Latest news with #slimmingjabs
Daily Mail
31-07-2025
- Health
- Daily Mail
How to reverse saggy Ozempic or Mounjaro face, by top beauty editor INGE VAN LOTRINGEN who reveals exactly what really works
An estimated one in ten women in the UK are using slimming jabs. But with rapid weight loss comes 'Ozempic face' – hollowed cheeks, sagging skin and more wrinkles.
Daily Mail
13-07-2025
- Health
- Daily Mail
Why slimmers using weight-loss shots are at risk of losing their libido
Experts have sounded the alarm over a bizarre side effect that may be triggered by slimming jabs: a drop in sex drive. Once aimed at diabetes patients, drugs like Mounjaro and Wegovy are now famous for bringing about rapid weight loss by reducing appetite - but it seems they're also slimming down libidos, too. The injections' side effects have been widely discussed, ranging from nausea and constipation to life-threatening organ damage, but now, top psychologists have warned that the medication may cause users' libidos to plummet because of how it impacts a certain brain chemical. Such is the concern among users of the drug, that hundreds have taken to online forums sharing how the drugs altered their sex drive, warning others that it was the 'price they paid for no longer being fat'. The injections spurs weight loss by mimicking the actions of a hormone released by in the gut after eating - GLP-1. As well as telling the pancreas to make more insulin, GLP-1 feeds back to the brain and makes us feel full - stopping patients from over-eating. According to Professor Rachel Goldman, a clinical pyschologist at New York University, GLP-1 drugs target 'the reward center in the brain', which is why people experience 'less food noise, fewer craving and less interest in alcohol use'. She told PureWow: 'It's also why what might impact your sex drive.' Dr Kent Berridge, a professor of psychology and neuroscience at the University of Michigan, also previously told that having sex with a partner, thinking of having sex with them and seeing them would normally trigger sexual desire, 'just like drug use triggers desire for drugs'. 'But if you're suppressing [dopamine activation] a little bit and cutting down those mountain peaks, sexual desire is a natural peak, so that would be plausible. Dr Berridge said: 'Now, how is it doing that? How is it suppressing dopamine systems? That we do not know.' 'It may be partly acting right on the nucleus accumbens [the brain structure known for its role in pleasure, reward and addiction], because there are receptors there.' One British study published last year in QJM: An International Journal of Medicine found new patients on the drug may experience cognitive changes in their decision-making, partly from the calorie deficit the drug induces, as well as the effects of GLP-1 on brain function. The researchers said: 'This isn't as far-fetched as it might sound.' Another 2024 study also suggested that obese men who were taking semaglutide, the active ingredient in Ozempic and Wegovy, were at a slightly higher risk of erectile dysfunction than men with obesity who weren't taking the drug. However, they added that further research needs to be done to 'understand possible underlying biologic pathways that result in sexual dysfunction side effects'. But the phenomenon has become so common that forum users are even sharing how the drugs have slashed their libido. In one Reddit forum with over 142,000 members, one user said: 'Before we started with Mounjaro we had a low but regular sex life, that was manly slowed down by us both feeling not comfortable with our bodies. 'Since Mounjaro we have developed in different directions: I feel comfortable with my body and sexy the first time in my life and I'm really horny all the time, while my wife has no sex drive at all - even though she looks marvelous. 'She says she feels like don't wanting sex at all since taking Mounjaro. So is the price for no longer being fat, the end of an active sex life?' Another wrote: 'Anyone else have a completely depleted sex drive? 'Ever since I've been on Mounjaro - second month now- I've noticed that no matter what I genuinely do not feel anything.' A third added: 'I've been on Tirzepatide [the ingredient behind Mounjaro] since February and I definitely have a much lower sex drive than I used to. 'It's really unfortunate because I feel a lot more confident in my body now but generally just don't have a desire to do anything.' According to Professor Goldman, however, the drugs may not directly be the cause of the new cause of friction in relationships. Instead, it is likely due to weight loss in general, which is 'nothing new', she said. One 2018 Swedish study of post-bariatric surgery patients found that that bariatric surgery patients who were married were 41 percent more likely to get divorced, compared to people in the general population. Rapid weight loss can affect hormone balance, as can a restricted diet, by reducing amounts of essential sex hormones testosterone and estrogen.
Daily Mail
12-07-2025
- Health
- Daily Mail
Dieters lose MORE weight on lower doses of slimming jabs - this is the precise amount that scientists found works best
Patients on high doses of a popular weight-loss drug shed fewer pounds than those on a lower dose, a study has found. GLP-1 inhibitor drug Mounjaro – also known as tirzepatide and dubbed the 'King Kong' of slimming jabs – can help patients shed up to a fifth of their body weight in just a year.
