
University of Plymouth research finds 20% of ocean now darker
More than a fifth of the global ocean has become darker over the past two decades, according to University of Plymouth research.The process, known as "ocean darkening", occurs when changes to the ocean's upper most level reduce the depth at which sunlight can travel.The study, published in Global Change Biology, found 21% of the global ocean had become darker between 2003 and 2022.Reasons for ocean darkening were believed to be down to factors such as changes in algal bloom dynamics, shifts in sea surface temperatures and artificial light, researchers said.
The study found more than 9% of the ocean - an area similar in size of Africa - had seen a reduction in light by more than 164ft (50m).A further 2.6% of the ocean saw a reduction of more than 328ft (100m), it said.
While the precise implications of the changes were not wholly clear, researchers said large numbers of the planet's marine species and ecosystem services could be affected.Dr Thomas Davies, associate professor of Marine Conservation at the university, said: "There has been research showing how the surface of the ocean has changed colour over the last 20 years, potentially as a result of changes in plankton communities."But our results provide evidence that such changes cause widespread darkening that reduces the amount of ocean available for animals that rely on the sun and the moon for their survival and reproduction."
'Fundamental changes'
Dr Davies said ocean darkening could have an impact on the air humans breathe, the fish they eat and the world's ability to fight climate change."Our findings represent genuine cause for concern," he said.Prof Tim Smyth, head of Science for Marine Biogeochemistry and Observations at the Plymouth Marine Laboratory, said some marine animals that need light could come closer to the surface as a result of the changes.This would cause increased competition for food and the other resources, he warned."That could bring about fundamental changes in the entire marine ecosystem," he said.
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Medical News Today
an hour ago
- Medical News Today
Longevity: Could a simple blood test tell all about your aging?
Researchers are developing a simple blood test that could assess your health span and lifespan. Image credit: Santi Nuñez/Stocksy. Intrinsic capacity is the sum of a person's mental and physical capacities, and is a measure of aging. Maintaining physical and mental function is a cornerstone of healthy aging. Formerly, assessing intrinsic capacity has been a costly and time-consuming process. Now, researchers have developed a method for assessing intrinsic capacity and age-related decline from a single drop of blood or saliva. They suggest that their test could be used to track aging and guide targeted interventions to maintain mental and physical function as people age. Intrinsic capacity (IC) is defined by the World Health Organization (WHO) as 'all the physical and mental capacities that a person can draw on and includes their ability to walk, think, see, hear and remember.' A person's intrinsic capacity is influenced by a number of factors, including the presence of diseases, injuries and age-related changes. Maintaining your intrinsic capacity is key to healthy aging. However, measuring intrinsic capacity has, until now, required sophisticated equipment and trained personnel. A new study has found that measuring DNA methylation in blood samples to assess intrinsic capacity effectively predicts all-cause mortality. The study, which is published in Nature Aging , suggests that the IC clock could be a useful tool for tracking aging and guiding targeted interventions to maintain function in older age. Thomas M. Holland, MD, MS, a physician-scientist and assistant professor at the RUSH Institute for Healthy Aging, RUSH University, College of Health Sciences, who was not involved in this study, commented for Medical News Today that: 'A blood- or saliva-based test for intrinsic capacity, known as DNAm IC, is a very promising tool in aging science. […] This test uses DNA methylation patterns, chemical tags that regulate gene activity, to estimate your IC biologically, offering insights into how well your body is functioning compared to your chronological age.' 'One of the most critical aspects is that this test can be done with a simple blood or saliva sample, making it accessible and noninvasive. It tells us not just how old you are, but how well you are aging, which is much more meaningful to help inform which interventions should be implemented, if any, to help prevent future health problems,' Holland explained. Elena Rolt, MSc, DipION, IFMCP, a Registered Nutritional Therapist and Functional Medicine Practitioner and cofounder of Health Miro, who was not involved in this research, also welcomed the findings. 'The DNA methylation-based intrinsic capacity (DNAm IC) test shows significant potential as a practical measure of biological aging,' Rolt told MNT . 'Unlike traditional epigenetic clock based tests, it also captures functional aging more directly.' 