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Unexpected medical issue grounds Isle Royale wolf-moose survey

Unexpected medical issue grounds Isle Royale wolf-moose survey

A last-minute medical issue grounded researchers' annual wolf-moose survey on Isle Royale this past winter, marking yet another year that scientists have run into problems trying to count the animals on the remote island park.
Isle Royale is a 134,000-acre (54,200-hectare) island in far western Lake Superior between Grand Marais, Minnesota, and Thunder Bay, Canada. The island, which doubles as a national park, offers scientists a rare chance to observe wolves and moose in their natural habitat, free from human influence. Researchers have conducted an annual survey of the island's wolf and moose population since 1958.
Scientists from Michigan Tech University had planned to return to the island in January to conduct seven weeks of aerial surveys by ski-planes. Snow and bare branches make tracking easier from the air in winter, but the island lacks a land-based runway, forcing the scientists to use ski-planes that can land in the island's ice-covered harbors.
The scientists released their annual report on Tuesday, but it does not include any new population estimates. The report notes that the researchers were not able to get into the air at all this winter because 'our usual aviation resources became unexpectedly unavailable due to extenuating circumstances and there was insufficient time to find a suitable alternative.'
Michigan Tech spokesperson Hailey Hart explained in a telephone interview that the ski-plane pilot developed a last-minute medical issue and couldn't fly. The scientists were unable to find a replacement pilot.
'It was very sudden,' Hart said. 'It was a big bummer for them.'
Researchers have experienced disruptions in three of the last five years they've attempted the survey. The COVID-19 pandemic forced them to cancel the survey in 2021, marking the first time since 1958 that population counts weren't conducted.
They had to cut the survey short in February 2024 after weeks of unusually warm weather left the ice surrounding the island unsafe for ski-plane landings. The National Park Service suspended the researchers' work and ordered them to evacuate.
Data the scientists gathered before they left showed the wolf population stood at 30 animals, down from 31 the previous year. The moose population stood at 840, down 14% from 2023.
Most of Tuesday's report discusses observations a group of college students made on the island in the summer of 2024. They noted regular wolf sightings, observed a wolf chasing a moose and found the bones of a wolf that died a decade ago, well before the park service began relocating wolves to the island in 2018. The students also found the remains of 115 moose, including 22 believed to have died in 2024. Researchers believe wolves killed all but three of those moose.
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The Pandemic Literally Aged Our Brains
The Pandemic Literally Aged Our Brains

Medscape

time5 hours ago

  • Medscape

The Pandemic Literally Aged Our Brains

This transcript has been edited for clarity. Welcome to Impact Factor , your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson from the Yale School of Medicine. Living through the COVID pandemic aged your brain by about five and a half extra months. This, according to new research. It's a pretty scary headline, but what does 'brain age' even mean, how do you measure it, and what risks does a five-and-a-half month older brain have to face? We're going to use what's left of our brains to dig through the data this week. Stay tuned. The study generating those scary headlines is 'Accelerated Brain Ageing During the COVID-19 Pandemic', from Ali-Reza Mohammadi-Nejad and colleagues, appearing in Nature Communications . But before we get into it, a reminder that SARS-CoV-2, the virus that caused the COVID-19 pandemic, is a weird one, especially when it comes to the brain. It was pretty early in the pandemic when we realized that one of the rather unique symptoms that came with COVID infection, differentiating it from the common cold and flu infections and the like, was anosmia — the loss of smell. It turned out this was due to infection of some epithelial cells in the nose, with inflammation impacting the olfactory bulb of the brain. To be clear, evidence of direct brain infection by SARS-CoV-2 is fairly weak. Neurons don't express high levels of the ACE2 receptor — the viruses' point of entry to other cells. And while some autopsy studies have found viral genetic material in the brain, it has been quite difficult to find live virus in brain cells. But secondary effects of the virus — inflammation and microclotting— do affect the brain. And multiplestudies have suggested that infection can worsen certain cognitive outcomes. There was more to the pandemic than just the virus, though. There was social isolation, higher levels of stress, and loss of work and other cognitively stimulating activities. In other words, there were lots of reasons for people's brains to get a little worse during those few years. That's really what the Nature Communications study is looking at. It's an overall sense of how our brains are doing, and 'brain age' is a useful proxy for that concept. So, what is brain age? It's pretty straightforward. Imagine a carnival barker doing the 'guess your age' thing. You come up, they take a look at you, squint, and call out a number, usually with startling accuracy. The carnival barker is using various clues — features on your face, wrinkles, hairstyle, and so on — to make a guess. We can do the same thing with an MRI machine. We just have to teach a computer what the brains of different ages look like. That's what researchers did here. Using the huge UK biobank cohort, they took brain scans of more than 15,000 healthy people of various ages and trained a machine-learning model to predict age based just on the images. It got pretty accurate, as you can see here. Of course, it's not perfect. Nor would we expect it to be. Some people's brains look younger than their stated age. Call it the Paul Rudd effect. And, of course, some brains look older than they should. The distance between your calendar age and your brain age is the 'brain age gap' (BAG), with higher numbers implying that your brain is older than it should be. This gap seems to stay pretty consistent over time. If your BAG is 5 years right now, it tends to stay around 5 years even a few years later, provided nothing intervenes to more rapidly age your brain. If anyone ever accuses you of having an excessive BAG, you can say 'that's not my bag, baby.' (And that ends the '90s references for this week.) It's the repeated brain scans that make this study interesting. The researchers identified about 1000 participants who had multiple brain scans, on average about 2 years apart. For 432 of those folks, the pandemic happened between the two scans. So, we can look at how much their brains aged in that timeframe and compare that aging to a group who was not exposed to the pandemic. This is the meat of the study. Here are the primary results. Remember, BAG is supposed to stay pretty stable if nothing else has changed. And that's what we see in the control group. Between the two scans, there was, on average, no change in BAG — though the distribution here encompasses changes in both directions. Now we add the pandemic group. What you see is that the distribution has shifted, on average by 5.5 months. That's where we get that headline that started this whole thing. But of course, 5.5 is just the average change in BAG. Different people's brains aged at different speeds. Still, overall, this is a statistically significant difference. You're probably wondering why some brains aged more than others. The 5.5 month result is the effect of the pandemic – not necessarily infection. Out of the 432 individuals with a postpandemic scan, 134 actually had documented COVID-19 before that second scan. Interestingly, the increase in brain age was similar among those infected and those not infected. To be fair, only five of those infected were sick enough to be hospitalized, but it still seems that the bulk of the aging effect of the pandemic may have been due to factors independent of the virus itself; factors that made the pandemic effect worse. The brains of older people and men seemed to age more during the pandemic than those of younger people and women. Poor socioeconomic status and lower education also led to more pandemic brain aging. Still, it's not how you look; it's how you feel. Do older-looking brains on brain scans function worse? The study doesn't offer much support for this. Cognitive testing found no compelling relationship between changes in brain age and changes in various tests of cognitive ability across the entire cohort. There did seem to be some relationship among those infected with COVID-19: They did worse on cognitive tests if their brains had aged more than expected. But I'm often wary of signals like this that appear in a very particular subgroup. Leaving the realm of data and stepping squarely into the land of speculation, I think what we are likely seeing here is that the pandemic was a population-wide neurologic stressor. The isolation, the anxiety, and the lack of cognitive stimulation led our brains to atrophy a bit. It does not seem that this is a direct result of viral infection, though again, we don't have data on people with more severe COVID-19. The big question is, what happens next? Now that we are reintegrated with society, back at work, and using our brains a bit more, will they grow younger again? It remains to be seen. But if the pandemic-induced gray in my hair is any indicator, there may be no going back.

