Palvella Therapeutics to Host Second Quarter 2025 Financial Results and Corporate Update Conference Call on August 14, 2025
Palvella management will host a conference call for investors at 8:30 a.m. ET on Thursday, August 14, 2025, to discuss financial results and provide a corporate update.
To access the live webcast of the call with slides, please click here or visit the "Events & Presentations" section of Palvella's website. To access the call by phone, please use this registration link, and you will be provided with dial in details. A replay of the webcast will be available approximately 2 hours after the conclusion of the call and archived for 90 days under the "Events & Presentations" section of the Company's website at www.palvellatx.com.
About Palvella Therapeutics
Founded and led by rare disease drug development veterans, Palvella Therapeutics, Inc. (Nasdaq: PVLA) is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies. Palvella is developing a broad pipeline of product candidates based on its patented QTORIN™ platform, with an initial focus on serious, rare genetic skin diseases, many of which are lifelong in nature. Palvella's lead product candidate, QTORIN 3.9% rapamycin anhydrous gel (QTORIN™ rapamycin), is currently being evaluated in the Phase 3 SELVA clinical trial in microcystic lymphatic malformations and the Phase 2 TOIVA clinical trial in cutaneous venous malformations. For more information, please visit www.palvellatx.com or follow Palvella on LinkedIn or X (formerly known as Twitter).
QTORIN™ rapamycin is for investigational use only and has not been approved or cleared by the FDA or by any other regulatory agency for any indication.
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Globe and Mail
10 minutes ago
- Globe and Mail
MediaCo Reports Second Quarter Net Revenue of $31.2 Million and First Half of 2025 Net Revenue of $59.3 Million
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Forward-Looking Statements This communication includes or incorporates forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended ('Exchange Act'). You can identify these forward-looking statements by our use of words such as 'intend,' 'plan,' 'may,' 'will,' 'project,' 'estimate,' 'anticipate,' 'believe,' 'expect,' 'continue,' 'potential,' 'opportunity' and similar expressions, whether in the negative or affirmative. Such forward-looking statements, which speak only as of the date hereof, are based on managements' estimates, assumptions and beliefs regarding our future plans, intentions and expectations. We cannot guarantee that we will achieve these plans, intentions or expectations. All statements regarding our expected financial position, business, results of operations and financing plans are forward-looking statements. Actual results or events could differ materially from the plans, intentions or expectations disclosed in the forward-looking statements we make. We have included important facts in various cautionary statements in this communication that we believe could cause our actual results to differ materially from forward-looking statements that we make. The forward-looking statements do not reflect the potential impact of any future acquisitions, mergers or dispositions. We undertake no obligation to update or revise any forward-looking statements because of new information, future events or otherwise. You should not place undue reliance on these forward-looking statements, which speak only as of the date of this release. For more details on factors that could affect these expectations, please see MediaCo's other filings with the Securities and Exchange Commission. Definitions and Disclosures Regarding Non-GAAP Financial Information We define Adjusted EBITDA as consolidated Operating loss adjusted to exclude restructuring expenses, business combination transaction costs, unusual and non-recurring expenditures and non-cash compensation included within operating expenses, as well as the following line items presented in our Statements of Operations: Depreciation and amortization, Loss on disposal of assets, change in fair value of warrant shares liability and Other income. Alternatively, Adjusted EBITDA is calculated as Net loss, adjusted to exclude Provision for income taxes, Interest expense, net, Depreciation and amortization, Loss on disposal of assets, Change in fair value of warrant shares liability, Other income, and Other adjustments. We use Adjusted EBITDA, among other measures, to evaluate the Company's operating performance. This measure is among the primary measures used by management for the planning and forecasting of future periods, as well as for measuring performance for compensation of executives and other members of management. We believe this measure is an important indicator of our operational strength and performance of our business because it provides a link between operational performance and operating income. It is also a primary measure used by management in evaluating companies as potential acquisition targets. We believe the presentation of this measure is relevant and useful for investors because it allows investors to view performance in a manner similar to the method used by management. We believe it helps improve investors' ability to understand our operating performance and makes it easier to compare our results with other companies that have different capital structures or tax rates. In addition, we believe this measure is also among the primary measures used externally by our investors, analysts and peers in our industry for purposes of valuation and comparing our operating performance to other companies in our industry. Since Adjusted EBITDA is not a measure calculated in accordance with GAAP, it should not be considered in isolation of, or as a substitute for, operating loss or net loss as an indicator of operating performance and may not be comparable to similarly titled measures employed by other companies. Adjusted EBITDA is not necessarily a measure of our ability to fund our cash needs. Because it excludes certain financial information compared with operating loss and compared with consolidated net loss, the most directly comparable GAAP financial