Daily Mail
11-07-2025
- Health
- Daily Mail
Top psychologist issues warning about unwelcome Mounjaro sex side effect which is destroying happy relationships
Experts have sounded the alarm over a bizarre side effect that may be triggered by slimming jabs: a drop in sex drive. Once aimed at diabetes patients, drugs like Mounjaro and Wegovy are now famous for bringing about rapid weight loss by reducing appetite—but it seems they're also slimming down some users' libidos, too. The injections' side effects have been widely discussed, ranging from nausea and constipation and, in the most severe cases, life-threatening organ damage. Now, top psychologists have warned that the medication may cause users' libidos to plummet because of how it impacts a certain brain chemical. Such is the concern among jab users, that hundreds have taken to online forums sharing how the drugs altered their sex drive, warning others that it was the 'price they paid for no longer being fat'. The injections spurs weight loss by mimicking the actions of a hormone released by in the gut after eating—GLP-1. As well as telling the pancreas to make more insulin, GLP-1 feeds back to the brain and makes us feel full—stopping patients from over-eating. According to Professor Rachel Goldman, a clinical pyschologist at New York University, GLP-1 drugs target 'the reward center in the brain', which is why people experience 'less food noise, fewer craving and less interest in alcohol use'. She told PureWow: 'It's also why what might impact your sex drive.' Dr Kent Berridge, a professor of psychology and neuroscience at the University of Michigan, also previously told MailOnline that having sex with a partner, thinking of having sex with them and seeing them would normally trigger sexual desire, 'just like drug use triggers desire for drugs'. 'But if you're suppressing [dopamine activation] a little bit and cutting down those mountain peaks, sexual desire is a natural peak, so that would be plausible. 'Now, how is it doing that? How is it suppressing dopamine systems? That we do not know,' Dr Berridge said. 'It may be partly acting right on the nucleus accumbens [the brain structure known for its role in pleasure, reward and addiction], because there are receptors there.' One British study published last year in QJM: An International Journal of Medicine found new patients on the drug may experience cognitive changes in their decision-making, partly from the calorie deficit the drug induces, as well as the effects of GLP-1 on brain function. 'This isn't as far-fetched as it might sound,' the researchers said. Another 2024 study also suggested that obese men who were taking semaglutide, the active ingredient in Ozempic and Wegovy, were at a slightly higher risk of erectile dysfunction than men with obesity who weren't taking the drug. The researchers found that females between the ages of 20 and 59 who had sex less than once a week were at a 70 per cent increased risk of death within five years However, they added that further research needs to be done to 'understand possible underlying biologic pathways that result in sexual dysfunction side effects'. But the phenomenon has become so common that forum users are even sharing how the drugs have slashed their libido. In one Reddit forum with over 142,000 members, one user said: 'Before we started with Mounjaro we had a low but regular sex life, that was manly slowed down by us both feeling not comfortable with our bodies. 'Since Mounjaro we have developed in different directions: I feel comfortable with my body and sexy the first time in my life and I'm really horny all the time, while my wife has no sex drive at all—even though she looks marvellous. 'She says she feels like don't wanting sex at all since taking Mounjaro. So is the price for no longer being fat, the end of an active sex life?' Another wrote: 'Anyone else have a completely depleted sex drive? 'Ever since I've been on Mounjaro—second month now—I've noticed that no matter what I genuinely do not feel anything.' A third added: 'I've been on Tirzepatide [the ingredient behind Mounjaro] since February and I definitely have a much lower sex drive than I used to. 'It's really unfortunate because I feel a lot more confident in my body now but generally just don't have a desire to do anything.' According to Professor Goldman, however, the drugs may not directly be the cause of the new cause of friction in relationships. Instead, it is likely due to weight loss in general, which is 'nothing new', she said. One 2018 Swedish study of post-bariatric surgery patients found that that bariatric surgery patients who were married were 41 percent more likely to get divorced, compared to people in the general population. Rapid weight loss can affect hormone balance, as can a restricted diet, by reducing amounts of essential sex hormones testosterone and estrogen. At least half a million NHS patients and some 15 million patients in the US are now thought to be using weight-loss jabs, which can help patients lose up to 20 per cent of their body weight in just a few months. And the numbers using them privately are even higher. The health service currently prescribes Wegovy to around 35,000 patients at specialist weight management clinics. Mounjaro, meanwhile, has been available in similar clinics since March and as of this month, GPs are also able to prescribe it. The drug warning also comes amid concern about a global sex crisis—or rather, lack of sex crisis. One recent survey revealed more than a quarter (27 per cent) of Britons are now having less sex than they used to, with one in six admitting they haven't got frisky the entire year. According to a Royal College of Occupational Therapists poll of 2,000 adults last year, men and women typically only have sex 46 times a year — once every eight days. But some have far less frequent amorous activity, with a tenth reported having sex less than once a year. Last month, researchers at the University of Manchester, also revealed women who have sex at least once a week are the happiest in their relationships. Their study showed that 85 per cent of women who had sex once a week described themselves as 'sexually satisfied'. In contrast, only 17 per cent of women who had sex less than once a month reported the same level of relationship bliss. Sex and intimacy have been linked to several health benefits, including improving the condition of your heart, reducing stress and even boosting mental health.
