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New ASCO AI Tool Promises Fast, Accurate Guidelines Access

New ASCO AI Tool Promises Fast, Accurate Guidelines Access

Medscape23-05-2025
The American Society of Clinical Oncology (ASCO) and Google Cloud have recently launched an artificial intelligence (AI)–powered search tool to provide accurate and fast access to ASCO's full library of evidence-based clinical guidelines, the society announced this week.
Developed with Google Cloud's Vertex AI platform and Gemini models, the ASCO Guideline Assistant will offer clinicians 'a more dynamic user experience, allowing them to ask follow-up questions for intuitive, easy integration of expert information into their patient care plans,' based on ASCO's published clinical practice guidelines, according to a society press release.
'This partnership unlocks the value of ASCO's trusted guidelines knowledge,' ASCO's chief executive officer, Clifford Hudis, MD, said in a statement. 'Google Cloud's AI expertise is the engine that will drive faster access to critical information, empowering oncology professionals to make rapid, evidence-based decisions for their patients.'
At ASCO's annual meeting next week, attendees will have a chance to explore the tool and learn more about 'Oncology and AI.'
Notably, the ASCO Guideline Assistant is designed to circumvent 'accuracy concerns often associated with publicly available AI tools,' according to ASCO.
While AI tools can help doctors make more informed decisions, save time, and optimize care, experts have also highlighted challenges and concerns with their use.
'Data-related concerns and human biases that seep into algorithms during development and post-deployment phases affect performance in real-world settings, limiting the utility and safety of AI technology in oncology clinics,' Medscape contributor Ravi B. Parikh, MD, and Likhitha Kolla wrote in a 2024 article in Cancer .
By providing access to timely, relevant information, the new tool can help alleviate the challenges oncologists face from rising cancer rates in younger Americans, a growing number of cancer survivors, rapidly expanding treatment options, greater fiscal constraints and a projected shortage of oncologists, ASCO noted.
'This is huge!' Sneha Singh, MD, posted on X in response to the announcement. 'Thank you @ASCO and @googlecloud for this guidelines agent!'
Another X user, Chiara Corti, MD, encouraged others to 'Try and play with it!'
'All the feedback will be welcomed by @ASCO and @googlecloud,' Corti added.
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'There's a core ethical dilemma': How ringside doctors in boxing and MMA approach a difficult job in brutal sports
'There's a core ethical dilemma': How ringside doctors in boxing and MMA approach a difficult job in brutal sports

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'There's a core ethical dilemma': How ringside doctors in boxing and MMA approach a difficult job in brutal sports

