What you need to know about weight loss jabs as price of Mounjaro jumps 170%
People in the UK paying privately for the weight-loss jab Mounjaro are set to face higher costs, after its manufacturer Eli Lilly has said it will raise the drug's list price by up to 170%.
The company says the increase will bring UK prices closer to those in other European countries, where the weekly injection is already sold for significantly more, according to the BBC.
The change reportedly won't affect the NHS, which pays a lower negotiated price, but most UK users buy it privately – often from pharmacies or online – so many could soon face higher costs.
Mounjaro works by helping people feel fuller for longer, so they eat less. It's been shown to help some users lose as much as 20% of their body weight.
Here's what you need to know.
Which is considered the 'best' weight loss jab?
Previous findings in The New England Journal of Medicine showed Mounjaro led to bigger drops in waist size, blood pressure and cholesterol than other weight loss jabs.
In a study of 750 adults with obesity, those on Mounjaro lost around 20% of their body weight over 72 weeks, compared to 14% of those taking Wegovy. The research was funded by the Mounjaro's manufacturer Eli Lilly,
Both medications suppress appetite by flipping an 'appetite switch' in the brain, making the patient feel fuller for longer.
However, Mounjaro targets two hunger-regulating hormones over Wegovy's one, which may explain its stronger effect.
Who is eligible for weight loss jabs on the NHS?
The two most popular weight-loss jabs are Mounjaro and Wegovy, and eligibility differs slightly for each:
Mounjaro (tirzepatide)
Mounjaro is approved for weight loss and weight management in adults aged 18 and over who meet the eligibility criteria. It works by regulating a person's appetite so they feel full, making them feel less hungry and experience fewer food cravings.
It is recommended that Mounjaro be used together with a reduced-calorie diet and increased physical activity.
You are eligible for Mounjaro if you meet the following criteria:
Have a BMI of at least 30
Have a BMI between 27 to 30, and weight-related problems such as prediabetes, high blood pressure, high cholesterol, or heart problems
Mounjaro is available as a pre-filled injection pen that is to be injected under the skin of your stomach area, thigh or upper arm. The starting dose is 2.5mg once a week for four weeks, increasing to 5mg once a week.
According to the Medicines and Healthcare products Regulatory Agency (MHRA), the dose may then be increased in at least four-week intervals up to the maximum dose of 15mg per week.
Women using oral contraceptives may be advised to consider using a barrier method of contraception, such as a condom or switching to a non-oral contraceptive method for four weeks after starting Mounjaro. This is because Mounjaro may affect the efficacy of the contraceptive pill.
Wegovy (semaglutide)
Wegovy is the brand name for semaglutide which is licensed and approved for managing obesity. It differs from Ozempic, which is another brand name for semaglutide and is used for treating obesity as well as type 2 diabetes. Ozempic should not be prescribed solely for weight loss.
The NHS began offering Wegovy in September 2023 as an option for weight management in line with guidance from the National Institute for Health and Care Excellence (NICE).
It is recommended that the medication be used in tandem with a reduced-calorie diet and increased physical activity.
You are eligible for Wegovy if you meet the following criteria:
Have a Body Mass Index (BMI) of at least 35
One weight-related comorbidity (such as hypertension or cardiovascular disease)
Have a BMI of 30 to 34.9, provided you meet the criteria for referral to specialist weight management services
The Department for Health and Social Care adds: "Wegovy is for those dealing with obesity and weight-related problems, not for people who just want to lose some weight."
Wegovy is taken via an injection once a week. Should you meet the eligibility criteria and are prescribed Wegovy, your healthcare team will give you more information about how to take it and how to inject it.
How much do weight loss jabs cost?
At present, the drugs can be bought privately from high street chemists and online pharmacies after an in-person or video consultation with a specialist.
A private prescription can currently cost upwards of £122-£150 a month, but from September, will increase to £330 a month, though the price hike for smaller doses could be less.
It's estimated more than half a million people are getting injections this way because of the long wait time for specialist NHS clinics.
The move comes as US president Donald Trump ramps up pressure on drugmakers to increase their prices for Europeans so Americans can more easily afford them, reports The Guardian.
Will a weight loss pill be cheaper?
A weight-loss pill is also in the works. A daily tablet called orforglipron, made by the same company as Mounjaro, has shown promising early trial results, helping people lose an average of 12.4% of their body weight over 72 weeks.
Eli Lilly plans to seek approval by the end of the year, and while the pill would likely be cheaper to produce than weekly jabs (it doesn't have a price point yet), the news of the Mounjaro price hike may raise questions about how affordable it will be if sold privately.
Do patients get a say in which weight-loss medication they're prescribed?
While patients can discuss options with their healthcare provider, the choice of drug such as Mounjaro or Wegovy and whether it's in pill or jab form, will typically be guided by clinical need, NICE guidelines, and NHS availability.
Eligibility is based on the factors above, such as BMI and weight-related health conditions. So even if pharmacy prescribing is rolled out more widely, treatment decisions will likely still be based on medical assessment rather than patient request, at least for now.
Earlier this year, online pharmacies were told they must conduct a proper two-way consultation with patients before prescribing weight loss jabs
The General Pharmaceutical Council (GPhC), which regulates pharmacies, said it was responding to concerns relating to the unsafe prescribing and supply of medicines like weight loss jabs online.
Read more about weight loss:
Who can get new weight-loss jab Mounjaro on the NHS? (Yahoo Life UK, 4-min read)
What to know about game-changing new weight-loss pill that could be prescribed on the NHS (Yahoo Life UK, 4-min read)
Obesity rates may start falling this year due to weight loss jabs, seller says (Sky News, 4-min read)

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