U of I researcher honored for his work in making crops more resilient
Stephen Long, the Ikenberry Endowed Chair Emeritus of Plant Biology and Crop Sciences at the U of I, was named a 2025 Top Agri-food Pioneer (TAP) by the World Food Prize Foundation. 39 innovators around the world were chosen, representing 27 countries. Each of the nominees worked to transform food systems, and work in fields related to food or agriculture.
U of I team creates global warming resilient potatoes
Long's research showed that by engineering crops to improve photosynthesis, it leads to better productivity. His work offered solutions to make crops more resilient in the face of climate change. He also led Realizing Increased Photosynthetic Efficiency (RIPE), an international research project, from 2012 to earlier in 2025.
'The world is running out of food relative to the number of people, and every year more people are starving according to the United Nations' definition,' Long told the College of Agricultural, Consumer & Environmental Sciences. 'Improving photosynthesis is one way to boost the food supply, and it has two main advantages. First, it will enable us to produce more per acre of land. Second, the process is fairly similar across crops. So if you can find a way of improving it in one, you can probably do it in all of them.'
Long said over time, his work has shown that making crops more resilient is possible.
Central Illinois family farms picking, selling corn until sold out
'I've been studying photosynthesis in crops for 50 years, and people used to believe that you can't improve it, or nature would have already done it,' he said. 'We've been able to show that is not the case; our crops probably only achieve about a third of the theoretical efficiency of photosynthesis. This suggests there's quite a lot of room for improvement, and now some of that improvement is being made.'
Long also said that after looking back, one of the things he is most proud of is the time he spent mentoring young researchers who are now carrying on the work.
The 2025 TAP trailblazers will be recognized at the Borlaug Dialogue in Des Moines, Iowa, in October.
Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
CNN
26 minutes ago
- CNN
3 myths about metabolism could be holding you back
EDITOR'S NOTE: The podcast Chasing Life With Dr. Sanjay Gupta explores the medical science behind some of life's mysteries big and small. You can listen to episodes here. (CNN)— Think speeding up your metabolism is key to losing weight? Metabolism has grown into one of the biggest buzzwords in the wellness industry — a tricky code that, if deciphered, is believed to unlock the secrets of weight loss and overall health. Despite the term's ubiquity, one scientist says many people don't understand much of how this basic bodily process works. 'They think it has something to do with how much food we can eat without gaining weight or something like that,' Dr. Kevin Hall told CNN Chief Medical Correspondent Dr. Sanjay Gupta recently on his podcast, Chasing Life. Hall wants to elevate metabolism for different reasons. 'Metabolism is just this incredible biochemical process that basically turns the food that we eat and the oxygen that we breathe into essentially … everything we are and everything we do,' he said. A leading nutrition and metabolism scientist, Hall is well-known for his research on contestants from the reality show 'The Biggest Loser' that helped explain what set participants who kept the weight off apart from those who gained it back. He spent more than two decades at the National Institutes of Health. His later work on ultraprocessed foods investigated its link to obesity, including one study that demonstrated it actively caused participants to overeat. Hall announced his early retirement and exit from NIH in April, citing censorship of how his research findings were communicated. He's now coauthor of the new book 'Food Intelligence: The Science of How Food Both Nourishes and Harms Us' alongside journalist Julia Belluz. Metabolism and weight loss enter conversations arm in arm, but this, according to Hall, can be reductive. 'I just find it incredibly frustrating sometimes that this idea of metabolism, this really beautiful physiological process that is so fundamental to life, is kind of talked about as, 'Oh well, if you take this supplement, you can boost your metabolism and lose weight,'' he explained to Gupta. You can listen to the full episode here. Is a faster or higher metabolism really the highway to weight loss? Hall is here to set the record straight, highlighting three misconceptions about metabolism that show there is more to it than meets the eye. One common belief is that a slower metabolism results in a higher body weight. But mostly, Hall said, the opposite is true. 