Margaret Goodman was a young neurologist just beginning to try out the role of ringside physician in her home state of Nevada when she got some advice from Donald 'Doc' Romeo, a man who by then estimated he'd worked somewhere in the neighborhood of 10,000 fights, from Muhammad Ali's destruction of Floyd Patterson to the 'eight minutes of fury' between Marvin Hagler and Thomas Hearns. 'First thing he told me was, 'don't go in the ring,'' Goodman said. 'I was like, what? I'm the ringside physician. If a fighter's hurt, that's what I'm here for. I've got to go in the ring. [Romeo] shook his head and said, 'no matter what happens, don't go in the ring.'' It took Goodman a while to understand what he was telling her. She didn't get it at first. But after she went from working amateur Golden Gloves events to major pro fights in Las Vegas, the epicenter of boxing in America, it started to become clear. Once a doctor steps in the ring, she's essentially on stage, in the spotlight, subject to all kinds of scrutiny. This is also why Goodman's partner, a fellow ringside physician named Edwin 'Flip' Homansky (the man called in to examine the bite marks on Evander Holyfield's ear that night against Mike Tyson in 1997), asked her if she was sure she'd be able to handle the pressure of this kind of work. 'I thought, pressure? I'm a neurologist. I deal with all kinds of really serious issues. But he was right,' Goodman said. 'Especially somewhere like Las Vegas, where everything is on TV, it is a lot of pressure. It's not just the crowds, either. It's a lot of other people expressing opinions on your work. Commentators, fighters, promoters, other ring doctors. Pressure from the [state athletic] commission. Pressure from the cornermen. You tell yourself none of that is important — and it isn't, because you're still going to do your job and do the right thing — but you realize there's a lot riding on your decisions.' For starters, there's the obvious. What if you recommended that the fight be allowed to continue, only for one fighter to suffer serious or even life-threatening injuries? What if you put a fighter in the ring who was medically unfit to be there in the first place? What if you failed to recognize the seriousness of a cut, and it ended up costing a fighter his eye? But what Goodman found, as she got deeper into the work and got to know more fighters and trainers on a personal level, was that she also had people's careers in her hands at times. And since she was one of the very few female doctors in this space, not to mention one with bright red hair, which made her instantly recognizable on TV broadcasts, people tended to remember every call she made — and they weren't hesitant about bringing them up to her later. 'If a fighter loses or gets stopped in a fight, it can really change what happens to them and where their careers go from there,' Goodman said. 'That's especially true in boxing, though also in MMA to some extent. There are implications, so you have to be aware of that. Bottom line, if someone's in danger, you get them out of there. But you do have to be aware of what that's going to mean for them.' Most fight fans never think about the doctors at ring or cageside unless something bad happens. Maybe the attending physician suggests a fight be stopped due to a cut that really isn't so bad. (Doctors have the power to stop fights on their own in some states, but in others can only recommend that the referee do so, which is a suggestion referees almost always follow.) Even worse, maybe the doctor fails to intervene on time, leaving a fighter to suffer serious injury or death long after the fight should have been stopped. It can be a tricky tightrope to walk for people who have dedicated so much of their lives to healing and helping people. In fight sports, they find themselves a party to something that has as its stated goal the inflicting of damage on one human being at the hands of another. 'This is the core ethical dilemma of every ringside doctor,' said Kirlos Haroun, an emergency room physician at Johns Hopkins Hospital in Baltimore, who also works as a ringside physician for the Maryland State Athletic Commission. 'Some doctors think about it a lot, and others don't. I've been challenged by some of my mentors who say, are you not consenting to long-term brain damage by being ringside? And I don't have a perfect answer to this. I think, without it being an excuse, this is something that society has accepted. We are allowing people to do this to make money. At a minimum, ringside doctors can be a pathway towards making it as healthy as possible.' As a longtime MMA fan, Haroun admitted that it's far less fun to watch fights as a ringside physician than as a regular observer. 'As a fan, I'm rooting for a knockout,' Haroun said. 'When I'm a ringside doctor, I'm praying for a decision because I do not want to walk in there.' But on those occasions when he is called upon to make a decision about which fights can continue, Haroun said, it requires a doctor to tap into a different kind of thinking. Because, quite frankly, none of this is good for the human body or brain. That's a given. But what a doctor is being asked to decide is whether it's suddenly become unreasonably dangerous as opposed to acceptably risky. That can be a strange head space for a physician to occupy. 'It's mitigation,' Haroun said. 'It's not removing risk, because you can't. The core idea here is to cause traumatic brain injury and knock the other person out. Personally, I think I'm usually able to disconnect it. But every once in a while I'm sitting next to a friend watching fights and they ask me, 'are you OK with this?' I do have these moments of ethical dilemma, and it's hard. It's hard.' Manjit Gosal is not only the medical director for the British Columbia Athletic Commission, he's also a family practice doctor and lifelong martial arts practitioner. This, he said, gives him a certain perspective on the work, since he knows what it feels like to push through pain in competition or insist he's fine when he knows he's not. He also knows what it feels like to suffer a concussion from a well-placed strike. 'I think it was one of my patients who first told me there were MMA events going down on one of the reserves here, back before it was legal,' Gosal said. 'So I thought, well I have to go help out and keep an eye on these guys. … I remember I got a call from the B.C. Athletic Commission — this is, again, way back before MMA was legal here — and they wanted to slap me on the wrist for it. I said, well, I'm a physician. I can help out any person who's in need, anywhere necessary. Then about a year and a half later, as MMA was getting legalized here, they called me back and said, 'we've heard you do these kinds of events. Would you like to work for us?'' Gosal said he's been present for every UFC event in Vancouver since the promotion first starting bringing shows to British Columbia in 2010. He's also worked multiple regional events over the years, watching the sport grow and change in the process. In that time he's had to stop fights over the protests of fighters and their corners. 'Initially, maybe they think they're fine to continue, they can push through this,' Gosal said. 'But I've never had a fighter afterwards say to me, 'how dare you stop that fight.' They've always acted respectfully and said, 'thanks for looking out for me, doc.' I tell them what I'm there to do is protect them, so they can still walk down the stairs and bring a fork to their mouth in their later years. And they understand that.' Many people think cuts come with the toughest judgment calls for a doctor, Gosal said, but it's generally not the case. Most facial lacerations produce more blood than genuine cause for concern. And those that are worth stopping a fight over tend to announce themselves with a certain obvious clarity. 'You're asking yourself, is it in a high-risk area? Is it blocking the vision?' Gosal said. 'If it is, that's pretty simple. It doesn't matter how big the fight is, if I can see bone and it's in an area where the next blow could damage the nerve, over the eye for example and affect this person's vision for the rest of his life, then the fight's got to stop.' The really tricky ones, in Gosal's experience, are the eye pokes that continue to plague MMA, with its open-fingered gloves. Those often come with controversy, as fans argue over what's inadvertent and what might be purposeful, as well as which fighters might be making it out to be more severe than it is in hopes of a point deduction or even a disqualification victory. A lot is left to interpretation in these instances. Sometimes a fighter's vision can clear quickly after an eye poke. Other times it might be impaired for hours or even days. The ringside doctor has a limited time in which to conduct an examination in the cage and make a decision. 'If it's accidental or whether it's deliberate, that doesn't really matter,' Gosal said. 'But there's two aspects to it. Can the athlete see or not? You can assess that, but it's a very short exam that you do when you're in there assessing somebody. You want to be very direct, very quick and get an answer. … But it's going to happen from time to time where those can be used for a way of getting out of a fight, which is fine too. If a fighter wants out, you want to stop it. But I'm sure the fighters sometimes make some calculations on that. Is it the first round? Is it the last round? Am I ahead? That's part of the game as well.' One thing Goodman learned from all her years working boxing and MMA events is that deception is always part of the fight game, and in many different ways. Fighters are constantly trying to trick each other, but also referees and doctors and maybe even their own coaches. That includes not just what happens in the ring or cage, but what's happened in the weeks or months before. 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We're Not Very Worried About Odysight.ai's (NASDAQ:ODYS) Cash Burn Rate
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We're Not Very Worried About Odysight.ai's (NASDAQ:ODYS) Cash Burn Rate

