Joe Rogan, young men rave about these supplements. But do they reduce sperm count?
A growing number of men are using testosterone supplements in the hopes of enhancing their physical performance, unaware of the drug's impact on their fertility, and more public figures — from Joe Rogan to Dax Shepard — are making their use of supplements known. From 2016 to 2019, prescriptions for testosterone replacement therapy (TRT, or 'T') have increased by 20%. Dr. Masaya Jimbo, a urologist and male infertility specialist at Reproductive Medicine Associates Philadelphia, says more college students are coming into his practice seeking — or already taking — testosterone.
However, research shows up to 25% of men do not have their testosterone levels checked before starting therapy, and up to a third do not meet the criteria for testosterone deficiency. Jimbo warns that the desired benefits of TRT — such as increased sex drive and enhanced fitness — do not outweigh the damage TRT can have on men's fertility.
'There's a lot of men who are out there taking testosterone thinking that it's making them more virile, but in fact, the testosterone is telling their testicles to shut off,' says Dr. Neel Shah, the Chief Medical Officer at Maven Clinic, a virtual clinic for women's and family health. 'Within three to six months, they can go from producing normal amounts of sperm to producing none at all.'
The White House wants more babies. They're ignoring part of the problem − men
What is testosterone? Risks and benefits of testosterone replacement therapy
Testosterone is a hormone produced primarily in the testicles that helps maintain men's bone density, fat distribution, muscle strength and mass, facial and body hair, red blood cell production, sex drive and sperm production.
Testosterone levels generally peak during adolescence and young adulthood, and begin declining by approximately 1% per year after age 30 or 40. A blood test is used to diagnose a low testosterone level, and a doctor may recommend testosterone replacement therapy in the form of injections, pill, patches or gels, for men with conditions like hypogonadism (when low testosterone levels are due to a disease rather than normal aging).
Studies show that patients not meeting the diagnostic criteria for testosterone deficiency are still being prescribed testosterone therapy, often based on vague symptoms. Jimbo says that among his college-aged patients, some report getting testosterone supplements from their friends.
'There's a big community that thinks of testosterone as an important or beneficial, purely enhancing kind of treatment to do,' he says. He often sees patients that tell him, 'All my friends do it too.'
The risks of TRT can include worsening sleep apnea, acne or other skin reactions, stimulating the growth of existing prostate cancer, englarging breasts, limiting sperm production and causing the testicles to shrink, and stimulating too much red blood cell production, which contributes to the increased risk of forming a blood clot.
And, testosterone supplements aren't always delivering their advertised results. A 2019 study evaluated 50 'T booster' supplements for composition and product claims. 90% percent of supplements claimed to 'boost T,' 50% 'improve libido,' and 48% 'feel stronger.' However, only 24.8% of supplements had data to support these claims, and 10.1% contained active ingredients with data suggesting a negative effect on T levels.
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Testosterone therapy may lower men's sperm count
The pituitary gland (a part of your brain that controls hormone release) produces two hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH tells the testicles to make testosterone, and that testosterone works with FSH to produce sperm.
Testosterone supplements can have a 'quick and dramatic' impact on fertility, Jimbo says.
Once a person starts taking exogenous testosterone, the pituitary gland recognizes that it no longer needs to produce it on its own, which causes the testicles to shrink over time and can halt sperm production.
It typically takes 3-6 months for sperm production to resume, but individuals who have been on high-dose testosterone for longer periods will require longer to return to normal sperm production. It can take up to three years for sperm to recover, but in a small number of patients, sperm production never fully recovers.
Research shows that for heterosexual couples trying to conceive, when the cause of infertility can be attributed to a known factor, it's a roughly 50-50 split between male and female factors. The male partner was found to be solely responsible in about 20% of infertility cases, and a contributing factor in another 30-40% of all cases.
'Usually when people want to start having kids, they really want to start having kids,' Shah says. 'The difference of having to wait six months or 12 months can be really meaningful.'
More: Elon Musk, JD Vance and why 'pronatalism' is having a moment right now
Biohacking, masculinity misperceptions can harm fertility
Biohacking, which is the pursuit of accomplishing the "best possible results" from your body, even if it requires extreme measures, has exploded in the wellness industry.
