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279-year-old mummy reveals never-before-seen method of preserving human body

279-year-old mummy reveals never-before-seen method of preserving human body

India Today05-05-2025

For decades, scientists and researchers have been studying how ancient cultures preserved human bodies to the extent that they still have DNA intact. Now, they have hot upon a mysterious process in a small Austrian village.Researchers have analysed a mummy from a small Austrian village, which provided insights into little-known mummification techniques and allowed them to identify the body that has been dead for 279 years.advertisementThe unusually well-preserved mummy in the church crypt of St Thomas am Blasenstein is the corps of a local parish vicar, Franz Xaver Sidler von Rosenegg, who died in 1746.
"Our investigation uncovered that the excellent preservation status came from an unusual type of embalming, achieved by stuffing the abdomen through the rectal canal with wood chips, twigs and fabric, and the addition of zinc chloride for internal drying,' Dr Andreas Nerlich, a pathologist at Ludwig-Maximilians-Universitat and first author of the Frontiers in Medicine article said.
External appearance of the mummy from the ventral (A) and dorsal side (B) showing a completely intact body wall. Credit: Andreas Nerlich.
advertisementCT scanning and extensive analysis revealed that the mummy's upper body was fully intact, whereas the lower extremities and head showed considerable post-mortem decay.A variety of foreign materials were discovered in the abdominal and pelvic cavity, the team identified wood chips from fir and spruce, fragments of branches, as well as different fabrics, including linen, hemp, and flax. All these materials were easily available at that time and in that region.'Clearly, the wood chips, twigs, and dry fabric absorbed much of the fluid inside the abdominal cavity,' said Nerlich.Researchers noted that this way of embalming is different to better-known methods where the body is opened to prepare it. Here, however, the embalming materials were inserted via the rectum.'This type of preservation may have been much more widespread but unrecognized in cases where ongoing postmortal decay processes may have damaged the body wall so that the manipulations would not have been realized as they were,' Nerlich pointed out.A small glass sphere with holes on both ends – perhaps an application to the fabric of monastic origin was also discovered inside the mummy. The mummy was long rumoured to belong to Sidler, but the origin of these rumours is unknown. It was, however, only the current investigation that provided certainty as to its identity. analyses showed that the mummy died most likely aged between 35 and 45 years old and most probably between 1734 and 1780.advertisementThe lack of major signs of stress on the skeleton fits the life of a priest without hard physical activity. There also was evidence of a long-term smoking habit, and lung tuberculosis towards the end of his life.

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Scientists finally solve the 160-year-old problem of Mendel's peas
Scientists finally solve the 160-year-old problem of Mendel's peas

