Ozempic vulva: Experts clear the air on ‘rare side effect' causing vaginal dryness in women taking weight loss drugs
'While these medications can help shed significant weight, some women have reported a troubling and less-discussed side effect, now colloquially referred to as 'Ozempic vulva or Ozempic vagina',' said Dr Karuna Malhotra, aesthetic physician, Cosmetic Skin and Homeo Clinic in New Delhi's Rajouri Garden.
'Weight loss through GLP-1 therapy leads to a reduction of fat in multiple areas of the body, which may change physical contours, but there is no medical evidence to support that this causes pathological drooping of the labia. On the contrary, obesity is a well-known risk factor for urinary incontinence, and weight reduction, whether through lifestyle, surgery, or medications like semaglutide, has been consistently shown to improve bladder control,' said Dr Kovil.
Many of my patients report better mobility, confidence, and sexual satisfaction after weight loss, he said. 'As for dryness, there is no current evidence directly linking semaglutide to vaginal dryness. Hydration, hormonal status, and menopausal changes remain the primary factors influencing this,' said Dr Kovil.
Notably, Dr Malhotra said the vulva is composed of fatty tissue, and when this volume decreases rapidly, it may give a hollowed or aged appearance. For many women, this leads to a mismatch between their slimmer body and the way their intimate area looks, said Dr Malhotra.
According to Dr Shobha Gupta, medical director and gynaecologist, Mother's Lap IVF Centre, New Delhi and founder, Mumma's Blessing IVF and Birthing Paradise in Vrindavan, changes in the vulva may not just be cosmetic. 'Loss of fatty padding in the vulva can sometimes lead to discomfort, increased sensitivity, or even pain during physical activities and intimacy,' she said.
Dr Gupta emphasised that the vulvar tissues are hormonally sensitive, and significant weight changes can alter the balance of estrogen and fatty tissue support. This may sometimes result in dryness, irritation, or a higher risk of infections due to friction, said Dr Gupta.
*Speed matters: Rapid weight loss is more likely to cause skin laxity than gradual, sustainable weight loss, said Dr Gupta.
*Corrective treatments exist: Aesthetic options (fillers, PRP, radio frequency) and medical support (lubricants, hormonal balance if required) can help, said Dr Malhotra.
*Holistic care is important: Weight loss journeys should include skin care, hydration, and pelvic health awareness.
DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.
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