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Tear-Based Biomarker Identified for early detection of keratoconus

Tear-Based Biomarker Identified for early detection of keratoconus

Time of India28-05-2025

New Delhi: Delhi-based biotech company
Vgenomics
has partnered with Dr. Shroff's Charity Eye Hospital to validate and commercialize a
tear-based biomarker
,
VSP-2224
, for the
early detection of keratoconus
, a progressive eye disorder affecting the cornea.
VSP-2224, identified in tear fluid using Vgenomics'
AI-based discovery platform
RgenX-LENS, may help detect the disease earlier, before visible symptoms emerge.
Clinical validation of VSP-2224 is underway. The biomarker will also be featured in OcuTear, a rapid diagnostic panel Vgenomics is developing for ocular surface diseases.
Commenting on the development, Dr Anil Tiwari said, 'This partnership enables us to translate a tear-based biomarker into a clinically viable diagnostic test, with the potential to further develop it into targeted therapeutics.'

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