10 Best Peptide Serums to Help Improve Your Skin in 2025
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While we can all agree ageing is a privilege, there are some mornings where we want our skin to look just that little bit more plump and bouncy.
Enter a peptide serum.
The latest craze in the beauty world by storm, peptides are short chains of amino acids that are commonly used to support the function of your skin barrier and increase overall hydration.
'Think of them as the building blocks of proteins like collagen and elastin, which are essential for firm, youthful-looking skin,' says Daniel Isaacs, Chief Product Officer at Medik8.
Even Hailey Bieber is a fan.
'I really, really love peptides for the skin, I think that it's one of the best ingredients to use', she told Glamour.
So much so, that she created the TikTok-viral Rhode Skin Peptide Glazing Fluid.
While we can't get our hands on it in Australia just yet, here are some more peptide serums you can use to help get Hailey's incredible skin – including one that delivers 'instant results' for plump and bouncy skin.
OUR TOP PICKS
Medik8 Liquid Peptides Advanced MP, $160 at Adore Beauty
Medik8 Liquid Peptides Advanced MP
$160 at Adore Beauty
Why we love it: Offers a clinically proven formula that feels lightweight and gentle on the skin.
What to consider: High price tag.
Tried and Tested by Stephanie Yip, eCommerce Travel Writer
As I boldly head into my 40s, wrinkles, fine lines and expression lines have begun to creep across my face at what feels like lightning speed. Yup, once you've seen them, it's hard to unsee them. So in an attempt to slow things down, I've upped my beauty routine to include Medik8's new Liquid Peptides Advanced MP.
Packed with Dual Mini Proteins, this pocket rocket aims to gently relax and smooth lines within minutes, and plump up skin by boosting its collagen, elastin and hyaluronic acid levels over a few weeks.
Obviously the sceptic in me took this with a grain of salt, but truly the effects were almost instantaneous and, after three weeks, my eye wrinkles have flattened out and my self confidence is through the roof.
On top of the results, I love how light and fast absorbing the serum is and that it's scent free, so it works well with the rest of my skincare routine.
I'm now actively using it to target a pesky frown line that's been bothering me for years and I'm confident that it'll be hardly noticeable in a few weeks.
Why we love it: The lightweight and silky formula feels great on the skin.
What to consider: High price tag for the little product you get.
Tried and Tested by Marina Tatas, Senior Shopping Writer
I've gone through a few bottles of this stuff and let me tell you, it is liquid gold. The Pro Collagen Multi Peptide Booster from Paula's Choice is one of the most hydrating, soothing and repairing serums I've ever tried. Formulated with a bunch of – you guessed it – peptides, this lightweight and silky serum works almost instantly and absorbs quickly. One thing I will say, I feel as if the dropper can be improved – the serum is almost a little too thick and can sometimes get stuck in the dropper but besides that, I am truly obsessed.
Why we love it: Olay's Super Serum offers five benefits in one.
What to consider: May feel too strong for super sensitive skin types.
Formulation: Serum | Size: 30ml | Best for: All skin types
What You Need To Know
If you're looking for a multipurpose peptide serum, Olay's Super Serum is the way to go.
It's packed with five potent ingredients that work hard while you sleep – peptides, niacinamide, glycerin, lactic acid and salicylic acid.
Expect to see a brighter and more hydrated complexion, as it helps to diminish signs of ageing and make sure your skin look more even and balanced.
With a lightweight and fast absorbing texture, this is the kind of serum you can use every night with no issue.
$34 at Amazon Australia
Why we love it: This a toner and serum hybrid that feels super lightweight on the skin.
What to consider: Some users did not see a massive difference from using this product.
Formulation: Essence | Size: 150ml | Best for: All skin types
What You Need To Know
The COSRX 6X Peptide Collagen Booster Toner Serum is our top pick when it comes to K-Beauty skincare. It's been named the 'best serum ever' by almost 5000 five-star reviewers on Amazon, with another happy shopper claiming it leaves their skin looking 'smooth and radiant'.
Due to its hybrid formulation, its recommended to use the COSRX toner serum as the first step of your skincare routine. Packed with six peptides, this will work hard to hydrate the skin and boost the rest of the products you choose to apply over the top.
It's also got niacinamide, adenosine, hyaluronic acid and allantoin to hydrate, even out your skin and overall improve the look of fine lines.
Why we love it: Budget-friendly price tag.
What to consider: Can sometimes be hard to get your hands on.
Formulation: Serum | Size: 52ml | Best for: All skin types
What You Need To Know
If you're shopping on a budget, the Advanced Clinicals Peptide Serum is a winner for under $20. Featuring loads of different peptides to hydrate the skin and make it appears softer and smoother.
