'I'm a gastroenterologist – this common painkiller can cause two major health issues'

Daily Mirror

01-05-2025

Dr Saurabh Sethi, who posts on social media about various health topics, issued a warning to the millions who take a popular painkiller. Here's what they had to say
A gastroenterologist has issued a stark warning to the millions who regularly take a common pill – as overuse can lead to two significant health problems. Dr Saurabh Sethi, known for his online health advice, stated that he would be cautious taking this medication due to its potential risks.
Overconsumption of ibuprofen can have detrimental effects on the body. In fact, many people are unaware of the harm it can cause, prompting Dr Sethi to share some expert guidance. He revealed: "75% of people who take them regularly develop gut inflammation, and one in four can develop ulcers. I perform endoscopies regularly, and see these ulcers first hand.
‌
"NSAIDs reduce bloodflow to the gut, which can harm its lining. I've seen young, otherwise healthy people, come in with gut damage so severe they've ended up in the ER just because they did not know the risk of these medications.
‌
"If you're taking these medicines more than a couple of times a month, here are three things you can do. First, talk to your doctor about alternatives."
He added: "Second, talk to your doctor about using a stomach protecting medication. And third, take these medicines with food to minimise the risk of damage to the gut lining."
It's worth noting that regular or high-dose consumption of ibuprofen can cause ulcers. This is due to its ability to reduce the production of prostaglandins, which play a crucial role in protecting the stomach lining.
Ibuprofen, part of the nonsteroidal anti-inflammatory drugs (NSAIDs) family, blocks an enzyme called cyclooxygenase (COX), which is crucial in prostaglandin production. Prostaglandins are key players in preserving the stomach lining's defence against acid and digestive fluids.
What is ibuprofen?
‌
It's an NSAID that people reach for to ease pain and bring down fevers. Common ailments like headaches, dental pain, muscular strains, arthritis, and period pains are all on its hit list.
Not only does it relieve pain, but its anti-inflammatory abilities help reduce inflammation and swelling. The pill can usually be taken by people aged over 17, but there are red flags, such as history of allergic reactions to NSAIDs or if you're expecting a baby.
While the pill helps many – and often isn't anything to worry about – it's always wise to chat with your GP before popping ibuprofen, just to rule out any reasons why you shouldn't.
‌
The NHS has outlined some potential side effects worth noting. It cautions: "Ibuprofen can cause ulcers in your stomach or gut, especially if you take it by mouth for a long time or in big doses. If you need to take it for a long time your doctor may also prescribe a medicine to help protect your stomach."
Common side effects of oral ibuprofen, which can affect more than one in 100 people, include headaches, dizziness, nausea, vomiting, flatulence or indigestion.
If these symptoms persist, it's crucial to consult your doctor. The NHS also advises that you should immediately contact a doctor, or dial 111, and cease taking ibuprofen if you experience:
Black poo or blood in your vomit – these signs can indicate bleeding in your stomach
Swollen ankles, blood in your pee or not peeing at all – these signs can indicate a kidney problem