Daily Mail
17-06-2025
- Health
- Daily Mail
Weight loss jabs like Mounjaro now linked to more than a HUNDRED deaths, the UK's drug watchdog confirms
Slimming jabs like Mounjaro and Wegovy have been linked to more than 100 deaths in Britain, it was revealed today. None of the fatalities, which have all been reported since the jabs were licensed for use in the UK, are proven to have been caused directly by the drugs. However, health chiefs tasked with policing the safety of medicines admit reports of side effects indicate 'a suspicion' they may have been to blame. A total of 111 deaths were logged with the regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), up to and including May 29. These are based on patients' families or healthcare workers informing the MHRA of a suspected fatal reaction to the drugs, known as glucagon-like peptide-1 receptor agonists (GLP-1RAs). It comes just months after the death Scottish nurse Susan McGowan, 58, who experienced multiple organ failure, septic shock and pancreatitis after taking just two doses of Mounjaro. Hers is the only confirmed fatality linked to the jabs in the UK. But it comes at a time when ministers are planning to rollout the jabs—described as game changers in the fight against obesity— to even more Britons. The deaths may also be caused by underlying medical conditions or other medications taken at the same time and therefore can be coincidental the MHRA told trade magazine Chemist+Druggist. Officials use the MHRA's 'Yellow Card' database, set-up in the wake of the 1960s thalidomide scandal, to track the safety of medications currently in use in Britain. Although almost impossible to prove, the system allows doctors, pharmacists and patients to report adverse reactions they believe are linked to medications and allows officials to uncover potential patterns. The weight-loss medication linked to the most deaths, in the system was liraglutide—sold under the brand name Saxenda—with 37 reports of a fatal outcome. In second place was tirzepatide—sold as Mounjaro and once hailed the 'King Kong' of slimming jabs—with 33 deaths. And in third place was semaglutide—the active ingredient in the weight loss jab Wegovy as well diabetes drug Ozempic—which was linked to 30 deaths. A further seven reports were liked to dulaglutide—known as Trulicity—and five to lixisenatide—which has the trade name Lyxumia. Of the total fatal reports, 32 involved jabs indicated for 'weight management alone or 'only licensed for weight management—Mounjaro, Saxenda, Wegovy'. Meanwhile, 40 reports related to drugs with an indication for 'diabetes alone'. Another nine referred to patients getting the jab for 'both weight management or diabetes'. While 30 reported a fatal outcome 'with an indication other than weight management or diabetes, or where no indication has been reported', the watchdog told Chemist+Druggist. Last year, medics warned they were seeing a wave of patients of healthy weight taking the drugs in a bid to become 'beach-body ready'. Such patients, mostly young women, were landing in A&E after obtaining the drugs online under false pretences. Currently, patients can obtain the drugs from many chemists by filling in online forms with details of their weight and height and submitting photographs of themselves. However, experts and organisations such as the Society for Acute Medicine have called for tighter restrictions on how Ozempic, Mounjaro and other weight-loss products are prescribed. A spokesperson for Lilly UK, the makers of Mounjaro, said patient safety is its 'top priority'. It added: 'Regulatory agencies conduct extensive independent assessments of the benefits and risks of every new medicine and Lilly is committed to continually monitoring, evaluating, and reporting safety data.' 'If anyone is experiencing side effects when taking any Lilly medicine, they should talk to their doctor or other healthcare professional.' There has been growing concern after reports of side effects from the drugs. These include including nausea, vomiting, diarrhoea, bone fractures, tooth damage, severe anxiety and depression. Earlier this month, women reported terrifying mental health side effects after using Mounjaro. The jab, along with similar treatments such as Ozempic and Wegovy, can help patients lose up to 15 per cent of their body weight in a year.
