ChristianaCare opens new micro-hospital in Chester County, Pennsylvania, filling gap in health care
ChristianaCare is launching three micro-hospitals in the Philadelphia region, starting with the first one in West Grove, which sits on the site of the former Jennersville Hospital. That facility shut down in 2021, leaving residents with long drives for emergency care.
Kate Ramirez, director of nursing at ChristianaCare West Grove, is one of 90 staff members hired to run the new 20,000-square-foot facility.
"I'm really excited," Ramirez said. "I'm local, like I said before, close to home. So we really needed something in this area."
Micro-hospitals are smaller than traditional hospitals. Officials said West Grove is equipped to handle most emergencies, including strokes and heart attacks.
Severe trauma, major surgery and STEMI heart attacks will require a different level of care, Dr. Vinay Maheshwari, physician executive for ChristianaCare, said.
"We do not have an intensive care unit," Dr. Maheshwari said. "We do not have an operating room, so we don't have those types of capabilities, but we can manage the great majority of the conditions that are required from an emergency perspective."
The West Grove micro-hospital offers advanced diagnostic tools, such as a CT scanner, and provides around-the-clock care.
"Our hospital here has the capabilities for lab services that are not found in urgent care," James Bennett, Market CEO for ChristianaCare-Emerus, said. "We have board-certified emergency physicians 24/7."
Before this, people had to drive 45 minutes away to Christiana Hospital in Newark or Chester County Hospital in West Chester for emergency care.
For West Grove residents like Ray Moyer, the return of a local emergency facility brings peace of mind.
"It makes me feel a lot more comfortable if I have an issue or if some of the neighbors have issues that there's a place close by for them to get immediate care," Moyer said. "At least they can stabilize you and then transport you. It's better than if you have a major issue having no nearby care. So I think it's a significant improvement."
In addition to West Grove, ChristianaCare plans to open micro-hospitals in Springfield and Aston, both in Delaware County.
The West Grove facility is expected to open in mid-August. In the meantime, signs have been posted outside letting the public know the hospital is not open yet, after some residents already showed up seeking services.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
17 minutes ago
- Yahoo
FDA Approves Apellis' EMPAVELI® (pegcetacoplan) as the First C3G and Primary IC-MPGN Treatment for Patients 12 and Older
Proven efficacy across all three key markers of disease—68% reduction in proteinuria, stabilization of kidney function, and substantial clearance of C3 deposits Broad label includes adults and adolescents with C3G or primary IC-MPGN, and post-transplant C3G disease recurrence Well-established safety profile, consistent across >2,200 patient years in approved indications C3G and primary IC-MPGN are rare kidney diseases with high risk of kidney failure Conference call tomorrow at 8:00 a.m. ETWALTHAM, Mass., July 28, 2025 (GLOBE NEWSWIRE) -- Apellis Pharmaceuticals, Inc. (Nasdaq: APLS) today announced that the U.S. Food and Drug Administration (FDA) has approved EMPAVELI® (pegcetacoplan) as the first treatment for C3 glomerulopathy (C3G) or primary immune complex membranoproliferative glomerulonephritis (IC-MPGN) in patients 12 years of age and older, to reduce proteinuria. C3G and primary IC-MPGN are rare kidney diseases, affecting 5,000 people in the United States.1 'I'm excited to now have a highly effective therapy for a broad range of patients living with C3G and primary IC-MPGN,' said Carla Nester, M.D., MSA, FASN, lead principal investigator for the VALIANT study, professor of internal medicine and pediatrics and director of pediatric nephrology, University of Iowa Stead Family Children's Hospital. 'With standard of care, patients living with these rare and severe diseases frequently progress to kidney failure, necessitating lifelong dialysis and/or a kidney transplant. Given the urgent need, particularly in children, the approval of EMPAVELI marks a pivotal moment in the treatment of rare kidney diseases.' In the Phase 3 VALIANT study, EMPAVELI demonstrated an unprecedented 68% reduction in proteinuria, stabilization of kidney function, and substantial clearance of C3 deposits as measured by C3 staining, compared to placebo. The positive results were consistent across adolescent and adult patients with C3G and primary IC-MPGN, and in C3G patients with post-transplant disease recurrence. 'EMPAVELI has the potential to be truly transformational for patients with C3G and primary IC-MPGN, who until now have had very few treatment options. In the largest pivotal study of these diseases, EMPAVELI demonstrated its potential to preserve kidney function by controlling all three key markers of disease,' said Cedric Francois, M.D., Ph.D., co-founder and chief executive officer, Apellis. 'As Apellis' third approval in four years, this milestone underscores the unique ability of targeting C3 to improve patients' lives. We are deeply grateful to everyone who made this approval possible and look forward to building on this momentum as we advance pivotal studies of EMPAVELI in other rare kidney diseases.' 'The approval of EMPAVELI is a historic milestone for people living with C3G and primary IC-MPGN, many of whom are adolescents or young adults,' said Josh Tarnoff, chief executive officer, NephCure. 'We recognize Apellis' commitment to these patients and their families, and to the research and innovation that will bring this life-changing treatment into the hands of patients that need it most.' The approval of EMPAVELI is based on positive six-month results from the VALIANT study, demonstrating benefits across all three key markers of disease: Proteinuria reduction: The study met its primary endpoint, demonstrating a statistically significant 68% (p<0.0001) proteinuria reduction in EMPAVELI-treated patients compared to placebo. Stabilization of kidney function: EMPAVELI-treated patients achieved stabilization of kidney function compared to placebo (nominal p=0.03) as measured by estimated glomerular filtration rate (eGFR). Reduction of C3 staining: A majority of EMPAVELI-treated patients achieved a reduction in C3 staining intensity (nominal p<0.0001) compared to placebo. 