measures, users of this financial information should consider the types of events and transactions which are excluded. For a reconciliation of these non-GAAP financial measurements to the GAAP financial results cited in this news announcement, please see the supplemental tables at the end of this release. About MediaCo Holding Inc. MediaCo Holding Inc. (Nasdaq: MDIA) is a diverse-owned, multi-platform media company serving multicultural audiences across the U.S. Through a network of iconic brands—including Hot 97, WBLS, EstrellaTV, Estrella News, Que Buena Los Angeles and the Don Cheto Radio Network—MediaCo reaches over 20 million people monthly via television, radio, digital, and streaming platforms. The company's innovative and culturally resonant content spans music, news, and entertainment across major local and national markets. More info at Three Months Ended June 30, Change (Dollars in thousands) 2025 2024 $ % NET REVENUES $ 31,245 $ 26,202 5,043 19 OPERATING EXPENSES: Operating expenses 34,774 34,647 127 — Corporate expenses 1,554 3,445 (1,891 ) (55 ) Depreciation and amortization 1,697 1,431 266 19 Loss on disposal of assets 5 5 — N/A Total operating expenses 38,030 39,528 (1,498 ) (4 ) OPERATING LOSS (6,785 ) (13,326 ) 6,541 (49 ) OTHER INCOME (EXPENSE): Interest expense, net (3,855 ) (3,782 ) (73 ) 2 Change in fair value of warrant shares liability — (31,027 ) 31,027 N/A Other income 2,119 10 2,109 21,090 Total other expense (1,736 ) (34,799 ) 33,063 (95 ) LOSS BEFORE INCOME TAXES (8,521 ) (48,125 ) 39,604 (82 ) PROVISION FOR INCOME TAXES 279 182 97 53 NET LOSS $ (8,800 ) $ (48,307 ) 39,507 (82 ) MEDIACO HOLDING INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) Six Months Ended June 30, Change (Dollars in thousands) 2025 2024 $ % NET REVENUES $ 59,275 $ 32,908 26,367 80 OPERATING EXPENSES: Operating expenses 63,986 41,297 22,689 55 Corporate expenses 3,147 6,835 (3,688 ) (54 ) Depreciation and amortization 3,466 1,564 1,902 122 Loss on disposal of assets 144 5 139 2,780 Total operating expenses 70,743 49,701 21,042 42 OPERATING LOSS (11,468 ) (16,793 ) 5,325 (32 ) OTHER INCOME (EXPENSE): Interest expense, net (7,609 ) (3,918 ) (3,691 ) 94 Change in fair value of warrant shares liability — (31,027 ) 31,027 N/A Other income 2,230 20 2,210 11,050 Total other expense (5,379 ) (34,925 ) 29,546 (85 ) LOSS BEFORE INCOME TAXES (16,847 ) (51,718 ) 34,871 (67 ) PROVISION FOR INCOME TAXES 559 266 293 110 NET LOSS $ (17,406 ) $ (51,984 ) 34,578 (67 ) MEDIACO HOLDING INC. NON-GAAP FINANCIAL MEASURES RECONCILIATIONS OF NET LOSS TO EBITDA AND ADJUSTED EBITDA (1) AND NET LOSS MARGIN TO ADJUSTED EBITDA MARGIN (1) Three Months Ended June 30, Six Months Ended June 30, (Dollars in thousands) 2025 2024 2025 2024 Net revenues $ 31,245 $ 26,202 $ 59,275 $ 32,908 Net Loss $ (8,521 ) $ (48,125 ) $ (17,406 ) $ (51,984 ) % Margin (28 )% (184 )% (29 )% (158 )% Provision for income taxes 279 182 559 266 Interest expense, net 3,855 3,782 7,609 3,918 Depreciation and amortization 1,697 1,431 3,466 1,564 EBITDA $ (2,690 ) $ (42,730 ) $ (5,772 ) $ (46,236 ) Loss on disposal of assets 5 5 144 5 Change in fair value of warrant shares liability — 31,027 — 31,027 Other income (2,119 ) (10 ) (2,230 ) (20 ) Other adjustments 6,595 6,486 10,776 10,725 Adjusted EBITDA (1) $ 1,791 $ (5,222 ) $ 2,918 $ (4,499 ) % Margin (1) 6 % (20 )% 5 % (14 )% (1) We define Adjusted EBITDA as consolidated Operating loss adjusted to exclude restructuring expenses, business combination transaction costs, unusual and non-recurring expenditures and non-cash compensation included within operating expenses, as well as the following line items presented in our Statements of Operations: Depreciation and amortization, Loss on disposal of assets, change in fair value of warrant shares liability and Other income. Alternatively, Adjusted EBITDA is calculated as Net loss, adjusted to exclude Provision for income taxes, Interest expense, net, Depreciation and amortization, Loss on disposal of assets, Change in fair value of warrant shares liability, Other income, and Other adjustments. We define Adjusted EBITDA margin as Adjusted EBITDA as a percentage of net revenue. We use Adjusted EBITDA and Adjusted EBITDA margin, among other measures, to evaluate the Company's operating performance. These measures are among the primary measures used by management for the planning and forecasting of future periods, as well as for measuring performance for compensation of executives and other members of management. We believe these measures are an important indicator of our operational strength and performance of our business because they provide a link between operational performance and operating income. They are also primary measures used by management in evaluating companies as potential acquisition targets. We believe the presentation of these measures is relevant and useful for investors because it allows investors to view performance in a manner similar to the method used by management. We believe they help improve investors' ability to understand our operating performance and make it easier to compare our results with other companies that have different capital structures or tax rates. In addition, we believe these measures are also among the primary measures used externally by our investors, analysts and peers in our industry for purposes of valuation and comparing our operating performance to other companies in our industry. Since Adjusted EBITDA and Adjusted EBITDA margin are not measures calculated in accordance with GAAP, they should not be considered in isolation of, or as a substitute for, operating loss or net loss, or net loss margin as indicators of operating performance and may not be comparable to similarly titled measures employed by other companies. Adjusted EBITDA and Adjusted EBITDA margin are not necessarily measures of our ability to fund our cash needs. Because they exclude certain financial information compared with operating loss, consolidated net loss, and consolidated net loss margin, the most directly comparable GAAP financial measures, users of this financial information should consider the types of events and transactions which are excluded.
