Many US Cities Are Sinking. But In Texas, It's Worse
Cities across the US are sinking, and the problem is most pronounced in Texas, according to a new study.
The research, which examined 28 cities and was published in science journal Nature on Thursday, found all of them were affected by subsidence, a geological phenomenon that increases their exposure to disasters like floods and earthquakes. Urban centers in Texas are among those sinking the most and have some of the largest numbers of buildings facing potential dangers, according to the report.
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Associated Press
28 minutes ago
- Associated Press
Matter Neuroscience announces collaboration with Stanford Medicine combining Matter protocol with real-time fMRI neurofeedback to support emotion-based interventions in depression
This collaboration sets out to explore whether using the Matter Neuroscience protocol combined with real-time neurofeedback can influence emotional brain networks relevant to depression. PALO ALTO, Calif., June 3, 2025 /PRNewswire/ -- Matter Neuroscience is pleased to announce a collaboration with Stanford Medicine's Psychiatry and Behavioral Sciences Department. The controlled, multi-arm study will enroll at least 210 depressed patients with the objective to significantly reduce clinical endpoints using real-time 7T fMRI neurofeedback in combination with the Matter protocol selectively activating key brain areas hosting distinct positive emotions. The clinical endpoints are paralleled with several molecular, emotional and behavioral biomarkers. If successful, the findings can be integrated into a full-scale clinical trial with the potential to inform future non-pharmaceutical curative therapies for depression. Professor Nolan Williams, M.D. an Associate Professor of Psychiatry and Behavioral Sciences at Stanford University and Director of the Stanford Brain Stimulation Lab will serve as the Principal Investigator on the study. 'This study allows us to investigate how targeted emotion training, guided by real-time fMRI, may influence mood-related brain circuits,' said Dr. Williams. 'What makes this particularly interesting is the opportunity to evaluate both the neural mechanisms involved in emotion regulation and the feasibility of translating this approach into a deliverable treatment in the clinic or home one day.' Matter CEO Axel Bouchon shares, 'After we have seen positive effects in emotional wellbeing of healthy individuals in our studies in the past 4-5 years, it is just one of the most exciting studies I have witnessed in my career. Ultimately, we try to use the latest advancements in MRI technology and the patients' good memories as a personalized medicine to reduce, maybe permanently cure, their depressive symptoms.' About Matter Matter Neuroscience was founded in 2019 by Axel Bouchon and Ben Goldhirsh. Matter's mission is to use neuroscience to help people live longer, healthier, happier lives. Matter Neuroscience runs a consumer technology business ( ) and a medical business addressing healthy individuals and patients, respectively. Matter is led by CEO Axel Bouchon (Moderna, Bayer, ARCH Venture Partners.) Ben Goldhirsh (GOOD Worldwide and the Goldhirsh Foundation) serves as Matter's Chairman and Head of Product. Visit to learn more about Matter. Download the Matter app, named 'App of the Day' on Apple's App Store. Follow Matter on Instagram and Tiktok for education and inspiration for living a happier life. About the Matter Protocol Matter Neuroscience and its academic partners in Maastricht and Copenhagen have conducted several research studies successfully identifying a human map for distinct positive emotions in the brain. Using this map as a directional biomarker, a team led by Professor Rainer Goebel at the Maastricht Brain Imaging Center in the Netherlands developed a protocol that allows for training and intensifying distinct human emotions using real-time fMRI neurofeedback with autobiographical memories. View original content to download multimedia: SOURCE Matter Neuroscience
Medscape
an hour ago
- Medscape
Hyperinsulinemia Linked to Abnormal Uterine Bleeding
Hyperinsulinemia appears to have an early association with common causes of abnormal uterine bleeding (AUB), particularly in women with obesity, a preliminary study in Menopause found. Although preliminary, the study data suggested the opportunity for future research on potential relationships between cardiovascular disease risk factors and gynecologic disease. 'Many studies and organizational bodies have examined and asserted a relationship between polycystic ovarian syndrome (PCOS) and elevated insulin levels,' wrote investigators led by Andrea C. Salcedo, DO, MPH, of the Department of Obstetrics and Gynecology at Loma Linda University in Loma Linda, California. They noted that AUB is the most common reason for benign gynecologic consultation in the United States. Andrea C. Salcedo, DO, MPH 'After over 15 years of clinical practice , I started realizing there were several patterns in women who presented with irregular or heavy periods. Many were self-referred or sent by their primary care providers to see me to evaluate for female hormone problems,' Salcedo told Medscape Medical News . 