Capstan Therapeutics to Participate in Upcoming Scientific Conferences and Present New Preclinical Data in Support of Lead Anti-CD19 In Vivo CAR-T Candidate, CPTX2309
'Among the diverse set of presentations showcasing Capstan's non-viral CellSeeker™ platform, we are particularly encouraged by new preclinical data in support of our in vivo anti-CD19 CAR-T program, which demonstrate that a compact two-dose cycle was sufficient to induce rapid and deep B cell depletion in blood and tissues of non-human primates,' said Adrian Bot, M.D., Ph.D., Chief Scientific Officer and Executive Vice President of R&D at Capstan. 'These preclinical data highlight the potency of B cell depletion achievable with a transient in vivo CAR mRNA approach, without the need for lymphodepletion, and set the stage for clinical evaluation of CPTX2309.'
Featured Presentation:
American Society of Gene & Cell Therapy (ASGCT) 28 th Annual Meeting
Date:
Location: New Orleans, LA
Oral presentation title: A Two-Infusion Regimen with a Novel In Vivo Non-Viral Chimeric Antigen Receptor (CAR) Achieves up to 90% CD8+ T Cell Engineering and Tissue Depletion of Target Cells in Non-Human Primates (NHPs)
Presenter: Haig Aghajanian, Ph.D., Vice President of Research, Co-founder
Session title: CAR T Innovations in Autoimmune and Infectious Disease and Allergy
Date and time: May 15, 2025, 5:00 p.m. - 5:15 p.m. CT
Location: Room 393-396
Additional Presentations feature progress with our CellSeeker TM platform technology applicable to both mRNA and gene editing payloads:
Cellicon Valley '25: The Future of Cell and Gene Therapies
Date: Apr 30-May 2, 2025
Location: Philadelphia, PA
Oral Presentation Title: Leading the Charge for In Vivo Cell Therapy for The Treatment of Autoimmune Disorders
Presenter: Laura Shawver, Ph.D., Chief Executive Officer
Session title: Plenary Session 2, Leadership in Cell and Gene Therapies: The XX Factor
Date and Time: May 1, 2025, 10:20 a.m. - 10:30 a.m. ET
International Society of Cell & Gene Therapy (ISCT) 2025
Date: May 7-10, 2025
Location: New Orleans, LA
Poster title: Design and Preclinical Development of a Novel In Vivo Chimeric Antigen Receptor (CAR) Product for B-Cell Involved Diseases
Presenter: Haig Aghajanian, Ph.D., Vice President of Research, Co-founder
Poster number: 901
Session title: Poster Networking Reception 1; Immunotherapy (CAR-T, T Reg, NK Cells, etc.)
Date and time: May 7, 2025, 7:00 p.m. - 8.30 p.m. CT
21 st Annual PEGS Boston: The Essential Protein & Antibody Engineering Summit
Date: May 12-16, 2025
Location: Omni Boston Hotel at the Seaport, Boston, MA
Title: Chairperson's Remarks
Presenter: Adrian Bot, M.D., Ph.D., Chief Scientific Officer
Track: In Vivo CAR T Engineering: Moving into the Clinic
Date and time: May 15, 2025, 8:25 a.m. ET
Oral presentation title: In vivo mRNA-Based CAR T Cell Engineering for Treatment of B Cell Disorders
Presenter: John Rossi, Vice President, Translational Medicine
Track: In Vivo CAR T Engineering: Moving into the Clinic
Date and time: May 15, 2025, 9:00 a.m. ET
American Society of Gene & Cell Therapy (ASGCT) 28 th Annual Meeting
Date: May 13-17, 2025
Location: New Orleans, LA
Science Symposium: Targeted Nanosystems For Gene Transfer And Editing: Beyond Delivery To The Liver
Oral presentation title: In vivo immune cell engineering using targeted nanoparticles
Presenter: Priya Karmali, Ph.D., Chief Technology Officer
Date and time: May 16, 2025, 4:10 p.m. - 4:35 p.m. CT
Location: NOLA Theater B
Poster: Efficient In Vivo Gene Editing of T Cells Utilizing Novel Targeted Lipid Nanoparticles
Presenter: Esther Chen, Ph.D., Principal Scientist, R&D
Session title: Tuesday Poster Reception
Date and time: May 13, 2025, 6:00 p.m. - 7:30 p.m. CT
Location: Poster Hall I2
Poster: Effective Gene Editing in Hematopoietic Stem and Progenitor Cells (HSPCs) through a Novel Targeted Lipid Nanoparticle
Presenter: Esther Chen, Ph.D., Principal Scientist, R&D
Session title: Thursday Poster Reception
Date and time: May 15, 2025, 5:30 p.m. - 7:00 p.m. CT
Location: Poster Hall I2
TIDES USA
Date: May 19-22, 2025
Location: Manchester Grand Hyatt San Diego, San Diego, CA
Oral presentation title: In Vivo Engineering of Cells Using Targeted Lipid Nanoparticles
Presenter: Priya Karmali, Ph.D., Chief Technology Officer
Track: mRNA Technology and Applications
Date and time: May 21, 2025, 2:00 p.m. PT
About Capstan Therapeutics, Inc. (www.capstantx.com)
Capstan is a biotechnology company with a mission to multiply the therapeutic possibilities for patients by developing targeted in vivo RNA technologies. Our proprietary CellSeeker™ tLNP platform technology is composed of novel LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. tLNPs are designed to deliver payloads, including mRNA or gene editing tools, capable of reprogramming specific cell types in vivo. Capstan's CellSeeker™ technology has the potential to generate transformative therapies with possible applications across a broad range of disease areas, including autoimmune disorders, oncology, fibrosis, and monogenic blood disorders. For more information, please visit www.capstantx.com and follow us on LinkedIn.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Business Wire
