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Israel to launch world's first human spinal cord transplant using patient's own cells

Israel to launch world's first human spinal cord transplant using patient's own cells

Time of India7 hours ago
In a groundbreaking development in
regenerative medicine
,
Israeli scientists
are getting ready to perform the world's first
spinal cord transplant
using a patient's own cells. Announced on August 20, 2025, by
Tel Aviv University
, this pioneering procedure could redefine the treatment options for spinal cord injury diagnosis and give new hope for patients who have long faced restricted options.
A Revolutionary Surgical Approach
The surgery will involve transplanting a patient's own cells into the damaged areas of the spinal cord. The aim is to restore lost functions, allowing patients to regain mobility. Unlike traditional treatments that rely on donor tissues or artificial implants, this process leverages the patient's biological material, minimizing the risk of rejection and enhancing the chances of successful integration.
Experts regard that this approach represents a major leap forward in spinal cord therapy. By leveraging the patient's own cells, doctors focus to stimulate
neural regeneration
and repair, allowing individuals to walk again after severe injuries. If successful, the process could set a global precedent for how
spinal cord injuries
are diagnosed in the future.
Impact on Patients' Lives
Spinal cord injuries usually result in permanent loss of sensation and movement, then affecting quality of life. The innovative transplant will mitigate these effects by repairing neural pathways and initiating recovery. For patients and families who have faced the long-term issues of immobility, this breakthrough could bring renewed hope for rehabilitation and renewed independence.
Israel's Role in Medical Innovation
Israel has long been at the forefront of medical research, with advancements spanning oncology, cardiology, and neurology. The upcoming spinal cord transplant highlights the country's commitment to pioneering answers that push the boundaries of conventional medicine. Collaboration between Tel Aviv University and leading medical institutions demonstrates how academic research can be translated into clinical practice, benefiting patients worldwide.
Live Events
FAQs:
Q1. What is a spinal cord transplant?
A1. A spinal cord transplant is a medical process that focuses to repair damaged spinal tissue, restore lost neural functions, and potentially enable patients to regain mobility.
Q2. How does regenerative medicine work?
A2. Regenerative medicine uses the body's own cells or biological materials to repair, replace, or regenerate damaged tissues and organs, initiating natural healing and recovery.
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Israel to launch world's first human spinal cord transplant using patient's own cells
Israel to launch world's first human spinal cord transplant using patient's own cells

Economic Times

time6 hours ago

  • Economic Times

Israel to launch world's first human spinal cord transplant using patient's own cells

Israel is set to perform the world's first spinal cord transplant using a patient's own cells, marking a historic milestone in regenerative medicine. The process focuses on repairing damaged neural pathways, restoring mobility, and improving quality of life for patients with spinal injuries, setting a new global standard for innovative medical diagnosis. Tired of too many ads? Remove Ads A Revolutionary Surgical Approach Impact on Patients' Lives Israel's Role in Medical Innovation Tired of too many ads? Remove Ads FAQs: In a groundbreaking development in regenerative medicine Israeli scientists are getting ready to perform the world's first spinal cord transplant using a patient's own cells. Announced on August 20, 2025, by Tel Aviv University , this pioneering procedure could redefine the treatment options for spinal cord injury diagnosis and give new hope for patients who have long faced restricted surgery will involve transplanting a patient's own cells into the damaged areas of the spinal cord. The aim is to restore lost functions, allowing patients to regain mobility. Unlike traditional treatments that rely on donor tissues or artificial implants, this process leverages the patient's biological material, minimizing the risk of rejection and enhancing the chances of successful regard that this approach represents a major leap forward in spinal cord therapy. By leveraging the patient's own cells, doctors focus to stimulate neural regeneration and repair, allowing individuals to walk again after severe injuries. If successful, the process could set a global precedent for how spinal cord injuries are diagnosed in the cord injuries usually result in permanent loss of sensation and movement, then affecting quality of life. The innovative transplant will mitigate these effects by repairing neural pathways and initiating recovery. For patients and families who have faced the long-term issues of immobility, this breakthrough could bring renewed hope for rehabilitation and renewed has long been at the forefront of medical research, with advancements spanning oncology, cardiology, and neurology. The upcoming spinal cord transplant highlights the country's commitment to pioneering answers that push the boundaries of conventional medicine. Collaboration between Tel Aviv University and leading medical institutions demonstrates how academic research can be translated into clinical practice, benefiting patients worldwide.A1. A spinal cord transplant is a medical process that focuses to repair damaged spinal tissue, restore lost neural functions, and potentially enable patients to regain mobility.A2. Regenerative medicine uses the body's own cells or biological materials to repair, replace, or regenerate damaged tissues and organs, initiating natural healing and recovery.