'Generally, larger people have faster metabolisms than smaller people,' he told Gupta. Hall attributed the pervasiveness of this myth to the way researchers designed early metabolism studies. Scientists initially tried to match up participants' caloric intake to their weight, but they didn't account for the fact that these calorie counts were self-reported. It turned out that those with obesity often underreported the number of calories they ate to a larger degree than their leaner counterparts. This, Hall said, 'led people to a conclusion that, well, if they're eating less calories and they're maintaining their weight, then they must be burning less calories. And maybe the reason why they have obesity is because they have slow metabolisms.' Modern technology now allows researchers to rely on data, not participants' own reports. 'When we actually directly measure people's metabolisms, people with obesity have higher metabolic rates on average than people who are lean,' Hall noted. But the myth that we should be boosting metabolism to treat obesity has stubbornly persisted — and has at times led to deadly consequences. When Stanford University researchers discovered that the chemical compound 2,4-dinitrophenol, or DNP, increased metabolism levels in the 1930s, they enthusiastically promoted it as a safe and effective tool for treating obesity. While DNP did boost metabolism, it also led to side effects that included blindness and death, causing federal drug regulators to quickly withdraw it from the market. 'Maybe,' Hall suggested, 'it shouldn't be too much of a surprise later to realize that with something so fundamentally important to life as metabolism, you can't just turn it up and turn it down with a pharmaceutical drug and not expect some pretty severe side effects, including death.' Like weight, age might not affect metabolism as much as you may assume. 'It turns out that until you get to very advanced ages, we're talking 70s and 80s, it looks like our metabolic rate is roughly constant,' Hall said. There are, of course, changes in the aging body that can impact metabolic rates. People 'past the age of 30 or so,' Hall said, are 'tending to lose muscle mass or tending to lose lean mass, and they're tending to gain fat mass. And that alone is anticipated to result in a lower metabolism.' That's because lean muscle burns more calories than fat. But it's these age-related changes — that are not inevitable — and not age itself, that influence one's metabolism. 'Once you get rid of that effect … it doesn't seem like there's a fundamental aging effect to slow metabolism as, as we get older,' Hall concluded. A couple ways to combat the loss of lean muscle mass as you age is by engaging in twice-a-week strength training and getting enough protein in your diet (but no need to go overboard). Another pillar of metabolism mythology is the idea that a slow metabolism is the enemy of continued weight loss. Interventions such as dieting are believed to slow metabolism to the point that you can't lose any additional weight. But keeping your metabolism from slowing down isn't the key to sustained weight loss, Hall said. In fact, it's just the opposite. 'The people who are most successful at losing weight and keeping it off are the ones who sport the slowest metabolisms or the greatest reductions in metabolism,' he said. 'It's kind of like stretching a spring, right?' The more intensely someone diets or exercises, the more weight they'll lose and the more their metabolism will slow down, he explained in his book. Hall's research showed that a slower metabolism 'didn't seem to determine anyone's ability to lose weight or keep it off in the short or long run.' By uncoupling metabolism from the weight loss conversation, Hall said he hopes everyone can appreciate the phenomenon for what it really is. Misinformation about metabolism 'has really distracted people, I think, from the real beauty of what this is,' he told Gupta. 'It's harnessing the continuous flow of matter and energy in our food and in our breath and powering every cell in our body, as well as the bodies and cells of practically every organism that we have ever encountered,' Hall said. 'It's a fundamental component of life, and it's just incredibly fascinating.' We hope these three insights help you understand your metabolism better. Listen to the full episode here. And join us next week for a new episode of Chasing Life.