22 minutes ago
- Business Wire
Edgewater Wireless CEO to join 'Catalysts of Innovation' Event in Silicon Valley
OTTAWA, Ontario & SAN JOSE, Calif.--(BUSINESS WIRE)--Edgewater Wireless Systems Inc. (TSXV: YFI) (OTC: KPIFF), the industry pioneer of Wi-Fi Spectrum Slicing™ technology, today announced that President & CEO Andrew Skafel will join the 'Catalysts of Innovation: Building Enduring Semiconductor Companies' panel hosted by Silicon Catalyst in collaboration with Arm Holdings Plc (NASDAQ: ARM) on , at TSMC, 2851 Junction Ave. #101, San Jose, CA. Join us in Silicon Valley — Sept 4 Our CEO will speak on Silicon Catalyst's Catalysts of Innovation panel—co-hosted with Arm. Hear how our AI-powered Spectrum Slicing™ and PrismIQ™ are redefining Wi-Fi QoS in performance-critical environments Share The event convenes startup leaders, investors, and ecosystem partners to explore what true product–market fit looks like in semiconductors—where capital efficiency, technical risk reduction, and early traction are paramount. The panel moderated by Laura Swan, General Partner, Silicon Catalyst Ventures, will feature Andrew Skafel (CEO, Edgewater Wireless), and the CEOs of Silicon Catalyst companies, Gigantor and Quadric. 'I am thrilled to be part of such an exciting panel discussion and look forward to meeting with the Silicon Valley crowd,' said Andrew Skafel, President & CEO of Edgewater Wireless. 'At Edgewater, we're redefining Wi-Fi from the silicon up. Our patented Spectrum Slicing approach and the PrismIQ™ product family are engineered to deliver unmatched Quality of Service in dense, performance-critical environments. I'm excited to share how we're aligning AI-driven innovation with clear go-to-market pathways—working with world-class partners across the ecosystem.' Details about the event can be found at: About Edgewater Wireless We make Wi-Fi. Better. Edgewater Wireless delivers unmatched Wi-Fi QoS—bar none—by intelligently mitigating congestion, managing spectrum allocation in real-time, and autonomously reconfiguring channel and link density—driving economic gains for service providers and their customers through reduced churn, improved efficiency, and high-performance connectivity in dense environments. Redefining Wi-Fi from the silicon up, Edgewater's patented, AI-powered Spectrum Slicing platform—delivered through the PrismIQ™ product family—breaks the limits of legacy Wi-Fi by enabling multiple concurrent channels in a single band. Wi-Fi Spectrum Slicing delivers 10x performance and up to 50% lower latency, even for legacy devices. With 26 patents and a fabless model, Edgewater is transforming the economics of Wi-Fi for service providers, OEMs, and enterprises—powering scalable, standards-aligned/leading connectivity across residential, enterprise, and Industrial IoT markets. A Silicon Catalyst portfolio company, Edgewater is building the intelligence wireless foundation for the next era of global connectivity. Visit Forward-Looking Statements This news release contains forward-looking statements and forward-looking information within the meaning of applicable securities laws. The use of any of the words "expect", "anticipate", "continue", "estimate", "objective", "ongoing", "may", "will", "project", "should", "believe", "plans", "intends" and similar expressions are intended to identify forward-looking information or statements. Although Edgewater Wireless believes that the expectations and assumptions on which such forward-looking statements and information are based are reasonable, undue reliance should not be placed on the forward-looking statements and information because Edgewater Wireless can give no assurance that they will prove to be correct. By its nature, such forward-looking information is subject to various risks and uncertainties, which could cause Edgewater Wireless' actual results and experience to differ materially from the anticipated results or expectations expressed. These risks and uncertainties, include, but are not limited to access to capital markets, market forces, competition from new and existing companies and regulatory conditions. Readers are cautioned not to place undue reliance on this forward-looking information, which is given as of the date it is expressed in this news release or otherwise, and to not use future-oriented information or financial outlooks for anything other than their intended purpose. Edgewater Wireless undertakes no obligation to update publicly or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required by law.
