The simple skin solution everyone is talking about: Here's what to know
Forget fillers and frozen expressions—today's skincare revolution is all about regeneration from within. One of the most talked-about breakthroughs in this space is Polydeoxyribonucleotide (PDRN), a salmon-DNA-derived compound making waves through its natural, skin-reviving powers. In an exclusive chat with India Today, leading aesthetic dermatologist Dr. Amit Bhasin of Prive Clinic, Gurgaon, breaks down why PDRN is fast becoming a favourite for patients and practitioners alike.advertisement'In over 400 cases at my clinic, I've seen PDRN consistently deliver rejuvenation results that are safe, effective, and natural-looking,' says Dr. Bhasin.WHAT IS PDRN, AND HOW DOES IT WORK?PDRN is a low-molecular-weight DNA polymer extracted from salmon trout (Oncorhynchus mykiss), with proven effects on tissue repair, inflammation control, and collagen regeneration.
Its primary mechanism works through the activation of A2A adenosine receptors, which:Promote angiogenesis (blood vessel formation)Stimulate fibroblast proliferationAccelerate tissue healing and skin remodelingWHY PATIENTS ARE CHOOSING PDRN OVER FILLERS'Increasingly, patients are hesitant about neurotoxins and heavy fillers,' notes Dr. Bhasin. 'They want fresher, younger skin without frozen expressions. PDRN gives them exactly that—hydration, glow, and texture improvement—without altering their natural look.'According to him, nearly 95% of patients report visible skin improvement, and satisfaction levels are notably high.advertisementPeriorbital RejuvenationDark circles, puffiness, and under-eye pigmentation respond remarkably well to PDRN through improved microcirculation, collagen stimulation, and inflammatory control.Wrinkle ReductionPDRN improves elasticity, smooths fine lines, and firms skin by regenerating the extracellular matrix and enhancing collagen and elastin synthesis.Superior Skin HydrationPatients report a lasting glow and smoother texture. The treatment boosts hyaluronic acid production and strengthens the epidermal barrier.Pore Size ReductionBy balancing sebum production and improving dermal structure, PDRN helps shrink enlarged pores and refine skin texture.Acne and Post-Acne ScarringPDRN supports faster healing, reduces pigmentation, and prevents acne scarring through fibroblast activation and cytokine regulation.Non-Healing WoundsFor patients with ulcers or chronic wounds, especially when paired with PRP or PRF, PDRN accelerates re-epithelialization and healing.Powerful Combinations: PDRN Plus Other Aesthetic TherapiesDr. Bhasin emphasises that PDRN works even better in synergy with various popular treatments:PRP / PRF: Enhanced tissue repair and anti-inflammationClearLift Laser: Better collagen remodeling and pigmentation controlMicroneedling (PCIT): Improved product penetration and collagen inductionHIFU: Faster recovery and deeper tissue regenerationSkin Boosters / Baby Botox: A glowing finish with no volume overloadPDRN also integrates well withCO2 & Er:YAG LasersMNRFIPL, LED light therapyadvertisementDermal FillersChemical PeelsOxygen & MesotherapyTHE INDIAN SKIN ADVANTAGEDr. Bhasin believes PDRN is particularly suited to Indian skin types, which are prone to pigmentation, inflammation, and acne-related scarring.'It's gentle, adaptable, and works across all ages. Whether it's glow enhancement for brides, anti-aging for professionals, or acne repair for teens—PDRN fits right in,' he explains.Polydeoxyribonucleotide isn't just a trend—it's a cornerstone in the evolving field of skin regeneration. With science-backed mechanisms, high patient safety, and visible aesthetic outcomes, PDRN is closing the gap between cosmetic desire and dermatological healing.Dr. Amit Bhasin's clinical experience with PDRN is a compelling testimony to its future potential—not only as an anti-aging tool but also as a holistic skin-healing therapy.'We're entering the age of skin intelligence—treatments that work with your biology, not against it,' he concludes.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
India.com
3 hours ago
- India.com
Meet Indian genius who scored 720/720 in NEET-UG, cracked IIT-JEE with 99.9 percentile, studied only 4 hours a day with no fixed routine, he is...
