Corcept says Catalyst trial met primary endpoint
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Business Wire
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Catalyst OrthoScience Announces Full Commercial Release of Fracture Shoulder System
NAPLES, Fla.--(BUSINESS WIRE)-- Catalyst OrthoScience Inc. ('Catalyst'), a private medical technology leader focused on shoulder arthroplasty, the fastest growing segment in the orthopedics market, announced today the full commercial release of the Catalyst Fracture Shoulder System. While this marks the latest innovation in Catalyst's expanding portfolio, the company continues to expand its momentum within the orthopedic community – underscored by recently published midterm data from its Catalyst CSR™, which demonstrates industry-leading Single-Assessment Numeric Evaluation (SANE) scores. At Catalyst, we're not bound by convention – we're defining what comes next. Our technology is designed to solve real shoulder arthroplasty challenges and we're committed to helping shoulder surgeons achieve better results with less complexity. Share 'At Catalyst, we're not bound by convention – we're defining what comes next,' said Carl O'Connell, president and chief executive officer of Catalyst. 'Our technology is designed to solve real shoulder arthroplasty challenges, and our clinical outcomes prove the value of that approach. We're committed to helping shoulder surgeons achieve better results with less complexity.' This release continues to expand Catalyst's differentiated portfolio, bringing a fracture-specific solution that prioritizes tuberosity fixation and healing—key factors consistently shown to produce better outcomes. Designed to improve reverse shoulder arthroplasty for proximal humeral fractures (PHFs), the system includes patented technology that helps reduce surgical complexity and drive clinical confidence. Entering a fracture market estimated at over $250 million, Catalyst is seeing strong early adoption and is positioned to capture significant market share. The news comes on the heels of its recent announcement of 5-8 year published midterm data supporting its Catalyst CSR™ Total Shoulder System - the first product Catalyst launched to the market. Catalyst continues to provide solutions that enable surgeons to deliver outcomes that outpace traditional total shoulder arthroplasty (TSA) solutions and this independent study introduced a new industry benchmark, showing that: Patients who underwent anatomic total shoulder arthroplasty (aTSA) with the Catalyst CSR system experienced exceptionally high patient satisfaction, little to no pain, significant functional improvements, and very low revision rates that are well below the average data published for similar aTSA implants. These clinical results highlight Catalyst's focus on anatomic precision and reproducible solutions that eliminate unnecessary complexity while enabling optimized outcomes. 'The data speaks volumes, but so does the growing enthusiasm we're seeing from the orthopedic community,' said Dr. Theodore Blaine, orthopedic surgeon. 'Catalyst has earned a reputation for smart shoulder arthroplasty solutions that align with how surgeons work and the results they expect – whether in hospitals or ASCs – and that's what makes it different.' Catalyst's commitment to surgeon engagement is just as strong as its product portfolio and pipeline. In addition to growing interest and presence at major orthopedic meetings, the company is strengthening its partnership with the American Shoulder and Elbow Surgeons (ASES) through sponsorship of the 2025 ASES Annual Meeting and the 2026 ASES Mentor & Mentee Meeting. These events provide a meaningful platform to connect with established thought leaders and rising surgical talent—reinforcing Catalyst's role as a company that listens, evolves, and leads and is the go-to partner for surgeons who demand better. This forward momentum underscores the company's focus – sustainable growth, surgeon-first mindset, and unmatched value for healthcare systems – which continues to resonate with the orthopedic community. Catalyst OrthoScience, based in Naples, Florida, is redefining shoulder replacement surgery. With a focus on less invasive techniques, fewer complications, and a more natural-feeling shoulder, Catalyst is breaking away from traditional approaches. Our total shoulder systems are engineered for precision and efficiency – preserving bone and soft tissue while enabling delivery of consistent, reproducible results. With a growing portfolio of issued and pending patents, Catalyst technology is available across the U.S. Learn more at and connect with us on LinkedIn.
Yahoo
5 days ago
- Yahoo
Scientists stumble upon game-changing 'triple efficiency' in pursuit of powerful fuel: 'We plan to move forward'
Scientists stumble upon game-changing 'triple efficiency' in pursuit of powerful fuel: 'We plan to move forward' A team of researchers in South Korea may have just reshaped the future of green fuel. While developing a cleaner, more efficient way to produce ammonia, which is a compound that is widely used in fertilizers and looked at as a next-generation fuel, they stumbled upon a catalyst that delivers three times the output of the previous methods. The new catalyst, made of ruthenium (Ru) nanoparticles, was designed to increase efficiency in ammonia synthesis under milder conditions. According to a study reported by Tech Xplore, it achieved what researchers called "triple efficiency," which could slash pollution output and reduce the high energy costs that are associated with ammonia production. The increase in efficiency solves the issue of ammonia made at a global scale, mainly through the Haber-Bosch process, which requires an intense amount of heat and pressure. That method is responsible for nearly 1.3% of global planet-warming pollution like CO2, as per the International Energy Agency. The newly developed catalyst works at lower temperatures and pressures, which would cut down on both pollution and production costs. The study mentions that the structure of the catalyst is what makes the key difference. Researchers used a polyol-based method to expose more "B5-sites", a type of atomic configuration on the catalyst surface that boosts activity. The sites allow nitrogen and hydrogen to bond more easily and form ammonia and improve the overall efficiency. "We plan to move forward with performance verification through mass production of pellet-type catalysts and application in various ammonia cracking systems," study author Dr. Jeong Woo Han said in the Tech Xplore report. If scaled up, this could help industries reduce their carbon footprint while also enabling clean hydrogen transport. Since ammonia can store and move hydrogen, it's seen as a promising energy carrier in an economy that no longer relies on carbon pollution. While there is no set rollout timeline, the researchers believe their method can be adopted using existing infrastructure, which could help speed things up. Should the U.S. be investing more in battery production to catch up with China? Absolutely We're investing a good amount We should be investing less I have no idea Click your choice to see results and speak your mind. Join our free newsletter for weekly updates on the latest innovations improving our lives and shaping our future, and don't miss this cool list of easy ways to help yourself while helping the planet. Solve the daily Crossword
