Three NYC hospitals were just ranked among the nation's best
Mount Sinai Hospital, NYU Langone and NewYork-Presbyterian-Columbia and Cornell were all recognized for their high-quality care across a wide range of specialties, from heart surgery to neurology to pediatric care. They also ranked as the top three hospitals in the state, making New York City officially the best place to get patched up.
NYU Langone pulled off something no other hospital in the country did this year: it snagged more No. 1 specialty rankings than anyone else. That includes top marks in neurology, cardiology, pulmonology and geriatric care. So yeah, they're kind of a big deal.
Not to be outdone, NewYork-Presbyterian made the Honor Roll for the 22nd straight year, with 12 specialties landing in the national Top 10. And Mount Sinai also cracked the list thanks to strong showings in 12 adult specialties and three pediatric ones, plus the kind of science-first, patient-centered approach that earned them a glowing shout-out from their CEO.
The rankings are based on patient outcomes, specialty performance and behind-the-scenes metrics that make healthcare nerds swoon. It's a way for patients to figure out where to go when things get serious—and for hospitals to flex a little.
Other local notables: Montefiore Einstein in the Bronx and Lenox Hill Hospital both placed in the state's top five and 11 NYC Health + Hospitals locations made the broader 'Best Hospitals' list.
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Time Out
31-07-2025
- Time Out
Three NYC hospitals were just ranked among the nation's best
File under: actually good news. Three New York City hospitals just landed spots on U.S. News & World Report's annual Honor Roll, a coveted list that names the top 20 medical centers in the country. And no surprise here—they're all heavy hitters. Mount Sinai Hospital, NYU Langone and NewYork-Presbyterian-Columbia and Cornell were all recognized for their high-quality care across a wide range of specialties, from heart surgery to neurology to pediatric care. They also ranked as the top three hospitals in the state, making New York City officially the best place to get patched up. NYU Langone pulled off something no other hospital in the country did this year: it snagged more No. 1 specialty rankings than anyone else. That includes top marks in neurology, cardiology, pulmonology and geriatric care. So yeah, they're kind of a big deal. Not to be outdone, NewYork-Presbyterian made the Honor Roll for the 22nd straight year, with 12 specialties landing in the national Top 10. And Mount Sinai also cracked the list thanks to strong showings in 12 adult specialties and three pediatric ones, plus the kind of science-first, patient-centered approach that earned them a glowing shout-out from their CEO. The rankings are based on patient outcomes, specialty performance and behind-the-scenes metrics that make healthcare nerds swoon. It's a way for patients to figure out where to go when things get serious—and for hospitals to flex a little. Other local notables: Montefiore Einstein in the Bronx and Lenox Hill Hospital both placed in the state's top five and 11 NYC Health + Hospitals locations made the broader 'Best Hospitals' list.
NBC News
11-07-2025
- NBC News
Premenstrual disorders may indicate a higher risk for heart disease, study finds
Premenstrual disorders are associated with a higher risk of developing cardiovascular disease, a large, long-term study has found. New research analyzing patient health data from more than 3 million women in Sweden over a 20-year period found that those who were diagnosed with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) had an 11% higher risk of developing cardiovascular disease at some point, compared to women who did not have a diagnosis. Younger women who experienced a premenstrual disorder before age 25 had an even stronger risk of developing heart disease, 24%. Heart disease is the leading cause of death in women in the U.S. 'It's another reminder of taking care of your cardiovascular health when you're young and not waiting until you're in your 50s or later,' Elizabeth Bertone-Johnson said, study co-author and professor of epidemiology at the University of Massachusetts-Amherst. In order to be diagnosed with PMS or the more intense PMDD, symptoms such as mood swings, fatigue, cramping and food cravings need to be 'bad enough' to be rated as 'moderate' or 'severe,' or have a significant impact on a patient's ability to function, Bertone-Johnson said. The researchers analyzed subtypes of cardiovascular disease, including heart failure, arrhythmias and irregular heartbeat. An arrhythmia occurs when the heart's electrical signals misfire, making the heart beat too quickly or too slowly. Arrhythmias and ischemic heart disease, damage caused by plaque which has built up in the coronary arteries, showed the strongest associations with PMS and PMDD. Although the research did not study the possible reasons behind the link, Bertone-Johnson and other experts believe that premenstrual disorders might indicate other underlying physiological conditions. 'Eventually it will show up as cardiovascular disease, but before that, it shows up in premenstrual symptoms,' Bertone-Johnson said. These conditions can include inflammation and alteration of the renin-angiotensin-aldosterone system — a hormonal system that regulates blood pressure, Dr. Nieka Goldberg, a cardiologist who specializes in women's health at NYU Langone, said. These inflammatory changes can lead to an increased buildup of plaque around the heart's arteries — increasing the risk of heart disease. Goldberg was not involved in the new research. Even accounting for other cardiovascular risk factors such as smoking, weight, medication usage and some pre-existing conditions, women who had been diagnosed with a premenstrual disorder were more likely to develop heart problems. Researchers in Sweden also analyzed pairs of sisters as a way of accounting for genetic and environmental factors. There are limitations to the research. Bertone-Johnson said they looked only at women who had a clinical diagnosis of a premenstrual disorder and, because the population was based in Sweden, the patients were likely mostly white. Dr. Priya Jaisinghani, an endocrinologist at NYU Langone, thinks there should be more focus on women's risk factors for heart disease, which can include reproductive, hormonal and metabolic conditions. This study as well as others suggest a link between PMS and/or PMDD and hypertension, or high blood pressure. Still, high blood pressure is often underdiagnosed in women, according to the Office of Women's Health. Goldberg said that one of the most important implications of this study is how it may pave the way for diagnosis of cardiovascular disease in younger patients. 'This is a great step to early identification of women at risk for heart disease earlier in life,' she said. 'Although the mechanism for heart disease risk in premenstrual disorders will need further study, it is important for doctors to get a complete menstrual history, including the presence of PMD in their patients.'