'2025 is just a very different era in terms of being able to push a button and get a drug in general,' Shah says. Telehealth providers have streamlined the process of testosterone therapy prescriptions (among many other medications, like GLP-1s), and expanded the market for testosterone supplements.
'I think that there's a lot of testosterone use that's not measured, and it shows up again in the fertility clinic,' Shah says.
A 2025 report by Maven Clinic that surveyed over 500 men aged 25–49 found that among men currently trying to conceive, or planning to conceive in the future, over half (55%) would be motivated to make lifestyle changes if they felt confident the changes would help conceive a child.
'Anecdotally, the majority of people, once they see the line between testosterone and being able to have children, are very willing to make the changes they need to make to have a family,' Shah says.
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Atlantic
01-08-2025
- Atlantic
Nicotine Is in Unchartered Territory
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Yahoo
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New Study Reveals a Hidden Benefit of Weight Loss Drugs for Men
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Yahoo
27-07-2025
- Yahoo
Testosterone Booster for Muscle Gain: Men Opt for OTC Supplement Form Natural Testosterone Replacement Therapy (TRT) Treatment in 2025
TestoPrime New York City, NY, July 27, 2025 (GLOBE NEWSWIRE) -- A recent survey shows that TestoPrime is widely regarded by men as the and the top choice for muscle-building results in the United States. In 2025, the pursuit of muscle mass and optimal health continues to drive innovation in the supplement world. For decades, men wanting to boost muscle growth, energy, and performance have turned to testosterone replacement therapy (TRT) as a solution for declining male hormone levels. Traditionally, TRT meant doctor-prescribed injections, gels, or patches—methods that, while effective, come with drawbacks like cost, inconvenience, and potential side effects. Enter the new era: pill form testosterone booster supplements for TRT. Over-the-counter, non-prescription supplements offer safe, natural alternatives for men looking to enhance their testosterone and, with it, muscle gains, recovery, and vitality. At the forefront of this revolution is TestoPrime, a brand rapidly becoming synonymous with natural testosterone therapy and transformative article will explore the science behind testosterone and muscle mass, the shift toward oral supplements. Read why TestoPrime is emerging as the number one choice for natural TRT for men in 2025. The Role of Testosterone in Muscle Growth and Men's Health Why Testosterone Matters Testosterone is the primary male hormone, responsible not only for hormonal male health but also for a host of bodily functions vital to muscle mass, strength, mood, and energy. As men age—or due to lifestyle factors—testosterone levels can decline, leading to: Reduced muscle mass and strength Increased body fat Lower energy and motivation Decreased libido and performance Mood changes such as irritability or depression Slower recovery from workouts Testosterone and Muscle Mass: The Science Muscle tissue is highly responsive to testosterone. The hormone's anabolic effects promote: Protein synthesis: Boosting the rate at which muscle fibers repair and grow after exercise. Nitrogen retention: A key factor in muscle recovery and growth. Red blood cell production: Enhancing oxygen delivery to muscles during training. Fat distribution: Helping to maintain a leaner physique. Low testosterone levels make it harder to gain or even maintain muscle, no matter how hard you train. Introducing TestoPrime: The Leader in Pill Form TRT Testosterone treatmentRead why doctors and clinicians recommend TestoPrime for low testosterone levels About TestoPrime Testosterone Supplements TestoPrime is a breakthrough supplement specifically formulated to naturally elevate and optimize testosterone levels in men. Backed by clinical research, TestoPrime is designed for: Men experiencing age-related testosterone decline Athletes and bodybuilders wanting to build lean muscle mass and recovery Anyone looking to reclaim energy, focus, and vitality Since its launch, TestoPrime has garnered a loyal following and impressive results - making it the go-to testosterone supplement in 2025. TestoPrime's Formula: What's Inside and How It Works Powerful, Natural Ingredients TestoPrime's formula is built on 12 evidence-based ingredients, all chosen for their synergistic effects: D-Aspartic Acid (DAA) A natural amino acid that stimulates LH production, signaling