Latest news with #Ardis


AFP
18-07-2025
- Health
- AFP
Health influencer falsely claims nicotine can cure neurological disorders
"Nicotine is not addictive. Parkinson's disease can be prevented and can be cured, and its symptoms reversed, with nicotine alone," health influencer Byran Ardis says in a video teasing an episode of the "Culture Apothecary" podcast from Alex Clark, a leading voice in the "Make America Healthy Again" movement. Ardis, whom AFP has previously fact-checked for spreading health misinformation, goes on to claim: "Nicotine is known by medical science to be a curative agent and a preventative agent for Alzheimer's. Did you know nicotine could also cure the symptoms of hypothyroidism?" He also asserts that "glioblastomas were proven in 2021 to be cured by nicotine alone." The clip has attracted tens of thousands of interactions on Instagram since May 19, 2025. Ardis's endorsement of nicotine patches continued to be shared across platforms in July, alongside other edits of the conversation, including one Clark posted on YouTube. Image Screenshot from Instagram taken July 18, 2025 But nicotine is an addictive chemical, and the only use for nicotine patches approved by the US Food and Drug Administration (FDA) is to quit smoking (archived here and here). "Don't use nicotine, other than trying to help quit smoking," Edward Levin, chief of the Neurobehavioral Research Lab at Duke University Medical Center, told AFP July 14 (archived here). He said the effect of nicotine on cognition, depression, Parkinson's or Alzheimer's "has not been proved, so it's still under investigation." Parkinson's disease In the podcast, Ardis claims nicotine by itself can prevent, cure or reverse symptoms of Parkinson's disease. Scientists are exploring nicotine's potential as a Parkinson's treatment due to the chemical's dopamine-increasing properties and the fact that smokers develop Parkinson's at a lower rate, but research has yielded mixed results (archived here). "Nicotine does potentially up the release of dopamine, and dopamine is what is impaired in Parkinson's disease. So the rationale for it is there, but the proof of it is not," Levin said. "To say flat out that it does prevent or cure Parkinson's just is not true." A 2015 study by the Parkinson's Institute concluded that nicotine could hold promise in terms of protecting against nerve degeneration, alleviating symptoms and reducing side effects of other drugs used to treat the disease (archived here). However, the study stops short of recommending nicotine as a proven treatment, saying instead that it "may represent a new disease modifying approach." A 2021 literature review published in Molecular Medicine Reports said nicotine may slow the progression of the disease by improving memory impairment and dyskinesia (archived here). Conversely, a trial supported by the Michael J. Fox Foundation showed nicotine patches did not slow the progression (archived here). "Despite some initially promising findings from animal models and correlational studies in humans, this has not translated well to clinical trials," Maggie Sweitzer, an associate professor in psychiatry and behavioral sciences at Duke University, told AFP in a July 15 email (archived here). "I am not aware of any solid evidence to support nicotine as a treatment in Parkinson's disease." Alzheimer's disease Ardis's second claim is that nicotine is "known by medical science" to be a curative and preventative agent for Alzheimer's disease. Researchers in the United States are currently investigating the effects of nicotine on mild cognitive impairment, a precursor to Alzheimer's, as part of the "Memory Improvement Through Nicotine Dosing" (MIND) study (archived here). But nicotine has not been incorporated into human treatment beyond clinical trials. A 2012 trial focused on 67 subjects concluded that nicotine led to cognitive improvement in attention, memory and processing, but it said further study would be necessary to determine if the findings were clinically important (archived here). A much larger follow-up is currently in progress, with results expected later in 2025 (archived here). Levin, a researcher on the MIND study, said despite promising findings, nicotine patches have not yet been FDA approved to protect against cognitive decline. "I can't recommend it," Levin said. "It's not FDA approved for that purpose. It's under investigation." Levin said that if nicotine patches were implemented as a treatment for Alzheimer's or other cognitive diseases, they would likely be used alongside other drugs, rather than alone. He also pushed back on Ardis's claim that it is safe to place nicotine patches on children, saying the drug is toxic from early fetal development through adolescence and can adversely impact the nervous system (archived here). Glioblastoma Ardis then claims nicotine alone was proven in 2021 to cure glioblastoma, an aggressive form of brain cancer. AFP did not find a reference with such clear proof. Instead, a 2021 paper in Pharmacological Research showed nicotine can promote the proliferation of glioblastoma cells, with nicotinic receptors potentially contributing to the tumor's aggressive behavior (archived here). The paper also discovered that drugs that block nicotinic receptors can decrease glioblastoma cell growth. An earlier literature review said smoking and other uses of tobacco and nicotine during treatment can detrimentally affect a patient's prognosis (archived here). Keyword searches did reveal a 2022 in vivo study which found that nicotine, in conjunction with lithium carbonate, can suppress and kill glioblastoma cells, although the study also warns of health risks resulting from nicotine's cytotoxicity (archived here). But such findings have not been replicated outside of in vivo cell studies, and Sweitzer said it would be difficult to study the isolated effect of nicotine on glioblastoma in a clinical setting. "It would be unethical for researchers to assign patients with glioblastomas to a treatment condition where they received 'nicotine alone' in the absence of usual standard of care, because this would deprive the patients of treatment that they would receive if they were not in the study," Sweitzer said. "In general, people should be highly skeptical about claims that something has been 'proven' in health and medicine." Lead Stories and Medical Dialogues previously debunked claims by Ardis that nicotine can cure brain tumors in as little as 72 hours. Hypothyroidism Finally, Ardis poses that nicotine could cure symptoms of hypothyroidism, a thyroid gland condition that can lead to high cholesterol and heart problems. The 2021 Molecular Medicine Reports literature review said nicotine may "activate thyroid receptor signaling pathways" to improve hypothyroidism-induced memory impairment (archived here). But Sweitzer said Ardis's claim misleads. "There are interactions between nicotine and thyroid hormones that have been clearly demonstrated in animal models," Sweitzer said (archived here and here). "But I am not aware of any evidence that would suggest nicotine can be used as a treatment in itself." Rexford Ahima, director of the division of endocrinology, diabetes and metabolism at Johns Hopkins University, agreed (archived here). "Nicotine does not cure hypothyroidism," Ahima told AFP in a July 15 email. "Nicotine use, especially through smoking, is linked to worsening of autoimmune hyperthyroidism." AFP has debunked other health misinformation here.