Explore Fair Values from the Community and select yours There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although made losses for many years after listing, if you had bought and held the shares since 1999, you would have made a fortune. But while the successes are well known, investors should not ignore the very many unprofitable companies that simply burn through all their cash and collapse. Given this risk, we thought we'd take a look at whether (NASDAQ:ODYS) shareholders should be worried about its cash burn. In this article, we define cash burn as its annual (negative) free cash flow, which is the amount of money a company spends each year to fund its growth. First, we'll determine its cash runway by comparing its cash burn with its cash reserves. Trump has pledged to "unleash" American oil and gas and these 15 US stocks have developments that are poised to benefit. When Might Run Out Of Money? A company's cash runway is the amount of time it would take to burn through its cash reserves at its current cash burn rate. As at March 2025, had cash of US$37m and no debt. In the last year, its cash burn was US$9.3m. Therefore, from March 2025 it had 4.0 years of cash runway. A runway of this length affords the company the time and space it needs to develop the business. Depicted below, you can see how its cash holdings have changed over time. Check out our latest analysis for How Well Is Growing? At first glance it's a bit worrying to see that actually boosted its cash burn by 4.4%, year on year. Given that its operating revenue increased 100% in that time, it seems the company has reason to think its expenditure is working well to drive growth. If revenue is maintained once spending on growth decreases, that could well pay off! We think it is growing rather well, upon reflection. Clearly, however, the crucial factor is whether the company will grow its business going forward. So you might want to take a peek at how much the company is expected to grow in the next few years. Can Raise More Cash Easily? We are certainly impressed with the progress has made over the last year, but it is also worth considering how costly it would be if it wanted to raise more cash to fund faster growth. Generally speaking, a listed business can raise new cash through issuing shares or taking on debt. Commonly, a business will sell new shares in itself to raise cash and drive growth. By looking at a company's cash burn relative to its market capitalisation, we gain insight on how much shareholders would be diluted if the company needed to raise enough cash to cover another year's cash burn. Since it has a market capitalisation of US$72m, US$9.3m in cash burn equates to about 13% of its market value. Given that situation, it's fair to say the company wouldn't have much trouble raising more cash for growth, but shareholders would be somewhat diluted. How Risky Is Cash Burn Situation? It may already be apparent to you that we're relatively comfortable with the way is burning through its cash. For example, we think its revenue growth suggests that the company is on a good path. While its increasing cash burn wasn't great, the other factors mentioned in this article more than make up for weakness on that measure. After taking into account the various metrics mentioned in this report, we're pretty comfortable with how the company is spending its cash, as it seems on track to meet its needs over the medium term. On another note, we conducted an in-depth investigation of the company, and identified 4 warning signs for (2 can't be ignored!) that you should be aware of before investing here. Of course, you might find a fantastic investment by looking elsewhere. So take a peek at this free list of interesting companies, and this list of stocks growth stocks (according to analyst forecasts) Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

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