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A Southern Hemisphere First – New Cutting-Edge Radiotherapy now available at Icon Cancer Centre

A Southern Hemisphere First – New Cutting-Edge Radiotherapy now available at Icon Cancer Centre

Yahoo27-02-2025
PERTH, Australia, February 27, 2025--(BUSINESS WIRE)--Cancer patients being treated at Icon Group's Icon Cancer Centre Midland are now benefitting from the latest state-of-the-art radiation treatment planning and delivery technology with the introduction of Varian's RapidArc Dynamic solution.
Headquartered in Brisbane, Australia, Icon Group is a leading integrated cancer care provider with a growing global reach across Australia, New Zealand, Asia, and the United Kingdom. The decision to embrace RapidArc Dynamic was driven by strong early results showing faster treatment planning, reduced radiation exposure to healthy organs, and potential to set new standards in patient-centred care.
Icon is the first in the Southern Hemisphere and only the third worldwide to clinically treat with RapidArc Dynamic, marking a major step forward in radiation therapy, particularly for patients with breast and prostate cancer.
The introduction of RapidArc Dynamic technology at Icon has yielded significant data-driven improvements in treatment planning and execution including:
Treatment Planning Efficiency: With the use of advanced deterministic algorithms that automate key planning processes, RapidArc Dynamic has achieved up to an 80% reduction in treatment planning time for breast radiotherapy. This innovation enables clinicians to streamline treatment design, further reducing the number of arcs required from up to five down to a single arc per plan.
Reduced Radiation to Organs at Risk (OAR): Reduced radiation exposure to critical organs. For example, the mean dose to the heart has dropped by an average of 22%, lowering the risk of side effects and improving patients' quality of life.
Physician Confidence in Treatment Plans: In a recent blinded physician review, RapidArc Dynamic-based plans were selected as optimal in 100% of cases, demonstrating broad clinical confidence in the technology's ability to enhance plan quality and potentially yield better patient outcomes.
Prof. John Boyages AM, Icon Radiation Oncologist involved in RapidArc Dynamic's early plan quality evaluations, highlighted the clinical impact of this technology.
"I'm really excited about this technology. We already have some of the best treatment plans I've seen in my 40-year career at Icon, and this has just taken it to another level. I'm blown away by the ability to curve radiation around healthy organs and reduce doses to tissues like the heart to very safe levels whilst giving the right doses to the cancer areas," said Prof. Boyages.
The deployment of RapidArc Dynamic is anticipated to guide future dosimetry recommendations, especially for complex breast and nodal studies. The technology's potential for automated planning and initial success with other disease sites signal a shift toward establishing RapidArc Dynamic as a new standard of care in radiotherapy.
Icon Group CEO, Mark Middleton OAM says this highlights an ongoing commitment to reducing the global cancer burden.
"We're extremely proud of our long-term global partnership with Varian which has enabled us to be early adopters of new techniques and technologies," said Mark.
"RapidArc Dynamic adds to our suite of advanced radiotherapy treatments and techniques across our global network and is another example of our commitment to bringing world-class treatments to more communities across the world."
