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What's your ‘biological age'? And here's how to lower it…

What's your ‘biological age'? And here's how to lower it…

BreakingNews.ie22-06-2025
It's no secret that wellness fads come as quickly as they go. From the low-fat diets of the Noughties to the UPF-free food of today – society loves indulging in the newest health hack.
The newest wellness trend to step onto the scene is 'biohacking'. You may have heard of it via Bryan Johnson's infamous anti-ageing quest, or simply by the numerous podcasts that now discuss cell health and biological age.
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But what really is biohacking? How do you find out your biological age? And does it really determine how long you'll live for?
Doctors specialising in stem cell and longevity research explain what biological age
really
means, how to lower it and why it's fast becoming the ultimate wellness metric in modern medicine.
What is biological age?
Biological age – a measurement of how well your body is functioning based on factors like lifestyle, stress and cellular health – is different to chronological age, as it isn't fixed, and (perhaps thankfully) you can reverse it.
According to longevity experts, biological age provides a more accurate picture of health span than the candles on our birthday cake. And increasingly, it's being treated as something we can influence.
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Chief executive of Cellcolabs, Dr Mattias Bernow, who provided the stem cells for biohacker Bryan Johnson, explains that this measurement is, 'a marker of how old your body seems based on your health, lifestyle and cellular function.' In other words, you might be 50 on paper, but living like someone 35 – or 65.
'Two people who are both 40 years old chronologically might have very different biological ages depending on how they live, their stress levels, their metabolic health and more,' says GP and founder of London's longevity clinic, HUM2N, Dr Mohammed Enayat.
What accelerates biological ageing?
The good news is that many of the biggest culprits behind accelerated ageing are changeable. Both Enayat and Bernow point to chronic stress, poor sleep, lack of exercise, ultra-processed foods and environmental toxins as major accelerants.
Parenting itself doesn't inherently age the body, but, as Enayat points out, the chronic sleep deprivation and stress associated with caregiving certainly can.
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Lack of sleep caused by parenting can increase your biological age
Inflammation is another central player. 'These factors contribute to increasing low-grade inflammation,' Bernow explains, 'which plays a key role in age-related decline and the development of chronic disease.'
But this process, he says, is not set in stone. 'While we can't control everything, small, consistent changes to reduce these stressors can make a meaningful difference in how we age.'
Which lifestyle changes have the biggest scientific backing when it comes to reversing it?
When it comes to slowing the clock, it turns out the best advice isn't ground-breaking – it's just often overlooked.
Quality sleep, regular movement, a balanced whole-food diet, meaningful relationships and avoiding harmful substances all rank highly on the evidence-based list.
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Enayat also points to practices like caloric moderation, intermittent fasting and resistance training for their 'strong results in slowing biological ageing at a cellular level.'
However, these diets impact each sex differently, with intermittent fasting in particular causing more stress on women's bodies while being effective for men, meaning they will affect biological age differently.
How big a part do genetics play?
Though it's tempting to think of ageing as a genetic lottery, our DNA doesn't write the full script. 'Genes load the gun, but lifestyle pulls the trigger,' Enayat says, noting that genetics may only account for 20 to 30 per cent of ageing outcomes.
Bernow says that emerging research suggests as much as 80 per cent of ageing is governed by one's environment and behaviour.
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Do supplements
actually
make a difference?
Supplements claim everything from healthier skin to better energy to thicker hair – but it's fair to be sceptical of whether they really make a difference, or if it's all marketing.
However, there are some supplements that have been proven to be helpful if taken correctly and absorbed properly. 'Protein is essential for preserving muscle mass,' says Enayat, while collagen 'may help with skin and joint health,' though its systemic anti-ageing benefits are modest.
Some supplements can make a difference if taken and absorbed correctly
Fish oil, magnesium, creatine and polyphenols all show promise too, but Enayat is keen to emphasise that supplement should support – not replace – healthy habits.
Bernow cautions that while some supplements, like vitamin D, are well-supported (especially in sun-deprived regions), many products on the market are poorly regulated. 'Supplements are not a substitute for healthy habits,' he says, 'but in some cases, they can play a supportive role if used thoughtfully.'
How to find out your biological age and what healthy habits the experts incorporate
If this has sparked a curiosity to find out your own biological age, figuring it out requires a blood test.
'The most validated tests look at DNA methylation patterns,' says Enayat, and suggests well-known tests like the Horvath Clock, GlycanAge and TruAge.
Bernow says that Bryan Johnson uses the DunedinPACE test, which claims to show he's ageing at just 0.66 years per year (66% of his chronological age).
As for how these experts practise what they preach – they say it's all about balance and consistency.
Moderate, low impact exercise can actually lower biological age
Enayat's daily habits include either walking, strength training or stretching, prioritising plants and healthy fats, regular fasting, cold exposure and supplementing with omega-3, vitamin D, magnesium and creatine. 'The goal is consistency, not perfection,' he says.
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Bernow takes a similar approach, but with less exercise and more socialising, explaining he takes a short morning workout, has plenty of family time, eats balanced meals and drinks minimal alcohol.
'More than anything, I believe in consistency,' he says. 'Longevity isn't about extremes but about the things you do every day, for years.'
So, while biohacking might conjure visions of futuristic and expensive tech, the real secret to ageing well is actually much simpler – by prioritising balance and relaxation – not difficult at all in today's world!
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Should you go to bed at 8.30pm? Here's what the experts say
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Should you go to bed at 8.30pm? Here's what the experts say

It's 9pm and Bryan Johnson is up past his usual bedtime of 8.30pm. Here, in the penthouse apartment of Michael Acton Smith, founder of the Calm app, Johnson — the tech entrepreneur who spends $2 million a year trying to reverse ageing — is telling a hand-picked audience of longevity nerds about his famously restrictive 'Don't Die' regime, which he aims to turn into 'a religion'. For Johnson, sleep trumps the hundreds of supplements, experimental medications and therapies he takes. In pursuit of being a 'sleep professional', as he calls it, he never drinks caffeine or alcohol, or has food after midday, so that 'Sleepy Bryan' can get world-class shut-eye. Thanks to his Whoop fitness tracker, this sleep pro can get feedback on his performance from the boss — his body. But, at 47, Johnson is not the only adult to go to bed at the same time as the average ten-year-old. And he's not alone in his belief that sleep is a sacrament. 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And ignore the rich and famous cult leaders, or we risk making sleep another dispiriting wellness goal to fail at.'

Vinay Prasad returns to FDA days after leaving under pressure from Laura Loomer
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time3 hours ago

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