CNN
26 minutes ago
- CNN
3 myths about metabolism could be holding you back
EDITOR'S NOTE: The podcast Chasing Life With Dr. Sanjay Gupta explores the medical science behind some of life's mysteries big and small. You can listen to episodes here. (CNN)— Think speeding up your metabolism is key to losing weight? Metabolism has grown into one of the biggest buzzwords in the wellness industry — a tricky code that, if deciphered, is believed to unlock the secrets of weight loss and overall health. Despite the term's ubiquity, one scientist says many people don't understand much of how this basic bodily process works. 'They think it has something to do with how much food we can eat without gaining weight or something like that,' Dr. Kevin Hall told CNN Chief Medical Correspondent Dr. Sanjay Gupta recently on his podcast, Chasing Life. Hall wants to elevate metabolism for different reasons. 'Metabolism is just this incredible biochemical process that basically turns the food that we eat and the oxygen that we breathe into essentially … everything we are and everything we do,' he said. A leading nutrition and metabolism scientist, Hall is well-known for his research on contestants from the reality show 'The Biggest Loser' that helped explain what set participants who kept the weight off apart from those who gained it back. He spent more than two decades at the National Institutes of Health. His later work on ultraprocessed foods investigated its link to obesity, including one study that demonstrated it actively caused participants to overeat. Hall announced his early retirement and exit from NIH in April, citing censorship of how his research findings were communicated. He's now coauthor of the new book 'Food Intelligence: The Science of How Food Both Nourishes and Harms Us' alongside journalist Julia Belluz. Metabolism and weight loss enter conversations arm in arm, but this, according to Hall, can be reductive. 'I just find it incredibly frustrating sometimes that this idea of metabolism, this really beautiful physiological process that is so fundamental to life, is kind of talked about as, 'Oh well, if you take this supplement, you can boost your metabolism and lose weight,'' he explained to Gupta. You can listen to the full episode here. Is a faster or higher metabolism really the highway to weight loss? Hall is here to set the record straight, highlighting three misconceptions about metabolism that show there is more to it than meets the eye. One common belief is that a slower metabolism results in a higher body weight. But mostly, Hall said, the opposite is true. 'Generally, larger people have faster metabolisms than smaller people,' he told Gupta. Hall attributed the pervasiveness of this myth to the way researchers designed early metabolism studies. Scientists initially tried to match up participants' caloric intake to their weight, but they didn't account for the fact that these calorie counts were self-reported. It turned out that those with obesity often underreported the number of calories they ate to a larger degree than their leaner counterparts. This, Hall said, 'led people to a conclusion that, well, if they're eating less calories and they're maintaining their weight, then they must be burning less calories. And maybe the reason why they have obesity is because they have slow metabolisms.' Modern technology now allows researchers to rely on data, not participants' own reports. 'When we actually directly measure people's metabolisms, people with obesity have higher metabolic rates on average than people who are lean,' Hall noted. But the myth that we should be boosting metabolism to treat obesity has stubbornly persisted — and has at times led to deadly consequences. When Stanford University researchers discovered that the chemical compound 2,4-dinitrophenol, or DNP, increased metabolism levels in the 1930s, they enthusiastically promoted it as a safe and effective tool for treating obesity. While DNP did boost metabolism, it also led to side effects that included blindness and death, causing federal drug regulators to quickly withdraw it from the market. 'Maybe,' Hall suggested, 'it shouldn't be too much of a surprise later to realize that with something so fundamentally important to life as metabolism, you can't just turn it up and turn it down with a pharmaceutical drug and not expect some pretty severe side effects, including death.' Like weight, age might not affect metabolism as much as you may assume. 'It turns out that until you get to very advanced ages, we're talking 70s and 80s, it looks like our metabolic rate is roughly constant,' Hall said. There are, of course, changes in the aging body that can impact metabolic rates. People 'past the age of 30 or so,' Hall said, are 'tending to lose muscle mass or tending to lose lean mass, and they're tending to gain fat mass. And that alone is anticipated to result in a lower metabolism.' That's because lean muscle burns more calories than fat. But it's these age-related changes — that are not inevitable — and not age itself, that influence one's metabolism. 'Once you get rid of that effect … it doesn't seem like there's a fundamental aging effect to slow metabolism as, as we get older,' Hall concluded. A couple ways to combat the loss of lean muscle mass as you age is by engaging in twice-a-week strength training and getting enough protein in your diet (but no need to go overboard). Another pillar of metabolism mythology is the idea that a slow metabolism is the enemy of continued weight loss. Interventions such as dieting are believed to slow metabolism to the point that you can't lose any additional weight. But keeping your metabolism from slowing down isn't the key to sustained weight loss, Hall said. In fact, it's just the opposite. 'The people who are most successful at losing weight and keeping it off are the ones who sport the slowest metabolisms or the greatest reductions in metabolism,' he said. 'It's kind of like stretching a spring, right?' The more intensely someone diets or exercises, the more weight they'll lose and the more their metabolism will slow down, he explained in his book. Hall's research showed that a slower metabolism 'didn't seem to determine anyone's ability to lose weight or keep it off in the short or long run.' By uncoupling metabolism from the weight loss conversation, Hall said he hopes everyone can appreciate the phenomenon for what it really is. Misinformation about metabolism 'has really distracted people, I think, from the real beauty of what this is,' he told Gupta. 'It's harnessing the continuous flow of matter and energy in our food and in our breath and powering every cell in our body, as well as the bodies and cells of practically every organism that we have ever encountered,' Hall said. 'It's a fundamental component of life, and it's just incredibly fascinating.' We hope these three insights help you understand your metabolism better. Listen to the full episode here. And join us next week for a new episode of Chasing Life.
