White Sox at Astros Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 12
It's Thursday, June 12 and the White Sox (23-45) are in Houston to take on the Astros (37-30). Davis Martin is slated to take the mound for Chicago against Framber Valdez for Houston.
After a 4-2 loss in game one of the series, the Astros unloaded on the White Sox yesterday. Their 10-2 run was fueled by four RBI from Christian Walker. Walker went 3-4 with a home run.
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Let's dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch White Sox at Astros
Date: Thursday, June 12, 2025
Time: 8:10PM EST
Site: Minute Maid Park
City: Houston, TX
Network/Streaming: Space City Home Network, CHSN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the White Sox at the Astros
The latest odds as of Thursday:
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Moneyline: White Sox (+207), Astros (-256)
Spread: Astros -1.5
Total: 7.0 runs
Probable starting pitchers for White Sox at Astros
Pitching matchup for June 12, 2025: Davis Martin vs. Framber Valdez
White Sox: Davis Martin, (2-6, 3.62 ERA)
Last outing (Kansas City Royals, 6/6): 6.0 Innings Pitched, 2 Earned Runs Allowed, 5 Hits Allowed, 0 Walks, and 7 Strikeouts Astros: Framber Valdez, (6-4, 3.07 ERA)
Last outing (Pittsburgh Pirates, 6/5): 7.0 Innings Pitched, 2 Earned Runs Allowed, 4 Hits Allowed, 3 Walks, and 11 Strikeouts
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Top betting trends & insights to know ahead of White Sox at Astros
This season the Astros are 37-30 (.552) and 8-5 (.615) with Framber Valdez as the opener
The Astros' last 4 home games with Framber Valdez as the opener have gone under the Total
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the White Sox and the Astros
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursday's game between the White Sox and the Astros:
Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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