71% of EMPAVELI-treated patients achieved zero C3 staining intensity, demonstrating complete clearance of C3 deposits. The safety profile of EMPAVELI is well-established, with >2,200 patient years across all approved indications. The most common adverse reactions in the VALIANT study (≥10%) were infusion site reactions, pyrexia, nasopharyngitis, influenza, cough, and nausea. Apellis is committed to helping patients with treatment access and support. ApellisAssist® is a program designed to help EMPAVELI patients along their treatment journey by providing a comprehensive system of support including help navigating insurance coverage, financial assistance for eligible patients, disease education, and ongoing product support. Patients and healthcare providers can call 1-888-273-5547 for more information. Conference Call and WebcastApellis will host a conference call and webcast to discuss the FDA's approval of EMPAVELI tomorrow, July 29, 2025 at 8:00 a.m. ET. To access the live call by phone, please pre-register for the call here. A live audio webcast of the event and accompanying slides may also be accessed through the 'Events and Presentations' page of the 'Investors and Media' section of the company's website. A replay of the webcast will be available for 30 days following the event. About C3 Glomerulopathy (C3G) and Primary Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN)C3G and primary IC-MPGN are rare and debilitating kidney diseases that can lead to kidney failure. Excessive C3 deposits are a key marker of disease activity, which can lead to kidney inflammation, damage, and failure. Approximately 50% of people living with C3G and primary IC-MPGN suffer from kidney failure within five to 10 years of diagnosis, requiring a burdensome kidney transplant or lifelong dialysis therapy.2-4 Additionally, approximately 90% of patients who previously received a kidney transplant will experience disease recurrence.5 The diseases are estimated to affect 5,000 people in the United States and up to 8,000 in Europe.1 About the VALIANT StudyThe VALIANT Phase 3 study (NCT05067127) was a randomized, placebo-controlled, double-blinded, multi-center study that evaluated EMPAVELI® (pegcetacoplan) efficacy and safety in 124 patients who were 12 years of age and older with C3G or primary IC-MPGN. It is the largest single trial conducted in these populations and the only study to include pediatric and adult patients, with native and post-transplant kidneys. Study participants were randomized to receive EMPAVELI or placebo twice weekly for 26 weeks. Following this 26-week randomized controlled period, patients were able to proceed to a 26-week open-label phase in which all patients received EMPAVELI. The primary endpoint of the study was the log transformed ratio of urine protein-to-creatinine ratio (UPCR) at Week 26 compared to baseline. About EMPAVELI®/Aspaveli® (pegcetacoplan)EMPAVELI®/Aspaveli® (pegcetacoplan) is a targeted C3 therapy designed to regulate excessive activation of the complement cascade, part of the body's immune system, which can lead to the onset and progression of many serious diseases. It is approved for the treatment of C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN) in the United States and paroxysmal nocturnal hemoglobinuria (PNH) in the United States, European Union, and other countries globally. The therapy is also under investigation for other rare diseases. U.S. Important Safety Information for EMPAVELI BOXED WARNING: SERIOUS INFECTIONS CAUSED BY ENCAPSULATED BACTERIA EMPAVELI, a complement inhibitor, increases the risk of serious infections, especially those caused by encapsulated bacteria, such as , , and type B. Life-threatening and fatal infections with encapsulated bacteria have occurred in patients treated with complement inhibitors. These infections may become rapidly life-threatening or fatal if not recognized and treated early. Complete or update vaccination for encapsulated bacteria at least 2 weeks prior to the first dose of EMPAVELI, unless the risks of delaying therapy with EMPAVELI outweigh the risks of developing a serious infection. Comply with the most current Advisory Committee on Immunization Practices (ACIP) recommendations for vaccinations against encapsulated bacteria in patients receiving a complement inhibitor. Patients receiving EMPAVELI are at increased risk for invasive disease caused by encapsulated bacteria, even if they develop antibodies following vaccination. Monitor patients for early signs and symptoms of serious infections and evaluate immediately if infection is suspected. Because of the risk of serious infections caused by encapsulated bacteria, EMPAVELI is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the EMPAVELI REMS. CONTRAINDICATIONS Hypersensitivity to pegcetacoplan or to any of the excipients For initiation in patients with unresolved serious infection caused by encapsulated bacteria including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type B WARNINGS AND PRECAUTIONS Serious Infections Caused by Encapsulated Bacteria EMPAVELI, a complement inhibitor, increases a patient's susceptibility to serious, life-threatening, or fatal infections caused by encapsulated bacteria including Streptococcus pneumoniae, Neisseria meningitidis (caused by any serogroup, including non-groupable strains), and Haemophilus influenzae type B. Life-threatening and fatal infections with encapsulated bacteria have occurred in both vaccinated and unvaccinated patients treated with complement inhibitors. The initiation of EMPAVELI treatment is contraindicated in patients with unresolved serious infection caused by encapsulated bacteria. Complete or update vaccination against encapsulated bacteria at least 2 weeks prior to administration of the first dose of EMPAVELI, according to the most current ACIP recommendations for patients receiving a complement inhibitor. Revaccinate patients in accordance with ACIP recommendations considering the duration of therapy with EMPAVELI. Note that ACIP recommends an administration schedule in patients receiving complement inhibitors that differs from the administration schedule in the vaccine prescribing information. If urgent EMPAVELI therapy is indicated in a patient who is not up to date with vaccines against encapsulated bacteria according to ACIP recommendations, provide the patient with antibacterial drug prophylaxis and administer these vaccines as soon as possible. The benefits and risks of treatment with EMPAVELI, as well as the benefits and risks of antibacterial drug prophylaxis in unvaccinated or vaccinated patients, must be considered against the known risks for serious infections caused by encapsulated bacteria. Vaccination does not eliminate the risk of serious encapsulated bacterial infections, despite development of antibodies following vaccination. Closely monitor patients for early signs and symptoms of serious infection and evaluate patients immediately if an infection is suspected. Inform patients of these signs and symptoms and instruct patients to seek immediate medical care if these signs and symptoms occur. Promptly treat known infections. Serious infection may become rapidly life-threatening or fatal if not recognized and treated early. Consider interruption of EMPAVELI in patients who