Osteoarchaeologist Uncovers Shocking Link Between Brain Condition and Neanderthals
A new study suggests that Chiari malformation type I, a brain abnormality that affects up to 1 in 100 people, may be tied to DNA inherited from Neanderthals. The condition happens when the lower part of the brain extends into the spinal canal, often causing severe headaches, neck pain, and other complications.
Researchers had long suspected that interbreeding between Homo sapiens and ancient hominin species could play a role in the shape mismatch between the brain and skull that leads to this defect. But this new research points a finger squarely at Neanderthals, not other early human relatives like Homo erectus or Homo heidelbergensis.
Led by osteoarchaeologist Kimberly Plomp at the University of the Philippines, Science Alert reports the team used 3D modeling and skull shape analysis on more than 100 modern human skulls, comparing those with Chiari malformation to those without. They also examined eight fossil skulls from ancient species, including Neanderthals.
Their finding? Only the skulls of Neanderthals showed a similarity to the bone structure of modern people with Chiari malformations, especially in the area where the brain meets the spine.
This challenges an earlier theory from 2013 that broadly connected the defect to multiple ancient human species.
Instead, researchers now propose what they're calling the Neanderthal Introgression Hypothesis, suggesting the condition may trace specifically back to Neanderthal ancestry.
The next step is expanding the study to include more skull samples and testing across different populations. Since African groups have far less Neanderthal DNA than European or Asian groups, future research could reveal patterns in how widespread the condition is based on genetic inheritance.
Ultimately, understanding this ancient connection could offer new insight into diagnosing and possibly preventing Chiari malformations. The researchers believe their methods could help unravel the causes of the condition and lead to better treatment options.Osteoarchaeologist Uncovers Shocking Link Between Brain Condition and Neanderthals first appeared on Men's Journal on Jul 16, 2025
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