It's also racked up over 10k five-star ratings on iHerb, with rave reviewers claiming this serum 'works wonders' for 'smooth and hydrated skin'.
$29.95 at Priceline
Why we love it: Low price tag and also great for sensitive skin.
What to consider: Some users claim the serum can pill when used with other products.
Formulation: Serum | Size: 30ml | Best for: All skin types
What You Need To Know
Another potent peptide serum for under $30 is this pick from BOOST LAB. Suitable for daily use and targeting visibly signs of ageing, the serum is formulated with pollustop, natural plant sugars and peptides.
It's also picked up great five-star ratings on the Adore Beauty website, with happy shoppers calling it a 'hidden gem' and commenting that they 'wake up with glowing and fresh skin'.
$99 at Adore Beauty
Why we love it: This is a multi-tasking serum that targets multiple signs of ageing.
What to consider: High price tag.
Formulation: Serum | Size: 30ml | Best for: Mature skin types
What You Need To Know
It's formulated with a firma-peptide complex, niacinamide, panthenol, kakadu plum extract and hyaluronic acid – all working together to harmoniously to make your skin feel more hydrated and look more plump and bouncy.
The ultra-lightweight texture easily absorbs into the skin, working well either morning or night.
$54.10 at The Ordinary
Why we love it: Great for those looking to target advanced signs of ageing.
What to consider: Some users report the serum bottle leaks on them.
What You Need To Know
This advanced serum from The Ordinary is formulated with 1 per cent copper peptides, and these help to support the skin's natural renewal process, as well as a bunch of antioxidants to boost the look of your skin.
The Ordinary Multi-Peptide + HA Serum, $52.60 at Myer
The Ordinary Multi-Peptide + HA Serum
$52.60 at Myer
Why we love it: Perfect for those looking for a peptide serum that can also address dry skin issues.
What to consider: Nothing we can fault.
Formulation: Serum | Size: 60ml | Best for: Dry skin types
What You Need To Know
This is the kind of peptide serum that can do a bit of everything. Not only do the five peptide technologies help to make your skin look more plump, but the addition of hyaluronic acid helps to give it that bounce.
It's been named a 'skincare essential' by five-star rating Myer shoppers.
Why we love it: An amazing hydrating serum for oily skin types.
What to consider: Some users felt it didn't make a big difference to their skin.
Formulation: Serum | Size: 30ml | Best for: Oily skin types
What You Need To Know
While you may not suspect this hydrating peptide-filled serum to be targeted towards oily skin types, it's the addition of one ingredient that really changes the game – niacinamide.
Not only does niacinamide boost skin barrier function, but it also helps to control oil and balance the skin. Pair that with hyaluronic acid and a blend of peptides, and you've got a universally hydrating serum – that's also priced at under $30.
It's even racked up an impressive average rating of 4.9 out of five on the Priceline website.
WHAT TO LOOK FOR WHEN BUYING A PEPTIDE SERUM
When choosing peptide serums to include in our list, we evaluated several factors:
Budget: You don't need to break the bank to find a potent peptide serum. We've got picks on our list for as little as $16.
Skin type: Your skin type can influence the kind of peptide serum you choose to buy. If you have oily skin, avoid anything filled with heavy oils. And if you have dry skin, looking for hydrating ingredients like hyaluronic acid and glycerin.
Added ingredients: While a peptide serum works great on its own, you can look for a serum with added ingredients to reap even more benefits.
HOW WE CHOOSE PRODUCTS
With hundreds of serums available, it's impossible to test every product out there. In our search for the best peptide serums, we read hundreds of customer reviews and looked at test results and ratings from product review sites to find the best one for you.
We also spoke to Daniel Isaacs, Chief Product Officer and Founding Partner of Medik8, to figure out why our skincare routine could benefit from adding a peptide serum.
FREQUENTLY ASKED QUESTIONS
DO PEPTIDE SERUMS ACTUALLY WORK?
Yes – like anything, if you use them consistently in your skincare routine, you'll see great results.
Daniel explains, 'peptides have always been a cornerstone of this approach due to their ability to deliver transformative results while working harmoniously with the skin. They are an essential ingredient for maintaining youthful, radiant skin.'
HOW LONG DOES IT TAKE TO SEE RESULTS FROM USING A PEPTIDE SERUM?
'Consistency is key with all skincare but some peptide products can help your skin start to show results with their key benefits within weeks, but long-lasting visible results will take 6-12 weeks,' Daniel shares.
WHAT MAKES MEDIK8'S LIQUID PEPTIDES ADVANCED MP DIFFERENT TO OTHER PEPTIDE SERUMS ON THE MARKET?
It all comes down to the formula, and that's why the Liquid Peptides Advanced MP is our top pick for peptide serums.