Daily Mail
30-06-2025
- Daily Mail
Scientists find possible cure for diseases that impacts 10 million Americans in groundbreaking study
Scientists believe they might have found a cure for diabetes and other debilitating autoimmune diseases off the back of a groundbreaking new study. Researchers at NYU Langone Health, the Chinese Academy of Sciences, and Zhejiang University looked at why the body's defense mechanism goes haywire and turns against us, leaving a trail of incurable, life-changing diseases in its wake. Called autoimmune disorders, these include type 1 diabetes (where the rogue immune response damages insulin-producing cells in the pancreas), multiple sclerosis (MS, where the immune system destroys the protective coating around nerves that control sensation and movement – causing weakness and immobility) and hepatitis (where the immune system mistakenly attacks the liver cells, causing inflammation and damage). Together, these diseases affect more than four million Americans, but there are many other autoimmune disorders impacting millions more. Many patients end up on a lifelong cocktail of potent drugs that can reduce the worst of the symptoms but can have unpleasant side-effects – steroids, for example, can cause swelling, weight gain and osteoporosis. But new research suggests a type of treatment – called LAG-3/TCR Bispecific T cell Silencer or BiTS – could potentially stop all of these incurable disorders in their tracks by 'resetting' the immune system so it ceases its attacks on healthy tissue. Some experts predict it could be one of the biggest advances in treatment for decades. T-cells are a type of white blood cell that play a crucial role in the immune system, patrolling the body, including the bloodstream, to identify and destroy harmful cells and organisms. But sometimes they can struggle to differentiate between healthy cells and those that cause illness or disease, such as cancer or autoimmune conditions, leading the t-cells to mistakenly attack healthy tissue. One way around this is to tinker with T-cells by exposing them to a drug that alters their DNA, so they produce a protein called chimeric antigen receptor (CAR). This protein can more easily detect cancer cells that express the target antigen and destroy them. Once a T-cell becomes a CAR T-cell, it's reproduced in large numbers in the lab and injected a few weeks later back into the patient's body to fight cancer cells. But treatments focused on T-cells have been elusive because blocking their action broadly weakens the immune system and creates risk for infections and cancer. CAR T-cell therapy can also have serious effects on the nervous system, leading to a condition known as immune effector cell-associated neurotoxicity syndrome (ICANS). This can result in symptoms such as headaches, confusion, agitation, seizures and trouble speaking. However, the new research in mice published online in the journal Cell, reveals how a newly-designed antibody could help shut down T-cells in a more effective way and prevent these harmful side effects. The study results are based on the presence of T-cell receptors (TCRs) and checkpoints. TCRs are turned on by the body's own proteins in autoimmune diseases. Checkpoints like LAG-3 are also turned on by specific signaling partners, but when this occurs they suppress the T-cell's activity. This means the T cell's ability to attack other cells, such as cancer cells, is reduced. By introducing the antibody, it helped to prevent T-cells from damaging the body, focused on regulating their activity and supported the body's natural immune defenses. This approach is being explored and used in the treatment of various autoimmune diseases. In autoimmune models of hepatitis, the team's BiTS treatment reduced T cell infiltration and liver damage. They also treated mice prone to develop multiple sclerosis with short-term, preventive BiTS prior to the onset of disease symptoms, and they reported that BiTS-treated mice had reduced disease by a standard measure. 'Our study... may foster more proximity-based, spatially-guided therapeutic designs like BiTS as immunotherapy for other human diseases,' said co-first author Jia You, a research scientist in Dr. Wang's lab. 'Our findings reveal an intricate mechanism that enables a careful treatment approach to T-cell driven autoimmune diseases, which currently lack effective immunotherapies,' said co-senior study author Dr Jun Wang, assistant professor in the Department of Pathology at NYU Grossman School of Medicine.