COVID-19 Made Our Brains Age Faster
COVID-19 Made Our Brains Age Faster

Time​ Magazine

time6 hours ago

  • Time​ Magazine

COVID-19 Made Our Brains Age Faster

COVID-19 is leaving all kinds of legacies on our health, both on our bodies and our brains. In a study published July 22 in Nature Communications, researchers report that living through the pandemic aged our brains—whether or not you were infected with COVID-19. To investigate COVID-19's impact on the brain, researchers looked at brain scans from 1,000 people during and before the pandemic. They compared these to brain scans from other people taken during "normal" times as a model for typical brain aging. Led by Ali-Reza Mohammadi-Nejad from the University of Nottingham School of Medicine in the U.K., the researchers looked at measures like brain function, gray and white matter volume, a person's cognitive skills, and their chronological age. Gray matter is critical for memory, emotions, and movement, while white matter is essential for helping nerves transmit electrical signals. The pandemic-era brains aged about 5.5 months faster compared to the brains of those studied before the pandemic. The accelerated aging was documented in people who had COVID-19 infections as well as those who didn't, which strongly suggests that pandemic-related factors other than biological or virus-driven ones—like high stress—were also at work. In fact, the changes in gray and white matter were similar in people who were and were not infected. 'This finding was interesting and rather unexpected,' says Mohammadi-Nejad. Other studies have already shown that the COVID-19 virus can change the brain for the worse, but "we found that participants who simply lived through the pandemic period, regardless of infection, also showed signs of slightly accelerated brain aging. This highlights that the broader experience of the pandemic—including disruptions to daily life, stress, reduced social interactions, reduced activity, etc.,—may have had a measurable impact on brain health.' Read More: What to Know About the New COVID-19 Variant XFG The impact of the pandemic seemed to be greater in certain groups—notably men, the elderly, and people with more compromised health, lower educational status and income, or unstable housing. People with less stable employment had an average of five months of additional brain aging compared to those with higher employment status, while poorer health added about four months of increased brain age compared to better health. However, only people infected with COVID-19 showed drops in cognitive skills. But the fact that those who weren't infected during the pandemic also showed accelerated aging reflects the need to acknowledge the broader health effects of the pandemic beyond the obvious physical metrics on which doctors tend to focus. 'Brain health can be influenced by everyday life activities, and major societal disruptions—like those experienced during the pandemic—can leave a mark even in healthy individuals,' Mohammadi-Nejad says. 'This adds to our understanding of public health by reinforcing the importance of considering mental, cognitive, and social well-being alongside traditional physical health indicators during future crisis-response planning.' While the study did not explore specific ways to address brain aging, he says that strategies known to maintain brain health, such as a healthy diet, exercise, adequate sleep, and social and cognitive interactions are important, especially in the context of stressful circumstances such as a pandemic. 'Whether these can reverse the specific changes we observed remains to be studied,' he says.

Nano Zeolite Sieves Drive Growth in Energy, Water, and Medical Sectors
Nano Zeolite Sieves Drive Growth in Energy, Water, and Medical Sectors

Time Business News

time14 hours ago

  • Time Business News

Nano Zeolite Sieves Drive Growth in Energy, Water, and Medical Sectors

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