are undergoing treatment for serious infections. EMPAVELI is available only through a restricted program under a REMS. EMPAVELI REMS EMPAVELI is available only through a restricted program under a REMS called EMPAVELI REMS, because of the risk of serious infections caused by encapsulated bacteria. Notable requirements of the EMPAVELI REMS include the following: Under the EMPAVELI REMS, prescribers must enroll in the program. Prescribers must counsel patients about the risks, signs, and symptoms of serious infections caused by encapsulated bacteria, provide patients with the REMS educational materials, ensure patients are vaccinated against encapsulated bacteria at least 2 weeks prior to the first dose of EMPAVELI, prescribe antibacterial drug prophylaxis if patients' vaccine status is not up to date and treatment must be started urgently, and provide instructions to always carry the Patient Safety Card both during treatment, as well as for 2 months following last dose of EMPAVELI. Pharmacies that dispense EMPAVELI must be certified in the EMPAVELI REMS and must verify prescribers are certified. Further information is available at or 1-888-343-7073. Infusion-Related Reactions Systemic hypersensitivity reactions (eg, facial swelling, rash, urticaria, pyrexia) have occurred in patients treated with EMPAVELI, which may resolve after treatment with antihistamines. Cases of anaphylaxis leading to treatment discontinuation have been reported. If a severe hypersensitivity reaction (including anaphylaxis) occurs, discontinue EMPAVELI infusion immediately, institute appropriate treatment, per standard of care, and monitor until signs and symptoms are resolved. Interference with Laboratory Tests There may be interference between silica reagents in coagulation panels and EMPAVELI that results in artificially prolonged activated partial thromboplastin time (aPTT); therefore, avoid the use of silica reagents in coagulation panels. ADVERSE REACTIONS Most common adverse reactions in adult and pediatric patients 12 years of age and older with C3G or primary IC-MPGN (incidence ≥10%) were infusion-site reactions, pyrexia, nasopharyngitis, influenza, cough, and nausea. USE IN SPECIFIC POPULATIONS Females of Reproductive Potential EMPAVELI may cause embryo-fetal harm when administered to pregnant women. Pregnancy testing is recommended for females of reproductive potential prior to treatment with EMPAVELI. Advise female patients of reproductive potential to use effective contraception during treatment with EMPAVELI and for 40 days after the last dose. Please see full , including Boxed WARNING regarding serious infections caused by encapsulated bacteria, and . About Apellis Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company leading the way in complement science to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two C3-targeting medicines approved to treat four serious diseases. Breakthroughs for patients include the first-ever therapy for geographic atrophy, a leading cause of blindness, and the first treatment for patients 12 and older with C3G or primary IC-MPGN, two severe, rare kidney diseases. We believe we have only begun to unlock the potential of targeting C3 across many serious diseases. For more information, please visit or follow us on LinkedIn and X. Apellis Forward-Looking Statement Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute 'forward-looking statements' within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements regarding the potential market opportunity of EMPAVELI for C3G and IC-MPGN. The words 'anticipate,' 'believe,' 'continue,' 'could,' 'estimate,' 'expect,' 'intend,' 'may,' 'plan,' 'potential,' 'predict,' 'project,' 'should,' 'target,' 'will,' 'would' and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including whether the clinical trial results of EMPAVELI for C3G and IC-MPGN indicate an effect that is greater than the actual positive effect; and any other factors discussed in the 'Risk Factors' section of Apellis' Annual Report on Form 10-K with the Securities and Exchange Commission on February 28, 2025 and the risks described in other filings that Apellis may make with the Securities and Exchange Commission. Any forward-looking statements contained in this press release speak only as of the date hereof, and Apellis specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise. Media:Tracy Vineismedia@ Investors: Neil Carnahan, References1. Data on file using literature consensus. 2. Smith RJH, et al. Nat Rev Nephrol. 2019;15(3):129-143.3. Servais A, et al. Kidney Int. 2012;82(4):454-464.4. Zand L, et al. J Am Soc Nephrol. 2014;25(5):1110-1117.5. Tarragón, B, et al. C3 Glomerulopathy Recurs Early after Kidney Transplantation in Serial Biopsies Performed within the First 2 Years after Transplantation. Clinical Journal of the American Society of Nephrology. August 2024; 19(8)1005-1015. doi: 10.2215/CJN.0000000000000474. A photo accompanying this announcement is available at
Yahoo
36 minutes ago
- Yahoo
Strength Building: How Strength Training Supplements Help You Build Muscle Mass and Keep Growing Stronger
CrazyBulk New York City, NY, July 28, 2025 (GLOBE NEWSWIRE) -- Build muscle mass and keep growing stronger with CrazyBulk's legal strength training supplements. Explore the best stacks for real power gains in 2025In the evolving world of performance fitness, strength building isn't just about lifting heavier—it's about training smarter, fueling properly, and choosing science-backed supplements that support sustainable muscle growth. As more athletes, fitness enthusiasts, and bodybuilders shift away from synthetic enhancers, a natural powerhouse is gaining serious ground: CrazyBulk strength training for individuals serious about improving performance and sculpting lean muscle mass, CrazyBulk's product lineup has become a go-to solution for building muscle mass and growing stronger—without resorting to illegal or dangerous alternatives. With a clean, gym-tested reputation and a growing global following, CrazyBulk is helping redefine how men and women approach strength building in you're pushing through plateaus or just starting your resistance journey, the right supplements can dramatically influence your training outcomes. CrazyBulk combines clinically supported ingredients with carefully tailored formulas to assist with muscle recovery, testosterone support, endurance, and explosive strength—the core pillars of functional this exclusive report, we dive into what makes CrazyBulk stand out, explore how its strength training supplements impact real results, and examine why fitness coaches and athletes across the country are backing its mission. If you're ready to build muscle mass, break personal records, and keep growing stronger—this is the stack you need to know about. Why Strength Building Needs a Smarter Supplement Strategy in 2025 In 2025, strength