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Tiny tyrannosaur species discovered in Mongolia

Tiny tyrannosaur species discovered in Mongolia

Yahooa day ago

A new species of dinosaur has been discovered, which scientists say shows how tyrannosaurs evolved from smaller predators the size of a horse.
The 'Dragon Prince', whose bones were found in a Mongolian museum, is thought to be about 20 million years older than the Tyrannosaurus Rex and provides a 'missing link' in the evolution of the apex predators.
The skeleton of the Khankhuuluu Mongoliensis demonstrates where the T-Rex got its vicious bite, researchers who 'rediscovered' the species said.
'We see features in its nasal bone that eventually gave tyrannosaurs those very powerful bite forces,' said Jared Voris, from the University of Calgary, the researcher who found the bones.
The fossils were initially found in the early 1970s, but at the time were misidentified as belonging to a different tyrannosaur, Alectrosaurus.
The bones were put away in a drawer at the Institute of Palaeontology of the Mongolian Academy of Sciences in the capital Ulaanbaatar, until they were re-discovered by then-PhD student Mr Voris.
He was handed two plastic tubes full of bones while visiting the institute – and eventually found the fossils were partial skeletons of two different dinosaurs from a new species.
Darla Zelenitsky, a palaeontologist from the University of Calgary, said: 'It is quite possible that discoveries like this are sitting in other museums that just have not been recognised.'
The skeleton shows that the 'Dragon Prince' was about four metres long and weighed only 750kg, according to the findings, published in the academic journal Nature.
An adult T-Rex is believed to have weighed eight times as much.
'They were these really small, fleet-footed predators that lived in the shadows of other apex predatory dinosaurs,' said Dr Voris.
'This discovery shows us that, before tyrannosaurs became the kings, they were princes,' said Zelenitsky.
The finding is considered a 'transitional' fossil and has helped clarify the evolution of the tyrannosaur family, which was 'really messy previously,' said Dr Zelenitsky.
'What makes them so important is their age,' said Stephen Brusatte, a palaeontologist at the University of Edinburgh who was not involved in the study. 'They are about 86 million years old, a good 20 million years older than T-Rex. It has been a frustrating gap in the record.'
The discovery also helps to paint the migration patterns of the tyrannosaurs.
They show that T-Rex's direct ancestors probably migrated from Asia to North America across a land bridge that used to connect Siberia and Alaska 85 million years ago, Dr Zelenitsky said.
Tyrannosaurs then evolved in North America and remained there for the next several million years, she said.
'As the many tyrannosaur species evolved on the continent, they became larger and larger,' said Dr Zelenitsky.
The records are incomplete so scientists are unsure of what happened in Asia 80 million years ago. However, the Khankhuuluu may have later been replaced by larger, more dominant, tyrannosaurs.
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These Hamster Dads Are a Cut above the Rest
These Hamster Dads Are a Cut above the Rest