Yahoo
an hour ago
- Yahoo
SafelyYou Reveals New Platform to Revolutionize Care Delivery in Senior Living
New SafelyYou Halo™ solves for safety, wellness, and staffing issues building-wide, enabling operators to provide an unprecedented level of safety and residents to age in place longer This transformative innovation merges the core features of SafelyYou's proven AI solutions to deliver next-gen eCall, bringing unmatched speed, accuracy, and actionable insights to a previously outdated technology SAN FRANCISCO, August 21, 2025--(BUSINESS WIRE)--SafelyYou, the AI leader senior living relies on with a comprehensive platform for elevating care across the industry, has announced the release of a revolutionary new platform, SafelyYou Halo™, which uses world-leading AI to deliver next-gen eCall. This marks a significant leap forward in care delivery for senior living, as SafelyYou Halo™ works continuously to identify critical safety, wellness, and staffing patterns, so that interventions occur earlier, resources are optimized, and care planning is both more frequent and more effective. Critical challenges need a comprehensive solution. Senior living organizations are currently faced with a series of critical and complex challenges, and SafelyYou Halo™ offers a comprehensive, mobile-first solution, helping operators solve for outdated and ineffective technology, rising acuity, staffing to demand, and the need for building-wide safety. All of which means they can reduce risk and revolutionize how they operate. Once saddled with lagging technology that has failed to support the safety residents need, operators using this new platform now get SafelyYou's unequaled fall detection, as well as virtual check-ins and ambient care tracking, for an industry-first level of safety for residents across their buildings. Having to manage rising acuity across all care levels, operators with SafelyYou Halo™ will get rich wellness data so communities can update care plans sooner, have data-driven family conversations with greater insight into well-being, and deliver higher-quality care with improved outcomes for residents. Struggling with difficulty staffing to demand, operators can now accurately measure when, where, and who provides care in every room and common area, all without asking staff to wear lanyards or do any additional reporting. This lets operators clearly identify how long it takes to meet each care need, and then staff accordingly, bill appropriately, and confidently measure their staffing levels with precise data. SafelyYou Chief Product Officer Carlo Perez said, "We're incredibly excited to introduce SafelyYou Halo™. It's the complete reimagining of a technology that has been mandated for senior living, but never meaningfully updated. By bringing our world-leading AI to this foundational piece of care delivery, we're giving organizations the opportunity to redefine how care is managed and delivered building-wide, offering a never-before-seen level of accuracy and safety for an entirely new level of care quality and quality of life for residents." Built by the AI leader senior living relies on. SafelyYou has been dedicated to senior living since it was founded, and with almost ten years of experience with proven AI solutions tackling the toughest challenges in the industry, the company chose to build its own devices to help overhaul eCall. The SafelyYou Guardian™ custom sensors, pendants, and buttons that support this new platform reflect SafelyYou's deep understanding of senior living, operators' hurdles, and residents' needs. The result is refined, reliable hardware that delivers speed, accuracy, and actionable insights for organizations, while offering choice, convenience, and dependability for residents. George Netscher, SafelyYou founder and CEO, adds, "With SafelyYou Guardian™ hardware, we've created devices from the ground up to address critical care delivery needs in senior living communities, based on our years of experience dedicated to solving the toughest care challenges in the industry. In doing so, we're able to ensure that quality is unsurpassed at every step, every feature is informed by customer feedback, and care is transformed for seniors." About SafelyYou Originating in 2015 as the doctoral research of CEO George Netscher—and inspired by his own family's experience with Alzheimer's disease—SafelyYou was spun out of UC Berkeley's Artificial Intelligence Research Lab, one of the top five AI research groups in the world. The company's passionate mission is to empower safer, more person-centered care across senior living through world-leading AI, industry-changing hardware, and remote expert clinicians. SafelyYou is solving critical challenges in senior living, from resident falls and ER visits to staffing concerns, LOS, and NOI. All helping ensure that communities reach both their clinical and financial goals. SafelyYou is used by skilled nursing facilities and assisted living communities all across North America—from the largest national organizations to regional and local ones, too. SafelyYou is one of five most innovative fall technologies referenced in the Senate Falls Report (2019), a winner of the McKnight's Tech Partner of the Year, and has been named to Fortune's Impact 20 list. For more on SafelyYou, visit: Connect with SafelyYou on LinkedIn: View source version on Contacts For media inquiries, please contact:Chris Ryan, VP of Marketingcryan@ 224-343-7927