Yahoo
an hour ago
- Yahoo
Chai Discovery Announces $70 million Series A To Transform Molecular Design
Fundraise follows foundation model breakthrough in fully de novo antibody design with the Chai-2 series of models Menlo Ventures-led round takes total funding to $100M Former Pfizer Chief Scientific Officer Mikael Dolsten, M.D., PhD., joins board SAN FRANCISCO, August 06, 2025--(BUSINESS WIRE)--Chai Discovery, the AI company that predicts and reprograms the interactions between biochemical molecules to accelerate life-changing therapeutics, today announced its $70 million Series A financing round. The fundraise was led by Menlo Ventures, including investment from their Anthology Fund, a joint partnership with Anthropic to identify and back promising AI companies, with participation from new investors Yosemite, DST Global Partners, SV Angel, Avenir, DCVC, and others. It also included existing investors Thrive Capital, OpenAI, Dimension, Neo, Lachy Groom, and Fred Ehrsam, among others. "Progress towards game-changing drugs and treatments is far too slow, stymied by costly trial-and-error experiments," said Joshua Meier, CEO and co-founder. "Chai Discovery exists to push the boundaries of what's possible in this field, applying frontier AI to transform biology from science to engineering, so that breakthroughs can be designed rather than simply discovered." Chai was founded in 2024 by Joshua Meier (ex AI drug discovery firm Absci; Facebook AI; OpenAI), Jack Dent (ex Eng and Product leader at Stripe), and AI researchers Matthew McPartlon and Jacques Boitreaud. Mikael Dolsten M.D., PhD., the former Pfizer Chief Scientific Officer responsible for advancing 150 molecules into clinical trials and delivering 36 approved medicines, is joining the company's board of directors. "I'm proud to join Chai Discovery and redefine biology from science into engineering," Dr. Dolsten said. "This is going to be an incredible journey with an incredible team." Last year, the company closed a $30 million seed round led by Thrive Capital, OpenAI, and Dimension. Soon after, they released Chai-1, an open-source foundation model for molecular structure prediction that performs at the state-of-the-art Last month, the team unveiled a further leap in AI-driven drug discovery with their Chai‑2 breakthrough, delivering fully de novo antibody design with a near-20% hit rate. By contrast, traditional lab based methods often have to screen millions to billions of antibodies to find hits, and the previous state of the art for computational methods was only 0.1%. When inputting only the target antigen and epitope, Chai‑2 can generate successful binders from scratch against a wide variety of targets. This means that scientists working on a target antigen, a specific disease-causing protein such as a virus or type of cancer, can use Chai-2 to design, from scratch, completely new antibodies that can hit the right spot. "Before Chai-2, the process was not unlike searching a giant bunch of keys for the right fit for a lock—but there are millions of keys," said Matthew McPartlon, co-founder. "Now, it's like having a master locksmith design exactly the right shape key, based only on your description of the lock. A company had spent more than three years and over $5m on a problem. With Chai-2, we were able to find an experimentally validated solution within two weeks." The funding will be used to further develop the Chai platform, applying it toward previously inaccessible targets, and onboarding select partners. "Chai is an exceptional technical team building foundation models for biology to transform drug discovery," said Greg Yap, Partner at Menlo Ventures. "Chai-2 demonstrates amazing progress in antibody design, and we have seen a meaningful fraction of the biotech industry already apply for Chai-2 access. At Menlo, we invest deeply in both AI foundation models and technology-enabled biology–we believe Chai can help create better medicines faster." For more information on Chai Discovery and its platform, visit About Chai Discovery Chai Discovery builds frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules, the fundamental building blocks of life. Its mission is to transform biology from science into engineering. The team hails from pioneering research and applied AI companies such as OpenAI, Meta FAIR, Stripe, and Google X, and is backed by top investors including OpenAI, Thrive Capital, Menlo Ventures and Dimension. View source version on Contacts press@ Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