Business Wire
6 days ago
- Business Wire
CATalyst Council Launches Landmark 40,000 Household Pet Ownership Study Focused on Advancing Feline Health
ANNAPOLIS, Md.--(BUSINESS WIRE)--In celebration of International Cat Day celebrated annually on August 8th, CATalyst Council announces the next phase of its ongoing commitment to advancing the feline veterinary market, closing the feline care gap, and reshaping the future of cat-centered care across the animal health ecosystem: a nationwide, 40,000-household survey study. The study is designed to generate a high confidence understanding of the emotional, behavioral, and psychological factors influencing veterinary care decisions, and to identify actionable insights that can drive innovation, increase feline medicalization, and improve health outcomes for cats. "This study will arm the industry with the data to bend the curve by taking real, measurable steps toward solving the feline care gap." -Jon Ayers, CATalyst Council, Feline Market Insights Committee Chair Share Designed by CATalyst with support of key industry association collaborators and two leading animal health market research firms, Forward Group and Kynetec, this initiative is one of the most comprehensive studies of U.S. household pet ownership ever undertaken, and the largest in the last five years. This primary consumer research builds on the momentum of the CATalyst Council's quarterly Feline Market Insights Reports, a series of analyses launched in early 2025 to track feline and overall visit trends and drivers, demographic shifts, and caregiver mindsets. 'The quarterly market insight reports reveal critical trends in veterinary health and also help us frame the questions of pet owners,' said Jon Ayers, CATalyst Council board member and chair of its Market Insights Committee. 'Now we will have it straight from the pet owner. The survey results will also give the industry and profession the most definitive view of pet ownership in the US, including the demographic age profile for both cats and dogs. This knowledge of pet demographics is destiny: the age profiles help predict future veterinarian visit growth. We will also come to understand vet visit behavior by pet and owner demographic. And thus, this study will arm the industry with the data to bend the curve by taking real, measurable steps toward solving the feline care gap." 'This is about listening to the households that shape our profession's future,' said Dr. Anne Ward, Chair of CATalyst Council. 'To be truly cat friendly every day, we must understand the human behaviors, perceptions, and emotional motivators that surround feline care, and we're doing it at a scale that's never been done before.' 'For too long, we've made assumptions about why cats don't get the care they need,' said Dr. Jane Brunt, Executive Director of CATalyst Council. 'This consumer research replaces assumptions with evidence, so we can build better solutions for cats, their people, and the professionals who care for them.' 'CATalyst is grateful for the technical support and advice we are receiving from our industry and association collaborators, including FelineVMA, AVMA, and APPA, as well as our leading industry sponsors,' said Brunt. While this landmark survey will also capture dog ownership and veterinary visit behaviors in order to establish key industry benchmarks, the core focus is on understanding the full spectrum of behaviors, beliefs, and barriers among cat-owning households nationwide. A Strategic Roadmap: From Market Signals to Measurable Change Building on the foundation laid by CATalyst Council's Feline Market Insights Reports, the survey will deepen understanding of what motivates or prevents cat owners from seeking care, how generational mindsets shape veterinary decisions, and what emerging patterns can guide future innovation across veterinary medicine, the animal health industry, and aligned pet care brands. Research Objectives Aligned with CATalyst Council's mission to improve the lives of cats and their people through innovation, education, and appropriate medicalization, the study aims to: Provide an updated and statistically robust estimate of cat and dog populations in U.S. households, and by year of age Reveal emotional, psychological, and behavioral drivers of veterinary visit behavior and avoidance Identify motivators that can increase feline medicalization, especially in multi-pet households Inform the development of tools, education, and strategies to support industry-wide progress Designed for Impact, Built for the Entire Ecosystem This research is structured to deliver value across the feline care ecosystem: Cat Owners & Caregivers: Insights into how and why caregivers seek (or delay) veterinary care Veterinary Teams: Actionable findings to support client communication, adherence, and visit growth Animal Health and Pet Care Companies: Data to support product innovation, education programs, and marketing strategy Investors: Clear visibility into the drivers behind veterinary visits, trends, as well as emerging opportunities in the growing market for feline veterinary care Initial findings will begin rolling out in Q4 2025, with detailed insights shared exclusively with our CATalyst sponsors and strategic partners. The study, along with CATalyst's quarterly reports, will empower industry and veterinary professionals to pilot targeted programs and measure impact based on validated feline and caregiver needs, ensuring the industry stays informed, aligned, and equipped to act. 'As we honor International Cat Day, we're focused not just on celebrating cats, but on understanding them, supporting their people, and building the systems that can serve them both better,' said Kristin Wuhrman, Vice Chair of the CATalyst Council. 'This is much more than the research. It's infrastructure for the future of feline care.' To receive updates or inquire about the benefits of sponsorship, please visit and follow CATalyst Council on LinkedIn. About CATalyst Council CATalyst Council is a national organization dedicated to accelerating innovation in feline care and enhancing quality of life for cats and their people. CATalyst Council's vision is to ensure all companion cats receive lifelong care by using evidence-based resources, embracing community-wide relationships for optimal health outcomes, and celebrating the human-feline bond.
