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Yahoo
26 minutes ago
- Yahoo
Editas Surpasses Therapeutic Gene Editing Threshold in New Preclinical Data
Editas Medicine, Inc. (NASDAQ:EDIT) ranks among the best CRISPR stocks to buy. At the European Hematology Association 2025 Congress on June 12, Editas Medicine, Inc. (NASDAQ:EDIT) revealed new in vivo data showing notable progress in gene editing for beta thalassemia and sickle cell disease. According to the study, a single dose of the company's proprietary targeted lipid nanoparticle (tLNP) in non-human primates exceeded the therapeutic threshold by achieving a mean on-target editing level of 58% in the HBG1/2 promoter region of hematopoietic stem cells. Editas' position in the gene editing market is strengthened by the result, enhancing the company's potential to offer a novel treatment for these illnesses with favorable biodistribution and minimal liver targeting. A clinical-stage biotechnology company, Editas Medicine, Inc. (NASDAQ:EDIT) develops gene-editing treatments that use CRISPR technology to modify patients' genomes to treat genetic diseases. Editas distinguishes itself from other major biotech companies that are seeking alternative genomic therapeutics by using an 'in vivo gene editing upregulation strategy.' While we acknowledge the potential of EDIT as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. Read More: and Disclosure: None.
Yahoo
41 minutes ago
- Yahoo
Mucus v. Phlegm: What's The Difference?
Most people are all too familiar with the icky, uncomfortable feeling of having mucus build up in the nasal passageways while suffering through a cold or bad allergy flare-up. Or is it phlegm, rather than mucus? What exactly is the difference between these two words? Do they describe the same slimy annoyance or separate substances? Below, experts break it down. 'Mucus is a slippery, gel-like substance your body naturally produces to keep your nose, throat, lungs and other parts of your respiratory system moist and protected,' Dr. Anitha Srinivasan, chief medical officer at NYC Health + Hospitals/Metropolitan, told HuffPost. 'It traps dust, germs and other particles so they don't irritate your airways or cause infection.' Your body constantly produces mucus as part of your everyday functioning immune system. 'It is kind of like saliva for the nose! Its main job is to keep those areas moist and to trap dirt, bacteria and viruses before they can cause harm,' said Dr. Nick Rowan, an endoscopic sinus and skull base surgeon with Johns Hopkins Medicine. 'One of my favorite ENT jokes is, 'you think it's mucus, but it's snot.'' It's a thin substance produced by mucous glands in mucous membranes throughout the body. 'Mucins are the key component that give mucus its characteristic viscosity and elasticity,' said Dr. Nora Tossounian, an internal medicine specialist with Hackensack University Medical Center. 'Mucus is mostly water, but also contains proteins, enzymes, antibodies and salts,' said Dr. Phillip Kadaj, an internal medicine specialist and medical expert with JustAnswer. 'Patients will often use mucus and phlegm interchangeably, but they are not quite the same thing.' 'Phlegm is a type of mucus, but specifically, it's the thicker mucus that's produced in your lungs and lower respiratory tract, especially when you're sick,' Srinivasan said. Regular mucus tends to be thin and slippery, and it is generally a constant presence on a day-to-day basis. Meanwhile, phlegm is thick and sticky and it appears when there's airway inflammation, hyperreactivity or an infection. 'It shows up when you are sick, such as with a cold, bronchitis or pneumonia,' Kadaj said. Allergies, sinus infection, asthma and other conditions can also lead to phlegm production. 'While all phlegm is mucus, not all mucus is phlegm,' Srinivasan noted. 'People often use these words interchangeably, but it's more accurate to think of phlegm as the thicker, usually colored mucus that you cough up during a cold or respiratory illness.' Tossounian compared the difference between phlegm and mucus to squares and rectangles. 'All squares are rectangles, but not all rectangles are squares,' she said. 'While technically phlegm is mucus, using 'mucus' to describe what's coughed up from the lungs isn't quite right. It would be like calling a square a rectangle — technically correct, but not precise.' As noted, mucus and phlegm are an important part of the body's defense system against pathogens and irritants. 'The extra mucus helps trap and flush out the germs causing the illness,' Srinivasan said. 'This can make your throat feel full or clogged, and you might notice more mucus or phlegm collecting there. Inflammation and irritation from the infection can also make mucus thicker and harder to clear, which adds to that clogged feeling.' If you're feeling uncomfortable, there are ways to clear out excess mucus and phlegm, which can help foster a quicker recovery. 