Latest news with #'sFoundation
Medscape
25-07-2025
- Health
- Medscape
Fast Five Quiz: Sjögren Disease Management
Learn more about ocular dryness in Sjögren disease. B cells have been shown to significantly impact the pathogenesis of primary Sjögren disease. However, B-cell targeted therapies are generally considered in severe, refractory cases, or in patients with systemic involvement. Specially, the EULAR recommends considering B-Cell targeted therapies only in severe, refractory systemic disease. This is consistent with recommendations from the Sjögren's Foundation, wherein most biologic therapies are recommended for refractory cases or those with systemic involvement. Additionally, the Sjögren's Foundation specifically recommends against the use of tumor necrosis factor inhibitors to treat sicca symptoms in patients with Sjögren disease. Learn more about B-cell therapies for Sjögren disease. Pulmonary manifestations of Sjögren disease, which include interstitial lung disease, are a potentially serious complication of the disease. For patients with symptomatic cystic vocal cord lesions (bamboo nodules), the Sjögren's Foundation recommends voice therapy, inhaled corticosteroids, or intralesional corticosteroid injections. A recent review has further confirmed these approaches are most appropriate in this setting. Nebulized saline is usually recommended for patients with Sjögren disease and ' clinically relevant bronchiectasis.' Systemic corticosteroids are not usually recommended as an initial treatment in this setting; they are typically used for other pulmonary manifestations, such as interstitial lung disease and certain small airway diseases. Surgical resection is typically considered when these approaches fail and after a consultation with a laryngologist. Learn more about pulmonary manifestations in Sjögren disease. For patients with Sjögren disease and acute musculoskeletal pain, EULAR recommends limiting NSAID use to no more than 10 days at full dosage, citing evidence that one third of patients will have a rapid clinical response to short-term analgesics. For inflammatory musculoskeletal pain, the Sjögren's Foundation guidelines recommend hydroxychloroquine and/or methotrexate, progressing to corticosteroids, then leflunomide, sulfasalazine, azathioprine, and cyclosporine. EULAR also suggests hydroxychloroquine for this indication due its effectiveness in other systemic autoimmune diseases but note a pivotal RCT did not show significant benefit. As such, they emphasize nonpharmacologic management of chronic pain and note that treatment should follow general chronic pain guidance. Learn more about pain in Sjögren disease. Editor's Note: This article was created using several editorial tools, including generative AI models, as part of the process. Human review and editing of this content were performed prior to publication. Lead image: Peakstock/Science Source
MTV Lebanon
23-03-2025
- General
- MTV Lebanon
Fadlallah: Sunday, March 30, first day of Eid al-Fitr
The Sharia Office of the Grand Ayatollah Sayyed Mohammad Hussein Fadlallah's Foundation issued a statement announcing that 'Sunday, March 30, 2025, is the first day of Eid al-Fitr, based on the jurisprudential foundation of the Grand Ayatollah, relying on accurate astronomical scientific calculations that provide reassurance regarding the birth of the crescent and the possibility of seeing it." The statement added, "We ask God Almighty to make it a blessed and auspicious Eid for the Islamic nation, to accept our fasting and our deeds, and grant us in His mercy.'
National News
23-03-2025
- General
- National News
Fadlallah: Sunday, March 30, first day of Eid al-Fitr
NNA - The Sharia Office of the Grand Ayatollah Sayyed Mohammad Hussein Fadlallah's Foundation issued a statement today announcing that 'Sunday, March 30, 2025, is the first day of Eid al-Fitr, based on the jurisprudential foundation of the Grand Ayatollah, relying on accurate astronomical scientific calculations that provide reassurance regarding the birth of the crescent and the possibility of seeing it." The statement added, "We ask God Almighty to make it a blessed and auspicious Eid for the Islamic nation, to accept our fasting and our deeds, and to include us in His mercy.'
