Bondi inquest hears GP told 'nothing' about attacker's mental state
Published 15 May 2025, 6:09 am
The regular general practitioner of Bondi Westfield attacker Joel Cauchi, says he had no information about potential signs of a psychotic relapse before he ended up killing half a dozen people at a shopping centre and being shot dead by police. These potential signs of relapse included a large number of suspicious notes being left around the house.
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ABC News
29 minutes ago
- ABC News
World-first living skin grown in Queensland laboratory
Scientists have successfully grown what they say is the world's most advanced human skin in a Queensland laboratory — and hope it could be used to study rare genetic skin disorders affecting thousands of Australians. Researchers at the University of Queensland's Fraser Institute used stem cells to create the human skin replica, which contains blood vessels, capillaries, hair follicles, layers of tissue and immune cells. Institute director Professor Kiarash Khosrotehrani said the skin organoids were developed over six years and could be transformative for skin grafts, wound healing and studying skin disorders. "We think that this is now opening completely new doors towards finding new treatments for a range of rare diseases that are affecting a lot of parents with sick children." Senior research fellow Dr Abbas Shafiee said it's a step up from previous skin models that contain a thin layer of skin and one cell type. "Having those vascular and immune components allows us to model diseases in the lab and hopefully develop new medicines to target them," he said. The researchers hope it can improve the study of a range of common skin disorders like psoriasis, atopic dermatitis and scleroderma, as well as rarer genetic diseases. "These organoid models that we have developed that have all the components of skin are now really going to open our eyes in terms of what's happening and how we can fix things," said Professor Khosrotehrani. The research could also help to improve skin grafts, which are vital for extensive burns, wounds or certain surgeries — although the researchers said that is still "down the track." Queensland has the highest rate of skin cancer in the world and more than 3,600 Queenslanders are diagnosed with melanoma every year. More than 350,000 non-melanoma skin cancers are treated annually, according to the QIMR Berghofer Medical Research Institute. "We always talk about burns and trauma injuries but what's much more common is actually the grafting that happens during skin cancer," Professor Khosrotehrani said. "What we're thinking is that with our skin organoids that are now vascularised, that substituted skin on a patient will actually have sensation because in our skin organoids we have nerves, it would have hair, it would have sweat glands." Allison Cowin is a professor of regenerative medicine at the University of South Australia and a researcher working on an antibody therapy for people suffering from epidermolysis bullosa (EB). EB is a rare genetic disorder that affects fewer than 1,500 Australians and causes skin to be fragile and blister easily. It's also known as the 'butterfly disease' because the skin of people with EB is so delicate it is likened to butterfly wings. Professor Cowin said the skin organoid has the potential to be a "useful stepping stone" in identifying what will work in the treatment of rare diseases like EB. "Being able to do it with their models would rapidly allow new drugs and new approaches to be taken in trials," she said. "You don't want to be testing things on those patients because that's just not fair." But Professor Cowin said it's important not to get too far ahead or give patients false hope. She noted it would be "really complicated" to move from the lab to putting skin grafts on human patients. "There's still a little way to go from the exciting results that they're getting," she said.
News.com.au
an hour ago
- News.com.au
5 Best Azelaic Acid Serums for Clear & Smooth Skin in 2025
We've uncovered the latest buzzy skincare ingredient and here's how you can use it for 'brighter and clearer' skin. These products are hand-picked by our team to help make shopping easier. We may receive payments from third parties for sharing this content and when you purchase through links in this article. Product prices and offer details are not assured, and should be confirmed independently with the retailer. Learn more There's a buzzy new skincare ingredient to hit the block – and it may just become your new favourite thing. While it's not new, people are only now recognising just how well azelaic acid can work to promote a softer, smoother complexion. According to Rachel McAdam, Head of Medical Relations at La Roche-Posay, azelaic acid is a 'naturally occurring acid, acting as a multifunctional ingredient'. So it actually sits in a different class to other exfoliating acids like AHAs or BHAs. Azelaic acid works hard to visibly improve skin texture and can even help reduce the appearance of redness or uneven skin tone. To help you on your quest to brighter skin, we've rounded up the best beauty buys to add azelaic acid into your routine. Our top pick? One launch from La Roche-Posay that's left shoppers totally shocked – 'it really works!' – on how well it supports a 'brighter and clearer' complexion. OUR TOP PICKS EDITOR'S PICKS: BEST AZELAIC ACID PRODUCTS La Roche-Posay Effaclar A.Z. Gel Cream What You Need To Know If you're new to the world of azelaic acid, the Effaclar A.Z. Gel Cream from La Roche-Posay is a great way to get started. The lightweight cream helps to refine skin texture and hydrate at the same time – and it's all thanks to its unique blend of azelaic acid, salicylic acid and hyaluronic acid. Perfectly formulated for adult blemish-prone skin, this cream promises to leave your complexion looking visibly smoother while also reducing the appearance of post-blemish marks. And it turns out the newest launch from the viral skincare brand La Roche-Posay is popular among shoppers too. Five-star rating reviewers said 'the hype is real' and 'it really works', adding that they've noticed their skin is 'brighter' and 'clearer' after using the gel cream consistently. What You Need To Know Paula's Choice offers a range of booster treatments that you can either use alone or alongside your favourite serum or moisturiser. This one is packed with 10 per cent azelaic acid, as well as salicylic acid and plant extracts to really focus on brightening and smoothing the skin. The multi-tasking formula is also lightweight, offering an oil-free gel-cream texture, so it's suitable for all skin types. Paula's Choice shoppers who gave the booster a five-star rating say it's made a 'noticeable difference' to their skin, even noting its made their skin look 'glowy and bright'. Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum What You Need To Know The world of K-Beauty serum is predominantly filled with hydrating, soothing and calming serums – and Anua's Azelaic Acid Serum is no exception. Formulated with 10 per cent azelaic acid, hyaluronic acid and a gentle calming complex of things like green tea leaf water and aloe leaf juice, this top-rated serum is the perfect pick for sensitive and irritated skin. And it seems like the Azelaic Acid 10 Hyaluron Redness Soothing Serum is popular with reviewers – one Amazon shopper called it 'one of the best serums I have used'. They continued, 'I'm seriously impressed … my skin feels smoother... and more even overall.' Azelaic Acid 20% w/w Serum, $35 (down from $59.99) at Helloskin Helloskin Azelaic Acid 20% w/w Serum $35 at Helloskin What You Need To Know This Aussie-made azelaic acid serum from Helloskin is a great pick if you need something that's going to address a whole bunch of skin concerns. Packed with a whopping 20 per cent azelaic acid to really help refine skin texture, it also has added niacinamide and saliyclic acid to even skin tone, as well as both ferulic acid and vitamin E to pump your skin with antioxidants. Described as 'confidence in a bottle', five-star rating reviewers also claim 'this serum has changed my life', noting it's 'helped smooth my skin texture'. What You Need To Know When it comes to treating and improving the look of blemish-prone skin, it's important to also think about the skin on your body. That's where these genius pads from Murad come in. Offering 45 easy-to-use pads that you can swipe over any body part, the formula is infused with a powerful blend of azelaic acid to calm and even skin tone, as well as salicylic acid to exfoliate and refine skin texture. Rave reviewers on the Murad website say these feel 'very gentle' on the skin, with another commenting on how they 'love the convenience and how simple they are to use. No overpowering smell!' WHAT TO LOOK FOR WHEN BUYING AN AZELAIC ACID SERUM When choosing azelaic acid serums to include in our list, we evaluated several factors: Price: You don't need to break the bank if you want to add an azelaic acid serum into your skincare routine. We've found picks from as little as $29 – bargain! Formula: Most of the picks on our list come in a serum form, and you want to make sure you find one that layers well with the rest of your products. Ingredients: When it comes to the formula, you need to decide what strength is best for you. 10 per cent azelaic acid is a good starting point, gradually increasing to 15-20 per cent as needed. HOW WE CHOOSE PRODUCTS With plenty of azelaic acid serums available, it's impossible to test every product out there. Our content is based on a range of different types of research – the team's first-hand experience with products, hours of research, scouring through pages of consumer reviews or information, and advice from experts we trust. We also spoke to Rachel McAdam, Head of Medical Relations at La Roche-Posay, to understand why your skincare routine can benefit from an azelaic acid serum. FREQUENTLY ASKED QUESTIONS WHAT'S THE BEST WAY TO USE AN AZELAIC ACID SERUM? It can always feel a little daunting using a new skincare product for the first time. Generally speaking, if you start slow and increase as needed, you should be good to go. Rachel recommends you 'apply an azelaic acid formulation after cleansing in the morning and/or at night. Products like La Roche-Posay's Effaclar A.Z. Gel-Cream have a gentle formula that can be used up to twice a day and suit even the most sensitive skin types.' She also adds, 'when using in the morning, always ensure you apply a sunscreen to finish your skincare routine.' WHAT ARE THE MAIN BENEFITS OF AN AZELAIC ACID SERUM? Azelaic acid is an exfoliating ingredient that can target a whole range of concerns. Rachel explains it's great for those concerned with the look of 'dark spots and uneven skin tone.' She also describes azelaic acid as a 'valuable ingredient for achieving clearer and more even-toned skin.' CAN AZELAIC ACID BE USED WITH OTHER SERUMS? According to Rachel, 'it will work well alongside serums containing gentle actives like niacinamide, vitamin C, hyaluronic acid. If using alongside serums containing a further dose of exfoliating actives like retinol, hydroxy acids such as glycolic, lactic and salicylic acid, a cautious and slow approach should be exercised.' Sign up to our newsletter for all the latest shopping tips and news. This article is for general information only. Always read the label and follow the directions for use. If symptoms persist, talk to your health professional.
The Australian
an hour ago
- The Australian
What the Facts: Argentica Therapeutics
What are strokes? How many people do they impact? And what are the limitations of current treatments? Host Tylah Tully is joined in this episode by Argenica Therapeutics (ASX:AGN) managing director Dr Liz Dallimore, who shares all about the devastating global impact of strokes and the company's innovative approach to treatment. Dallimore explains what happens in the brain during a stroke, why cases are rising worldwide, and the limitations of current treatments. She also explains how Argenica's neuroprotective drug works, which aims to protect brain cells and extend the treatment window for stroke patients; potentially transforming outcomes. With a Phase II trial nearing results, Argenica is positioning itself at the forefront of stroke therapy innovation. This video was developed in collaboration with Argenica Therapeutics, a Stockhead advertiser at the time of publishing. This video does not constitute financial product advice. You should consider obtaining independent advice before making any financial decisions.