The Hindu

time27-05-2025

  • The Hindu

Scientists finally solve the 160-year-old problem of Mendel's peas

Feng, C., Chen, B., Hofer, J. et al, 'Genomic and genetic insights into Mendel's pea genes', Nature (2025). In 1856, an Austrian monk named Gregor Johann Mendel began experimenting on pea plants to understand how traits are passed on from parent to offspring. He worked diligently for eight years, experimenting on more than 10,000 plants, before presenting his results in a meeting of the Brunn Natural History Society in 1865. His work was published the following year in a small journal of the society called Proceedings of the Natural History Society of Brno. His findings received very little attention at the time. Mendel died in 1884, unaware that his work would go on to become the foundation of the field of genetics. Crossing plants In 1900, 16 years after Mendel's death, three scientists — Hugo de Vries, Carl Correns, and Erich von Tschermak — independently rediscovered his work. They realised that Mendel had answered the question of whether some traits of the parents are passed on to their offspring more frequently than others. Mendel had studied the inheritance patterns of seven traits in pea plants, each with two clearly distinguishable forms. For example, one of the traits he examined was seed shape, where the seeds were either round or wrinkled. Mendel observed that when he crossed plants with opposing traits, one form would consistently dominate the other. That is, crossing plants with round seeds and those with wrinkled seeds always produced first-generation offspring with round seeds. Interestingly, when two such first-generation plants were crossed, the wrinkled form reappeared, though at a much lower frequency. Mendel found that the ratio of round to wrinkled seeds in this second generation was consistently around 3:1. For reasons unknown at the time, the round form appeared to 'dominate' the wrinkled form, and this same pattern held true for all seven traits he studied, the remaining six being: seed colour (yellow or green), flower colour (purple or white), pod shape (inflated or constricted), pod colour (green or yellow), flower position (along the stem or at the end), and plant height (tall or short). Predictability of inheritance Mendel's observations became the basis for understanding how traits are inherited through discrete units of heredity, which we now call genes. Scientists later realised that for each trait, an organism carries two versions of a gene, one inherited from each parent. These versions, known as alleles, can differ in their effect on the offspring's appearance. In many cases, one allele masks the effect of the other, explaining why only one form of the trait appeared in first-generation plants. This work provided the first clear evidence that inheritance follows predictable patterns — an insight that eventually led to the development of the chromosome theory of inheritance, the identification of genes as specific units on chromosomes, and paved the way for the emergence of modern genetics. However, the original question of what genetic differences gave rise to the two forms of each of the seven traits Mendel studied remained unanswered for a long time. Although efforts to identify the genetic locations involved had begun to make progress by 1917, it took the scientific community another 108 years to fully understand why Mendel observed what he did. Mountain of information A paper published in Nature on April 23, has now identified the genetic factors responsible for the final three traits, that had remained unresolved, while also uncovering additional alleles involved in the four traits that were previously characterised. The team achieved this by selecting more than 697 well-characterised variants of the pea plant and sequencing the total DNA content of all these plants using a technique called next-generation sequencing. This resulted in almost 60 terabases of DNA sequence information. That's the equivalent of nearly 14 billion pages of text, or a stack of A4 sheets stretching 700 km into the sky. The answer to the problem of Mendel's traits was buried within this colossal mountain of information. Opening new doors The authors of the study analysed this data to create a comprehensive map so that they could begin searching for patterns. This revealed several interesting findings. First, while it is well accepted that the genus Pisum, to which the pea plant belongs, has four species, genetically they appear to form eight groups. 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Specifically, they found that a deletion of a segment of DNA present before a gene called ChlG disrupts the synthesis of chlorophyll, the pigment that gives plants their green colour, resulting in the yellow pods. Changes near the MYB gene and changes in the CLE-peptide-encoding genes together resulted in the constricted pod trait. And a small deletion in the DNA containing the CIK-like-coreceptor-kinase gene, along with the presence of another DNA segment called a modifier locus, was associated with the flowers appearing at the end of the stem. Finally, the map that the team generated shows multiple other genome-wide interactions that Mendel did not study, including 72 agriculturally relevant traits such as the architectures of the seed, pod, flower, leaf, root and plant. While closing the doors on this 160-year-old scientific mystery, the scientists involved in the study have paved the way to something greater. The depth of genetic information they had uncovered holds enormous promise for future research, with a lot of implications for increasing crop yield, enhancing disease resistance, and improving environmental adaptations. It is incredible to think that all of this owes its origin to a 19th century monk, who, while tending to his garden, chose to ask why. Arun Panchapakesan is an assistant professor at the Y.R. Gaitonde Centre for AIDS Research and Education, Chennai.

Johann Strauss' The Blue Danube, famously used in Squid Game, will be beamed to space to mark its 50th anniversary
Johann Strauss' The Blue Danube, famously used in Squid Game, will be beamed to space to mark its 50th anniversary

Mint

time26-05-2025

  • Mint

Johann Strauss' The Blue Danube, famously used in Squid Game, will be beamed to space to mark its 50th anniversary

Johann Strauss II's iconic orchestral waltz The Blue Danube, once the sonic backdrop for both Stanley Kubrick's 2001: A Space Odyssey and the Netflix megahit Squid Game, is about to reach its most literal destination yet: outer space. In a bold and poetic gesture, the European Space Agency (ESA) will beam The Blue Danube into the cosmos this Saturday to mark two landmark anniversaries—the 50th year since ESA's formation and 200 years since the birth of the Austrian composer Strauss himself. The Vienna Symphony Orchestra will perform the piece live in Austria, while a powerful radio antenna based in Spain simultaneously broadcasts it beyond Earth's atmosphere. Despite its deep cultural association with space—most memorably accompanying a balletic docking scene in 2001: A Space Odyssey—The Blue Danube was glaringly absent from NASA's 1977 Voyager Golden Records. These interstellar time capsules included 27 musical tracks from around the world, but no waltz from Strauss made the cut. 'The absence of the most famous of all waltzes from the 1977 Voyager Golden Record is a cosmic mistake,' said Norbert Kettner, director of the Vienna Tourist Board, which is partnering with ESA for the occasion. 'We are delighted to correct it—better late than never.' The waltz has recently found a new generation of admirers thanks to the Emmy-winning Korean drama Squid Game, where it underscored key moments with eerie calm in contrast to the brutal on-screen events. Its use in the hit series has reignited interest in the piece, especially among younger audiences who may have never encountered it in concert halls or cinema before. While there's no alien audience confirmed (yet), the symbolic act of broadcasting The Blue Danube carries both cultural and scientific weight. As the waltz floats once again among stars - this time literally - Strauss' dreamy melodies will serve as a sonic ambassador for Earth's elegance and creativity.