the body to boost testosterone levels. Panax Ginseng A legendary adaptogen, ginseng helps combat stress and supports libido, stamina, and energy. Ashwagandha Extract Reduces cortisol, the stress hormone that can suppress testosterone; also supports muscle growth and fat loss. Fenugreek extract Shown in studies to naturally increase testosterone and support strength and libido. Green Tea Extract (with EGCG) Antioxidant-rich, it supports fat burning and overall health. Pomegranate Extract Boosts blood flow and supports cardiovascular health, benefiting workout performance. Vitamin D Essential for testosterone production; most men are deficient. Zinc A mineral crucial for hormone health and immune function. Vitamin B6, B5, Garlic Extract, Black Pepper Extract Support energy metabolism, absorption, and overall hormonal balance. How TestoPrime Works Stimulates natural testosterone production DAA and fenugreek help the body make more of its own testosterone. Reduces stress and cortisol Ashwagandha keeps stress in check, protecting testosterone levels. Enhances energy, focus, and stamina Ginseng, green tea, and B vitamins keep you sharp and motivated. Improves muscle recovery and fat loss By supporting hormonal balance, TestoPrime optimizes your body's ability to build muscle and burn fat. TestoPrime vs. Prescription TRT: A Side-by-Side Comparison Feature TestoPrime (Pill) Prescription TRT (Injections/Gels) Prescription required No Yes Accessibility Worldwide, online Limited to clinics, prescription only Method Daily oral supplement Injections, gels, patches Ingredients Natural plant extracts, vitamins, minerals Synthetic testosterone Risk of side effects Low Moderate to high Hormonal shutdown No Yes (suppresses natural production) Muscle gain/fat loss support Yes Yes Libido & mood Yes Yes Cost Affordable, no doctor fees High, recurring medical costs Suitable for all men Yes (adults, not for those with medical conditions) Only for those diagnosed with low T The Muscle-Building Benefits of TestoPrime 1. Accelerated Muscle Growth By naturally increasing testosterone, TestoPrime amplifies protein synthesis and nitrogen retention—critical processes for building and repairing muscle fibers after intense workouts. Users report faster gains in size and strength, especially when combined with resistance training. 2. Improved Strength and Performance Higher testosterone enhances red blood cell production, resulting in better oxygen delivery and endurance. TestoPrime users often notice more power and stamina in the gym, enabling progressive overload and continual improvement. 3. Faster Recovery TestoPrime's anti-inflammatory and adaptogenic ingredients (like ashwagandha and ginseng) help the body recover from strenuous exercise, reducing muscle soreness and downtime. 4. Fat Loss and Leaner Physique Increased testosterone shifts the body's metabolism toward burning fat for fuel, particularly visceral (belly) fat. Combined with the thermogenic properties of green tea and pomegranate, TestoPrime helps users shed unwanted fat while preserving hard-earned muscle. 5. Enhanced Motivation and Mental Clarity Many men experience 'brain fog' or lack of motivation when testosterone is low. TestoPrime's blend of vitamins, adaptogens, and antioxidants supports mental focus, drive, and mood. Real User Results: Transformations with TestoPrime Case Study 1: Mark, 37 – From Plateau to Progress 'After turning 35, I noticed my workouts weren't getting the same results. I felt sluggish and wasn't adding muscle like before. After 8 weeks on TestoPrime, my energy shot up, my bench press increased by 30 lbs, and I lost 10 pounds of fat. This is the boost I needed!' Case Study 2: David, 42 – Reclaiming Youthful Vitality 'I'd been on prescription TRT for a year but hated the injections and side effects. Switching to TestoPrime was a game changer. I sleep better, have more energy, and my wife noticed the difference too.' Case Study 3: Mike, 29 – Natural Gains for Bodybuilding 'I wanted to stay natural but maximize my muscle growth. TestoPrime fits perfectly with my training. More strength, better recovery, and I feel unstoppable in the gym.' The Science Behind TestoPrime: Evidence for Each Ingredient D-Aspartic Acid (DAA) Clinical studies have shown that DAA can increase luteinizing hormone (LH) and, consequently, testosterone production in healthy men. One notable study found a 42% increase in testosterone after just 12 days of supplementation. Ashwagandha Research demonstrates that ashwagandha supplementation can significantly reduce cortisol levels and boost testosterone, especially in stressed or active men. In one trial, men taking ashwagandha experienced greater muscle gains and fat loss compared to placebo. Fenugreek Fenugreek has been shown to improve both total and free testosterone levels while supporting strength and body composition in resistance-trained men. Panax Ginseng Ginseng is an adaptogen that not only combats stress but also supports libido, energy, and overall hormonal balance. Zinc and Vitamin D Both are essential nutrients for healthy testosterone production. Studies repeatedly show that deficiency in either leads to reduced hormone levels and impaired muscle growth. KW;, Om AS;Chung. 