building is no longer a one-dimensional pursuit of heavy lifting and high-protein meals. Today's athletes, bodybuilders, and fitness-focused individuals understand that true muscular growth and peak performance require more than raw effort. It's about optimizing recovery, supporting hormonal health, and giving your muscles the right fuel to rebuild and grow. That's where a smarter supplement strategy comes in—and why CrazyBulk has become a trusted name in modern strength training. The era of shortcuts and synthetic boosters is fading. With increased scrutiny around banned substances and long-term health risks, fitness-conscious consumers are now prioritizing clean, legal supplements that deliver consistent results without compromising safety. CrazyBulk fits directly into this shift, offering science-based alternatives that mimic the effects of traditional anabolics—minus the side effects or legal concerns. What makes the strategy 'smarter' is its synergy. CrazyBulk's strength stack doesn't just target one mechanism—it works on multiple fronts: promoting testosterone production, boosting nitric oxide levels, increasing muscular endurance, and reducing post-workout fatigue. This multi-layered approach ensures your body stays in an optimal anabolic state, allowing you to lift heavier, recover faster, and grow stronger consistently. For anyone serious about building strength in today's fitness climate, a random pill or powder isn't enough. You need targeted support from trusted, gym-tested formulations. In 2025, strength building belongs to those who train with strategy—and supplement with intention. View official website for latest best pricing and promotions Inside the Formula: What Makes CrazyBulk Supplements Work When it comes to building muscle mass and boosting raw strength, not all supplements are created equal. In fact, most fall short where it matters: ingredient transparency, proven effectiveness, and long-term safety. That's where CrazyBulk has distinguished itself in the strength training market—by engineering formulas backed by science, built for performance, and trusted by serious lifters product in CrazyBulk's strength stack targets a specific physiological mechanism essential for growth. For example, D-BAL uses a potent blend of MSM, ashwagandha, and L-leucine to mimic the muscle-building effects of Dianabol—without the harsh side effects. It supports protein synthesis, reduces muscle soreness, and promotes faster recovery after intense lifting there's Testo-Max, CrazyBulk's natural testosterone amplifier, which uses ingredients like D-aspartic acid, zinc, and ginseng to support healthy T-levels—critical for explosive strength, stamina, and drive. These hormonal boosts play a central role in lifting heavier, training longer, and staying anabolic throughout your bulking sets CrazyBulk apart is the synergy across its products. Instead of isolated effects, their stack creates a compound performance boost—targeting recovery, endurance, power output, and lean muscle growth all at once. Plus, each product is manufactured in FDA-inspected facilities using clinically dosed ingredients, ensuring clean labeling and strict short, CrazyBulk isn't just another supplement line—it's a precision-engineered system for growing stronger, naturally and legally. For athletes serious about results, what's inside the formula makes all the Strength Building Supplements for Fast Results— Visit official CrazyBulk website Growing Stronger Naturally: Avoiding Banned Substances In today's competitive fitness environment, the push for strength often comes with a dangerous temptation: synthetic performance enhancers. From anabolic steroids to banned SARMs, the risks tied to these substances are well-documented—ranging from hormonal imbalances to long-term organ damage. That's why a growing wave of athletes in 2025 are shifting their focus to natural, legal alternatives that support muscle growth without putting their health or careers in strength training supplements have become the leading choice for lifters looking to grow stronger without crossing regulatory lines. Each formula is designed to mimic the muscle-building effects of traditional steroids, using clean, plant-based and lab-supported ingredients instead of risky synthetics. The result? Legitimate strength gains without the legal grey areas or side effect profiles associated with black-market CrazyBulk products are 100% legal in the USA, contain no banned substances, and are manufactured in GMP-certified facilities. Athletes don't have to worry about failing drug tests or compromising their reputations. Instead, they get to train hard, recover faster, and build muscle with peace of natural approach also means CrazyBulk is ideal for long-term use. Unlike harsh cycles that can damage your endocrine system or liver, CrazyBulk stacks are formulated for sustainable performance—allowing users to keep growing stronger month after a world where strength is often pursued at any cost, CrazyBulk is proving that real results can come from smart choices, not Stack is Right for Your Strength Goals? Strength Stack: Build Muscle Mass & Raw Power the Natural Way For lifters focused on increasing raw strength and muscle density without turning to banned substances, CrazyBulk's Strength Stack delivers a powerful, legal solution. Designed for those chasing heavier lifts, stronger core movements, and improved athletic output, this four-product combo is specifically formulated to help users build muscle mass and grow stronger stack includes D-BAL, Testo-Max, DecaDuro, and Tren-Max—each targeting a critical element of performance: protein synthesis, testosterone support, nitrogen retention, and muscular endurance. Together, they work to reduce recovery time, increase training volume, and push users through strength traditional steroids that carry harsh side effects, the Strength Stack is made with natural ingredients that support clean gains, hormone balance, and better joint recovery. This makes it a perfect choice for athletes, gym-goers, and powerlifters who want real strength improvements without compromising health or consistently, the stack can enhance core compound lifts like squats, bench presses, and deadlifts, making it easier to track progress and hit new PRs. Many lifters report noticeable improvements in stamina and post-workout recovery within just 2–3 you're ready to train harder, lift heavier, and recover faster—without needles or prescriptions—the CrazyBulk Strength Stack is your foundation for next-level power. Available exclusively from the official CrazyBulk website, it's the go-to option for strength training in 2025. Unlock explosive strength gains—get the CrazyBulk Strength Stack now from the official website Growth Hormone Stack: Unlock Maximum Muscle Growth Potential For those pushing beyond average gains, the CrazyBulk Growth Hormone Stack