
Week-long GAIN course on models, algorithms for omics data analysis at BHU
Varanasi: A week-long GIAN course on Models and Algorithms For Omics Data Analysis was organised by the School of Biotechnology, Institute of Science, BHU from June 2 to 6 under the Ministry of Education's initiative of Global Initiative of Academic Networks (GIAN).
The initiative aims to enhance the country's existing academic resources, accelerate the pace of quality improvement, and elevate India's scientific and technological capability to global excellence. Prof Rajeev Kumar Azad from the Department of Biological Sciences at the University of North Texas, USA, shared his expert inputs during the course. tnn
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Time of India
2 days ago
- Time of India
Week-long GAIN course on models, algorithms for omics data analysis at BHU
Varanasi: A week-long GIAN course on Models and Algorithms For Omics Data Analysis was organised by the School of Biotechnology, Institute of Science, BHU from June 2 to 6 under the Ministry of Education's initiative of Global Initiative of Academic Networks (GIAN). The initiative aims to enhance the country's existing academic resources, accelerate the pace of quality improvement, and elevate India's scientific and technological capability to global excellence. Prof Rajeev Kumar Azad from the Department of Biological Sciences at the University of North Texas, USA, shared his expert inputs during the course. tnn


Time of India
3 days ago
- Time of India
New genetic markers offer hope for early detection of gallbladder cancer
Varanasi: Research scholars from Banaras Hindu University, Dr Ruhi Dixit, Dr Manoj Pandey and Dr Vijay Kumar Shukla, achieved breakthrough in gallbladder cancer research by identifying novel genetic biomarkers that could transform early detection and targeted treatment of this deadly disease. Using advanced Clariom D Microarray technology , the team analysed gene expression profiles from gallbladder cancer, cholelithiasis (gallstones) and healthy tissues. Dr Dixit said it was first time in India, a three-way comparative transcriptomic analysis revealed 10 key genes potential drivers of cancer growth. Most of these genes are involved in DNA repair so their dysfunction promotes growth of cancer. The study suggests that, regardless of carcinogenic trigger, genetic pathways primarily involve DNA repair mechanisms , making treatment challenging. Building on the team's prior transcriptomic study, these findings clarify pathways in carcinogenesis and differential gene expression. Additionally, five genes were common across all three groups, indicating their potential as markers of early transformation before cancer is full-fledged. The study identified 3,898 genes, of which 2,575 were upregulated and 1,323 were downregulated. Mismatch repair pathway, nucleotide excision repair, and homologous recombination were the main pathways were found to be involved in carcinogenesis. He said gallbladder cancer was among most common cancers in Gangetic belt, often diagnosed late with poor prognosis and a 5-year survival rate of 10-20 per cent. Despite 25 years research at BHU to identify its elusive causes, the study marks a significant advance. It is the first in India to compare genetic changes across cancer, gallstone and healthy tissues simultaneously. The newly identified genes could serve as biomarkers for early detection and personalised treatment, paving way for improved diagnosis, prognosis and therapy for gallbladder cancer.


Time of India
4 days ago
- Time of India
IIT-BHU increases 111 seats in popular depts for JEE qualified students
Varanasi: The Indian Institute of Technology-Banaras Hindu University, Varanasi, has increased 111 seats in its most popular departments for students qualifying through the Joint Entrance Examination (JEE). For the 2025-26 academic year, the institute will offer a total of 1,589 seats for the first-year students, the same as last year. However, seats were moved around to better meet the demand. Specifically, 111 seats were reduced in four departments—ceramic engineering, metallurgical engineering, mining engineering, and pharmaceutical engineering & technology—and given to nine high-demand departments like computer science and engineering, electronics engineering, mathematics and computing. Four departments remained unaffected. IIT-BHU director prof Amit Patra said, "We are constantly working to ensure that our academic offerings match the aspirations of our students and the needs of the industry. This reallocation of seats in high-demand departments will provide more opportunities for talented students to pursue their chosen fields and contribute meaningfully to technological advancement and nation-building." As per the count provided by the institute, as compared to the 2024-25 session, the number of seats in 2025-26 reduced from 14 to 41 in ceramic engineering, metallurgical, mining, and pharmaceutical engineering. The maximum reduction in the figure of seats—41—was in mining engineering. The seats increased from three to 22 in chemical engineering, civil, computer science, electrical, electronics, mechanical, architecture, biochemical, bioengineering, materials science and technology, mathematics and computing, engineering physics, and industrial chemistry. The number of total seats (1,589) is unchanged.