Business Wire
an hour ago
- Business Wire
SafelyYou Reveals New Platform to Revolutionize Care Delivery in Senior Living
SAN FRANCISCO--(BUSINESS WIRE)-- SafelyYou, the AI leader senior living relies on with a comprehensive platform for elevating care across the industry, has announced the release of a revolutionary new platform, SafelyYou Halo™, which uses world-leading AI to deliver next-gen eCall. This marks a significant leap forward in care delivery for senior living, as SafelyYou Halo™ works continuously to identify critical safety, wellness, and staffing patterns, so that interventions occur earlier, resources are optimized, and care planning is both more frequent and more effective. By bringing our world-leading AI to this foundational piece of care delivery, we're giving organizations the opportunity to redefine how care is managed and delivered building-wide Share Critical challenges need a comprehensive solution. Senior living organizations are currently faced with a series of critical and complex challenges, and SafelyYou Halo™ offers a comprehensive, mobile-first solution, helping operators solve for outdated and ineffective technology, rising acuity, staffing to demand, and the need for building-wide safety. All of which means they can reduce risk and revolutionize how they operate. Once saddled with lagging technology that has failed to support the safety residents need, operators using this new platform now get SafelyYou's unequaled fall detection, as well as virtual check-ins and ambient care tracking, for an industry-first level of safety for residents across their buildings. Having to manage rising acuity across all care levels, operators with SafelyYou Halo™ will get rich wellness data so communities can update care plans sooner, have data-driven family conversations with greater insight into well-being, and deliver higher-quality care with improved outcomes for residents. Struggling with difficulty staffing to demand, operators can now accurately measure when, where, and who provides care in every room and common area, all without asking staff to wear lanyards or do any additional reporting. This lets operators clearly identify how long it takes to meet each care need, and then staff accordingly, bill appropriately, and confidently measure their staffing levels with precise data. SafelyYou Chief Product Officer Carlo Perez said, 'We're incredibly excited to introduce SafelyYou Halo™. It's the complete reimagining of a technology that has been mandated for senior living, but never meaningfully updated. By bringing our world-leading AI to this foundational piece of care delivery, we're giving organizations the opportunity to redefine how care is managed and delivered building-wide, offering a never-before-seen level of accuracy and safety for an entirely new level of care quality and quality of life for residents.' Built by the AI leader senior living relies on. SafelyYou has been dedicated to senior living since it was founded, and with almost ten years of experience with proven AI solutions tackling the toughest challenges in the industry, the company chose to build its own devices to help overhaul eCall. The SafelyYou Guardian™ custom sensors, pendants, and buttons that support this new platform reflect SafelyYou's deep understanding of senior living, operators' hurdles, and residents' needs. The result is refined, reliable hardware that delivers speed, accuracy, and actionable insights for organizations, while offering choice, convenience, and dependability for residents. George Netscher, SafelyYou founder and CEO, adds, 'With SafelyYou Guardian™ hardware, we've created devices from the ground up to address critical care delivery needs in senior living communities, based on our years of experience dedicated to solving the toughest care challenges in the industry. In doing so, we're able to ensure that quality is unsurpassed at every step, every feature is informed by customer feedback, and care is transformed for seniors.' About SafelyYou Originating in 2015 as the doctoral research of CEO George Netscher—and inspired by his own family's experience with Alzheimer's disease—SafelyYou was spun out of UC Berkeley's Artificial Intelligence Research Lab, one of the top five AI research groups in the world. The company's passionate mission is to empower safer, more person-centered care across senior living through world-leading AI, industry-changing hardware, and remote expert clinicians. SafelyYou is solving critical challenges in senior living, from resident falls and ER visits to staffing concerns, LOS, and NOI. All helping ensure that communities reach both their clinical and financial goals. SafelyYou is used by skilled nursing facilities and assisted living communities all across North America—from the largest national organizations to regional and local ones, too. SafelyYou is one of five most innovative fall technologies referenced in the Senate Falls Report (2019), a winner of the McKnight's Tech Partner of the Year, and has been named to Fortune's Impact 20 list.
