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Woman Tried To Get Pregnant For 4 Years, Turns Out She Is Allergic To Semen

Woman Tried To Get Pregnant For 4 Years, Turns Out She Is Allergic To Semen

News1825-07-2025
Last Updated:
After unprotected sex, the woman had sneezing, burning eyes and genital discomfort. Tests revealed SPH, a rare allergy where her body treated sperm proteins as harmful
In a rare and startling medical case, a 29-year-old woman from Lithuania was found to be allergic to her husband's semen, an unusual condition that explained her four-year struggle with infertility. Despite multiple natural attempts and two failed IVF procedures, conception remained out of reach.
Doctors were initially baffled, but detailed medical examinations finally revealed the hidden cause, shedding light on one of the rarest barriers to pregnancy.
The woman already suffered from asthma and allergies to dust, cat fur, and mould. Medical experts suspected her allergic nature might be causing her fertility issues. Blood tests showed she had elevated levels of eosinophils, white blood cells that help fight allergies.
Further skin tests revealed allergies to mites, pollen grains, insects, and dogs. Crucially, her body exhibited high sensitivity to the Can f 5 protein, found in dog dander and urine, and linked to human semen allergies.
Following unprotected sex, the woman experienced symptoms such as blocked nose, sneezing, burning eyes, and genital discomfort. Tests confirmed that she had Seminal Plasma Hypersensitivity (SPH), a rare allergy where a woman's body perceives sperm proteins as harmful and attacks them. SPH triggers severe reactions similar to those caused by peanuts or animal dander.
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First Published:
July 25, 2025, 18:46 IST
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