'The majority were not in perimenopause, but they had similar risk factors for cardiovascular disease, such as obesity, hypertension, and migraine headaches.' Salcedo began to wonder whether healthcare providers are recognizing abnormal periods in reproductive age as a cardiovascular risk and using them to educate women on prevention rather than solely treating them medically or surgically. 'I believe that the theory of the uterus as an 'end organ' that receives inflammation in the same way as the heart and kidneys do in cardiovascular disease helps explain to the patient the reasons for heavy or irregular periods.' The study findings came as no surprise to her: 'They confirmed the patterns I was seeing clinically.' Hyperinsulinemia is associated with smooth blood vessel inflammation in the peripheral circulation. 'What is often under-recognized is that the uterus is made of these same blood vessels.' When the uterus is on the receiving end of inflammation, the blood vessels are damaged and do not function appropriately. The result can be uterine fibroids or heavy periods. The gynecologic expression of this inflammation can vary from person to person, she added. The Study This exploratory cross-sectional analysis of the association between hyperinsulinemia and biomarkers of metabolic syndrome in reproductive-aged women with AUB was designed to motivate future hypothesis-driven research. It was conducted from June 2019 to August 2023 at a single institution's outpatient gynecology clinics. A total of 205 premenopausal women aged 18-54 years were enrolled, including 116 with AUB and 89 control individuals with normal menstrual cycles. Approximately 40% in each group were identified as Hispanic. Participants underwent assessment for fasting insulin and additional markers of metabolic syndrome, including body mass index (BMI), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and waist-to-hip ratio. Among the findings: • Hyperinsulinemia, the main effect of interest, was a significant predictor of AUB, affecting 44.0% of the AUB group vs 33.7% of the control group, with an odds ratio of 3.0 (95% CI, 1.372-6.832; P = .0085). • Hypertension, LDL, HDL, smoking, migraines, and polyps or fibroids were all significantly associated with AUB and identified as confounders. Chronic hypertension was identified in 26% of the AUB group vs 12% of the control group. • Interestingly, including BMI in the model diminished the significance of hyperinsulinemia, suggesting overlapping or mediating pathways, the authors said. • Among metabolic markers, LDL levels were similar between groups, while HDL levels were lower in women with AUB (54.0 vs 60.0 mg/dL). • There was a nonsignificant intergroup difference in triglycerides (82.0 vs 73.5 mg/dL) and total cholesterol levels (169.0 vs 172.5 mg/dL). • Migraines were more prevalent in the AUB group (31.0% vs 11.2%), as were polyps or fibroids (45.7% vs 9.6%). Commenting on the study but not involved in it, Maureen Whelihan, MD, a gynecologist at the Center for Sexual Health and Education and Elite GYN Care of the Palm Beaches in Greenacres, Florida, called the study an interesting one, 'suggesting that before we see the effects of PCOS, a diagnosis of hyperinsulinemia can be made and managed and that hyperinsulinemia has a direct effect on microinflammatory injury to the uterus.' Maureen Whelihan, MD In her practice, women with insulin resistance and PCOS have major infertility issues. 'About 85% are obese and have lipid disorders. While this study indicates we can make a diagnosis earlier by evaluating fasting insulin, the question is, 'then what?'' she said. The ultimate remedy is diet and lifestyle modification. 'The minute patients understand they must eliminate starch and sugar to lower insulin levels and move their body a little, we lose them,' she said. 'They want a quick fix and nothing that requires them to make difficult decisions and drastic modifications. This is the hard part! We can teach them the pathophysiology all day, but they have to commit to a permanent change in the way they approach diet and exercise.' While the study findings are exploratory and preliminary, Salcedo said, they suggest that abnormal periods may have predictive value. 'In many cases, elevated fasting insulin levels, above 10 µU/mL, could be an early sign of cardiovascular and diabetes disease risk.' In this study, elevated insulin levels were associated with AUB, particularly among those with obesity. 'Therefore, when a patient sees her healthcare provider for irregular periods, it could be an excellent opportunity to discuss the known association of menstrual problems with [cardiovascular] risk factors.' Larger, longitudinal studies are needed, however, to confirm the causal mechanisms, Salcedo said.