Globe and Mail
33 minutes ago
- Globe and Mail
Did Disney Just Win the Streaming Wars? Read About CEO Bob Iger's Huge Announcement Here.
Key Points Disney's theme parks were its main growth driver in the third quarter. Disney is merging Disney+ and Hulu into one app, which it expects to provide a better experience for users and greater opportunities for advertising for Disney. The new ESPN streaming channel is launching Aug. 21 and ESPN is acquiring the NFL network. 10 stocks we like better than Walt Disney › Iconic entertainment brand Disney (NYSE: DIS) had some exciting news for investors this week. The company reported earnings for the fiscal 2025 third quarter (ended June 28) and they were mediocre. But it was the company updates that stole the show, and it looks like Disney is getting into a better position in streaming. Let's see what's happening. No other experience like it Disney is an entertainment giant with many exclusive assets that serve as a strong moat. Although there are other theme parks in the world, there's nothing quite like the magic of the Disney experience, which brings together loved franchises and characters that fans feel connected to. All of Disney's segments work together, with the content and characters unifying all the parts. But Disney's theme parks are a complete business. They were a standout in the third quarter, driving total revenue growth of 2% year over year with an 8% increase, and driving overall profitability and an earnings beat with a 22% increase in operating income. That was important over the past few months, since streaming is still finding its footing and linear networks are still in decline. Disney+ added 1.8 million new subscribers in the quarter, only 1% more than last year, and streaming operating income increased about 5%. However, CEO Bob Iger provided some massive news about streaming that could positively change Disney's trajectory. ESPN, NFL, and Hulu There were two major announcements related to streaming that Iger gave on the earnings call. One was the integration of Hulu into Disney+, with both available through a single app. This offers greater selection and personalization options for viewers, as well as more engagement, lower churn, higher margins, and improved advertising opportunities for Disney. It puts the two channels together on one tech platform, which is easier and cheaper to run, and creates the potential for advertising packages that weren't available in the previous format. Down the line, Iger expects this to result in greater price elasticity and bundling opportunities. The second streaming update caught a lot more attention in the market, and that's the launch of the new ESPN+ on Aug. 21 along with a new partnership between ESPN and the National Football League (NFL). The ESPN+ streaming platform has been a work in progress for several years as Disney has tried tried to figure out what to do with it. It's an important element of the company's cable networks strategy, but it also needs to offer something unique to streaming viewers. The new ESPN streaming site will offer personalized features, game stats, fantasy sports, and other special elements not available on the cable network. Subscribers to the full Disney+, Hulu, and ESPN bundle will be able to view content directly on the Disney+ app, further unifying the platform. As part of its new streaming era, ESPN is acquiring the NFL network and some media assets, including highlight reels on social media sites and interactive platforms. It will also offer the NFL's Red Zone channel to premium subscribers. The NFL is taking a 10% stake in ESPN in return. This could have broader implications in the world of sports, impacting player salaries and the relationship with the players' union, and it will have to meet regulatory approval. But it's a big win for Disney as it carves out ESPN's place in the streaming world. Is Disney winning the streaming wars? I wouldn't say this means Disney is winning the streaming wars. Disney's streaming business is still trying to keep up with Netflix, which has truly demonstrated spectacular performance in the face of an onslaught of new streaming companies over the past few years. It still has more subscriptions than Disney, although it stopped reporting subscription numbers at the end of 2024, and it has more revenue than Disney's streaming business. It's also growing faster and has a wide operating margin of 31.5%. Disney has an unparalleled content library, but streaming only recently became profitable and it's still figuring out how to make the business work best. The new updates are exciting for Disney shareholders, and Disney's streaming business is well positioned to keep growing and create value for the company. Should you invest $1,000 in Walt Disney right now? Before you buy stock in Walt Disney, consider this: The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Walt Disney wasn't one of them. The 10 stocks that made the cut could produce monster returns in the coming years. Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you'd have $653,427!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you'd have $1,119,863!* Now, it's worth noting Stock Advisor's total average return is 1,060% — a market-crushing outperformance compared to 182% for the S&P 500. Don't miss out on the latest top 10 list, available when you join Stock Advisor. 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