Yahoo
28-02-2025
- Health
- Yahoo
Experts advise against black seed oil as bird flu treatment
"This black seed oil is so potent -- 90 percent killing all avian influenza virus, called H5N1, known as bird flu," claims Bryan Ardis in a February 3 Instagram reel. Different versions of claims touting black seed oil spread on Facebook, Instagram and X, many of them referencing Ardis, who has an online show discussing health topics. AFP has previously fact-checked Ardis for spreading misinformation about cancer treatments. The clip of Ardis discussing black seed oil comes from a video outlining the supposed benefits of a product he sells on his website that contains the substance. The studies linked under Ardis's "bio-defense" product point to potential benefits of black seed oil in treating various conditions (archived here, here and here), but experts told AFP more research needs to be done before the herbal formula could be proven as a treatment for bird flu in humans. Over the past year, doctors and the poultry industry have been tracking outbreaks of bird flu which have led to American egg shortages and in some cases spread to dairy cattle. Dean Blumberg, chief of the pediatric infectious diseases division at University of California, Davis Health (archived here), told AFP in a February 24 interview that people who work with animals -- especially who come in contact with liquid secretions from birds -- are currently the most at risk from avian flu. Black seed oil, derived from the Nigella sativa plant found in Asia and elsewhere, is often touted across the internet as an immune booster and general health treatment (archived here) but Blumberg said that even though there are some promising cases and small studies (archived here and here) he would not recommend the supplement to a patient to protect against or treat bird flu. "You really want large studies that really prove that something works before you rely on it," Blumberg said. "If I had bird flu, there's no way I would take something unproven like this." Blumberg favored double-blind, clinical trials, which he said had not yet been performed for black seed oil as a treatment for bird flu and other diseases. AFP was able to find a study of a small sample of patients in Saudi Arabia labelled as a randomized, clinical trial which assessed black seed oil for general health and found "promising" results (archived here). To prevent bird flu, Blumberg recommended personal protective equipment (PPE) for people working with animals to lower the risk of exposure to contaminated fluids. He also said that while there were human cases of bird flu with unknown origin, most circulating strains of the virus do not appear to typically spread between people. "It hasn't evolved yet into an efficiently transmitted human-to-human pathogen," he said. According to the US Centers for Disease Control, human vaccination against bird flu is not recommended at this time (archived here). While Health Canada says there is a low public risk for the pathogen, it did acquire 500,000 doses of GSK human bird flu vaccines (archived here). Blumberg explained that human cases of bird flu can be treated with antiviral medications such as Tamiflu and supportive care including supplemental oxygen if a patient is having trouble breathing (archived here and here). David Cennimo, an associate professor of medicine and pediatrics at the Rutgers New Jersey Medical School (archived here), agreed with Blumberg that even if there is some potential for black seed oil to treat bird flu and other diseases, clear and widely-accepted evidence is lacking. "Some authorities on alternative medicine suggest robust studies need to be done," Cennimo said in a February 25 email. "I tend to favor that approach." Cennimo said he had not found any significant toxicities from black seed oil, but still recommended users check for adverse interactions between supplements and prescription medication. He also said common antivirals used against influenza had already proved effective against current strains of avian influenza and that he would prefer to treat someone with medication that has been evaluated in "well-designed studies." "I caution individuals not to pass up a proven benefit for an uncertain claim about black seed," he said. Robert Hopkins, medical director of the National Foundation for Infectious Disease in the United States (archived here), also discouraged the use of black seed oil for bird flu and recommended limiting exposure to animal fluids and consultation with a health professional for guidance on testing and treatment. "Scientific studies do not support the use of black seed oil as a treatment for bird flu," Hopkins said in a February 25 email. "However, antiviral flu drugs like oseltamivir are effective in treating bird flu, and new vaccines are being developed," (archived here). Health Canada told AFP that black seed oil is a regulated Natural Health Product (NHP) in Canada and that the agency had authorized two formulations which used it in combination with other substances for general health maintenance products (archived here and here). However, it does not recognize black seed oil as a reliable treatment for bird flu. "Health Canada has seen no evidence to suggest black seed oil works to cure diseases like bird flu, and the department has neither received nor authorised the use of any NHP for treating bird flu in humans," said Mark Johnson, a Health Canada spokesman, in February 25 email. Johnson said selling or advertising unauthorized health products in Canada is illegal. The US Food and Drug Administration has issued at least two warnings to sellers of products with black seed oil over unproven claims that their stock cured, prevented or treated disease (archived here and here). Read more AFP's reporting on health misinformation here.