'Our breakthrough Dual MiniProteins are highly powerful like a peptide and potent like a protein. But the key is their shrunken size, which enables them to best penetrate the skin.'
He continues, 'think of them as small, but mighty in their ability to target cells that need them most to smooth and firm the skin for rapid wrinkle reduction.'
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While the tips of the star did lift a little, it wasn't really a bother unless you were looking closely. I even got a compliment from a fellow gym-goer who said: 'These look so fun - they take me straight back to Y2K.' The formulation includes amazing ingredients such as circa, tea tree oil, salicylic acid and niacinamide. My pimple was extracted cleanly without leaving an open wound, which is always a win. Overall, these glossy stars are a cute, effective and relatively inexpensive way to manage breakout days. Corsx Acne Patch, $5.98 (down from $7.90) at Amazon Why we love it: Barely noticeable Tried and tested by Jessica Smith, Body+Soul Health and Wellness Shopping Writer After seeing over 5000 five-star ratings on Amazon for the COSRX Acne Pimple Master Patch, I simply had to try the pimple patch for myself. Coming in three sizes, including a super small 7mm size, these are a great option if you need some healing dots that are small and targeted. Reviewers love how these are a little thicker and stay on the skin really well. I wore my COSRX pimple patch all day and was able to see how well the hydrocolloid gel absorbs excess fluid and helps flatten whiteheads. I also felt like the clear pimple patch was super discreet and barely noticeable on my chin throughout the day. Why we love it: 85,000 plus happy reviews Consider: Some users have noted that the patches are smaller than expected Amount included: 24 | Key Ingredient/s: Tea tree, calendula, rose seed oil and hydrocolloid What You Need To Know With over 85,000 reviews on Amazon, these K-beauty favourites are clearly doing something right. The Avarelle Spot Pimple Patches pack include 24 medium and large round patches, each infused with effective and gentle ingredients. Standout ingredients include calendula which is said to help sooth inflammation as well as rose seed oil which hydrates and promotes healing. 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Bought one box on launch, out of curiosity, and after trying them out, I immediately bought two more because there is no way I would want to run out of these babies!' BEST FUN PIMPLE PATCHES Skin Control Party Pack, $9 at Skin Control Why we love it: Variety of fun designs Amount included: 36 | Key Ingredient/s: Hydrocolloid, tea tree oil, and salicylic acid What You Need To Know The Skin Control Party Pack is perfect for adding a bit of sparkle to a bare face, makeup look or a sleepover skincare routine. Since launching in 2023 the Pimple Patch Party Pack has sold over 835,000 units and helped clear over 8.38 million pimples, so you know they are seriously good. It features adorable designs in the shape of stars, hearts, flowers, lips and rainbows. Beyond the fun factor, the formula still works hard with key ingredients such as tea tree oil and salicylic acid. Why we love it: Used by so many celebrities Consider: Pricey, and some colours may be hard to find in Australia Amount included: 32 | Key Ingredient/s: Hydrocolloid What You Need To Know These are the pimple patches that might of just kicked off the fun pimple patch trend. They've been on celebs like Hailey Bieber, Justin Bieber and Rosé from BLACKPINK. The patches come in a super cute compact container, with a built-in mirror and Starface's iconic smiley design. They come in a range of colours such as yellow, multi colour and even black. So there's a colour to match every aesthetic. But because they are so popular as well as being based in the US, they can be a bit harder to find in Australia and can cost as much as $70. They're made with 100 per cent hydrocolloid, which is designed to absorb fluid, reduce inflammation and help pimples heal faster. Here's what a happy reviewer had to say, 'Good quality item! Works on existing pimples and ones that are developing. They are barely noticeable when wearing and have a super cute design!' Another added, 'Very cute and compact! The case is very sturdy and the mirror on the inside is nice and clean! The star patches themselves are very cute and they stick on pretty well!' Hero Mighty Patch™ Surface – XL, $12.99 (down from $13.99) at Amazon Why we love it: Large patch for breakout areas Consider: Large patches can sometimes be very sticky. Amount included: 10 | Key Ingredient/s: Hydrocolloid What You Need To Know Once again the Mighty Patch goes viral on TikTok, with creator @Peyton showing a jaw-dropping overnight transformation using the XL patch. The XL patch is a total game changer for those with chaotic breakouts. The design is a large rectangular patch that covers wide zones, such as jawlines, noses, and chins. Made with 100 per cent hydrocolloid, it's the XL patch made for lazy skincare. Plus, you can alternatively purchase the Mighty Patch Nose for $13.39 at Amazon. It contains the same ingredients but it's just shaped to contour the nose. Rael Pimple Patches, Miracle Patches Large Spot Control Cover, $11.47 at Amazon Why we love it: Patch is a U-shape that easily morphs to the face Consider: Large patches are sometimes very sticky. Amount included: 10 | Key Ingredient/s: Hydrocolloid What You Need To Know With over 68,000 reviews on Amazon, the Rael Pimple Patches are seriously legit. The large U-shape is made to contour to the face easily. These are designed for acne hot spots and clusters, especially around the chin, nose and cheeks. While relatively expensive per patch, it comes out to be cheaper than say, applying five small patches in the same area. A happy reviewer writes, 'I had a light breakout on my jawline and decided to buy these. I applied to jawline, chin and nose which weren't even breaking out but I have large pores so I figured why not? 