'Dietary Zinc Deficiency Alters 5 Alpha-Reduction and Aromatization of Testosterone and Androgen and Estrogen Receptors in Rat Liver.' The Journal of Nutrition, U.S. National Library of Medicine, TestoPrime in Muscle Building and Cutting Cycles Bulking: Building Mass with Elevated Testosterone During a bulking phase, the goal is to maximize muscle growth with a caloric surplus and heavy resistance training. Higher testosterone levels facilitate: Greater muscle protein synthesis Faster recovery between sessions Increased strength and power output Less fat gain relative to muscle mass TestoPrime's formula supports all these processes, making it ideal for natural bodybuilders and athletes seeking maximum gains without synthetic hormones. Cutting: Preserving Muscle While Burning Fat Cutting cycles focus on shedding fat while maintaining muscle. Testosterone is key here, as low levels can lead to muscle loss during calorie restriction. TestoPrime: Preserves lean mass by supporting testosterone and reducing cortisol Accelerates fat loss via metabolic and thermogenic ingredients Maintains energy and motivation during tough dieting phases How to Use TestoPrime for TRT Maximum Results Dosage and Timing Recommended dose: 4 capsules once daily, ideally in the morning before breakfast. Consistency: Take TestoPrime every day, even on rest days, for best results. Cycle length: TestoPrime can be used continuously, but many users follow cycles of 8–12 weeks on, followed by a short break. Stacking with Other Supplements TestoPrime pairs well with: Protein powders (for muscle repair) Creatine (for strength and power) BCAAs/EAA supplements (for recovery) Fat burners (during cutting, if needed) Diet and Training Bulking: Combine TestoPrime with a calorie surplus and heavy, compound lifts. Cutting: Use alongside a slight calorie deficit, with an emphasis on protein and resistance training to spare muscle. Is TestoPrime Safe? Side Effects and Precautions Safety Profile TestoPrime is formulated with natural, clinically tested ingredients and is generally very well tolerated. Most users report no side effects. Who Should Avoid TestoPrime? Women and minors: Not recommended. Men with medical conditions: Consult a doctor before use, especially those with hormone-sensitive conditions or on medication. Allergies: Check the ingredient list for potential allergens. No Hormonal Suppression Unlike prescription TRT, TestoPrime does not shut down your body's own testosterone production. In fact, it works by supporting your natural hormonal pathways. Frequently Asked Questions 1. Is TestoPrime a steroid? No. TestoPrime is a natural supplement, not a steroid or synthetic hormone. It works by supporting your body's own testosterone production. 2. How quickly will I see results? Most users begin to notice increased energy and motivation within 2–3 weeks. Muscle and strength gains typically become noticeable after 4–6 weeks. 3. Can TestoPrime replace prescription TRT? For men with clinical testosterone deficiency, medical TRT may still be necessary. However, for most men seeking to optimize natural levels, TestoPrime offers a safe, effective alternative. 4. Is it legal and safe for sports? Yes, TestoPrime contains no banned substances and is safe for competitive athletes. 5. Do I need to cycle TestoPrime? While it can be taken continuously, many users prefer to follow 8–12 week cycles with breaks. 