The Top 5 Analyst Questions From Moderna's Q1 Earnings Call
Is now the time to buy MRNA? Find out in our full research report (it's free).
Revenue: $108 million vs analyst estimates of $117.9 million (35.3% year-on-year decline, 8.4% miss)
Adjusted EPS: -$2.52 vs analyst estimates of -$3.11 (18.9% beat)
The company reconfirmed its revenue guidance for the full year of $2 billion at the midpoint
Market Capitalization: $10.39 billion
While we enjoy listening to the management's commentary, our favorite part of earnings calls are the analyst questions. Those are unscripted and can often highlight topics that management teams would rather avoid or topics where the answer is complicated. Here is what has caught our attention.
Salveen Richter (Goldman Sachs) pressed for detail on the FDA's requirement for additional flu vaccine efficacy data and its impact on the timing for the flu/COVID combination, to which CEO Stephane Bancel explained the scientific rationale and anticipated review extension.
Jasmine (UBS, for Eliana Merle) sought clarity on whether Phase 3 data for individualized neoantigen therapy (INT) remains on track for 2026, and inquired about trial expansion plans. President Stephen Hoge reiterated timelines are event-driven but remain possible, with further updates pending.
Tyler Van Buren (TD Cowen) asked about the likelihood of approval for the next-generation COVID vaccine given recent regulatory leadership changes. Hoge responded that interactions with the FDA have been 'business as usual,' with no change in review process observed.
Courtney Breen (Bernstein) questioned the drivers and flexibility behind the expanded cost-cutting program. CFO Jamey Mock explained that cost reductions are largely tied to the winding down of large Phase 3 trials and ongoing process improvements, rather than specific revenue signals.
Gena Wang (Barclays) asked about U.S. COVID vaccine market share and future prospects, to which Mock replied that script data supports a stable market position and attributed lower reported revenue to customer inventory management rather than underlying loss of share.
Looking ahead, the StockStory team will closely monitor (1) regulatory decisions for Moderna's next-generation COVID, RSV, and flu vaccines, (2) the pace and impact of ongoing cost reduction efforts as major clinical trials wind down, and (3) progress in late-stage pipeline programs—especially new data readouts for oncology and non-respiratory vaccines. Execution on product launches and continued market expansion will be key indicators of strategic progress.
Moderna currently trades at $26.84, down from $28.58 just before the earnings. In the wake of this quarter, is it a buy or sell? The answer lies in our full research report (it's free).
Donald Trump's victory in the 2024 U.S. Presidential Election sent major indices to all-time highs, but stocks have retraced as investors debate the health of the economy and the potential impact of tariffs.
While this leaves much uncertainty around 2025, a few companies are poised for long-term gains regardless of the political or macroeconomic climate, like our Top 6 Stocks for this week. This is a curated list of our High Quality stocks that have generated a market-beating return of 183% over the last five years (as of March 31st 2025).
Stocks that made our list in 2020 include now familiar names such as Nvidia (+1,545% between March 2020 and March 2025) as well as under-the-radar businesses like the once-micro-cap company Kadant (+351% five-year return). Find your next big winner with StockStory today.
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