Cubs at Cardinals Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 23
It's Monday, June 23 and the Cubs (46-31) are in St. Louis to take on the Cardinals (42-36). Ben Brown is slated to take the mound for Chicago against Matthew Liberatore for St. Louis.
The Cubs are 3.5 games ahead of the Milwaukee Brewers but are just .500 in their last 10 games. They recently dropped their series with the Mariners 2-1. They were outscored 30-20.
The Cardinals have been on a slight hot streak. They have won six of their last 10 games and back-to-back series.
Let's dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Cubs at Cardinals
Date: Monday, June 23, 2025
Time: 7:45PM EST
Site: Busch Stadium
City: St. Louis, MO
Network/Streaming: FanDuel Sports Network Midwest, Marquee Sports Network
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Cubs at the Cardinals
The latest odds as of Monday:
Moneyline: Cubs (-109), Cardinals (-110)
Spread: Cardinals 1.5
Total: 9.0 runs
Probable starting pitchers for Cubs at Cardinals
Pitching matchup for June 23, 2025: Ben Brown vs. Matthew Liberatore
Cubs: Ben Brown, (4-5, 5.57 ERA)
Last outing (Milwaukee Brewers, 6/17): 5.0 Innings Pitched, 2 Earned Runs Allowed, 6 Hits Allowed, 2 Walks, and 5 StrikeoutsCardinals: Matthew Liberatore, (4-6, 4.08 ERA)
Last outing (Chicago White Sox, 6/17): 6.0 Innings Pitched, 2 Earned Runs Allowed, 5 Hits Allowed, 0 Walks, and 4 Strikeouts
Cubs: Ben Brown, (4-5, 5.57 ERA)
Last outing (Milwaukee Brewers, 6/17): 5.0 Innings Pitched, 2 Earned Runs Allowed, 6 Hits Allowed, 2 Walks, and 5 Strikeouts
Cardinals: Matthew Liberatore, (4-6, 4.08 ERA)
Last outing (Chicago White Sox, 6/17): 6.0 Innings Pitched, 2 Earned Runs Allowed, 5 Hits Allowed, 0 Walks, and 4 Strikeouts
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Top betting trends & insights to know ahead of Cubs at Cardinals
The Cardinals have won 4 of their last 5 home games against NL Central teams
Each of the Cubs' last 3 games at the Cardinals have gone over the Total
The Cardinals have failed to cover the Run Line in 6 of their last 7 home games
If you're looking for more key trends and stats around the spread, moneyline, and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the Cubs and the Cardinals
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Our model calculates projections around each moneyline, spread, and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information, and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Monday's game between the Cubs and the Cardinals:
Moneyline: NBC Sports Bet is recommending a play on the St. Louis Cardinals on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago Cubs at +1.5.
Total: NBC Sports Bet is staying away from a play on the Game Total of 9.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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