Scientific American

time8 hours ago

  • Scientific American

These Hamster Dads Are a Cut above the Rest

This Father's Day, we're celebrating the unusually involved Djungarian hamsters dads By edited by Fonda Mwangi Rachel Feltman: For Scientific American 's Science Quickly, I'm Rachel Feltman. Parental care is costly. It uses up precious time, energy and resources—and in the animal world, it's usually the moms who bear the brunt of it. For most mammals, the concept of fatherhood begins and ends at conception. So what drives a father to defy evolutionary norms? Today's episode celebrates the superparent skills of a surprising—and adorable—little critter. Our guide for this Father's Day Friday Fascination is Elah Feder, a freelance audio producer, editor and journalist. Here's Elah now. On supporting science journalism If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today. Elah Feder: In mammals, good dads are the exception. Male leopards, bears, orcas—they have a habit of toddling off after mating and leaving the mothers to raise the kids. So when you come across a mammal species with active, doting dads—dads who actually matter for their kids' survival—you pay attention. And one of the most extreme cases of good fatherhood can be found in a dwarf hamster that lives in the cold, dry semideserts of Russia, China and Mongolia: Phodopus campbelli, aka the Djungarian hamster. Campbelli males and females raise their kids in burrows underground. And when the first litter of pups arrive, the dads get to work right away. Katherine Wynne-Edwards: They will be very close by during the birth. Feder: Katherine Wynne-Edwards is a professor of veterinary medicine at the University of Calgary [in Alberta]. It took her a while to figure out exactly what these male hamsters were doing. But then she saw it: they were acting as midwives, physically delivering the babies. Wynne-Edwards: Actually getting film of a male using his four paws to pull the head of a neonate out of the birth canal was extraordinary. Feder: After the pups are born, the dad carries each one to a warm nest inside the burrow. Wynne-Edwards: And then he would spin it around, clean off its membranes ... and orient the face up and lick the nostrils and the mouth. Some of these pups are born pretty blue. And once the male has licked those nostrils, there's a flush of red, and we're back to what we call pinkies, little rodent babies. Feder: Katherine first encountered these hamsters in the early 1980s, back when she was a grad student. Wynne-Edwards: People really didn't know about them at all. They are native to the steppes of central Asia, which is, even by Canadian standards, an underpopulated part of the Earth. And so we really knew very little about them. Feder: So Katherine's adviser was like, 'Here, figure out everything you can about this species.' And what was immediately obvious was that they were stacked with adaptations for cold weather—adaptations that happened to make them extra cute. Wynne-Edwards: Let's be honest: they look like a windup toy. They're fluffy; they're really remarkably spherical; their tail is very short and barely protrudes from the rest of their fur. Their ears are relatively short and actually do even have hair on them, which many rodents don't, um, and can be folded down. Feder: All great ways to conserve heat in a place where temperatures can drop as low as –50 degrees Celsius [–58 degrees Fahrenheit]. But what made these hamsters really interesting was this biparental care—with both mother and father involved in raising the kids. Make no mistake—the mother is still doing the heavy lifting. She nurses the pups, which means giving up precious water and nutrients, but the father will take turns sitting on the pups, keeping them warm, returning them to the nest if they wander off. And when the mother weans them, the father is the one who sticks around for a few more days and feeds them seeds from his cheek pouches so they don't go wandering off from the burrow before they're ready. And the question is: Why? Most mammals—in fact, most animals in general—grow up just fine without dads. Nick Royle: Most care across different taxa is female-only care. Feder: Nick Royle is an associate professor of behavioral and evolutionary ecology at the University of Exeter in England. He says if we look beyond mammals, lots of animals don't have maternal care either. When the kids hatch, they're on their own. Royle: Parental care in general is quite rare. So only 3 percent of reptile families have parental care, for example. It's rare in invertebrates, but it is quite well developed, obviously, in things like ants and termites and beetles. Feder: From an evolutionary perspective, if you can make some offspring, and they thrive with no help from you, that's a win. You can keep your food for yourself, go off and reproduce again and spread more of your genes. On the other hand, if your offspring flounder and die without your support, your genes are not going to get very far. Royle: You typically get parental care evolving when the benefits outweigh those costs. Feder: In mammals, at least those who haven't invented baby formula, maternal care is essential. Newborns depend on milk for survival, so the costs of not nursing your offspring are very high. But for male mammals, the evolutionary calculation is a bit different. Having more mates means potentially having a lot more offspring. So although sticking around to feed your existing offspring or defend them from predators or teach them cool life skills, even though all of that might boost survival rates, males have to weigh that against lost mating opportunities. None of this is conscious, of course. These are just the evolutionary pressures shaping their behavior. In any case, as a result, in mammals ... Royle: There's various estimates, but up to 10 percent of mammalian species have males caring with females, and then most of the rest of the care is female-only care. Feder: So what's going on with these mammal species where dads are involved? When does active fatherhood become a winning evolutionary strategy? So let's take a look at these