AFP
28-02-2025
- Health
- AFP
Experts advise against black seed oil as bird flu treatment
"This black seed oil is so potent -- 90 percent killing all avian influenza virus, called H5N1, known as bird flu," claims Bryan Ardis in a February 3 Instagram reel. Different versions of claims touting black seed oil spread on Facebook, Instagram and X, many of them referencing Ardis, who has an online show discussing health topics. AFP has previously fact-checked Ardis for spreading misinformation about Image Screenshot of an Instagram post taken February 28, 2025 The clip of Ardis discussing black seed oil comes from a video outlining the supposed benefits of a product he sells on his website that contains the su The studies linked under Ardis's "bio-defense" to potential benefits of black seed oil in treating various conditions (archived here, here and here), but experts told AFP more research needs to be done before the herbal formula could be proven as a treatment for bird flu in humans. Over the past year, doctors and the poultry industry have been tracking outbreaks of bird flu which have led to American egg shortages and in some cases spread to dairy cattle. Dean Blumberg, chief of the pediatric infectious diseases division at University of California, Davis Health (archived here), told AFP in a February 24 interview people who work with animals -- especially who come in contact with liquid secretions from birds -- are currently the most at risk from avian flu. Black seed oil, is often touted across the internet as an immune booster and general health treatment (archived here) but Blumberg said that even though there are some promising cases and small studies (archived here and here) he would not recommend the supplement to a patient to protect against or treat bird flu. "You really want large studies that really prove that something works before you rely on it," Blumberg said. "If I had bird flu, there's no way I would take something unproven like this." Blumberg favored double-blind, clinical trials, which he said had not yet been performed for black seed oil as a treatment for bird flu and other diseases. AFP was able to find a study of a labelled as a randomized, clinical trial which assessed black seed oil for general health and found "promising" results (archived here). Prioritizing 'proven benefits' To prevent bird flu, Blumberg recommended personal protective equipment (PPE) for people working with animals to lower the risk of exposure to contaminated fluids. He also said that while there were human cases of bird flu with unknown origin, most circulating strains of the virus do not appear to typically spread between people. "It hasn't evolved yet into an efficiently transmitted human-to-human pathogen," he said. According to the US Centers for Disease Control, human vaccination against bird flu is not recommended at this time (archived here). While Health Canada says there is a low public risk for the pathogen, it did acquire 500,000 doses of GSK human bird flu vaccines (archived here). Blumberg explained that human cases of bird flu can be treated with antiviral medications such as Tamiflu and supportive care including supplemental oxygen if a patient is having trouble breathing (archived here and here). David Cennimo, an associate professor of medicine and pediatrics at the Rutgers New Jersey Medical School (archived here), agreed with Blumberg that even if there is some potential for black seed oil to treat bird flu and other diseases, clear and widely-accepted evidence is lacking. "Some authorities on alternative medicine suggest robust studies need to be done," Cennimo said in a February 25 email. "I tend to favor that approach." Cennimo said he had not found any significant toxicities from black seed oil, but still recommended users check for adverse interactions between supplements and prescription medication. He also said common antivirals used against influenza had already proved effective against current strains of avian influenza and that he would prefer to treat someone with medication that has been evaluated in "well-designed studies." "I caution individuals not to pass up a proven benefit for an uncertain claim about black seed," he said. Robert Hopkins, medical director of the National Foundation for Infectious Disease in the United States (archived here), also discouraged the use of black seed oil for bird flu and recommended limiting exposure to animal fluids and consultation with a health professional for guidance on testing and treatment. "Scientific studies do not support the use of black seed oil as a treatment for bird flu," Hopkins said in a February 25 email. "However, antiviral flu drugs like oseltamivir are effective in treating bird flu, and new vaccines are being developed," (archived here). Substance regulations Health Canada told AFP that black seed oil is a regulated Natural Health Product (NHP) in Canada and that the agency had authorized two formulations which used it in combination with other substances for general health maintenance products (archived here and here). However, it does not recognize black seed oil as a reliable treatment for bird flu. "Health Canada has seen no evidence to suggest black seed oil works to cure diseases like bird flu, and the department has neither received nor authorised the use of any NHP for treating bird flu in humans," said Mark Johnson, a Health Canada spokesman, in February 25 email. Johnson said selling or advertising unauthorized health products in Canada is illegal. The US Food and Drug Administration has issued at least two warnings to sellers of products with black seed oil over unproven claims that their stock cured, prevented or treated disease (archived here and here). more AFP's reporting on health misinformation here.