RFK Jr. and other Trump officials embrace psychedelics after FDA setback
A presidential administration finally seems to agree.
"This line of therapeutics has tremendous advantage if given in a clinical setting and we are working very hard to make sure that happens within 12 months," Health Secretary Robert F.
Kennedy
Jr. recently told members of Congress.
His suggested timeline for green-lighting psychedelic therapy surprised even the most bullish supporters of the drugs. And it comes as psychedelics are making inroads in deep red states like Texas, where former
Trump
cabinet secretary and ex-governor Rick Perry has thrown his full support behind the effort.
The administration's embrace of psychedelics has sparked both excitement as well as concern from those in the field, who worry the drugs might be discredited if they appear to be rushed onto the market or are too closely linked with Kennedy, who is known for controversial views on vaccines, antidepressants and fluoride.
"I'm quite optimistic," says Rick Doblin, whose organization has pursued the medical use of MDMA (or ecstasy) since the 1980s. "But I'm also worried that the message the public might get is 'Well,
RFK
likes psychedelics and now it's approved.'"
FDA
may reconsider MDMA Under President Joe Biden, the FDA rejected MDMA as a treatment for post-traumatic stress disorder, citing flawed data and questionable research. Regulators called for a new study, likely taking several years. It was a major setback for Doblin and other advocates hoping to see the first U.S. approval of a psychedelic for medical use.
But the agency appears ready to reconsider. FDA chief Marty Makary, who reports to Kennedy, has called the evaluation of MDMA and other psychedelics "a top priority," announcing a slate of initiatives that could be used to accelerate their approval.
One new program promises to expedite drugs that serve "the health interests of Americans," by slashing their review time from six months or more to as little as one month. Makary has also suggested greater flexibility on requirements for certain drugs, potentially waiving rigorous controlled studies that compare patients to a placebo group.
That approach, considered essential for high-quality research, has long been a stumbling point for psychedelic studies, in which patients can almost always correctly guess whether they've received the drug or a dummy pill.
The U.S. Department of Health and Human Services and FDA also recently hired several new staffers with ties to the psychedelic movement.
"These are all very promising signs that the administration is aware of the potential of psychedelics and is trying to make overtures that they're ready to approve them," said Greg Ferenstein, a fellow at the libertarian Reason Foundation, who also consults for psychedelic companies. "We didn't hear anything about that in the Biden administration"
A spokesperson for HHS did not respond to a request for comment.
As a presidential candidate, Kennedy discussed how his son and several close friends benefited from using psychedelics to deal with grief and other issues.
A number of veterans lobbying for psychedelic access have already met with Trump's Secretary of Veterans Affairs, Doug Collins.
"What we're seeing so far is positive," Collins told House lawmakers in May.
But some experts worry the hope and hype surrounding psychedelics has gotten ahead of the science.
Philip Corlett, a psychiatric researcher at Yale University, says bypassing rigorous clinical trials could set back the field and jeopardize patients.
"If RFK and the new administration are serious about this work, there are things they could do to shepherd it into reality by meeting the benchmarks of medical science," Corlett said. "I just don't think that's going to happen."
Texas goes all-in on ibogaine research As officials in Washington weigh the future of psychedelics, some states are moving ahead with their own projects in hopes of nudging the federal government. Oregon and Colorado have legalized psychedelic therapy.
And last month, Texas approved $50 million to study ibogaine, a potent psychedelic made from a shrub that's native to West Africa, as a treatment for opioid addiction, PTSD and other conditions. The research grant - the largest of its kind by any government - passed with support from the state's former GOP governor, Perry, and combat veterans, some who have traveled to clinics in Mexico that offer ibogaine.
Ibogaine is on the U.S. government's ultra-restrictive list of illegal, Schedule 1 drugs, which also includes heroin. So advocates in Texas are hoping to build a national movement to ease restrictions on researching its use.
"Governmental systems move slowly and inefficiently," said Bryan Hubbard of Americans for Ibogaine, a group formed with Perry. "Sometimes you find yourself constrained in terms of the progress you can make from within."
Ibogaine is unique among psychedelics in both its purported benefits and risks. Small studies and anecdotal reports suggest the drug may be able to dramatically ease addiction and trauma. It was sold for medical use in France for several decades starting in the 1930s, but the drug can also cause dangerous irregular heart rhythms, which can be fatal if left untreated.
Some veterans who have taken the drug say the risks can be managed and ibogaine's healing properties go far beyond antidepressants, mood stabilizers, counseling and other standard treatments.
Marcus Capone struggled with anger, insomnia and mood swings after 13 years as a Navy Seal. In 2017, at the urging of his wife Amber, he agreed to try ibogaine as a last resort. He described his first ibogaine session as "a complete purge of everything."
"But afterward I felt the weight just completely off my shoulders," he said. "No more anxiety, no more depression, life made sense all of a sudden."
A nonprofit founded by the Capones, Veterans Exploring Treatment Solutions, or VETS, has helped over 1,000 veterans travel abroad to receive ibogaine and other psychedelics.
But federal scientists have looked at the drug before - three decades ago, when the National Institute on Drug Abuse funded preliminary studies on using it as an addiction treatment. The research was discontinued after it identified "cardiovascular toxicity."
"It would be dead in the water," in terms of winning FDA approval, longtime NIDA director Nora
Volkow
said.
But Volkow said her agency remains interested in psychedelics, including ibogaine, and is funding an American drugmaker that's working to develop a safer, synthetic version of the drug.
"I am very intrigued by their pharmacological properties and how they are influencing the brain," Volkow said. "But you also have to be very mindful not to fall into the hype and to be objective and rigorous in evaluating them."
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