Gene Hackman's Wife Deteriorated Fast With Rare Hantavirus, Expert Says
Here is the deal ... Santa Fe authorities on Friday shared the shocking revelation that Betsy Arakawa likely died a week before Gene -- and it was the rare virus spread by rats and mice that killed her.
Dr. Jeffrey Klausner, an infectious disease expert and professor at the Keck School of Medicine of USC, tells TMZ ... Hantavirus impacts the body fast – and since symptoms present themselves as a chest cold -- and the virus is so rare -- it is often misdiagnosed.
Hantavirus spreads to humans from rat/mouse poop and urine, which usually is contracted when someone cleans the attic or basement ... and it kills one in three people, Dr. Klausner tells us.
Like any other severe virus, the percentage of survival is much greater if it's diagnosed immediately and the person is hospitalized ... with Klausner telling TMZ Hantavirus is akin to severe pneumonia.
As for her final days ... Betsy was likely having a harder and harder time breathing, until she finally lost consciousness in the bathroom and died.
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As we previously reported ... Authorities believe Gene -- who we now know had Alzheimer's -- died a week later of heart disease and complications caused by the disease.

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Newsweek
21 hours ago
- Newsweek
Woman in Psych Unit Diagnosed With Dementia at 56, It Was Menopause
Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. This time last year, Hayley, 57, was sectioned and admitted to a psychiatric unit. She was suffering from intense psychosis, paranoia and depression. Her behavior had changed so drastically that she no longer recognized her own family. Her speech was incoherent, her thoughts disordered and she was experiencing vivid hallucinations. Doctors told her family that it's likely to be frontotemporal dementia (FTD)—a rare and devastating neurological condition that typically affects people between 45 and 64. Unlike Alzheimer's, FTD often causes dramatic personality changes, emotional withdrawal and problems with speech, movement and decision-making. But the diagnosis was wrong. Hayley wasn't losing her mind to dementia. She was going through menopause. Screenshots from TikTok showing Jay's face over an image of his mom when she was sectioned. A more recent photo of Hayley. Screenshots from TikTok showing Jay's face over an image of his mom when she was sectioned. A more recent photo of Hayley. TikTok/@drlouisenewson Menopause is a natural stage in a woman's life when her periods stop, marking the end of fertility. But it can also be a time of extreme vulnerability. Hormonal changes can trigger or worsen mental health conditions, including serious ones like psychosis. In Hayley's case, the symptoms were so severe and sudden that even specialists believed she had a degenerative brain disease. Newsweek spoke with Hayley and her 25-year-old son, Jay, about the misdiagnosis that upended their lives. "We were all completely devastated," Jay said. "At the time, it was totally believable. Mom's ability to communicate was deteriorating, her psychosis meant she couldn't recognize us, and her hallucinations were getting worse. "Upon hearing the news of a potential dementia diagnosis, it felt like the final stage in a long-standing journey of suffering." Misdiagnosis and Hospitalization Jay was heartbroken by his mom's diagnosis, but then a family friend suggested it could have to do with her hormones. Desperate for answers, he began researching alternative explanations. That's when he discovered Dr. Louise Newson, a leading U.K. menopause specialist known for transforming how menopause is understood and treated. Dr. Louise Newson. Dr. Louise Newson. Provided by Dr. Newson Speaking with Newsweek, Newson explained how menopause symptoms—including memory loss, brain fog, poor concentration and low mood—can closely resemble the early signs of dementia. "This can lead to confusion