Rare autologous amniotic patch infusion performed in complicated triplet pregnancy; Mangaluru doctors intervene after fluid leak
MANGALURU: The medical team at Father Muller Medical College successfully executed a rare autologous amniotic patch infusion using the advanced AmnioSeal procedure in a complicated triplet pregnancy in a 40-year-old woman.
The patient was referred by the department of OBG for an anomaly scan. The scan revealed a dichorionic triamniotic triplet pregnancy, with one monochorionic pair sharing the same placenta. The following day, the patient presented with premature rupture of membranes (PV leak) from one of the monochorionic sacs. The patient was managed conservatively, but the slow leak continued, and the amniotic fluid level reached critically low levels.
Recognising the high risk of pregnancy loss, a novel regenerative approach, an autologous amniotic patch infusion to seal the leak and minimise immunogenic response, was suggested. This cutting-edge intervention involved harvesting the patient's own platelets through apheresis (a medical procedure that separates blood into its components), followed by a precisely regulated intra-amniotic infusion of autologous platelets and cryoprecipitate into the affected sac.
Sponsored Links
Sponsored Links
Promoted Links
Promoted Links
You May Like
Secure Your Child's Future with Strong English Fluency
Planet Spark
Learn More
Undo
The complex procedure was successfully carried out by the Fetal Medicine team led by Dr Muralidhar G.K, Dr Ram Shenoy, and Dr Prathima Prabhu, in close coordination with the obstetrics team of Dr Sujaya V Rao and Dr Joylene D'Almeida.
The team overcame several critical challenges, including critically low amniotic fluid volume, complicating sac entry, avoiding injury to fetal parts and the umbilical cord during the procedure, risk of fetal bradycardia during prolonged intrauterine handling, co-twin movements, increasing procedural complexity, and risk.
Despite these difficulties, the team completed the procedure with precision and care. Post-procedure monitoring has shown a favourable outcome, including the restoration of amniotic fluid, absence of infection, and continued fetal stability.
'This case represents a major step forward in regenerative fetal therapy,' said Dr Ram Shenoy, Professor and Head of the Department of Radiology, adding, 'Performing such a targeted intervention in a triplet pregnancy is exceedingly rare and no studies found to date.'
This procedure holds promise in preventing preterm birth and its associated complications. Meanwhile, the patient continues to remain under close observation.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Hans India
2 hours ago
- Hans India
Dy Mayor distributes books, uniforms to students
Hyderabad: With the schools reopening on Thursday, the Greater Hyderabad Deputy Mayor Mothe Srilatha Shoban Reddy distributed textbooks and uniforms provided by the state government among students of Government school in Tarnaka. This was under the Badi Bata 2025 programme. On this occasion, the Deputy Mayor highlighted various government schemes aimed at shaping the future of students. These include digital classrooms, fully equipped labs for science, mathematics, and English, vocational courses - binding, electrical work, tailoring, free mid-day meals, free uniforms and textbooks, free medical check-ups, free bus passes, scholarships for SC/ST and minority students, and computer classes for students from grades VI to X.
Time of India
17 hours ago
- Time of India
COVID-19: Isolation beds kept ready in Kalyan-Dombivli civic hospitals
Thane: Amid the recent rise in COVID-19 cases in Maharashtra , the Kalyan-Dombivli Municipal Corporation in Thane district has kept 15 isolation beds ready at two civic hospitals to meet any urgency, officials said on Thursday. Maharashtra reported 107 new COVID-19 cases on Wednesday, taking the total of viral infections detected in the state so far this year to 1,700, as per the public health department. Two more deaths of COVID-19 patients also were recorded in the last couple of days, taking the toll since January to 21, an official release on Wednesday said. Of the new infections, 34 were recorded in Mumbai, one in Thane district, seven in Thane Municipal Corporation limits, five in Navi Mumbai, one in Kalyan Municipal Corporation, four in Pune district, 44 in Pune Municipal Corporation, seven in Pimpri Chinchwad, one in Sangli, two in Sangli Municipal Corporation and one in Nagpur Municipal Corporation, it said. As part of COVID-19 preparedness , 10 isolation beds have been kept ready at the Bai Rukmini Bai Hospital and five at the Shastri Nagar Hospital , and RT-PCR and antigen testing kits are available, KDMC Commissioner Abhinav Goyal told reporters. "People should report symptoms promptly and not panic," he said. On monsoon preparedness, he said a 24x7 emergency control room is operational at the municipal headquarters, with deputy commissioner-level officers on night duty. Emergency rooms have also been activated in ward offices, with specially assigned multi-departmental teams. An NDRF team has already arrived to coordinate disaster response and awareness, the official said. Reaffirming the civic body's commitment to quality education, Goyal said the KDMC will launch five semi-English schools from the academic year 2025-26. "To ensure quality education, a guardian officer has been appointed for every municipal school," he added. The civic body also unveiled initiatives under the BaLA (Building as Learning Aid) method, introducing mural-based learning and improving school infrastructure, including repairs, furniture and timely distribution of books, uniforms and essentials. Under the "Nipun" programme, primary education will be prioritised, with digital quality monitoring through the Vinoba Bhave App and regular inspections by guardian officers, the civic body said.