is engineered for elite-level performance and muscle development. This powerful five-product combo includes HGH-X2, D-BAL, Clenbutrol, Testo-Max, and DecaDuro—each targeting a different aspect of hypertrophy and stack centers around HGH-X2, CrazyBulk's growth hormone releaser, which helps stimulate the body's natural production of human growth hormone. When paired with the muscle-boosting properties of D-BAL and Testo-Max, and the fat-burning action of Clenbutrol, this stack becomes a comprehensive system for those aiming to build muscle mass, enhance recovery, and stay lean during growth phases. Athletes using this stack report enhanced muscle tone, faster post-workout repair, and better pumps during training. It's ideal for intermediate to advanced lifters looking to take their physique to the next level—without synthetic injections or hormone therapy. The Growth Hormone Stack supports performance in high-intensity environments by improving muscle density, blood flow, and metabolism simultaneously. And because all ingredients are 100% legal and natural, users avoid the downsides of hormonal manipulation or banned substances. For bodybuilders and hard-gainers alike, this stack unlocks new levels of muscular potential. If your goal is to maximize lean size without compromising definition, CrazyBulk's Growth Hormone Stack is your go-to solution in 2025. Boost reps, power, and recovery—get CrazyBulk Growth Stack only at the official website Cutting Stack: Preserve Strength While Shedding Fat Strength doesn't have to fade during a cutting phase. The CrazyBulk Cutting Stack is formulated for athletes and lifters who want to maintain power and preserve muscle mass while losing body fat. It's a smart, clean-cut combo featuring Clenbutrol, Testo-Max, Anvarol, and Winsol—each tailored to help users achieve a leaner, harder physique without sacrificing calorie deficits, muscle loss can be a major risk. This stack is built to counter that, with Anvarol and Win-Max promoting lean retention and vascular muscle tone, while Clenbutrol ramps up thermogenesis and metabolic speed. Testo-Max, included in all CrazyBulk stacks, keeps testosterone levels optimized, which is essential for strength, mood, and energy while cutting. What makes this stack stand out is its ability to balance fat loss with performance. Whether you're prepping for summer, a physique competition, or just dialing in your look, the Cutting Stack ensures you hold onto the muscle you worked hard to build. Results can typically be seen in as little as 2–4 weeks, especially when paired with a clean diet and resistance training program. Most users report feeling stronger and more defined—without the flat, drained look that often comes with extreme dieting. If you're looking to burn fat while keeping your strength intact, the CrazyBulk Cutting Stack offers the definition without the compromise. Available only on the official site, it's 2025's top stack for strategic shredding. Train harder, recover faster—visit the official CrazyBulk site to get the Cutting Stack Bulking Stack: Power Through Mass Building Phases When it's time to bulk, your body needs more than just calories—it needs anabolic support, endurance-enhancing compounds, and hormone balance to grow efficiently. That's where the CrazyBulk Bulking Stack comes in. Designed for the classic mass-building phase, this four-product powerhouse includes D-BAL, Testo-Max, DecaDuro, and Trenorol—each with a specific role in increasing size, recovery, and workout intensity.D-BAL leads the charge, mimicking the muscle-building effects of Dianabol, while Deca-Max supports joint function and strength. Tren-Max enhances vascularity and muscle conditioning, and Testo-Max ensures your testosterone remains in the optimal range to support explosive growth. Unlike dirty bulks that result in excess fat gain, the Bulking Stack is engineered to support lean muscle gains, minimize bloating, and reduce the 'bulk crash' once the phase ends. It's the ideal choice for lifters who want visible gains in size, strength, and gym performance—without compromising definition or well-being. Used over an 8-week cycle, most users experience noticeable improvements in muscle fullness, power output, and energy. Plus, the clean-label ingredients make this stack suitable for long-term programs. If you're planning a growth phase or need to add real size without fluff, the CrazyBulk Bulking Stack delivers results that fuel your offseason goals. It's the serious stack for serious gains—backed by real lifters across the globe. Build real muscle mass and Grow Stronger—Visit the official CrazyBulk Bulking Stack today Ultimate Stack: All-in-One Strength, Size & Definition Solution If you want everything in one, the CrazyBulk Ultimate Stack is your complete muscle-building and performance system. Featuring six powerhouse supplements—D-BAL, Testo-Max, DecaDuro, Trenorol, Clenbutrol, and Anadrole—this is the most comprehensive stack in the CrazyBulk lineup, built for advanced users who want to push every you're bulking, cutting, or recompositioning, this stack offers full-cycle support. D-BAL and Anadrole fuel massive pumps and rapid growth. Clenbutrol and Tren-max help manage body fat while sharpening vascularity. Testo-Max and Deca-max ensure testosterone and joint function stay strong throughout intense training blocks. The Ultimate Stack is ideal for competitors, transformation challengers, or dedicated gym-goers looking for a total physique overhaul. It helps users build muscle mass, maintain power during cuts, and recover faster between sessions—all while staying 100% legal and natural. Most athletes report dramatic improvements in strength, muscularity, and workout intensity within the first month. It's not for casual users—it's for those committed to the grind and ready for elite results. If you're serious about making 2025 your most transformative year yet, the CrazyBulk Ultimate Stack offers the tools, science, and synergy to help you dominate. No needles. No prescriptions. Just clean, compound results—available now on the official CrazyBulk website. Train harder, recover faster—visit the official CrazyBulk site to get the Ultimate Stack TREN-MAX - Safest Legal Supplement for Muscle Mass CrazyBulk's TREN-MAX is a highly effective supplement that closely emulates the anabolic properties of Trenbolone, a widely utilized steroid for promoting muscle growth and mass. It has been a prominent choice amongst bodybuilders for TREN-MAX is an effective and safe muscle-building supplement that is formulated from 100% natural ingredients. It promotes the development of lean muscle mass while also aiding in the reduction of excess fat for a well-defined physique. TREN-MAX is a legal dietary supplement by CrazyBulk that is intended to replicate the muscle-building benefits of the potent anabolic steroid Trenbolone Acetate. TREN-MAX by