
Want better health, less anxiety, more sleep? You've got a nerve
Who's acquainted with their vagus nerve? If you're on Instagram or TikTok, you'll know that you need to 'reset' the thing to soothe your nervous system and reduce anxiety, and that investing in 'vagus massage oil' or a vibrating bracelet or pressing an ice pack to your chest will do it. All your ills will be cured. Allegedly.
'The vagus nerve [the longest cranial nerve in the body] is one of the most popular nerves in social media today,' the neurosurgeon Kevin Tracey declares. And it deserves to be celebrated. 'Resting and digesting and keeping calm all depend on your vagus nerve, which is the linchpin of the parasympathetic nervous system,' he says.
Tracey is the professor and president of Northwell Health's Feinstein Institutes for
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'Systolic blood pressure and mean arterial pressure are important indicators of how hard the heart is working to circulate blood,' Hackman explained. 'Even small reductions in these measures can lower the risk of heart disease and stroke over time. So seeing a noticeable drop shortly after eating mangoes, as well as sustained improvements with daily intake, is a promising sign that eating mango daily may help support cardiovascular health in a meaningful way.' 2 weeks of daily mangoes 'Total cholesterol and LDL are key markers linked to heart disease risk. Lowering these levels, even modestly, can have a positive long-term impact on cardiovascular health. The fact that we saw these changes after just two weeks of daily mango consumption suggests it could be a simple, food-based approach to help support better cholesterol management, especially in postmenopausal women.' — Roberta Holt, PhD Researchers also conducted a follow-up study with six participants who were asked to consume about 1.5 cups of mangoes on one lab visit, and about 3 oz of plain white bread on a subsequent visit. Scientists observed that while participants' blood sugar levels rose after eating both foods, it increased significantly less after eating mangoes compared to white bread. Additionally, study participants' insulin levels peaked and declined quickly after eating mango, but remained elevated two hours after eating white bread. 'That finding highlights how not all carbohydrates affect the body the same way. While both mango and white bread contain carbohydrates, mango (leads) to a smaller rise in blood sugar and a quicker return to normal levels,' Holt said. 'That's important because large or prolonged spikes in blood sugar can increase the risk of insulin resistance and other metabolic issues over time. Mangoes, with their fiber and bioactive compounds, may help blunt that response, making them a viable choice for blood sugar management,' he added. MNT had the opportunity to speak with Adedapo Iluyomade, MD, a cardiologist with Miami Cardiac & Vascular Institute, part of Baptist Health South Florida, about this study. 'I was pleasantly surprised that a simple whole-food swap nudged both systolic blood pressure and LDL cholesterol downward in just two weeks — results we usually struggle to achieve without medication,' Iluyomade commented. 'At the same time, the serving size (about two mangoes a day) and the small, generally healthy sample mark this as encouraging but not yet practice-changing.' 'Cardiometabolic risk climbs steeply after menopause, yet women remain under-represented in nutrition trials,' he continued. 'Food-based strategies that are easy to adopt can fill the gap between lifestyle advice and pharmacotherapy, giving patients more autonomy and allowing clinicians to personalize care rather than rely on data largely derived from men.' Just mangoes or other fruits, too? 'A longer, randomized study using a realistic one-cup daily serving — and a matched control fruit — would clarify whether the benefits persist and are mango-specific. Adding ambulatory blood-pressure monitoring, insulin sensitivity testing, and gut microbiome profiling in a larger, more diverse cohort would help pin down mechanisms and real-world relevance.' — Adedapo Iluyomade, MD MNT asked Monique Richard, MS, RDN, LDN, a registered dietitian nutritionist and owner of Nutrition-In-Sight, for her top tips on how readers can incorporate more mangoes into their diet. The 'king' of fruits 'Mangoes, known as the 'king of fruits' in India, are rich sources of nutrients that support immune and heart health such potassium, magnesium, and vitamins A, B6, folate, C, and E, as well as phytochemicals such as mangiferin, anthocyanins, gallic acid, and kaempferol to name a few. Some studies have suggested that these phytochemicals are cardio-protective against inflammation, oxidative stress, and support blood vessel health, as well as digestive health from the fiber and natural enzymes.' — Monique Richard, MS, RDN, LDN For readers interested in trying to incorporate mangoes more often into their diet, Richard suggested a few easy ways: Adding to salads — fruit, greens, or even pasta salads Add to smoothies Puree into salad dressings and marinades, or freeze into Popsicle-like frozen treats or gelato Add to, or substitute for, fruit in a variety of salsa, chutney, and relish recipes Top yogurt, cottage cheese, or ricotta toast Mix with mint or basil to top baked or grilled tilapia, salmon, or flounder Peel and enjoy with a handful of nuts and seeds for a healthy snack Small, peeled portions can be dropped into your juicer to add refreshing sweetness to your favorite vegetable juices Enjoy it by itself as a healthy addition to a balanced breakfast, lunch, or dinner 'Add mangoes to the list of versatile fruits and vegetables that are nutritious, delicious and advantageous to your heart health, and enjoy!,' Richard added.