donating blood. Donors need to be fit and well, aged between 17 and 65, weigh between 7 stone 12 Ibs (50kg) and 25 stone (158kg) and have suitable veins. However, you can't donate blood if you have cancer, some heart conditions, have tested positive for HIV or are a hepatitis B or C carrier. If you have received blood platelets, plasma or any other blood products after January 1980, or if you have injected non-prescribed drugs including body-building and injectable tanning agents, you also cannot donate. If you've had anal sex with a new partner in the last three months, you may have to postpone your donation. If you feel unwell, are pregnant or have had a baby in the last six months, have had a tattoo or piercing, or have recently travelled to certain countries outside the UK, you may also have to wait before you can donate blood. Where can I donate blood? There are thousands of blood donation venues across England, some are permanent and others are pop-ups. Church halls, sports centres, mosques, football stadiums and hotels are all used as pop-up venues. To check where your closest one is, visit the Give Blood website. You will need to book an appointment ahead of your donation, which can be done online as soon as you have signed up as a blood donor. What type of blood is needed? There is a 'critical' need for more donors who have the so-called universal blood type, O negative blood, which is needed for treatment in emergencies. The NHS said there is also a need for more Black donors, who are more likely to have specific blood types which can help treat people with sickle cell disease.

I lost 3st in just 6 months on Mounjaro – but the best bit is a rampant side-effect I wasn't expecting
I lost 3st in just 6 months on Mounjaro – but the best bit is a rampant side-effect I wasn't expecting

Scottish Sun

time19 minutes ago

  • Scottish Sun

I lost 3st in just 6 months on Mounjaro – but the best bit is a rampant side-effect I wasn't expecting

Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A WOMAN who lost nearly 3 stone in just six months on Mounjaro says weight loss wasn't the only benefit - as she made the most of a "sexy" side effect. Jackie Collins, 44, was a size 18 at her heaviest and decided to try a weight loss job after being caught in a "vicious circle" of dieting and binge eating. Sign up for Scottish Sun newsletter Sign up 8 Jackie Collins, 44, decided to try Mounjaro after being caught in a cycle of dieting and bingeing Credit: SWNS 8 Jackie weighed 17st 11lbs but saw the pounds drop off her every week Credit: SWNS 8 Now 14st, Jackie has benefited from an unexpected side effect from her weight loss Credit: SWNS After a friend suggested she try Mounjaro, within weeks Jackie began to notice her hunger reducing. She went from eating bags of crisps, chocolate and big portions of creamy pasta to fruit, salads and protein rich meals. Since starting Mounjaro in February on a 2.5mg dosage, Jackie has moved up through the doses, dropping from 17st 11lbs to 15st exactly and fitting into a size 14. She now plans to incorporate some exercise into her new lifestyle after purchasing a bike. But Jackie has had an unexpected side effect from Mounjaro. Jackie says the jabs have reignited the "passion" in her sex life with her partner, Carl, 44. The couple have gone from being having sex a couple of times a month to four times a week. Jackie, who works for a shop fitting company from Southampton, Hampshire, said: "Before, the times we were intimate were few and far between - I didn't feel sexy, so how could he find me sexy? "It never happened. I always said it was never him; it was me. "But since I've started getting that confidence back, the passion's come back. Towie star Saffron Lempriere reveals how she lost 12 pounds in 4 weeks - without fat jabs "We've gone from a couple of times a month to three or four times a week. "We're like kids again, which is great." Jackie knew she needed to make a change after finding that diets and walks weren't helping. She said: "I'd been struggling to lose weight for so long. 8 Jackie wasn't able to wear this red dress without the buttons popping open but now she feels 'amazing' in it Credit: SWNS 8 She and her partner Carl have gone from having sex a couple of times a month to four times a week Credit: SWNS 8 Mounjaro has left Jackie feeling confident and sexy Credit: SWNS "Diets would spark out and I'd comfort eat and binge eat again - it was a vicious circle. "Last October, I did a charity walk for motor neurone disease. "When I walk, I march and I did the 75 miles in 3 weeks and I lost 2lbs - that was it. "I thought something wasn't right. Jackie's diet before and after her weight loss Jackie has found it easier to eat healthily since starting on Mounjaro. Her diet before consisted of: Breakfast: Nothing Lunch: Sandwich, packet of crips and a chocolate bar, snack on sweets Dinner: Big bowl of creamy pasta, big bags of crips Since starting on the jabs, this is what she's eaten: Breakfast: Bran flakes, with banana or other fruit Lunch: Tuna salad Dinner: Couple of pork steaks with sweetcorn and jacket potato "Mounjaro came up and I was told to try it by a friend. "So I did, and it's been brilliant. "The weight's been coming a few lbs every week - I can see so much difference and in my clothes. "I started off on 2.5mg and I would find the day after the jab I was a bit tired initially, but that was it. "The hunger wasn't there - I was very food orientated, and I'd have it on my mind all the time and a few weeks after I started it, that's when I really noticed that my hunger wasn't there. "You think you're hungry, you go to eat and you're not. "I'm now eating correctly, have lots of protein and more water. "Now my body is getting used to it, I fancy meals, but I don't eat as much. "I was plating up a roast dinner for everyone yesterday, but I hardly put anything on my plate, and I don't have to think about it." Jackie says her new look has given her confidence - allowing her to" feel and look good." She said: "I've got so much more confidence. "A while ago I bought a red dress and when I wore it all the buttons were popping. "I went and saw Craig David and now I was able to wear the dress and I felt amazing. "I felt and looked good." 8 Jackie before her weight loss Credit: SWNS 8 Jackie said she and Carl are 'like kids again' Credit: SWNS