or misdiagnosis, with women being told they have cognitive decline when in fact their symptoms are due to hormonal changes," she said. "It has been known for many decades that the hormones oestradiol, progesterone and testosterone all have important and beneficial effects on the function of the brain—improving the way the cells and nerves work as well as working as neurotransmitters. "These hormones reduce inflammation in the brain and also improve blood supply to the brain." Battle for Treatment In a detailed TikTok video shared to @drlouisenewson, Jay highlights how medics refused to believe Hayley's condition was linked to her hormones. "Jay struggled to convince the psychiatrists to prescribe body-identical hormones, and it wasn't until they discussed with Dr. Newson that they eventually agreed to prescribe them some months later," Hayley told Newsweek. From left: Jay, 25, mom Hayley, 57, and Dr. Louise Newson. From left: Jay, 25, mom Hayley, 57, and Dr. Louise Newson. The Dr Louise Newson Podcast She began taking HRT and testosterone in September 2024 and it took from four to eight weeks for depression and psychosis to subside. "I recall one day feeling like something had lifted, and then I spent moments in the subsequent weeks crying as I realized what had been happening. "Coming back into reality after years of suffering was extremely overwhelming and daunting at first. By the 12th week of HRT, I had returned to reality and was fortunate enough to spend Christmas with my son," she said. History of Mental Health Struggles After suffering with postpartum psychosis with all three of her children, Hayley has spent most of her adult life in and out of mental health units. In 2010, she was diagnosed with schizoaffective disorder—a mental health condition that is marked by a mix of schizophrenia symptoms such as hallucinations and delusions, and mood disorder symptoms. "From 48, my mental health and cognitive condition deteriorated significantly," she said, "and I was unable to recover, spending a lot of the time sectioned on psychiatric wards." Hormones and Mental Health Newson said: "Hormonal changes are a major factor in many women's mental health, particularly during the perimenopause and after childbirth, as well as women with premenstrual dysphoric disorder (PMDD), yet they're often overlooked in psychiatric care. "As a result of this inadequate education, women are frequently given antidepressants, antipsychotics and other unnecessary treatments without exploring whether hormonal changes might be part of the cause. Women need to have a more informed approach that considers both mental health and hormones together." Hayley became agoraphobic as her delusions made it hard to leave her home and she self-medicated with alcohol. Screenshots from TikTok showing Hayley and her son enjoying a Robbie Williams concert this summer. Screenshots from TikTok showing Hayley and her son enjoying a Robbie Williams concert this summer. TikTok/@drlouisenewson Life After Recovery "Since my recovery with HRT, I love having my grandchildren stay with me at the weekends and we have the loveliest of times," Hayley said. "I also spend time with my children enjoying concerts, meals out and doing the things we missed out on as they grew up. "I have a newfound lust for life and motivation which I haven't experienced in decades. Few things worry me and my confidence has generally returned. Despite having suffered for most of my adulthood and the elements of lasting damage, I feel so fortunate to be able to finally create many special memories in such a short space of time." Now Hayley is making up for lost time with her family, something her son admires greatly. "Never in a million years did I think we would have ever achieved what we have done in the past year," he said. "I feel a great sense of achievement and satisfaction that the hard work and perseverance in advocating for my mum and finding the answers has paid off more than we ever could have imagined."