Why time goes only forward: Science of entropy and irreversibility
Why time goes only forward: Science of entropy and irreversibility

Indian Express

time06-05-2025

  • Indian Express

Why time goes only forward: Science of entropy and irreversibility

Why do we grow older but never younger? Why can't a shattered glass come back together by itself? Why don't events 'unhappen'— we remember yesterday's mistakes but have no 'recollection' of tomorrow's triumphs? These everyday puzzles all share a single answer: time has a built-in direction, and it points toward increasing disorder. At the heart of this 'arrow of time' is entropy, a measure of how many ways the tiny parts of a system — molecules, atoms, or bits of information — can be arranged while looking the same to us. Low-entropy states, like a young face or an unbroken glass, are highly specific and few. High-entropy states, like wrinkles or broken shards, are vastly more numerous. Just as it's far easier to knock over a set of dominoes than to stand each one back up, nature almost always moves toward the more likely, disordered arrangements. To see this in action, imagine a child's playroom. A perfectly neat room — with every toy in its place — is just one arrangement. A messy room — toys scattered everywhere — can occur in millions of different ways. If left alone, the room stays messy, because disorder is the default. Restoring order requires focused effort. Pour cream into coffee and watch the two swirl together. You never see them separate themselves again, because there are astronomically more ways for cream and coffee molecules to be mixed than to form those initial graceful ribbons. Likewise, when ice melts in a drink or perfume drifts through a room, the process naturally flows toward mixed and spread-out states. The arrow of time In the mid-1800s, engineers building steam engines noticed something puzzling: heat naturally flowed from hot to cold, and no mechanism could ever fully reverse that flow. German physicist Rudolf Clausius captured this as the Second Law of Thermodynamics — heat moves one way, and that 'one way' is the same direction that marks the passage of time. Austrian theoretical physicist Ludwig Boltzmann transformed this empirical law into a deep principle. He showed that it arises from simple counting: there are vastly more ways for particles to be jumbled than to be neatly arranged. If you shuffle a deck of cards, there are 8×10⁶⁷ possible orders, but only one correct, sorted order. Random shuffles almost never restore order. Heat flow and molecular motion follow the same principle: systems randomly explore all possible configurations, and the disordered ones vastly outnumber the ordered. Because nature overwhelmingly prefers the jumble, heat flows from hotter to colder regions and never the other way around. With this, time itself gains its irreversible arrow. How entropy works Entropy, in Boltzmann's view, measures the number of ways a system can be arranged at the microscopic level while looking the same on the macroscopic level. Low-entropy states — like a tidy room or separate layers of cream and coffee — correspond to very few arrangements. High-entropy states — like a messy room or uniformly mixed coffee — correspond to enormously many arrangements since there are numerous ways in which to mix coffee or strew toys around in a room. When a system evolves, it almost certainly moves toward the high-entropy configurations because there are simply far more of them. That statistical tendency underlies every one-way process we observe: ice melting, perfume spreading, memories forming. More Everyday Examples ⏳Spilled Milk: Once milk mixes with cereal, individual milk molecules have scattered in so many possible ways that they never all return to their original spots in the bowl. ⏳Aging: Our cells and proteins gradually accumulate tiny random changes. Reversing those exact changes — making us younger — would require every molecule in our body to retrace its steps perfectly, a statistical impossibility. ⏳Engines and Refrigerators: Every real engine spits out waste heat. That 'lost' heat represents energy spread into countless random molecular motions. Trying to capture and reuse it all would demand reorganizing those trillions of motions into a single, precise pattern — another statistical miracle that never happens. Practical Payoffs Understanding entropy isn't just academic. It guides engineers in designing more efficient engines and refrigerators and informs computer scientists on how to manage information—and heat — in data centers. In medicine, it helps researchers grasp how cells break down and why aging happens, suggesting ways to slow or detect that process. From Boltzmann to the Cosmos Boltzmann famously wrote entropy as S = k · ln W, where W counts the number of ways atoms can be arranged. In this view, entropy grows because W typically increases as systems evolve. On cosmic scales, the universe began in an extraordinarily low-entropy state at the Big Bang—matter and energy packed into a highly ordered form. Since then, gravity and nuclear reactions have driven entropy ever higher, from star formation to black hole mergers, each step opening vast new realms of disorder. Even black hole physics uses entropy to probe the ultimate limits of information and evaporation. Why It Matters So the next time your morning toast browns, your coffee cools, or your instinct tells you to stop spilling that glass of water, you're witnessing entropy in action. Time's arrow isn't a mysterious force; it's simply the clock built into the countless ways disorder outweighs order. And yes, just like you can't un-toast that bread or un-spill the milk, you can't rewind the day — so you might as well make the most of every moment.

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