Meet Indian genius who scored 720/720 in NEET-UG, cracked IIT-JEE with 99.9 percentile, studied only 4 hours a day with no fixed routine, he is... Getting into the Indian Institutes of Technology (IITs) is a dream for many students in India. The entrance exams, JEE Main and JEE Advanced are among the toughest in the world. At the same time, the National Eligibility cum Entrance Test (NEET) is the main path to becoming a doctor in India. While most students focus on just one of these, Mrinal Kutteri managed to clear both. Mrinal comes from Hyderabad and lives with his parents, younger brother, and grandparents. His family originally hails from Kerala, and interestingly, no one in his close family is a doctor but his interest in science began early. In classes 8 and 9, he started enjoying biology and chemistry. By the time he entered class 11, he had set his goal to prepare for NEET. In a 2021 interview with India Today , Mrinal shared that he first thought about becoming an army doctor because he wanted to combine medicine and adventure. However, over time, his focus shifted more toward the medical field alone. He also said that seeing doctors fight the COVID-19 pandemic inspired him even more to choose this path. How Mrinal Kutteri balanced studies during the pandemic When the COVID-19 pandemic forced schools to shut down, students across the country had to switch from classroom learning to online classes. This sudden change affected many, but Mrinal Kutteri welcomed it at first. Mrinal shared that in the beginning, he actually enjoyed the lockdown. However, this shift soon affected his academic performance, and he realized he needed to get back on track. Though it took some time at the beginning, he eventually got into a better routine. Interestingly, Mrinal didn't follow a strict study timetable like many other toppers. He admitted that he liked a flexible approach to learning. According to him, trying to stick to a tough schedule that he couldn't follow would only lead to stress and waste time. Instead, he chose to study in a way that suited him best, based on his energy and interest levels each day. Mrinal Kutteri's study approach that led to NEET AIR 1 In a 2021 interview with India Today , NEET topper Mrinal Kutteri shared how he followed a unique and stress-free way of studying. Instead of having a strict daily timetable, he chose a flexible method. Each day, he would set a small goal for himself, and how he completed it was entirely up to him. 'There were many days when I couldn't complete what I planned,' Mrinal admitted, 'but I didn't feel discouraged. I was okay with that, and I think that really helped me stay calm and focused.' His study routine changed often. Some days, he was very productive, while on others, he found it hard to study at all. On average, Mrinal studied for about four hours a day, and on his best days, he went up to five hours, but never more than that. Contrary to the notion that students must sacrifice hobbies during intense exam preparation, Mrinal ensured a balance between academics and leisure. He enjoyed binge-watching comedy shows on Netflix and Prime, using entertainment as a means of relaxation and motivation. Even for other tough exams like KVPY and JEE Main in Class 12, he didn't put in extra hours beyond his NEET prep. Still, he managed to score an amazing 99.9 percentile in JEE Main. But his biggest success came with NEET 2021, where he achieved a perfect score of 720 out of 720, securing All India Rank 1.
India Today
16 hours ago
- India Today
Early paediatric surgery offers hope for birth defects with timely diagnosis and treatment
Birth defects can be overwhelming for families, but medical advances in pediatric surgery now offer hope—and often, a complete recovery. Early intervention is key, and many congenital issues can be treated effectively, allowing children to live healthy, normal understand how these surgical corrections impact long-term health and development, India Today spoke with Dr Koushik Herle, Paediatric and Neonatal Surgeon at Manipal Hospital, Sarjapur, who highlighted the importance of timely diagnosis, specialist care, and early SURGICAL CONDITIONS WITH EXCELLENT OUTCOMESInguinal Hernias A frequent issue in infants and young children, inguinal hernias occur when abdominal tissue pushes into the groin. 'It's a straightforward outpatient surgery,' explains Dr Herle. 'Quick correction prevents complications like bowel obstruction, and children recover rapidly with no long-term effects.'Undescended Testes (Cryptorchidism)In boys, failure of one or both testes to descend into the scrotum requires a minor surgery called orchidopexy, ideally performed between 6 and 12 months of age. 'This early correction ensures proper development and supports future fertility,' says Dr Junction Obstruction (PUJO) & HydronephrosisThis obstruction blocks urine flow from the kidney, causing swelling. If untreated, it may harm kidney function. 'Pyeloplasty, usually done in infancy, has a 90–95% success rate and preserves kidney health,' shares Dr Reflux (VUR)VUR is the backward flow of urine from the bladder to the kidneys, leading to infections and potential damage. 'Mild cases may resolve on their own, but severe forms benefit from surgical correction, with success rates above 95%,' says Dr SURGICAL EMERGENCIES – EARLY ACTION SAVES LIVESadvertisementTracheoesophageal Fistula (TEF) and Esophageal AtresiaThese conditions prevent safe feeding due to abnormal connections between the esophagus and windpipe. 'Prompt surgery within the first days of life is often lifesaving,' explains Dr Herle. 'Over 90% of cases can be successfully treated at experienced centers.'Intestinal Atresias (Bowel Obstructions)When a newborn's intestine is blocked, surgery must be performed immediately. 'It's a critical emergency, but once treated, the baby can resume normal digestion and growth,' notes Dr ANOMALIES – TREATING STRAWBERRY MARKS EARLYInfantile HemangiomasOften called 'strawberry marks,' these benign tumors are usually harmless and fade over time. However, those located near the eyes, lips, or airway—or those that ulcerate—require intervention.'Propranolol, a beta-blocker, has revolutionised treatment,' Dr Herle explains. 