hamsters. First, we know that in these hamsters, Phodopus campbelli, pups do not fare well without their dads. In one study, Katherine found that mated pairs successfully raised 95 percent of their pups to adulthood. But when the male was removed, only half made it. And it wasn't about how much food they were getting. These studies were done in the lab, where plenty of food was provided. And it actually wasn't males' midwifery work either, helpful as that is— because, at least in the lab, females successfully gave birth even if they were alone. Instead the researchers found that the need for a male had a lot to do with temperature. Wynne-Edwards: The worst thing that can happen to a [ P. ] campbelli mum is that she's in a warm environment. Feder: These hamsters, being so well adapted to conserve heat, they're prone to overheat, especially if they're sitting day after day in a nest, nursing pups that are getting better and better at thermoregulating each day. Wynne-Edwards: The pups become more of a problem later because they're too hot. Feder: When solitary females were held at a comfortable 18 degrees Celsius, they were actually pretty successful. More than 90 percent of their pups survived without a dad present. But if it got even a few degrees hotter, suddenly male presence mattered a whole lot for pup survival and for growth. So why would that be? Well, Katherine found that males help the females regulate their own temperature. Females go for walks away from the nest to cool off. The hotter the temperature in the lab, the longer these cool-down walks are. For the mom, this is essential, but it's not great for the pups. They start to lose heat—and water, too— unless there's someone else there to sit on them and keep things nice and warm and humid, aka another parent. So ultimately, it seems like these dads are a product of evolving in a superharsh environment. In a place this cold, it's just hard for a single parent to retain heat and raise their kids without overheating. In fact, it's often the case that harsh environments tip the scales in favor of active fathers. Harsh environments can just mean that offspring need more help to grow up, selecting for more parental care in general. And we can actually see this play out in this hamster's very close relative, Phodopus sungorus, also known as the Siberian hamster. [ P.] sungorus lives right across a mountain range from our hamsters, [ P.] campbelli. Where they live, it's also a harsh environment but not quite as harsh. And in[ P.] sungorus the fathers are often—but not always—involved in the care of offspring. And when they are, they're not quite as attentive as [ P.] campbelli dads. Katherine has conducted experiments in the lab, where she'll remove a hamster pup from a nest and plop it in a far corner of its cage. Wynne-Edwards: The male—if the female is not there—the male will leave the nest, go to the pup, pick it up, bring it back to the nest and just sit down on it again. Feder: And in our star hamsters, [ P.] campbelli, the male will rush over right away, wasting no time. But in their close relative, [ P.] sungorus, the males respond, too, but they take more than twice as long to go over to the pup. And then, more than half the time, they don't even pick it up. So a harsh environment is one explanation for why [ P.] campbelli hamster dads are so devoted. But when it comes to fatherhood, Nick says there are lots of other factors that come into play. Confidence in paternity, for example—so if the female mates with multiple males that can make it harder to determine who the dad is. And that will affect whether the father helps out. In [ P.] campbelli hamsters, that's not much of an issue. In lab experiments, Katherine found that a female won't get pregnant if she mates with more than one male. Another potential factor favoring active dads is females preferentially mating with males who seem like they would be good at fatherhood. Here's Nick again. Royle: There's definitely kind of a selection for good quality parents effectively, and there's some evidence for that, particularly in birds, where biparental care is strongest, so you can get females kind of making choices of males based on their likely parental care. Feder: And so, even though active fatherhood is not the norm in most animals, there are actually lots of species where evolution favors it—[such as] seahorses, famously. Males carry their broods around in special pouches. They even have placentas in there! In some fish species, the male carries the fertilized eggs in his mouth, forgoing food, until they've hatched and grown and are ready to swim around independently. Even some beetles care for their young. Nick studies a species where males and females regurgitate meat for their little larvae kids. And of course, we have humans—fatherhood definitely varies from dad to dad and culturally, too. But there are a lot of devoted, caring human dads. There are dads who feed their kids, change their diapers, teach them how to drive, pay for college tuition—all activities I have no doubt [ P. ] campbelli dads would jump at the chance to do, given access to cars, currency and higher education. So if you happen to be in the arid semi-desert of Inner Mongolia one summer—summer being this hamster's breeding season—just know that you're in proximity to parental greatness. All around you in burrows just below ground are tiny hamster dads, working their fluffy butts off to operate birthing centers—they're delivering babies, keeping them warm, and just generally doing their very best to help their kids survive the harsh, dry land on which you walk. Feltman: That's all for today's Friday Fascination. We'll be back bright and early on Monday with our usual weekly news roundup. Science Quickly is produced by me, Rachel Feltman, along with Fonda Mwangi, Kelso Harper, Naeem Amarsy and Jeff DelViscio. This episode was reported and co-hosted by Elah Feder and edited by Jeff DelViscio. Shayna Posses, Emily Makowski and Aaron Shattuck fact-check our show. Our theme music was composed by Dominic Smith. Subscribe to Scientific American for more up-to-date and in-depth science news.