6. Can older men use TestoPrime? Absolutely. In fact, older men with age-related testosterone decline stand to benefit the most. TestoPrime Reviews and Community Buzz: Why TestoPrime is #1 in 2025Growing Popularity With thousands of positive reviews worldwide, TestoPrime has become a staple testosterone supplement for men looking to reclaim their strength, energy, and physique. Social Proof Fitness forums: Users report dramatic improvements in muscle mass, recovery, and motivation. YouTube/Instagram: Influencers and trainers increasingly recommend TestoPrime for natural muscle building. Wellness blogs: Health experts highlight its science-backed formula and transparent labeling. Satisfaction Guarantee TestoPrime offers a lifetime money-back guarantee—a testament to its effectiveness and customer trust. Where to Buy TestoPrime: Ensuring Authenticity and Results To guarantee you're getting the genuine product, always buy directly from the official TestoPrime website. Benefits include: Fresh, authentic product direct from the manufacturer Bulk order discounts and free shipping Lifetime money-back guarantee 24/7 customer support and guidance Avoid third-party resellers to steer clear of counterfeits and ensure eligibility for the guarantee. Traditional TRT: The Challenges of Injections and Gels Prescription TRT: The Standard Approach For years, men diagnosed with low testosterone have relied on medical testosterone replacement therapy (TRT). This typically involves: Injections: The most common method, often administered weekly or bi-weekly. Topical gels or patches: Applied to the skin daily. Implants or pellets: Inserted under the skin for slow hormone release. Limitations and Drawbacks While prescription TRT can be life-changing for men with clinical deficiency, it's not without downsides: Invasive and inconvenient: Injections require regular doctor visits; gels and patches can be messy or cause skin irritation. Side effects: Risk of acne, hair loss, sleep apnea, increased red blood cell count, high blood pressure and testicular shrinkage. Cost: Ongoing medical appointments and prescription fees add up. Not accessible to all: Only available with a clinical diagnosis and prescription. The Shift in 2025: Why Men Are Turning to Pill Form Testosterone Replacement Therapy The Demand for Natural TRT Treatments In 2025, more men are looking for ways to safely and effectively boost testosterone without needles, doctors, or prescriptions. The new generation of pill form testosterone boosting supplements answers this demand, offering: Convenience: Easy, daily oral dosing. Natural ingredients: Plant extracts, vitamins, and minerals shown to support healthy testosterone levels naturally. No prescription required: Accessible to all adult men, worldwide. Safer profile: Lower risk of side effects compared to synthetic hormone replacement. Comprehensive benefits: Improved muscle mass, energy, mood, and overall wellness. The Science Behind Natural Testosterone Boosters Pill-based supplements work by supporting the body's own testosterone production, rather than replacing it with synthetic hormones. Ingredients are chosen for their ability to: Stimulate luteinizing hormone (LH), signaling the testes to produce more testosterone Reduce stress hormones like cortisol, which can suppress testosterone Improve blood flow and nutrient delivery to muscles Support overall hormonal balance Treat erectile dysfunction Natural testosterone boosters also play a crucial role in regulating weight gain and supporting the production of steroid hormones, which are essential for muscle growth, energy, and sexual function. Many of these ingredients help modulate the activity of the adrenal glands—important organs that influence both cortisol and testosterone levels. In addition, a healthy intake of dietary fat is vital for optimal hormone synthesis, as extremely low fat diets can negatively impact testosterone and other steroid hormones. By promoting the body's natural ability to maintain healthy fat levels and supporting key processes related to sexual function, muscle repair, and hormonal balance, these supplements offer a comprehensive approach to men's health and performance. Final Thoughts: The Future of Natural Testosterone Therapy The landscape of men's health and muscle building is changing rapidly. In 2025, more men than ever are seeking safe, effective, and convenient testosterone therapy—without the needles, risks, or doctor's visits of traditional TRT. TestoPrime stands at the forefront of this movement, offering a powerful, natural testosterone treatment for men who want to maximize muscle mass, performance, and vitality. Its evidence-based formula, stellar safety profile, and growing community of success stories make it the leading choice for anyone ready to take their training and life to the next level. Ready to experience the benefits of natural testosterone boosters? Discover TestoPrime and join the new era of muscle building and men's health today. Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any supplement. Individual results may vary. Media Contact:Steve Niddich, Head of Product InnovationWolfson Brands UK12 Payne Street, Glasgow, G4 0LF, United Kingdomsupport@ TestoPrime CONTACT: Media Contact: Steve Niddich, Head of Product Innovation Wolfson Brands UK 12 Payne Street, Glasgow, G4 0LF, United Kingdom support@