Time of India
a day ago
- Time of India
Harvard doctor reveals two simple habits for a healthier liver
Liver health is finally in the spotlight, and honestly, it's about time. For the longest stretch, people only paid attention to their liver when binge-drinking or during a serious doctor's visit involving hepatitis. But now? From fatty liver concerns to detox advice and enzyme level checks, the liver is suddenly front and center—and for good reason. Non-alcoholic fatty liver disease (NAFLD) is on the rise, quietly becoming a global health issue. The kicker? You don't need to touch alcohol to have liver problems anymore. Unhealthy eating habits, excess sugar, a sedentary lifestyle, and stress are enough to mess it up. What's worse—most people don't even know their liver's struggling until things are already serious. View this post on Instagram A post shared by Saurabh Sethi (@ Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Secure Your Child's Future with Strong English Fluency Planet Spark Learn More Undo And let's not forget—your liver does way more than process alcohol. It's your body's detox champion, filtering toxins from medications, pollutants, processed food, and more. If your liver is under strain, your whole body feels it. From breakouts and hormone issues to fatigue—your liver may be behind the scenes of it all. Thanks to the wellness wave and growing focus on holistic health, people are now looking beyond visible muscles or calorie counts. They want to feel good from the inside out—and a healthy liver is key to that. Live Events What Dr. Saurabh Sethi has to say Popular on social media for his health insights, Dr. Saurabh Sethi recently explained how liver disease develops—starting from fatty liver, progressing to inflammation, and ultimately, cirrhosis if ignored. In his video, he highlighted two key strategies for maintaining liver health: Cutting back on alcohol Improving metabolic health Let's break them down. Your liver is a powerhouse, but it needs help Your liver is like the hardest-working employee in your body—it detoxes, stores energy, breaks down fats, and keeps your internal systems running smoothly. But today's lifestyle—marked by sugary snacks, lack of movement, and weekend drinking—is taking a toll. Alcohol is a known liver enemy, and not just in large quantities. Even moderate drinking, when consistent, can silently harm your liver. That's because when the liver breaks down alcohol, it produces a toxic byproduct—acetaldehyde—which causes inflammation and scarring. Left unchecked, this can progress to fatty liver, fibrosis, and eventually cirrhosis. The scary part? These changes often come without warning signs. The good news: Your liver can regenerate—but only if you stop stressing it. Reducing alcohol intake, even slightly, can give your liver space to heal and function better. The other culprit: Poor metabolic health Even without alcohol, your liver can suffer—especially when your metabolic health is off. Think high blood sugar, insulin resistance, belly fat—this combo can lead to non-alcoholic fatty liver disease (NAFLD), now a leading cause of liver damage globally. When your diet is overloaded with refined carbs and sugar, your liver stores the excess as fat. Pair that with low activity and poor sleep, and you've got a recipe for chronic liver stress. How to support your liver—The right way Forget expensive liver detox powders or week-long juice cleanses. Real liver care comes down to simple lifestyle shifts: Cut the sugar and processed carbs Be more active—even daily walking helps Eat real, whole foods Get enough sleep Maintain a healthy weight Even small improvements can pay off. Losing just 5–10% of your body weight can reduce liver fat. Better sleep reduces inflammation. Moving more boosts insulin sensitivity. It's all connected. [With TOI inputs]