Los Angeles Times
2 days ago
- Los Angeles Times
Mother and daughter, diagnosed with breast cancer five days apart, ring the bell at Hoag
Jeannette Reding was diagnosed with Stage 1 breast cancer on Valentine's Day earlier this year. Hoag Hospital gave the same news to her daughter, Kristina Walters, five days later. The mother and daughter have always been close. They live in the same neighborhood in Orange. Now, they're both breast cancer survivors, and this experience over the last few months may have brought them together that much more. 'It's almost like it's been easier for my dad [Tony] and my husband [Mike],' said Kristina Walters, 43. 'My dad is a big worrier, but it was almost more calm. It was kind of a blessing in disguise, which is weird. You're not alone. You do feel alone, but you're really not. 'It wasn't like, 'Oh my God, poor us.' It was more like, 'Thank God we have each other.' Kind of crazy.' Walters finished her cancer treatments a couple of weeks ago. On Thursday, the family gathered as her mother also rang the bell signifying the completion of cancer treatment at the Hoag Family Cancer Institute in Newport Beach. Reding, 66, called it 'surreal' that her daughter was also diagnosed with cancer. 'I couldn't believe it,' she said. 'Here I am, and I have cancer, and she's invading my moment.' Both mother and daughter have gone in for mammograms each year, and catching the cancer early helped their chances. Walters had her breast cancer just on her right side — ductal carcinoma — while Reding had both ductal and lobular carcinoma. Each went through radiation, though they avoided chemotherapy. Reding said her older sister, Pat, who is also a breast cancer survivor and had a mastectomy, didn't go in to get checked out until she found a lump. Pat gave advice to both mother and daughter — and their experience highlights why early detection is important. 'Don't wait, just do it,' Walters said of her mammogram advice to other women. 'It's not a big deal, just get it done. That one year of waiting could change a lot of things. The technology nowadays is pretty incredible.' Dr. Elizabeth Kraft, a breast and oncoplastic surgeon at Hoag who treated both mother and daughter, said this is the first time in her decade in the field that she's seen two generations have breast cancer concurrently. Both had small enough tumors that they were eligible for oncoplastic surgery, which not only removes the tumor but allows for better cosmetic results for the breast. Walters underwent her oncoplastic surgery two weeks before Reding underwent a double lumpectomy with breast reconstruction. Both were performed by Kraft with help from Hoag plastic surgeons Nirav Savalia and Raquel Minasian, respectively. Kraft said her mentor, Dr. Mel Silverstein, was an innovator in oncoplastic surgery in the 1990s. He was recruited to Hoag in 2008 and started training other surgeons in a fellowship that was developed between USC and Hoag that Kraft herself went through before the partnership ended. Oncoplastic surgery is only offered in a couple of locations throughout the country, Kraft said, and the people teaching it came from the Hoag fellowship. 'I describe it to a patient like if you have a pizza,' Kraft said. 'If the whole pizza has a disease, you can't do much with that to make it a circle. But if we only have one slice of pizza we have to take out, we can really put the pizza back together in a nice way so that you're still the same shape and size. 'They're able to wear swimsuits again. They're able to wear the same bras. That stuff makes a difference, every day getting dressed. It was really amazing that we could offer them this. It's another positive outcome from this.' It adds up to a newsworthy story, something Mike Walters would know well. He's the co-founder and former news director at TMZ. The Walters' children — Tyler is 14 and Ava is 12 — were also able to attend Thursday's cancer bell ringing. Kristina said she will make sure that Ava goes through the proper screenings as she gets older. Kristina was emotional even before her mother rang the bell. 'Finally, it's over for her,' she said. 'It was hard watching her, because she was a lot more sore, and the burns and everything were harder for her. I was more happy for her, that she's done. She's not a complainer, but she's been in a lot of pain.' Reding certainly seemed to have a good sense of humor after ringing the bell. She had an area that didn't heal as well, which required medicated gauze each night. She said the smell was tough to bear for her husband, Tony. 'I lost my sense of smell during COVID, so it didn't bother me,' Reding said.


Medscape
2 days ago
- Medscape
Long-Term Use of Metformin May Prevent AMD in Diabetes
SOURCE: The study was led by Alexander T. Hong of the Keck School of Medicine of the University of Southern California in Los Angeles. It was published online Aug. 11, 2025, in Ophthalmology Retina . LIMITATIONS: Due to its retrospective design, the study could not show if taking metformin was actually protecting against AMD. There may have been coding errors and missing information as electronic health records data were used. The cohort analysis only included patients with annual health encounters for 5 years prior to the second eye care visit, potentially excluding those who changed institutions or had gaps in care. DISCLOSURES: The study was partly supported by grants from the National Eye Institute, Research to Prevent Blindness, Inc, and All May See Foundation, Inc. One author disclosed receiving consulting fees and having personal financial interests with certain organizations unrelated to this study. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. Lead image: The National Institute of Health