'Especially when you're sick, staying well-hydrated is key ― water helps thin the mucus, making it easier to clear,' Rowan said. 'Saline nasal rinses, like with a neti pot or squeeze bottle, can flush mucus from the nose and sinuses and are something that I routinely recommend to patients, whether they have a cold or long-term sinus symptoms.' Warm fluids can also help loosen mucus, so drink herbal teas and try steam and warm showers. There are medication options as well, like antihistamines or nasal steroids, if allergies are the culprit. 'Be careful with over-the-counter decongestant nasal sprays like oxymetazoline,' Rowan warned. 'While they can offer quick relief, using them for more than a few days in a row can actually backfire. Your nose can become 'addicted,' leading to rebound congestion — a condition called rhinitis medicamentosa ― which makes the problem worse.' In general, you can boost your immune system with regular exercise, a healthy diet, proper hygiene and adequate sleep. 'If you ever notice mucus that's unusually thick or discolored ― like green or yellow ― or if it's paired with symptoms like fever, chest pain or shortness of breath, it's important to follow up with a healthcare provider,' Srinivasan said. 'And of course, keeping your hands clean and avoiding irritants like smoke can go a long way in keeping mucus production and your immune system at healthy levels.' Phlegm that is brown, pink, red or otherwise bloody in appearance could indicate bleeding in the respiratory tract that you'll want to investigate. Green or yellow mucus typically indicates that your body is fighting off an infection. Pay attention to color changes, especially if you notice excessive or persistent phlegm production. 'Cold and cough symptoms shouldn't be regular occurrences,' Srinivasan said. 'If they are, they may signal underlying issues such as environmental triggers, lung infections or a predisposition to respiratory problems. In some cases, frequent mucus or phlegm can be a sign of a certain congenital condition, like cystic fibrosis or primary ciliary dyskinesia. These scenarios should always be managed by a specialist.' Is It Better To Spit Out Or Swallow Your Mucus When You're Sick? If Your Boogers Look Like This, It's Time To See A Doctor Instead Of A Hot Or Cold Shower, Consider A Contrast Shower

Associated Press
an hour ago
- Associated Press
National Stuttering Association Brings Annual Conference to Denver
The largest annual gathering of people who stutter, families, and those who support them—bringing together 800 attendees for five days. DENVER, CO, UNITED STATES, July 3, 2025 / / -- The National Stuttering Association (NSA) is proud to present its 42nd Annual Conference, a transformative event designed to foster community for people who stutter. The event will take place from July 2 through July 6 at the Sheraton Denver Downtown (1550 Court Place in Denver). This one-of-a-kind event brings together approximately 800 people who stutter, speech-language professionals, families, and advocates for five days of connection, learning, and celebration. Attendees will engage in thought-provoking panel discussions and interactive workshops that center the lived experiences of people who stutter while deepening understanding of stuttering and approaches to support. Conference highlights include sessions on: --Parents: Embracing Stuttering and Fostering Acceptance --They Hear Our Voices: For Parents Who Stutter --HeardAI: Update --Teens: Just for Girls (Sisters Who Stutter) --Teens: Just for Guys --Passing Twice: LGBTQ+ People Who Stutter --Resiliency in the Workplace for People Who Stutter --Parents: Just for Dads --Stuttering in the Military: Q&A Session --Stuttering: Strength and Black Identity --Navigating Dating as a Person Who Stutters --How to Make Small Talk Your Superpower --Teens: Speak Up – Navigating Extracurriculars with a Stutter --Parents: Confidence, Communication, and Classroom Supports --Keynote Speaker: Mitch Guerra, SURVIVOR contestant and person who stutters The National Stuttering Association is a leading voice in destigmatizing stuttering and empowering people who stutter, serving thousands of people who stutter and their families annually. Stuttering is a speech disorder involving disruptions in a person's speech. Stuttering involves repetitions or prolongations of sounds and syllables or hesitations or blocks in making voiced sounds. As a nonprofit that supports people who stutter of all ages, we know that stuttering can be about more than speech and affect more aspects of everyday life than can be seen by someone outside the stuttering community. More information about the event, including the speaker lineup and schedule of events, is available at: Members of the media are welcome to attend the conference with advance arrangements. Interview subjects can be made available. Sarah Armstrong National Stuttering Association email us here Legal Disclaimer: EIN Presswire provides this news content 'as is' without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.