CERo Therapeutics Holdings, Inc. Announces Continued Enhancement of Intellectual Property Portfolio with Two Granted U.S. Patents and European Patent Application Allowance Regarding Company's...
CERo Therapeutics Holdings, Inc. Announces Continued Enhancement of Intellectual Property Portfolio with Two Granted U.S. Patents and European Patent Application Allowance Regarding Company's...

Business Insider

time11 hours ago

  • Business Insider

CERo Therapeutics Holdings, Inc. Announces Continued Enhancement of Intellectual Property Portfolio with Two Granted U.S. Patents and European Patent Application Allowance Regarding Company's...

Results in 18 Issued Patents and Allowed Patent Applications Internationally with Nine Total Patent Families SOUTH SAN FRANSCISCO, Calif., June 02, 2025 (GLOBE NEWSWIRE) -- CERo Therapeutics Holdings, Inc., (Nasdaq: CERO) ('CERo' or the 'Company') an innovative immunotherapy company seeking to advance the next generation of engineered T cell therapeutics that deploy phagocytic (i.e., target-cell eating) mechanisms alongside the array of built-in target cell destroying mechanisms used by T cells, announces two previously announced U.S. patent applications have been granted by the U.S. Patent and Trademark Office (USPTO), and one European patent application has been allowed by the European Patent Office, all of which significantly expand the Company's intellectual property portfolio. The USPTO granted U.S. Patent No. 12,291,557, titled, 'CHIMERIC TIM4 RECEPTORS AND USES THEREOF' on May 6, 2025. The granted claims cover certain design aspects of CER-1236, the Company's lead compound. This patent provides composition of matter protection for a chimeric TIM4 receptor comprising a TIM4 binding domain and canonical T cell signaling domains. Additionally, the European Patent Office has allowed European Patent Application No. 1882166.7 titled, 'CHIMERIC ENGULFMENT RECEPTOR MOLECULES AND METHODS OF USE' on May 16, 2025. The allowed claims encompass a chimeric engulfment receptor comprising a TIM4 binding domain and TLR2 signaling domain. The allowance of this European patent application expands protection of additional design aspects of CER-1236, which have already been granted in the U.S., Japan, and China. Finally, the USPTO granted U.S. Patent No. 12,303,551, titled, 'CELLULAR IMMUNOTHERAPY COMPOSITIONS AND USES THEREOF,' on May 20, 2025. This patent provides coverage for combination cellular immunotherapy compositions and methods of use for CER-1236. The patent covers combination of a chimeric engulfment receptor CD4 + T cell (CD4 + CER-T cell) with a chimeric antigen receptor CD8 + T cell (CD8 + CAR-T cell) or T cell receptor CD8 + T cell (CD8 + TCR-T cell), and their use to treat cancer. This type of combination therapy could be an exciting avenue to complement the CER-T cell technology with other powerful anti-cancer therapies. CERo's intellectual property portfolio now includes 9 total patent families with protection out to 2042 in the United States. With these additional granted patents and allowed application, CER-1236 and its platform technology is supported by 18 total issued patents and allowed patent application internationally. Chris Ehrlich, CERo Therapeutics CEO, commented, 'We continue to aggressively expand our intellectual property portfolio, as it ensures CERo's success in the market. These patents protect the core innovations of the CER-T technology that differentiate it from other cell therapies and demonstrate the true novelty of our design . We continue to seek a robust range of patents across multiple geographies that cover this technology in general, and CER-1236 in particular. The appreciation of the novelty of the CER-T technology by the patent offices validates the