'Those patches were covered in gross white pus and sebum after. 'My skin feels so much better and cleaner and my pores look smaller after a few nights of wearing these! Definitely ordering more.' Another happy customer added, 'These patches have become a quick and easy go-to! I've forgotten these overnight and I have no issue, even with sensitive skin!' Peach Slices Deep Blemish Microdarts, $21.44 at Amazon Why we love it: Made for deep blemishes Consider: Expensive What You Need To Know With over 4000 reviews on Amazon, these might be the microdart pimple patches you need. These pimple patches contain 176 microdarts that self-dissolve deep into the skin targeting early-stage pimples or blemishes. They are great as overnight patches as they do come on the thicker side, but you can put them under makeup easily for daytime use. A five-star review wrote, 'These tiny dots are amazing. Nearly invisible on your skin and simple to apply.' Another happy customer agreed, writing: 'Fantastic to find a product that really does work well. Had a stubborn cyst-like spot under the skin, used this once and it pulled it all out to the surface in 24 hours.' Why we love it: Made for early stage pimples What You Need To Know Yes, another Rael Pimple Patches product included on this list and for good reason. These pimple patches are specifically designed to target early-stage pimples, delivering active ingredients that reach deep into the skin before a pimple fully forms. These feature microcrystal darts that dissolve over time once applied. A standout ingredient is succinic acid known for its gentle anti-inflammatory properties, helping clear blemishes without irritation. They also contain willow bark extract which works to unclog pores and is valued for its antibacterial and anti-acne benefits. One happy shopper wrote, 'Very effective, sucks all the gunk out and speeds healing. Would definitely buy again.' Another raving customer said, 'Wasn't sure about these but used them overnight and they work!' WHAT TO LOOK FOR WHEN BUYING PIMPLE PATCHES Ingredients Look for patches with active ingredients that match your skin's needs. Popular ingredients include hydrocolloid, tea tree oil, hyaluronic acid and salicylic acid. These are known for their effectiveness in minimising and reducing pimples. Patch size and shape Standard round and invisible patches are perfect for single and small pimples. If you are dealing with a cluster or larger area look for larger patches. Fun-shaped patches are also available, perfect for adding a pop of colour or playful touch to your skincare routine. Price Check the overall price of the pimple patch pack, as well as the cost per use to ensure it fits your skincare budget long term. Look for bulk packs or bundles for better value without compromising on quality. Skin sensitivity If you have sensitive or reactive skin, look for patches that are fragrance-free, hypo-allergenic or dermatologist tested. Stickiness and Wear Time A good patch should stick on well enough to stay in place overnight or throughout the day, but not so sticky that it tugs at your skin when removed. Check reviews to see how long they typically stay on especially if you plan to wear them during workouts or under makeup. HOW WE CHOOSE PRODUCTS With hundreds of products available, it's impossible to test every one out there. To help you find the pimple patches we tested a few well-known brands at different price points. In addition, our shopping team read hundreds of customer reviews and looked at test results and ratings from product review sites to find the pimple patches from premium to budget to help you find the right one for you. FREQUENTLY ASKED QUESTIONS DO PIMPLE PATCHES REALLY WORK? Yes – especially if you are dealing with surface level pimples like whiteheads. Most patches are made to draw out pus or fluid and protect the area from additional bacteria while it heals. WHEN SHOULD YOU APPLY A PIMPLE PATCH? Use them on clean and dry skin as soon as you notice a pimple forming. For whiteheads you can use a standard pimple patches, but for early stage pimples you can opt for microdart or microneedle patches before the breakout surfaces. CAN I WEAR PIMPLE PATCHES UNDER MAKEUP? Yes! Many brands make ultra-thin, clear patches designed specifically to be worn under makeup. Just make sure your skin is clean and dry when applying it. ARE THEY SAFE FOR SENSITIVE SKIN? Most pimple patches are made with gentle and non-irritating ingredients and are safe for sensitive skin. But it's always best to check the ingredients list and look for fragrance free or dermatologist tested products. We also recommendsigning up our newsletter – it's free and it means you'll get the best sales, shopping tips and guides delivered to your inbox every single week.