Icon is part of Varian's RapidArc Dynamic Consortium helping support ongoing data collection and clinical assessment, ensuring that patient outcomes continue to drive innovations in cancer treatment. Based on clinical data Icon has plans to introduce RapidArc Dynamic to more locations.
About Icon Group
Icon Group is a leading integrated provider of cancer care provider with a growing global reach in across Australia, New Zealand, ASEAN, Mainland China and the United Kingdom.
Icon is built on a strong but simple mission - to deliver the best care possible to as many people as possible, as close to home as possible. The group brings together all aspects of quality cancer care including medical oncology, haematology, radiation oncology, research, theranostics, pharmacy and compounding to deliver a truly integrated, end-to-end seamless service for cancer patients. With more than 3500 team members, a network of more than 350 doctors, over 50 cancer centres, six compounding facilities and operational support of 70 plus pharmacies, Icon is delivering world-leading care and helping address the global cancer burden.
For more information visit http://www.icongroup.global and follow Icon Group on LinkedIn at https://www.linkedin.com/company/icon-group
About Varian
At Varian, a Siemens Healthineers company, we envision a world without fear of cancer. For more than 75 years, Varian has developed, built, and delivered innovative technologies and solutions that help care providers around the globe treat millions of patients each year. Today, as a Siemens Healthineers company, we support every step of the cancer care journey – from screening to survivorship. From advanced imaging and radiation therapy to comprehensive software and services, to interventional radiology, we are harnessing the power of our perspective while also pursuing clinical research to create a more efficient, and more personalized care pathway. Because, for cancer patients everywhere, their fight is our fight. For more information, visit http://www.varian.com.
About Professor John Boyages AM
John is an internationally recognized radiation oncologist and breast cancer specialist with over 40 years of experience in diagnosing and treating breast cancer and trained at Sydney University's Westmead Hospital and at Harvard University in Boston. Throughout his career, Professor Boyages has pioneered innovative approaches in breast cancer detection and treatment, including establishing the Westmead Breast Cancer Institute and BreastScreen NSW Sydney West and the ALERT lymphoedema program at Macquarie University. He has published over 200 research papers and authored the "Taking Control" providing valuable resources for patients (bcpublish.com). Based at Icon Cancer Centre, Wahroonga (Sydney Adventist Hospital), John chairs, Icon's national breast interest group which is a forum for case discussion, peer-review and development of high-quality standards for breast radiation across Australia. He also Chairs Icon's planned Accelerated Partial breast Irradiation (APBI) study. John is available for interviews.
For more information on the RapidArc Dynamic solution and Icon's commitment to elevating standards in radiotherapy, please contact:
Varian: Tom.Harding@Varian.com Icon Group: media@icon.team
Disclaimer: RapidArc Dynamic is not available for sale in all countries and there is no guarantee of commercialization or feature availability.
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View source version on businesswire.com: https://www.businesswire.com/news/home/20250227005483/en/
Contacts
Tom Hardingtom.harding@varian.com +65 81381272
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Pulse Biosciences Reports Business Updates and Second Quarter 2025 Financial Results