'If started early—within the first few weeks or months—it can stop the haemangioma from growing, accelerate its regression, and avoid permanent scarring.'He emphasises the need for early referral: 'Parents should consult a paediatric surgeon or vascular anomaly specialist to ensure optimal cosmetic and medical outcomes.'COMPLEX CONDITIONS THAT REQUIRE SPECIALISED CAREAnorectal Malformations and Bladder ExstrophySome congenital anomalies, such as an abnormally developed rectum or bladder located outside the body, require staged reconstructive surgeries.'These procedures can be extensive,' says Dr Herle, 'but they allow children to achieve good function and lead full lives. Importantly, most of these children have normal intelligence and can go to school, pursue careers, and thrive socially.'WHY A PEDIATRIC SURGEON MAKES ALL THE DIFFERENCEadvertisementPediatric surgeons are specially trained to manage surgical conditions in infants, children, and adolescents. Their expertise includes:Child-Specific Knowledge: Children are not just small adults. Their physiology, healing, and conditions are Techniques: From minimally invasive surgeries to delicate neonatal procedures, pediatric surgeons tailor every approach to the child's developing Care: Pediatric surgical teams often include neonatologists, anesthesiologists, and pediatric nurses for holistic care.'Obstetricians and pediatricians play a vital role by referring cases early,' Dr Herle emphasises. 'The sooner a child is evaluated, the better their chances for a full recovery.'EMPOWERING PARENTS WITH KNOWLEDGE AND HOPEWith advances in surgical techniques and neonatal care, many birth defects are now treatable, sometimes with a single operation. Others, while more complex, are manageable with proper planning and Dr Herle concludes, 'Timely surgery can transform a child's life. Early diagnosis, early referral, and a pediatric surgical specialist can make all the difference for the child and the family. advertisement
India Today
18 hours ago
- India Today
How sleep tech is transforming rest and wellness across India
Technology has revolutionised nearly every facet of modern life — from ergonomic seating that supports posture during long office hours to customised skincare targeting specific skin concerns. Amongst these lifestyle upgrades, one area gaining remarkable momentum is sleep — a pillar of health that remains underappreciated yet a country like India, where stress levels are soaring and sleep deprivation is becoming a silent epidemic, tech-driven solutions could be the answer to better rest and long-term wellness. India Today spoke with Mr Ganesh Sonawane, Co-founder and CEO at Frido, to understand how this rapidly evolving domain is reshaping the way Indians TECH: A PARADIGM SHIFT IN REST AND RECOVERYSleep tech refers to the ecosystem of gadgets and innovations designed to enhance sleep quality using intelligent systems. Gone are the days of just a comfy mattress or a white noise machine. Today's sleep technology employs AI, smart sensors, and machine learning to monitor, analyse, and improve sleep. 'Sleep tech is not about comfort alone any more. "It's about measurable health outcomes,' said Mr Sonawane. 'From heart rate to snoring patterns, technology is now helping decode sleep on a much deeper level.'SMART PILLOWS: FROM HEADRESTS TO HEALTH MONITORSOnce a basic bedroom accessory, the pillow has turned into a smart sleep companion. Smart pillows now offer adjustable firmness, ergonomic shaping, and integrated biometric sensors. These innovations cater to various sleep positions and spinal health, while also tracking movement, snoring, and even REM of these pillows also feature temperature-regulating technology, maintaining optimal coolness or warmth depending on user preference. Some AI-enabled models also detect snoring and subtly reposition the user's head to alleviate obstruction, offering relief for both the sleeper and their and mattresses are also undergoing a high-tech transformation. Today's smart beds incorporate pressure-sensitive support systems that adapt in real-time to your body. Some even allow couples to customise each side of the mattress based on their individual comfort needs."One big barrier in India is price," said Mr Sonawane. "We noticed that people continue using old mattresses, unaware of the long-term harm they cause. That's where solutions like mattress toppers — a simple, tech-enabled upgrade — are gaining traction.'These toppers offer temperature regulation and orthopaedic support without the need to purchase a new mattress — a game-changer in price-sensitive markets like TECH AND ITS DIRECT IMPACT ON HEALTHThe importance of sleep extends far beyond rest. Sleep tech devices actively combat insomnia, sleep apnea, and chronic fatigue. By using biofeedback and real-time analysis, they promote better sleep hygiene and mental backs this up. Studies show that employees who nap or sleep better experience higher productivity and income gains. Additionally, managing sleep apnea — a condition that affects a growing number of Indians — can drastically reduce risks of hypertension and Type 2 underestimate how much poor sleep contributes to poor immunity, obesity, and even mood disorders. Sleep tech is a proactive way to reverse that,' Mr Sonawane LIES AHEAD: THE FUTURE OF SLEEP TECH IN INDIAThe next frontier for sleep tech lies in personalised AI-powered sleep plans. Innovations will soon allow for smart lighting, tailored soundscapes, and neurofeedback-based interventions that stimulate deeper, restorative sleep is also catching up fast. As digital awareness increases and more urban dwellers prioritise wellness, the adoption of sleep tech is expected to surge.'Technology is evolving to not only track your sleep but guide you toward healthier rest patterns,' said Mr Sonawane. 'From smart pillows that detect breathing irregularities to cooling mattresses that adjust to summer nights, the future is about sleeping smarter — no longer.'In an age of information overload and endless hustle, sleep has emerged as a silent casualty. But thanks to technological innovation, it is also becoming the gateway to better health, productivity, and India begins to recognise the long-term value of sleep, the integration of smart sleep solutions into everyday life will only grow. And as Mr Sonawane concluded: 'Investing in how we sleep is investing in how we live.' advertisement