'As it reflects immune aging, physical capacity and lifestyle-related risk factors, this test may be particularly relevant for personalised aging interventions and preventive strategies,' she added. 'However,' Rolt cautioned, 'its use should be complementary to other markers — e.g. PhenoAge, GrimAge, functional tests — and its utility in clinical practice will depend on further validation.' Using data from 1,014 people from the INSPIRE-T cohort, aged between 20 and 102 years, the researchers developed an IC score using five aspects of age-related decline: cognition locomotion sensory (vision and hearing) psychological vitality. From blood and saliva tests, the researchers collected data on DNA methylation — a process that activates or deactivates genes. DNA methylation changes over time because of developmental mutations and environmental factors, and abnormal methylation patterns have been linked to several diseases. They used this, and the age-related decline data, to construct an epigenetic predictor of IC (an 'IC clock,' or DNAm IC), then evaluated associations between the IC clock and mortality. The researchers found that DNAm IC was strongly associated with overall health. People with the highest DNAm IC had better lung function, faster walking speed, greater bone mineral density and were more likely to view themselves as healthy. And people with a high DNAm IC lived, on average, 5.5 years longer than those with a low DNAm IC. Holland told us this was a very significant finding: 'Scientifically, this reflects strong associations between high IC and better immune function, lower chronic inflammation, and reduced risk for diseases like hypertension, heart failure, stroke, and other age-related conditions.' 'Simply,' he added, 'if your body is functioning well internally you are more likely to live longer and stay healthier. This test doesn't just give a snapshot of your current state; it may also offer a glimpse into your future health.' In everyone, intrinsic capacity declines with age, but there are measures that can help to slow that decline. This study found that people with a high dietary intake of oily fish, and sugar intake that was within recommended guidelines (no more than 5% of total energy intake), were more likely to have a high DNAm IC. Tunç Tiryaki, board-certified plastic surgeon and founder of the London Regenerative Institute, who was not involved in the recent study, explained the association: 'Oily fish are rich in long-chain omega-3 fatty acids (EPA and DHA), which have anti-inflammatory, neuroprotective and mitochondrial-supportive properties. These mechanisms are closely aligned with domains of IC such as vitality and cognitive function. Omega-3s also modulate gene expression related to immune responses and cellular senescence, pathways shown to be enriched in the DNAm IC signature.' 'Conversely, excessive sugar intake is known to accelerate glycation, oxidative stress, insulin resistance and chronic inflammation, all of which impair IC,' Tiryaki told MNT . 'Staying within recommended sugar limits likely supports metabolic flexibility and reduces inflammatory burden, preserving cognitive and physical function. These dietary factors likely influence DNAm IC by modulating epigenetic regulation and immune aging, thus helping maintain functional capacity,' he detailed. Holland, Tiryaki, and Rolt recommended a number of measures to help ensure healthy aging. These include: following a healthy diet, such as the MIND or Mediterranean diet, that is rich in fresh fruit and vegetables, wholegrains, and healthy fats, such as those found in nuts, olive oil and oily fish regular physical activity, including aerobic activity, strength training and balance exercises; Tiryaki emphasized that physical activity 'supports locomotion and vitality and influences mitochondrial function and immune health, both of which are linked to IC' cognitive and social engagement — keeping your brain stimulated and maintaining social networks are both associated with healthier aging. ensuring that you manage stress and any chronic diseases. Holland told us that the DNAm clock was a major advance in functional aging science: 'It links molecular biology with real-world outcomes like mobility, cognition and lifespan. While further validation is needed, especially in older adults with low IC, this study lays the groundwork for using personalised epigenetic markers to guide interventions in preventive geriatrics, longevity medicine and precision public health.' 'DNAm IC reflects not only how long you might live, but how well you might function, and that shift in focus is central to meaningful longevity.' – Thomas M. Holland, MD, MS Blood / Hematology Seniors / Aging


BBC News
an hour ago
- BBC News
Family move to Sierra Leone to volunteer on hospital ship