CrazyBulk is a completely natural supplement that provides significant muscle growth without any chemical stress on the body, unlike Trenbolone Acetate is widely recognized as a highly hazardous anabolic steroid due to its toxicity level. In stark contrast, TREN-MAX is capable of delivering all the benefits of Trenbolone while bypassing the accompanying adverse effects. Visit CrazyBulk Official Website For TREN-MAX Ingredients TREN-MAX's carefully curated formula generates musculature that is both solid, resilient, and devoid of excess fat. This is the reason why it is highly sought after by individuals engaged in bodybuilding, as well as others. It additionally endeavors to enhance the body's metabolic efficiency while facilitating a substantial reduction in adipose tissue. This effect is attributed to the presence of beta-sitosterol, a plant-derived sterol with documented ability to facilitate weight loss and promote fat metabolism. According to clinical research, it has been demonstrated that this product can effectively enhance weight loss outcomes by as much as 6.3% while also reducing body fat levels by up to 3%. Furthermore, TREN-MAX guarantees enhanced hygiene as an inevitable benefit. Beta-sitosterol is an active ingredient known for enhancing vascularity in addition to its potential fat-burning and ribbing benefits. When used in conjunction with Samento Inner Bark, a scientifically validated substance known for its ability to enhance nitric oxide production within the body, the product can produce remarkable results for your physical well-being. The production of nitric oxide facilitates heightened circulation, resulting in greater delivery of vital oxygen and nutrients to the compromised musculature. Ultimately, the distinct formula of CrazyBulk's TREN-MAX is capable of significantly minimizing the buildup of lactic acid in muscular tissues, thereby mitigating muscle soreness and promoting a more efficient post-workout recovery. Beta Sitosterol Uncaria Tomentosa Nettle plant Pepsin Acquire CrazyBulk TREN-MAX at the current market rate. TREN-MAX can be procured exclusively through the authorized platform of TREN-MAX is priced at USD 64.99 per bottle and provides a 30-day supply to consumers. Where to Buy CrazyBulk's Legal Strength Stack Safely With demand for natural strength training supplements at an all-time high, it's crucial to know where to buy CrazyBulk products safely and directly—without risking counterfeits, inflated prices, or expired stock. In 2025, the only trusted source for authentic CrazyBulk stacks is the official CrazyBulk directly from the manufacturer guarantees several key benefits. First, you'll receive genuine, factory-sealed products made in FDA-inspected, cGMP-certified facilities—ensuring purity, consistency, and full ingredient transparency. Second, the site offers exclusive multi-buy deals, fast shipping across the USA, and periodic promotions that aren't available through third-party retailers or shady online importantly, ordering from the official site ensures your purchase is covered by CrazyBulk's risk-free 60-day money-back guarantee. If you don't see improvements in your strength, stamina, or muscle tone, you can request a full refund—no questions asked. That level of customer protection reflects CrazyBulk's confidence in the results their products the CrazyBulk Strength Stack—which includes D-BAL, Testo-Max, DecaDuro, and Trenorol—is the most recommended combo for serious lifters. Each stack is designed to work synergistically, helping users build muscle mass, recover faster, and grow stronger across all phases of avoid imitations or expired knock-offs, fitness experts strongly advise skipping unauthorized eCommerce platforms or overseas suppliers. For guaranteed results and secure checkout, visit the official CrazyBulk website and explore your strength-building options today. Final Take: The Future of Strength Training Starts Here Strength training has entered a new era—one that prioritizes clean supplementation, long-term health, and performance without compromise. As lifters move away from synthetic shortcuts and banned substances, the focus is now on sustainable strength, backed by smart science and legal support. At the center of this shift is CrazyBulk, a brand that's redefining how athletes build muscle mass and keep growing stronger— success of CrazyBulk's strength training supplements isn't just hype. It's built on a foundation of formulated synergy, clinically-supported ingredients, and results-driven design. Users aren't just lifting heavier—they're seeing faster recovery, enhanced muscle volume, and better hormonal balance, all without the risks typically associated with performance sets CrazyBulk apart in 2025 is its commitment to natural strength progression. Whether you're an amateur looking to improve gym performance or a seasoned athlete chasing new personal records, CrazyBulk provides the legal tools to get you there—with no injections, no prescriptions, and no fear of you're tired of empty promises and underdosed formulas, it's time to upgrade your strategy. The future of strength building isn't found in dangerous cycles or underground labs—it's found in trusted, transparent supplementation that works with your body, not against Strength Stack is more than a trend—it's a movement. And for those serious about pushing limits and unlocking peak performance, the time to join that movement is now. For more information, educational content, and direct purchasing, visit the official Crazybulk website. Company Name: Crazybulk244 Madison Avenue,New York City, NY 10016-2817Postal code: NY 10016-2817Media Contact:Full Name - Neil BowersEmail: support@ 888-708-6394Company website: The statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult a healthcare professional before taking any dietary All trademarks, registered trademarks, product names, and logos mentioned herein are the property of their respective owners. References to specific products, brands, companies, or organizations are for identification purposes only and do not constitute an endorsement unless explicitly stated. This article may be syndicated or republished by third-party publishers, blogs, or platforms. In such cases, the republishing party assumes full responsibility for maintaining the accuracy and compliance of the published version. The original publisher, its writers, editors, or sponsors shall not be held liable for any misuse, misrepresentation, or misinterpretation of the information contained LinkWorkout Routine For MenAttachment CrazyBulk CONTACT: Company Name: Crazybulk 244 Madison Avenue, New York City, NY 10016-2817 Postal code: NY 10016-2817 Media Contact: Full Name - Neil Bowers Email: support@ +1 888-708-6394 Company website: in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
41 minutes ago
- Yahoo
Are melatonin supplements safe for kids?