I've gone from a size 18 to an 8 in 9 months on Mounjaro & still losing weight, I was sick for weeks but it was worth it
I've gone from a size 18 to an 8 in 9 months on Mounjaro & still losing weight, I was sick for weeks but it was worth it

Scottish Sun

time19 minutes ago

  • Scottish Sun

I've gone from a size 18 to an 8 in 9 months on Mounjaro & still losing weight, I was sick for weeks but it was worth it

Read on for more warnings on using Mounjaro WEIGH TO GO! I've gone from a size 18 to an 8 in 9 months on Mounjaro & still losing weight, I was sick for weeks but it was worth it Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) A WOMAN who has managed to shift over six stone thanks to Mounjaro has shared the side effects she suffered. Sophie Barrella took to social media to share her incredible transformation, and people were stunned by the results. Sign up for Scottish Sun newsletter Sign up 2 Sophie Barrella started taking the weight loss jab nine months ago Credit: Facebook 2 Depsite having side effects, she said it was so worth it for the weight loss Credit: Facebook The mum said she started her weight loss journey nine months ago and had already shed 6.5 stone. She started her journey at 15.7st and a size 18, and in less than a year has gone down to a size 8. In the image, the mum could be seen with her partner and child before losing weight. She wore a one-sleeve dress and was turned to the side and looked obviously larger. But now, in the pictures of her weight loss, the mum wore a tight fitting pink dress to show off her new body and beamed at the camera. She captioned the post: "9 months later and I'm down 6 and a half stone! "Finished June 2025 at current 9 stone 3 and still loosing! Size 8. "Worth every penny and side effect I suffered!!" In the comments of the Facebook post, Sophie shared just some of the side effects she suffered from. She wrote: "I found I had headaches from 5mg, then the nausea crept in. Then from 7.5 and 10mg I have had constant grumbling in my stomach, so badly it wakes me up every single night for the next 4 days after injecting and I would have sickness 3-4 times a night. I've lost nearly 6 stone in 9 months on fat jabs - trolls call me 'lazy' & say it's the 'easy way out' but I don't care "Could only sleep on my back because when I was on my side the gas in my stomach would gurgle so loudly and caused me a lot of pain, but again, only 4 days after injecting! Then I would be okay until jab day. "Was honestly worth it all. If you're thinking about it, just go for it! Will change your life." The post was shared on the Facebook group, Mounjaro Ozempic Wegovy weight loss support, where those on the weight loss jabs come together to support each other. Many were quick to congratulate Sophie on her weight loss. One person wrote: "How have you not managed to have excess skin. You look amazing." Another commented: "Well done!" "Well done fantastic achievement," penned a third. What to do if you lose too much weight too quickly whilst on Mounjaro IF you're losing too much weight too quickly while on Mounjaro, it's important to take action to avoid potential health risks like muscle loss, malnutrition, dehydration, and fatigue. Here's what you can do: Evaluate Your Caloric Intake Mounjaro reduces appetite, which can make it easy to eat too little. If you're losing weight too fast (more than two to three lbs per week after the initial adjustment period), try: Tracking your food intake to ensure you're eating enough calories (apps like MyFitnessPal can help). Increasing protein intake to preserve muscle mass (aim for 0.6–1g per pound of body weight). Adding healthy fats and complex carbs (e.g., avocados, nuts, whole grains) for balanced energy. Adjust Your Dosage (With Doctor's Approval) If your weight loss is too rapid or causing side effects, your doctor may: Pause dose increases or lower your dosage. Adjust your treatment plan to stabilise your weight loss. Strength Training & Exercise To prevent muscle loss: Incorporate resistance training at least two to three times per week. Stay active with low-impact exercises like walking or yoga. Hydrate & Manage Electrolytes Drink enough water (Mounjaro can reduce thirst). Electrolytes matter - Consider adding magnesium, sodium, and potassium if you feel weak or fatigued. Monitor for Malnutrition & Deficiencies Rapid weight loss can cause vitamin/mineral deficiencies (especially B12, iron, and electrolytes). If you experience: Fatigue, hair loss, or dizziness, ask your doctor about supplements. Consider Further Medical Guidance If your weight loss is excessive or causing health concerns, speak with your healthcare provider. They might adjust your dosage, diet, or exercise plan to help stabilise your weight loss. Meanwhile a fourth said: "You look stunning!" "You look amazing,' claimed a fifth Someone else added: "Gorgeous!"

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store