White Sox at Astros prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 10
Its Tuesday, June 10 and the White Sox (22-44) are in Houston to begin a three-game series against the Astros (36-29).
Shane Smith is slated to take the mound for Chicago against Lance McCullers for Houston.
Each of these clubs was off on Monday. The White Sox flew in from Chicago following a seven-game homestand that saw the Sox split four games with the AL Central division-leading Tigers and take two of three from the Royals. Houston lost Sunday, 4-2, to Cleveland but took the first two games of their series against the Guardians.
Lets dive into the series opener and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Game details & how to watch White Sox at Astros
Date: Tuesday, June 10, 2025
Time: 8:10PM EST
Site: Minute Maid Park
City: Houston, TX
Network/Streaming: CHSN, SCHN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the White Sox at the Astros
The latest odds as of Tuesday:
Moneyline: White Sox (+165), Astros (-198)
Spread: Astros -1.5
Total: 8.0 runs
Probable starting pitchers for White Sox at Astros
Pitching matchup for June 10, 2025: Shane Smith vs. Lance McCullers
White Sox: Shane Smith (2-3, 2.46 ERA)
Last outing: 5.1IP, 0ER, 3H, 2BB, 6KsAstros: Lance McCullers (1-1, 4.44 ERA)
Last outing: 6IP, 0ER, 2H, 1BB, 7Ks
White Sox: Shane Smith (2-3, 2.46 ERA)
Last outing: 5.1IP, 0ER, 3H, 2BB, 6Ks
Astros: Lance McCullers (1-1, 4.44 ERA)
Last outing: 6IP, 0ER, 2H, 1BB, 7Ks
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of White Sox at Astros
Jeremy Pena saw his 13-game hitting streak snapped Sunday
Lance McCullers has 27Ks in his last 3GP (16.1IP)
The Astros have covered in 4 straight games with Lance McCullers starting
Miguel Vargas is 2-14 (.143) in his last 5 games
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the White Sox and the Astros
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Tuesday's game between the White Sox and the Astros:
Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
Total: NBC Sports Bet is staying away from a play on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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Jay Croucher (@croucherJD)
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