The first time your baby sleeps through the night seems unforgettable — like a hopeful promise of a more rested future — but as many parents (unfortunately) find out, that hope often ends up feeling more like a mirage. Sleep challenges are a common part of parenting, and they can look different from household to household — or even night to night. Whether your child struggles to fall asleep or stay asleep, you're not alone. And if you've ever found yourself searching "natural sleep aids for kids" at 1 a.m., chances are melatonin has popped up. Yet despite this supplement's growing popularity, you may be wondering whether melatonin supplements are actually safe for kids. Melatonin is a hormone that helps regulate the body's internal clock, and while it's often used by adults to help manage sleep disorders and insomnia, over-the-counter melatonin supplements have become increasingly popular for kids too. Whether it's due to travel challenges and disrupted schedules, insomnia or sleep difficulties linked to ADHD or autism, parents are increasingly interested in using melatonin supplements as a way to help their kids (and themselves) get much-needed rest. To help cut through the confusion — and save you another sleepless nighttime scroll — we spoke with three pediatric experts, including two doctors and a registered dietitian, about if and when melatonin might be helpful and what to know about dosing and safety before purchasing a supplement. A note on supplements The products included on this list are dietary supplements. Statements about these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Dietary supplements are not appropriate for everyone and may interact with other supplements or medications, so talk to your health care provider before adding a dietary supplement to your routine. Are melatonin supplements safe for children? The short answer is yes, though Dr. Michelle Caraballo, sleep medicine specialist at Children's Health, and Dr. Rupali Drewek, co-medical director of the Sleep Medicine Program at Phoenix Children's, agree that these products aren't appropriate or effective for all kids and should be used only short-term under medical supervision. "Melatonin is usually recommended for short-term use (typically two to six weeks) while behavioral interventions are established. If effective, it can be used intermittently as needed, but long-term daily use should be monitored by a health care provider," says Drewek. She also notes that because melatonin isn't habit-forming, it doesn't require tapering off. "That said, if a child has been using it regularly for months, slowly reducing the dose over one to two weeks can help [you] evaluate whether it's still necessary. Some families find when you gradually taper off from melatonin, it avoids abrupt changes in sleep quality. It's also a good time to reinforce consistent bedtime routines and healthy sleep habits," she says. As for who might benefit, research is ongoing but has mostly looked at the benefits (and safety) of melatonin for kids with certain conditions. "It can be helpful for specific conditions such as delayed sleep-wake phase disorder or sleep issues in children with autism or ADHD. However, it is not FDA-approved for pediatric use, and safety data for long-term use is limited," Drewek says. She also cautions that because dietary supplements aren't tested for label accuracy by the Food and Drug Administration (FDA), quality and dosing can vary greatly between products. What about toddlers? From transitioning out of the crib to starting nighttime potty training, sleep becomes a particularly tricky issue with toddlers. However, Caraballo cautions that these supplements should not be given to children under the age of 3. There simply isn't enough research to determine whether melatonin is safe or appropriate for 1- and 2-year-olds. How much melatonin is safe for kids? How much melatonin to give your child should ultimately be decided by your pediatrician. Here's a general idea of what dosing might look like, according to Drewek: Preschoolers (3–4 years): 1 mg School-age children (5–12 years): 1–3 mg Adolescents (13–18 years): up to 5 mg Keep in mind that your pediatrician may recommend different doses than what's listed above, or encourage starting with a lower dose and gradually increasing. "We ask parents to start with a low dosage, according to age, and carefully evaluate how effective it is. Many children respond to a low dose (1–5 milligrams) when taken 30 minutes before bedtime," says Caraballo. Drewek echoes the importance of starting low and slow, adding, "Higher doses don't always improve sleep and may increase side effects like morning grogginess or vivid dreams." Other factors to consider when choosing a melatonin supplement for kids Once you have the green light from your pediatrician to give your child a bedtime supplement, the next step is choosing a product. As with any supplement, there are a few key factors to keep in mind when making your decision: Age-appropriate dose: To provide a safe and effective dose, only give your child a melatonin supplement that's specifically formulated for their age. Supplement type: Melatonin supplements for kids come in a variety of types, including gummies, liquids, powders, chewables and dissolvable tablets. There are also soft gel options for adolescents. The best option is the one that your child can take safely, though some forms may be more readily absorbed than others. "We generally recommend liquid or oral dissolvable formulation over gummies because the absorption is more reliable with liquid and tablet forms," says Caraballo. Other active ingredients: Some kids' bedtime supplements include other ingredients, like magnesium or L-theanine. While safe for kids, it's best to talk with your pediatrician about whether these ingredients are necessary or appropriate for your child. Sweeteners and food dyes: Some brands add sweeteners and food dyes — natural or artificial — to make supplements more appealing to kids. Ideally, choose options with minimal added sugar and naturally derived flavors and colors, like those from fruit or vegetable juices and extracts. Third-party testing: "Several studies have shown that the amount of melatonin in a bottle can vary significantly from the amount