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FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE™, AI-Guided Point of Care Ultrasound for the Management of Chronic Liver Diseases
FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE™, AI-Guided Point of Care Ultrasound for the Management of Chronic Liver Diseases

Business Wire

time2 hours ago

  • Business Wire

FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE™, AI-Guided Point of Care Ultrasound for the Management of Chronic Liver Diseases

VANCOUVER, British Columbia--(BUSINESS WIRE)--Sonic Incytes Medical Corp, proudly announces that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for Velacur ONE™, its point-of-care ultrasound elastography device. Building on the success of its original model, Velacur™, Velacur ONE™ introduces an enhanced interface and features for improved portability and user experience. These improvements enable broader scalability to support Sonic Incytes' accelerated US and global expansion strategy. Velacur ONE™ measures attenuation, VDFF (Velacur Determined-Fat Fraction), and liver stiffness using 3D S-WAVE and aids in the management of chronic liver disease including MASH and MASLD. The launch of Velacur ONE™ marks a pivotal milestone for Sonic Incytes as we accelerate our US and global commercial expansion strategy. Share Velacur ONE™ arrives at a critical time for improved non-invasive testing, following the recent FDA clearance of Rezdiffra—the first therapeutic for Metabolic dysfunction–associated steatohepatitis (MASH), a progressive and often underdiagnosed liver disease. In the U.S. alone, an estimated 100 million adults have Metabolic dysfunction–associated Steatotic Liver Disease (MASLD)1, with 15–20 million of those affected by MASH2. Yet, 90% of MASH cases remain undiagnosed3. If left untreated, worsening MASH increases morbidity and may progress to severe complications, including cirrhosis, liver failure, liver cancer, and liver transplant4,5. MASH remains challenging to diagnose effectively due to the limitations of existing non-invasive methods, especially those available at the point-of-care. With the first therapeutic now available and more in the pipeline, clinicians need improved non-invasive tests to diagnose and monitor MASH at point-of-care6. 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Velacur ONE™ combines this technology with a refined user interface, including B-mode imaging—enabling 3–4x higher reimbursement than non-imaging elastography—and an AI-based organ overlay feature to aid in liver localization, making it the only point-of-care device that estimates both liver stiffness and attenuation that correlates to MRI-PDFF10. 'The launch of Velacur ONE™ marks a pivotal milestone for Sonic Incytes as we accelerate our US and global commercial expansion strategy,' said Barry Allen, CEO of Sonic Incytes. 'This next-generation device enhances clinical utility and operational scalability, positioning us to better support the growing demand for accessible, non-invasive liver diagnostics and treatment, particularly in the management of MASLD and MASH at the point-of-care.' About Sonic Incytes Sonic Incytes is committed to enhancing patient care through innovative diagnostic solutions. The company's flagship product, Velacur™, equips physicians with an advanced liver imaging tool to help manage the growing epidemic of fatty liver disease. Velacur™ offers real-time, AI-guided quantification of the key markers for fatty liver disease: liver stiffness, attenuation and VDFF. With real-time results, a low up-front cost and AI guidance, Velacur™ makes liver imaging at the point-of-care affordable and accessible. For more information, visit ________________________________ 1 American Liver Foundation. (2025, June). Nonalcoholic fatty liver disease (NAFLD). American Liver Foundation 2 Le P, Tatar M, Dasarathy S, et al. Estimated Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease in US Adults, 2020 to 2050. JAMA Netw Open. 2025;8(1):e2454707. doi:10.1001/jamanetworkopen.2024.54707 3 Fishman, J., Kim, Y., Charlton, M.R. et al. Estimation of the Eligible Population For Resmetirom Among Adults in the United States for Treatment of Non-Cirrhotic NASH with Moderate-to-Advanced Liver Fibrosis. Adv Ther 41, 4172–4190 (2024). 4 Friedman SL. Fat, fibrosis, and the future: navigating the maze of MASLD/MASH. J Clin Invest. 2025 Apr 1;135(7):e186418. doi: 10.1172/JCI186418. PMID: 40166940; PMCID: PMC11957683. 5 Fishman J, Alexander T, Kim Y, Kindt I, Mendez P. A clinical decision support tool for metabolic dysfunction-associated steatohepatitis in real-world clinical settings: a mixed-method implementation research study protocol. J Comp Eff Res. 2024 Oct;13(10):e240085. doi: 10.57264/cer-2024-0085. Epub 2024 Sep 20. PMID: 39301878; PMCID: PMC11426282. 6 Gbadamosi, S. O., Evans, K. A., Brady, B. L., & Hoovler, A. (2025). Noninvasive tests and diagnostic pathways to MASH diagnosis in the United States: a retrospective observational study. Journal of Medical Economics, 28(1), 314–322. 7 Noureddin, M., Charlton, M. R., Harrison, S. A., Bansal, M. B., Alkhouri, N., Loomba, R., Sanyal, A. J., & Rinella, M. E. (2024). Expert panel recommendations: Practical clinical applications for initiating and monitoring resmetirom in patients with MASH/NASH and moderate to noncirrhotic advanced fibrosis. Clinical Gastroenterology and Hepatology, 22(12), 2367–2377. 8 Chen VL, Morgan TR, Rotman Y, Patton HM, Cusi K, Kanwal F, Kim WR. Resmetirom therapy for metabolic dysfunction-associated steatotic liver disease: October 2024 updates to AASLD Practice Guidance. Hepatology. 2025 Jan 1;81(1):312-320. doi: 10.1097/HEP.0000000000001112. Epub 2024 Oct 18. Erratum in: Hepatology. 2025 Apr 1;81(4):E133. 9 Honarvar, M., Lobo, J., Schneider, C., Klein, S., Smith, G. I., Loomba, R., Ramji, A., Hassanein, T., Yoshida, E. M., Pang, E., Curry, M. P., & Afdhal, N. H. (2024). Methods and validation of Velacur determined fat fraction in patients with MASLD. WFUMB Ultrasound Open, 2(2), Article 100061. Expand

FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE
FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE

Business Wire

time2 hours ago

  • Business Wire

FDA Grants 510(k) Clearance for Sonic Incytes' Velacur ONE

VANCOUVER, British Columbia--(BUSINESS WIRE)--Sonic Incytes Medical Corp, proudly announces that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for Velacur ONE™, its point-of-care ultrasound elastography device. Building on the success of its original model, Velacur™, Velacur ONE™ introduces an enhanced interface and features for improved portability and user experience. These improvements enable broader scalability to support Sonic Incytes' accelerated US and global expansion strategy. Velacur ONE™ measures attenuation, VDFF (Velacur Determined-Fat Fraction), and liver stiffness using 3D S-WAVE and aids in the management of chronic liver disease including MASH and MASLD. The launch of Velacur ONE™ marks a pivotal milestone for Sonic Incytes as we accelerate our US and global commercial expansion strategy. 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Current treatment guidelines for MASH recommend imaging-based elastography, such as Velacur™, to assess liver scarring (fibrosis) and fat content (steatosis). While ultrasound elastography is widely used, when it comes to treating patients with MASH, liver stiffness alone cannot be relied on to assess treatment response in the short term 7. The best predictor of treatment responses was a decrease in steatosis (identified as ≥30% reduction in MRI-PDFF) 8. VDFF, Sonic Incytes' proprietary algorithm that received FDA clearance in 2024, demonstrates a strong correlation (r = 0.85) with MRI-PDFF—the gold standard for liver fat measurement—and achieves an outstanding accuracy (AUC) of 95% of patients with more than 5% MRI-PDFF, defining the presence of hepatic steatosis 9. Velacur ONE™ combines this technology with a refined user interface, including B-mode imaging—enabling 3–4x higher reimbursement than non-imaging elastography—and an AI-based organ overlay feature to aid in liver localization, making it the only point-of-care device that estimates both liver stiffness and attenuation that correlates to MRI-PDFF 10. 'The launch of Velacur ONE™ marks a pivotal milestone for Sonic Incytes as we accelerate our US and global commercial expansion strategy,' said Barry Allen, CEO of Sonic Incytes. 'This next-generation device enhances clinical utility and operational scalability, positioning us to better support the growing demand for accessible, non-invasive liver diagnostics and treatment, particularly in the management of MASLD and MASH at the point-of-care. ' About Sonic Incytes Sonic Incytes is committed to enhancing patient care through innovative diagnostic solutions. The company's flagship product, Velacur™, equips physicians with an advanced liver imaging tool to help manage the growing epidemic of fatty liver disease. Velacur™ offers real-time, AI-guided quantification of the key markers for fatty liver disease: liver stiffness, attenuation and VDFF. With real-time results, a low up-front cost and AI guidance, Velacur™ makes liver imaging at the point-of-care affordable and accessible. For more information, visit ________________________________ 1 American Liver Foundation. (2025, June). Nonalcoholic fatty liver disease (NAFLD). American Liver Foundation 2 Le P, Tatar M, Dasarathy S, et al. Estimated Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease in US Adults, 2020 to 2050. JAMA Netw Open. 2025;8(1):e2454707. doi:10.1001/jamanetworkopen.2024.54707 3 Fishman, J., Kim, Y., Charlton, M.R. et al. Estimation of the Eligible Population For Resmetirom Among Adults in the United States for Treatment of Non-Cirrhotic NASH with Moderate-to-Advanced Liver Fibrosis. Adv Ther 41, 4172–4190 (2024). 4 Friedman SL. Fat, fibrosis, and the future: navigating the maze of MASLD/MASH. J Clin Invest. 2025 Apr 1;135(7):e186418. doi: 10.1172/JCI186418. PMID: 40166940; PMCID: PMC11957683. 5 Fishman J, Alexander T, Kim Y, Kindt I, Mendez P. A clinical decision support tool for metabolic dysfunction-associated steatohepatitis in real-world clinical settings: a mixed-method implementation research study protocol. J Comp Eff Res. 2024 Oct;13(10):e240085. doi: 10.57264/cer-2024-0085. Epub 2024 Sep 20. PMID: 39301878; PMCID: PMC11426282. 6 Gbadamosi, S. O., Evans, K. A., Brady, B. L., & Hoovler, A. (2025). Noninvasive tests and diagnostic pathways to MASH diagnosis in the United States: a retrospective observational study. Journal of Medical Economics, 28 (1), 314–322. 7 Noureddin, M., Charlton, M. R., Harrison, S. A., Bansal, M. B., Alkhouri, N., Loomba, R., Sanyal, A. J., & Rinella, M. E. (2024). Expert panel recommendations: Practical clinical applications for initiating and monitoring resmetirom in patients with MASH/NASH and moderate to noncirrhotic advanced fibrosis. Clinical Gastroenterology and Hepatology, 22(12), 2367–2377. 8 Chen VL, Morgan TR, Rotman Y, Patton HM, Cusi K, Kanwal F, Kim WR. Resmetirom therapy for metabolic dysfunction-associated steatotic liver disease: October 2024 updates to AASLD Practice Guidance. Hepatology. 2025 Jan 1;81(1):312-320. doi: 10.1097/HEP.0000000000001112. Epub 2024 Oct 18. Erratum in: Hepatology. 2025 Apr 1;81(4):E133. 9 Honarvar, M., Lobo, J., Schneider, C., Klein, S., Smith, G. I., Loomba, R., Ramji, A., Hassanein, T., Yoshida, E. M., Pang, E., Curry, M. P., & Afdhal, N. H. (2024). Methods and validation of Velacur determined fat fraction in patients with MASLD. WFUMB Ultrasound Open, 2(2), Article 100061. Expand

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