
computer simulations
Science
Physics & Chemistry
Gravity Could Be Proof We're Living in a Computer Simulation, New Theory Suggests
Gravity may not be a fundamental force of nature, but a byproduct of the universe streamlining information like a cosmic computer.
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Washington Post
4 hours ago
- Washington Post
This is what a war on knowledge looks like
On the wall of Ulrich Mueller's neurobiology lab at Johns Hopkins University is a map with pins that show all the different countries where his research fellows were born. It's a visual representation of what makes American science so powerful — and why that primacy is threatened. 'The brightest minds from around the world are drawn to conduct research here,' Mueller proudly told an interviewer for a campus journal last month. The freedom and diversity of American higher education have operated like a magnet, attracting the world's most brilliant minds and spinning off trillions of dollars in wealth.


Gizmodo
8 hours ago
- Gizmodo
A Monkey Herpesvirus Could Hold Key to New Cancer Treatment
A cousin of herpes might just help us fight cancer. Scientists have engineered a protein derived from a herpesvirus in monkeys that could enhance the immune system's potency against cancer. Researchers at the University of Michigan detailed their work on the protein in a paper published last month. In experiments with mice, the protein prolonged the life of cancer-fighting T cells, leading to reduced tumor growth. The findings point to a novel way that we can further strengthen immune-related cancer treatments, the researchers say. The protein comes from herpesvirus saimiri, named after the squirrel monkeys (all members of the genus Saimiri) that the virus primarily infects. The researchers had identified the virus as carrying proteins that activate certain pathways in T cells—the immune system's frontline soldiers against infections and cancers—that extended their survivability. They ultimately engineered a modified version of one particular protein from the virus, called tyrosine kinase interacting protein (TIP). They hoped their version of TIP could bind to a protein in T cells that would stimulate the production of other proteins called STAT that could then boost the T cells' longevity and cancer-killing potential. As expected, the protein increased levels of STAT (specifically the protein STAT5) in T cells in a Petri dish. They then tested the protein on mice with melanoma and lymphoma. The T cells of treated mice lived longer and killed tumor cells more effectively, resulting in reduced cancer growth, the researchers found. 'Our findings demonstrate that signaling pathways can be rewired in T cells to sustain their function in solid tumors,' the researchers wrote in the paper, published in Science Immunology. In recent years, scientists have developed a class of treatments that ramp up the immune system's natural ability to recognize and attack cancers, which is broadly known as immunotherapy. So the U-M scientists believe that their protein could be used in combination with existing immunotherapies to keep T cells in tip-top cancer-bashing shape. More broadly, they believe that other organisms or their genes can be tweaked to modify our immune cells to make them better at fighting cancers. The team's protein is still experimental, so it will take plenty more research to know whether it can be safely and effectively used in people. But it may not take too long for other herpesviruses to contribute to cancer treatment. Several research teams have developed modified versions of the herpes simplex 1 virus (the primary cause of cold sores) to directly eradicate tumors. Some of these treatments have already begun to be tested in people, and have shown promise in early clinical trials so far.

Associated Press
10 hours ago
- Associated Press
Lockheed Martin's AI Fight Club™ Puts AI to the Test for National Security
Challengers across industry will face off in head-to-head battles simulating real-world scenarios Initiative creates a virtual environment, aligned to DOD standards, to test and develop the best AI systems for defense applications BETHESDA, Md., June 3, 2025 /PRNewswire/ -- Lockheed Martin [NYSE: LMT] is pioneering a competitive environment designed to accelerate the testing and operational deployment of artificial intelligence to support warfighters in their missions. Lockheed Martin's AI Fight Club™ is a comprehensive testing ground to simulate how AI systems perform in air, land, sea, and space domains. 'There has never been a more important time to prove which implementations of AI technologies are the best, to help the United States stay ahead of the threats facing our nation and allies,' said John Clark, Lockheed Martin's senior vice president of Technology and Strategic Innovation. 'AI Fight Club uses advanced simulation and visualization to evaluate AI in realistic and complex scenarios that mimic the challenges of modern warfare. Teams with the best AI will battle each other to determine the most robust, reliable and effective models.' A Proving Ground for the Best AI in the Nation AI Fight Club will use a synthetic environment developed by Lockheed Martin that simulates realistic scenarios across domains. This gives companies and teams of all sizes the opportunity to test their models in simulations that meet Department of Defense (DOD) qualifications. AI models will meet exacting DOD standards that are an integral part of the AI Fight Club proving ground, demonstrating the feasibility of the models for national security. Ultimately, events will bring together teams from across the industry and government experts to collaborate in a unique environment that fosters innovation, identifies vulnerabilities and informs the development of more advanced AI systems to benefit national security as a whole. How it works What's next? Lockheed Martin is actively developing the virtual arena that will host the first AI Fight Club. The company expects to complete the simulation environment by the end of Q3 2025, with the first AI Fight Club competition scheduled for Q4 2025. Lockheed Martin is announcing AI Fight Club now to give interested teams time to refine their AI and put their best foot forward and take on challengers. Teams interested in competing can visit or email [email protected] for more information. About Lockheed Martin Lockheed Martin is a global defense technology company driving innovation and advancing scientific discovery. Our all-domain mission solutions and 21st Century Security® vision accelerate the delivery of transformative technologies to ensure those we serve always stay ahead of ready. More information at View original content to download multimedia: SOURCE Lockheed Martin