listed on a label," says Caraballo. For this reason, it's important to choose a product made by a reputable brand that's ideally been tested for label accuracy by a trusted independent organization, like NSF or United States Pharmacopeia (USP). Potential side effects and safety concerns We probably sound like a broken record at this point, but research on melatonin in kids is limited, meaning there's still more that researchers and medical experts have to learn when it comes to safety. That said, short-term use of melatonin has not been linked with serious side effects in kids when taken in appropriate amounts. A 2024 review study published in the journal Children found that commonly reported side effects of melatonin supplements in kids include vivid dreams, nightmares and extreme tiredness. Still, this doesn't mean there aren't serious safety concerns. "Supplements should be treated like medications. It is important to discuss with your child's physician before starting a supplement, as some supplements can interact with other medications and may not be appropriate for all children. And just like medications, supplements should be stored in a locked cabinet out of the reach of children," says Caraballo. "Accidental ingestion of melatonin by children has led to a significant increase in ER visits in recent years, so proper storage is critical," adds Drewek. If you're concerned that your child consumed excessive amounts, call your pediatrician or another medical professional right away. Alternatives to melatonin "To help your child sleep well, the most important thing you can do is establish a bedtime routine — and be consistent. Maintain the same bedtime and wake time every day, including weekends and holidays. Kids really respond well to routine, so that their bodies know what to expect," says Caraballo. If your child is struggling to fall or stay asleep, start by checking their sleep environment. "Keep bedrooms cool, dark and quiet. Darkness cues the brain that it's time to sleep. A dim nightlight is fine for children who may not like total darkness," says Caraballo. Bedtime routines should also evolve as kids grow, notes Drewek. For toddlers and preschoolers, predictable steps like brushing teeth, reading and cuddling can create a sense of security. School-age kids benefit from screen-free wind-down time and consistent sleep schedules. And while teens may be harder to guide, encouraging them to leave phones outside the bedroom can help curb late-night scrolling. If the thermostat is set, screens are off, the sound machine is humming and your child's bedtime routine is solid — yet sleep is still a struggle — it might be time to consider other natural sleep aids for kids. Several companies offer melatonin-free supplements featuring ingredients like magnesium or L-theanine. "These ingredients may help promote relaxation and ease bedtime anxiety, especially in children who are sensitive to melatonin or don't tolerate it well. While they don't directly shift the circadian rhythm like melatonin, they can be useful for calming the nervous system," says Drewek. Just note that while these supplements may be more appropriate for long-term use — as long as you have the OK from your pediatrician — Caraballo recommends melatonin more often than other supplements because it "has better data supporting its use in children." Melatonin supplements for kids As a registered dietitian and mom of two, I know firsthand how challenging it can be to navigate the world of kids' supplements. To help, I reviewed 10 of the top melatonin products for kids, evaluating each on dose, ingredients and kid-friendly factors, like taste and texture. Here are three standout options to talk with your pediatrician about. FAQs Can a 3-year-old take melatonin? Yes, according to Caballo, melatonin can be given to a 3-year-old, though it's important to do so only under the recommendation of a pediatrician. How often can you give melatonin to a child? According to Drewek, melatonin supplements are typically recommended for just two to six weeks while other behavioral and bedtime strategies are established. That said, how frequently to give your child melatonin for sleep may vary and should be discussed with a pediatrician. Drewek also notes that while melatonin may be a useful tool for some kids, it doesn't replace the need for a consistent bedtime routine. "Sleep supplements should never replace healthy sleep habits, which are the foundation of good sleep," she says. Is melatonin addictive for kids? No, according to Caraballo, "[Melatonin] is not considered addictive, and discontinuation should not cause withdrawal symptoms." However, due to a lack of research on its safety and effectiveness, melatonin shouldn't be given to your child for more than a few weeks or months. Instead, it's important to work with a health care professional to identify the root cause of your child's sleep disturbances. What's a safe melatonin brand for children? There are several reputable brands offering melatonin supplements for kids, including OLLY, Natrol, Zarbee's, Mommy's Bliss and more. Look for products that are tested to ensure label accuracy, ideally by a third-party lab. Can diet affect kids' sleep? According to Katie Drakeford, board-certified pediatric registered dietitian, yes, your child's diet could be contributing to their sleep troubles. In particular, Drakeford notes that diets low in omega-3 fatty acids and vitamin D may negatively affect your child's sleep, though research on the benefits of supplementation is limited. Overall, no single food is likely to make or break your child's sleep quality. To support better rest, studies (like this 2023 review published in the journal Nutrients) suggest prioritizing a diet rich in fiber — especially fruits and vegetables — while limiting foods high in saturated fat. Meet our experts Michelle Caraballo, MD, pediatric pulmonologist and sleep medicine specialist at Children's Health Rupali Drewek, MD, co-medical director of the Sleep Medicine Program at Phoenix Children's Katie Drakeford, board-certified pediatric registered dietitian Our health content is for informational purposes only and is not intended as professional medical advice. Consult a medical professional on questions about your health.