For the past year, marine pilot Ian Lawrence and his family of four have been volunteering on a hospital ship off the coast of Sierra was granted a year's unpaid leave from Associated British Ports in Southampton to work with the international healthcare charity Mercy Ships. Mr Lawrence's two children - eight-year-old Abigail and five-year-old Piran - went to school on the ship and his wife, Elizma, paused her business back family left Salisbury in July 2024, and Mr Lawrence captained the ship while medics carried out 1,600 surgeries. Mr Lawrence said: "I've spent 15 years at sea and became a ship's captain and then came ashore to work as a marine pilot. I met my wife on board a cruise ship so we're very much a maritime family. "So when we heard that Mercy Ships were looking for qualified mariners to volunteer on board their ships we signed up."The family have their own little cabin on the ship, and the two children attend the ship's academy, which teaches children from the age of four to 18. The Global Mercy is thought to be the world's largest purpose-built non-governmental hospital ship. At 174m (571ft) long and a gross tonnage of 37,000, the ship features six operating rooms, a hospital deck with 200 beds, a laboratory and various clinics including general outpatient, eye, and charity said the Global Mercy also had first-class training facilities for local medical professionals and is home to up to 600 volunteers who serve on the past year the medical team on the ship have undertaken more than 1,600 surgeries for 1,500 different patients. Mr Lawrence said: "In Sierra Leone there is a lot of facial tumours, cleft palates, bowed legs and also things such as burns, where the skin has contracted and caused the lack of mobility in someone's limbs." It is almost time to come home but has been an experience he and his family will never forget. "Sierra Leone is a wonderful country," he said. "The people are incredibly warm-hearted and welcoming.""Everywhere we've gone, we've been met with with smiles with greetings and welcomes."It's been an intense year, one where we've had highs and lows, but we really feel like we've lived and we have contributed, we've made a real difference to their part of the world and a population that really needed it."So it will be a year that will live with us for the rest of our lives, I'm sure." You can follow BBC Hampshire & Isle of Wight on Facebook, X, or Instagram.


Medical News Today
10 hours ago
- Medical News Today
Aging: Healthy habits could offset stroke, dementia, depression risk
New research finds certain diseases may be more common in people with a biomarker of aging but not in those with healthy lifestyles. Ivan Gener/Stocksy Age can increase a person's risk for several health conditions, including stroke, dementia, and late-life depression. A new study has identified an aging biomarker that is more common in people who develop stroke, dementia, and depression as they age. Researchers found that study participants who followed a healthy lifestyle appeared to offset the risks associated with this aging biomarker. 'Stroke and dementia are among the most prevalent age-related diseases, affecting millions worldwide and representing major health challenges for individuals, families, and healthcare systems,' Tamara N. Kimball, MD, a post-doctoral research fellow in the Brain Care Labs at Mass General Brigham told Medical News Today . 'With their impact expected to grow dramatically as populations age — and the number of people ages 60 and over projected to increase from 1 billion in 2020 to 1.4 billion by 2030 — developing effective prevention strategies has become urgent,' she said. Kimball is the lead author of a new study recently published in Neurology, the medical journal of the American Academy of Neurology, that has identified an aging biomarker that is more common in people who develop stroke, dementia, and depression as they age. However, researchers found that following a healthy lifestyle offsets the risk of the diseases associated with this aging biomarker. For this study, researchers analyzed medical records for more than 356,000 adults with a median age of 56 living in the U.K. 'Imagine your shoelaces have plastic tips that protect them from fraying — telomeres work similarly for your DNA,' Kimball explained. 'Every time your cells divide, which happens constantly as your body repairs and maintains itself, these protective tips get a little shorter. As they become shorter over time, their ability to protect DNA diminishes, leading to cellular aging and an increased susceptibility risk of age-related diseases.' 'The length of telomeres in white blood cells (leukocytes) can serve as a marker of biological aging and is influenced by genetic factors, lifestyle choices, and environmental stressors,' she added. At the study's conclusion, researchers found that study participants with the shortest telomere length had 5.82 cases per 1,000 person-years (number of people in the study and amount of time each person spent in the study) of the brain diseases dementia, stroke, and late-life depression, compared to 3.92 cases for participants with the longest telomeres. 'This shows people with the shortest telomeres presented (with) these brain diseases about 1.5 times more than those with the longest telomeres, demonstrating how biological aging affects brain health,' Kimball said. Scientists also discovered that study participants with short telomeres who had brain disease risk factors such as high blood pressure and smoking were 11% more likely to develop stroke, dementia, or depression than those with long telomeres. 