Israel to launch world's first human spinal cord transplant using patient's own cells
Israel to launch world's first human spinal cord transplant using patient's own cells

Time of India

time7 hours ago

  • Time of India

Israel to launch world's first human spinal cord transplant using patient's own cells

In a groundbreaking development in regenerative medicine , Israeli scientists are getting ready to perform the world's first spinal cord transplant using a patient's own cells. Announced on August 20, 2025, by Tel Aviv University , this pioneering procedure could redefine the treatment options for spinal cord injury diagnosis and give new hope for patients who have long faced restricted options. A Revolutionary Surgical Approach The surgery will involve transplanting a patient's own cells into the damaged areas of the spinal cord. The aim is to restore lost functions, allowing patients to regain mobility. Unlike traditional treatments that rely on donor tissues or artificial implants, this process leverages the patient's biological material, minimizing the risk of rejection and enhancing the chances of successful integration. Experts regard that this approach represents a major leap forward in spinal cord therapy. By leveraging the patient's own cells, doctors focus to stimulate neural regeneration and repair, allowing individuals to walk again after severe injuries. If successful, the process could set a global precedent for how spinal cord injuries are diagnosed in the future. Impact on Patients' Lives Spinal cord injuries usually result in permanent loss of sensation and movement, then affecting quality of life. The innovative transplant will mitigate these effects by repairing neural pathways and initiating recovery. For patients and families who have faced the long-term issues of immobility, this breakthrough could bring renewed hope for rehabilitation and renewed independence. Israel's Role in Medical Innovation Israel has long been at the forefront of medical research, with advancements spanning oncology, cardiology, and neurology. The upcoming spinal cord transplant highlights the country's commitment to pioneering answers that push the boundaries of conventional medicine. Collaboration between Tel Aviv University and leading medical institutions demonstrates how academic research can be translated into clinical practice, benefiting patients worldwide. Live Events FAQs: Q1. What is a spinal cord transplant? A1. A spinal cord transplant is a medical process that focuses to repair damaged spinal tissue, restore lost neural functions, and potentially enable patients to regain mobility. Q2. How does regenerative medicine work? A2. Regenerative medicine uses the body's own cells or biological materials to repair, replace, or regenerate damaged tissues and organs, initiating natural healing and recovery.

Worlds first human spinal cord implant to take place in Israel
Worlds first human spinal cord implant to take place in Israel

News18

time7 hours ago

  • News18

Worlds first human spinal cord implant to take place in Israel

Tel Aviv [Israel], August 20 (ANI/TPS): Israel is preparing to perform the world's first-ever human spinal cord implant using a patient's own cells, a medical breakthrough that could allow paralysed patients to stand and walk again, Tel Aviv University announced on surgery, expected in the coming months, will take place in Israel and marks a historic milestone in regenerative to the World Health Organisation, over 15 million people worldwide are living with spinal cord injuries, with the majority resulting from traumatic causes such as falls, road traffic accidents, and spinal cord injuries cannot be fully cured, so treatment focuses on stabilising the patient, preventing further damage, and maximising function. Emergency care often involves immobilising the spine, reducing inflammation, and sometimes performing surgery to repair fractures or relieve pressure. Rehabilitation includes physical and occupational therapy, as well as assistive devices like wheelchairs and braces. While experimental therapies–including stem cells and robotic devices–are being explored, no treatment yet reliably restores full spinal cord cord injuries are one of the few human injuries where the body cannot naturally heal itself, and the tissue is both structurally complex and extremely sensitive.'The spinal cord transmits electrical signals from the brain to all parts of the body. When it is severed by trauma such as a car accident, a fall, or a combat injury, the chain is broken. Think of an electrical cable that has been cut: when the two ends no longer touch, the signal cannot pass, and the patient remains paralysed below the injury," explained Professor Tal Dvir, head of the Sagol Centre for Regenerative Biotechnology and the Nanotechnology Centre at Tel Aviv University, who is leading the effort. Dvir is also the chief scientist at Matricelf, the Israeli biotech company commercialising the other tissues, spinal cord neurons cannot naturally regenerate, and over time, scar tissue blocks remaining signals. The new procedure aims to replace the damaged section with a lab-grown spinal cord that fuses with healthy tissue above and below the injury. Animal studies in rats have shown remarkable results, with the animals regaining the ability to walk innovation began about three years ago, when Dvir's lab engineered a personalised three-dimensional human spinal cord in the laboratory. The findings, published in the peer-reviewed journal Advanced Science, showed that mice with chronic paralysis regained mobility after receiving the engineered procedure begins with blood cells from the patient, which are reprogrammed into stem-cell-like cells capable of becoming any cell type. Fat tissue is also collected to create a custom hydrogel scaffold, into which the stem-like cells develop into a spinal cord structure. This engineered tissue is then implanted, replacing scarred areas and reconnecting the nervous system.A few months ago, Prof. Dvir and his team received preliminary approval from Israel's Ministry of Health for 'compassionate use" trials in eight patients, making Israel the first country to attempt this procedure. 'This is undoubtedly a matter of national pride. The technology was developed here in Israel, at Tel Aviv University and at Matricelf, and from the very beginning it was clear to us that the first-ever surgery would be performed in Israel, with an Israeli patient," Dvir technology was then commercialised through Matricelf, which was founded in 2019 under a licensing agreement with Tel Aviv University's technology transfer company, Ramot.'This milestone marks the shift from pioneering research to patient treatment. Using each patient's own cells eliminates key safety risks and positions Matricelf at the forefront of regenerative medicine. This first procedure is more than a scientific breakthrough; it is a step toward transforming an area of medicine long considered untreatable," said Matricelf CEO Gil added, 'If successful, this therapy could define a new standard of care in spinal cord repair, addressing a multi-billion-dollar market with no effective solutions today. We are proud that Israel is leading this global effort and are fully committed to bringing this innovation to patients worldwide."'Our goal is to help paralysed patients rise from their wheelchairs. The animal model trials showed extraordinary success, and we are hopeful that the results in humans will be just as promising," Dvir said. (ANI/TPS)

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