Yahoo
an hour ago
- Yahoo
Woman dies of brain-eating amoeba after using tap water in nasal rinse device
A woman in Texas has died after contracting a fatal brain amoeba from contaminated water. The patient, 71, had used a nasal irrigation device filled with unboiled tap water from an RV's water faucet, according to an alert from the U.S. Centers for Disease Control and Prevention (CDC). The "previously healthy" woman was staying at a local campground at the time, the agency stated. Dangerous Fungus Could Spread To Parts Of Us, Researchers Claim Within four days of using the nasal rinse, the woman developed "severe neurologic symptoms," including fever, headache and altered mental status. The patient was treated for a potential infection of primary amebic meningoencephalitis (PAM), a rare, deadly brain infection caused by Naegleria fowleri, also known as the brain-eating amoeba. Read On The Fox News App Despite treatment, the woman began having seizures and died eight days after symptoms began. Testing of the patient's cerebrospinal fluid confirmed she had contracted N. fowleri, according to the CDC. "This case reinforces the potential for serious health risks associated with improper use of nasal irrigation devices, as well as the importance of maintaining RV water quality and ensuring that municipal water systems adhere to regulatory standards," the health agency stated. Naegleria fowleri can also be a risk when swimming in fresh water. It is more prevalent during hotter months, as the amoeba grows best in high air and water temperatures. Fox News Digital previously spoke with Tammy Lundstrom, chief medical officer and infectious disease specialist for Trinity Health in Michigan, about the risks of infection. "The risk of brain-eating amoeba is very low," she said. "Fewer than 10 people in the U.S. every year get infected — but unfortunately, most cases are fatal. There are only a handful of survivors of known cases." The death rate for Naegleria fowleri exceeds 97%, per the CDC. The initial symptoms of PAM usually begin about five days after exposure, but they can be noticed sooner. Early signs usually include headache, nausea, fever and/or vomiting, the CDC's website states. As the infection progresses, people may experience confusion, stiff neck, disorientation, hallucinations, seizures and coma. Dangerous Fungus Spreading In Us Hospitals Has 'Rapidly Increased' "People usually start to feel ill one to 12 days after water exposure," Lundstrom said. "Early symptoms should prompt a medical evaluation, as they are also signs of bacterial meningitis." Death can occur anywhere between one and 18 days of infection, at an average of five days. To prevent contracting the fatal infection, the CDC recommends using "distilled, sterile or boiled and cooled tap water for nasal irrigation," as "improperly maintained" municipal water and RV water systems carry the risk of disease. It is also best to avoid immersing your head in the water when swimming in summer, Lundstrom told Fox News Digital. "Infection occurs when water harboring the amoeba goes up a person's nose, usually during swimming," she said. "It is not known why some people get infected and others, even swimming companions, do not." Drinking contaminated water does not present a risk, and the infection does not spread from one person to another, Lundstrom added. Because the amoeba is found in soil, the CDC also recommends avoiding stirring up the sediment at the bottom of lakes, ponds and rivers. When a patient has been diagnosed with a brain-eating amoeba, treatment usually includes a variety of antifungal medications, as well as antibiotics like rifampin and azithromycin, according to Lundstrom. Click Here To Sign Up For Our Health Newsletter Miltefosine, a newer antifungal drug, has been shown to kill Nagleria fowleri in laboratory tests and was used to treat some surviving patients, the CDC states on its website. "However, the effect of all of these drugs on actual infected people is unknown due to the high fatality rate," Lundstrom noted. Those who experience sudden headache, fever, stiff neck or vomiting — especially if they have recently been swimming in warm freshwater — should seek immediate medical attention, the CDC recommends. For more Health articles, visit Despite the infection's high fatality rate, Lundstrom emphasized the rarity of cases. "Millions of people enjoy swimming every summer, but only a few become infected," she article source: Woman dies of brain-eating amoeba after using tap water in nasal rinse device