'Our results demonstrate that individuals with low Brain Care Score — reflecting less favorable lifestyle factors like high blood pressure and smoking — consistently showed elevated risk for stroke, dementia, and depression when they also had shorter telomeres,' Kimball said. ' This suggests a compounded risk effect where biological aging and poor lifestyle choices increase disease susceptibility,' she said. Interestingly, Kimball and her team also found that participants with short telomeres, but who had high Brain Care Scores, did not have a higher risk of developing the studied brain diseases. 'In individuals with high Brain Care Score, the impact of leukocyte telomere length on disease risk was not significant,' Kimball explained. 'This may suggest that adopting healthier lifestyles and improving modifiable risk factors can mitigate the negative effects of having shorter telomeres.' 'Research shows that approximately 45% of dementia cases and up to 85% of strokes are linked to factors we can modify — like blood pressure, diet, and exercise,' she continued. 'Understanding the biological mechanisms by which lifestyle interventions influence cellular aging processes is essential for validating prevention strategies and developing more targeted, evidence-based interventions for brain health.' 'Our findings suggest that adopting healthier lifestyles and improving modifiable risk factors might mitigate some of the negative effects of shorter telomeres, which reflect adverse lifestyle choices in addition to social and environmental determinants of health earlier in life. In short, it is never too late to start taking better care of your brain.' — Tamara N. Kimball, MD MNT had the opportunity to speak with Clifford Segil, DO, an adult neurologist in private practice in Santa Monica, CA, who is also on staff at Providence St. John's Health Center in Santa Monica, CA, about this study. 'I am excited to see this research indicating a common cause of these three pathologies to develop into a possible treatment for telomere length protection or extension which could possibly decrease the occurrence of stroke, dementia, and depression in my elderly patients.' — Clifford Segil, DO Segil said that any time a common pathology is found between disparate neurological disease states, it is exciting as this research may stimulate a novel therapy. 'I often share with my patients that an ounce of prevention is worth a pound of treatment and studies like this support my desire to help my patients with common sense practical brain health preventative strategies,' he stated. For the next steps in this research, Segil said he would like to see this research group focus on specific lifestyle traits which cause patients to be able to maintain their 'large' telomere length and therefore decrease risk of stroke, dementia, and depression to figure out what to advise my patients to do for good brain health. 'I would then want them to do the reverse and figure out which habits or lifestyle choices specifically result in 'short' telomere lengths so I could advise my patients what to avoid in life,' he added. MNT also spoke with Jasdeep S. Hundal, PsyD, ABPP-CN, director of The Center for Memory & Healthy Aging at Hackensack Meridian Jersey Shore University Medical Center, and associate professor of psychiatry and neurology at Hackensack Meridian Health School of Medicine in New Jersey, about this research who commented that findings are not entirely surprising, but do add value. 'Short leukocyte telomere length has long been viewed as a general marker of biological aging and this study seems to support this association, especially for people with unhealthy lifestyles.' — Jasdeep S. Hundal, PsyD, ABPP-CN 'This reinforces what we see clinically in that modifiable risk factors remain central, even in the context of genetic or biological vulnerability, to brain health as we age even if the findings are correlational. It is interesting to speculate that short telomeres aren't necessarily causing these brain diseases, but they are a warning sign, especially in the setting of poor lifestyle choices,' Hundal explained. 'The burden of age-related brain diseases is rapidly rising, and we still have no cure for the most serious dementias like Alzheimer's disease,' he continued. 'Most of the risk factors for these diseases are modifiable, so there is real potential for prevention or risk reduction, even in people who may already be showing signs of biological aging.' Hundal said that studies like this highlight that maintaining a healthy lifestyle is not just 'good advice,' but can have genuine brain health consequences if someone is biologically vulnerable. 'We need more research identifying which interventions actually make a difference, for whom, and how to implement them in real-world settings,' he added. 'The focus should always be on translating findings like these into concrete strategies that help patients maintain brain health and independence for as long as possible.' Cholesterol Hypertension Stroke Alzheimer's / Dementia Seniors / Aging