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Beijing Review: Future-Facing Partnership

Beijing Review: Future-Facing Partnership

Yahoo15-05-2025

BEIJING, May 14, 2025 /PRNewswire/ -- Just as a ship is powered by its sails, people are inspired by their hearts. On November 15, 2024, President Xi Jinping quoted this Latin American proverb in his written speech delivered at the Asia-Pacific Economic Cooperation CEO Summit. He called on all nations to enhance solidarity and cooperation, jointly stand up to global challenges and form a mighty force for the common prosperity of the world and a brighter future for humanity.
Amid shifting international dynamics, the Global South, including China and countries in Latin America and the Caribbean (LAC), is rising with growing strength and influence. China-LAC relations have entered a new phase, setting a new benchmark for South-South cooperation.
In July 2014, during his visit to Brasília, capital of Brazil, Xi attended the China-LAC Countries Leaders' Meeting, where he first proposed building a China-LAC community with a shared future. Together with the attending leaders, he jointly announced the establishment of the Forum of China and Community of Latin American and Caribbean States (CELAC).
In January 2015, the First Ministerial Meeting of the China-CELAC Forum was held in Beijing. This was the beginning of overall cooperation between China and LAC countries. "The China-CELAC Forum, a young seedling in our eyes, needs the dedication and cultivation of both sides for it to grow bigger and stronger," Xi said at the opening ceremony.
Today, that once-tender seedling has grown into a flourishing tree—lush, robust and thriving. From vision to reality, from concept to concrete action, the China-CELAC Forum has become the leading platform for advancing overall cooperation between China and LAC countries.
Over the past decade, the two sides have continuously deepened political mutual trust and expanded practical cooperation. Panama, the Dominican Republic, El Salvador, Nicaragua and Honduras have established or resumed diplomatic ties with China. The latter has firmly held its position as the LAC's second largest trading partner, while Chile, Peru, Costa Rica, Ecuador and Nicaragua have all become China's free trade partners.
In November 2024, the Chancay Port in Peru officially commenced operations. This milestone celebrates the birth of a new land-sea corridor between Asia and LAC countries in the new era.
Over the past decade, China and LAC nations have remained committed to safeguarding world peace and promoting shared development. In May 2024, China and Brazil jointly issued the Common Understandings on Political Settlement of the Ukraine Crisis, which received positive responses from more than 110 countries.
The Fourth Ministerial Meeting of the China-CELAC Forum took place in Beijing on May 13. China has expressed its readiness to work with partners in the region to promote progress in building a China-LAC community with a shared future. Together, they seek to address global challenges, promote reforms in global governance and contribute wisdom and strength to maintaining world peace and stability.
In the spirit of the proverb "just as a ship is powered by its sails, people are inspired by their hearts," the China-LAC community with a shared future is poised for a steady and prosperous voyage, charting a new course for bilateral relations.
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Registrational Study Led by MSD NSCLC not achieving a pCR after neoadjuvant therapy followed by surgery. NSCLC expressing PD-L1 >50% pre-treated NSCLC with EGFR mutations or other genomic alterations EGFR-mutated, advanced non-squ NSCLC progressed on prior EGFR-TK metastatic sg NSCLC About sac-TMT Sac-TMT, a core product of the Company, is a novel human TROP2 ADC in which the Company has proprietary intellectual property rights, targeting advanced solid tumors such as NSCLC, BC, gastric cancer (GC), gynecological tumors, among others. Sac-TMT is developed with a novel linker to conjugate the payload, a belotecan-derivative topoisomerase I inhibitor with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases KL610023 intracellularly. KL610023, as a topoisomerase I inhibitor, induces DNA damage to tumor cells, which in turn leads to cell-cycle arrest and apoptosis. In addition, it also releases KL610023 in the tumor microenvironment. Given that KL610023 is membrane permeable, it can enable a bystander effect, or in other words kill adjacent tumor cells. In May 2022, the Company licensed the exclusive rights to MSD (the tradename of Merck & Co., Inc., Rahway, NJ, USA) to develop, use, manufacture and commercialize sac-TMT in all territories outside of Greater China (includes Mainland China, Hong Kong, Macao, and Taiwan). To date, two indications for sac-TMT have been approved and marketed in China for the treatment of adult patients with unresectable locally advanced or metastatic TNBC who have received at least two prior systemic therapies (at least one of them for advanced or metastatic setting) based on the OptiTROP-Breast01 study and EGFR mutation-positive locally advanced or metastatic non-squamous NSCLC following progression on EGFR-TKI therapy and platinum-based chemotherapy based on the OptiTROP-Lung03 study. Sac-TMT became the first domestic ADC with global intellectual property rights to be fully approved for marketing. It is also the world's first TROP2 ADC to be approved for marketing in a lung cancer indication. In addition, two new indication applications for sac-TMT for the treatment of adult patients with EGFR-mutant locally advanced or metastatic NSCLC who progressed after treatment with EGFR-TKI therapy and with unresectable locally advanced, metastatic hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) BC who have received prior endocrine therapy and other systemic treatments in the advanced or metastatic setting were accepted by the National Medical Products Administration (NMPA), and were reviewed via the priority review and approval process. As of today, the Company has initiated 8 registrational clinical studies in China. MSD has initiated 14 ongoing Phase 3 global clinical studies of sac-TMT as a monotherapy or with pembrolizumab or other agents for several types of cancer. These studies are sponsored and led by MSD. About Kelun-Biotech Kelun-Biotech( a holding subsidiary of Kelun Pharmaceutical ( which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. The company focuses on major disease areas such as solid tumors, autoimmune, inflammatory, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. The Company is committed to becoming a leading global enterprise in the field of innovative drugs. At present, the Company has more than 30 ongoing key innovative drug projects, of which 3 projects have been approved for marketing, 1 project is in the NDA stage, and more than 10 projects are in the clinical stage. The company has established one of the world's leading proprietary ADC platforms, OptiDC™, and has 1 ADC project approved for marketing, 1 ADC project in NDA stage, and multiple ADC and novel coupled drug products in clinical or preclinical research stage. For more information, please visit Media: klbio_pr@ View original content to download multimedia: SOURCE Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

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