innovation and therapeutic potential of this approach, and we believe that we will continue to grow the portfolio. In the near term, we anticipate updates on our clinical trial progress in AML, and the announcement of initiating human trials to treat ovarian and non-small cell lung cancers.' About CERo Therapeutics Holdings, Inc. CERo is an innovative immunotherapy company advancing the development of next generation engineered T cell therapeutics for the treatment of cancer. Its proprietary approach to T cell engineering, which enables it to integrate certain desirable characteristics of both innate and adaptive immunity into a single therapeutic construct, is designed to engage the body's full immune repertoire to achieve optimized cancer therapy. This novel cellular immunotherapy platform is expected to redirect patient-derived T cells to eliminate tumors by building in engulfment pathways that employ phagocytic mechanisms to destroy cancer cells, creating what CERo refers to as Chimeric Engulfment Receptor T cells ('CER-T'). CERo believes the differentiated activity of CER-T cells will afford them greater therapeutic application than currently approved chimeric antigen receptor ('CAR-T') cell therapy, as the use of CER-T may potentially span both hematological malignancies and solid tumors. CERo has commenced clinical trials for its lead product candidate CER-1236 for hematological malignancies. This communication contains statements that are forward-looking and as such are not historical facts. This includes, without limitation, statements regarding the financial position, business strategy and the plans and objectives of management for future operations of CERo. These statements constitute projections, forecasts and forward-looking statements, and are not guarantees of performance. Such statements can be identified by the fact that they do not relate strictly to historical or current facts. When used in this communication, words such as 'anticipate,' 'believe,' 'continue,' 'could,' 'estimate,' 'expect,' 'intend,' 'may,' 'might,' 'plan,' 'possible,' 'potential,' 'predict,' 'project,' 'should,' 'strive,' 'would' and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. When CERo discusses its strategies or plans, it is making projections, forecasts or forward-looking statements. Such statements are based on the beliefs of, as well as assumptions made by and information currently available to, CERo's management. Actual results could differ from those implied by the forward-looking statements in this communication. Certain risks that could cause actual results to differ are set forth in CERo's filings with the Securities and Exchange Commission, including its most recent Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q, and the documents incorporated by reference therein. The risks described in CERo's filings with the Securities and Exchange Commission are not exhaustive. New risk factors emerge from time to time, and it is not possible to predict all such risk factors, nor can CERo assess the impact of all such risk factors on its business, or the extent to which any factor or combination of factors may cause actual results to differ materially from those contained in any forward-looking statements. Forward-looking statements are not guarantees of performance. You should not put undue reliance on these statements, which speak only as of the date hereof. All forward-looking statements made by CERo or persons acting on its behalf are expressly qualified in their entirety by the foregoing cautionary statements. CERo undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Scientists discover ‘dragon prince' dinosaur, the T. Rex's missing ancestor
Scientists discover ‘dragon prince' dinosaur, the T. Rex's missing ancestor

Yahoo

time18 hours ago

  • Yahoo

Scientists discover ‘dragon prince' dinosaur, the T. Rex's missing ancestor

Tyrannosaurus rex is a carnivorous icon. Exceeding 40 feet in length and nine tons, the bone-crushing giant stands out as the largest and last of its meat-eating family. Now a new and far smaller tyrannosaur is filling in the famous dinosaur's evolutionary backstory. The newest addition to the tyrannosaur family tree is named Khankhuuluu mongoliensis, which translates to 'dragon prince from Mongolia.' Described this week in the journal Nature, the dinosaur has been identified for the first time from two partial skeletons that include skull bones, vertebrae, part of the hips, and limb bones. Altogether, the pieces reveal a slender tyrannosaur that roamed Cretaceous Mongolia about 86 million years ago and was about 13 feet long—or about the size of juvenile T. rex that would stalk North America 20 million years later. In fact, Khankhuuluu even looked like a juvenile of later, larger tyrannosaurs, with round eye sockets, blade-like teeth, and long, shallow jaws better suited to biting fast rather than hard. (​T. rex had lips, upending its enduring pop culture image.) Khankhuuluu does more than simply add another dinosaur to the ever-growing roster of dinosaurs. 'Khankhuuluu gives us the origin story of tyrannosaurs,' says University of Calgary paleontologist and study co-author Darla Zelenitsky. In the early 1970s, Mongolian paleontologist Altangerel Perle found a pair of partial tyrannosaur skeletons in the eastern part of the country. The bones seemed similar to a small tyrannosaur that had been named before, Alectrosaurus. But when University of Calgary paleontologist and study co-author Jared Voris studied the bones during a research trip to Mongolia in 2023, he soon realized that the bones did not belong to Alectrosaurus at all. The bones from the two skeletons belonged to a new form of tyrannosaur that had been waiting to be discovered in collections for half a century. 'It had features like a hollow air chamber in side its nasal bone, which no other tyrannosaur species has,' Voris says. The fossils deserved a new name and have been recategorized as Khankhuuluu. Voris has found tyrannosaurs hiding in plain sight before. In 2020, Voris and colleagues named the 80 million-year-old tyrannosaur Thanatotheristes from bones assigned to another species found in Alberta. ("Reaper of Death" tyrannosaur discovered in Canada.) The finds are part of a burgeoning array of tyrannosaur discoveries. Instead of a simple line of evolution from early tyrannosaurs to T. rex, paleontologists have uncovered a wildly branching evolutionary bush of different tyrannosaur subgroups that came and went through the Cretaceous. The glut of new tyrannosaur species is allowing experts to piece together how big tyrannosaurs, including the gigantic T. rex, evolved and spread across vast stretches of the planet. When compared to other tyrannosaurs, the researchers found that Khankhuuluu is a close relative of the broader group of tyrannosaurs that include Gorgosaurus from Alberta, the bumpy-snouted Alioramus from Mongolia, and the iconic T. rex. The new family tree, as well as where the fossils were uncovered, create an updated picture of how tyrannosaurs evolved over 20 million years.'It is a pivotal species in understanding the evolutionary success of T. rex and its relatives,' says University College London paleontologist Cassius Morrison, who was not involved in the new study. In particular, the new analysis reveals how tyrannosaurs evolved into many different species as the carnivores wandered into new around the time of Khankhuuluu, Voris and colleagues propose, such small, slender tyrannosaurs were dispersing from prehistoric Asia into North America over a land bridge. 'Tyrannosaurs evolved into those giant apex predators and diversified very rapidly across North America,' Voris says, the first of what Zelenitsky calls 'two explosions of tyrannosaurs.' Some of the predators remained slender and chased smaller prey while others became bulkier and hunted larger dinosaurs, and they roamed habitats from southern California to New Jersey. (See how these fierce dinos evolved in our pages over 100 years.) The new study suggests, however, that the direct ancestors of T. rex, did not evolve in North America. Voris and colleagues propose that around 79 and 78 million years ago at least one lineage of tyrannosaurs ventured back into Asia. The researchers know this because of the close relationship of two tyrannosaur groups that at a glance might seem very different. When tyrannosaurs returned to Asia during this period and underwent their second explosion, one group was relatively slender and had long snouts decorated with small horns, like the 'Pinocchio' dinosaur Qianzhousaurus. The other group began to grow larger, with deep skulls adept at crushing bones, like Tarbosaurus. T. rex evolved from ancestors in the second group, a lineage of bone-crushers that once again crossed the land bridge back into North America between 73 and 67 million years ago—making T. rex a new form of predator that arrived from another continent. 'The new analysis provides strong support that the ancestors of T. rex evolved from a group of tyrannosaurs that ventured back to Asia after they had undergone an evolutionary radiation in North America,' Morrison says. Ultimately, the study suggests that the rise of one of Earth's largest carnivores was due to a back-and-forth between North America and Asia that took place over a period of 20 million years. Had a devastating asteroid impact not abruptly ended the Cretaceous 66 million years ago, tyrannosaurs would have undoubtedly kept changing.

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