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Yahoo
5 days ago
- Entertainment
- Yahoo
Was Destination X Too Confusing to Follow? Grade the NBC Competition Hosted by Jeffrey Dean Morgan
Though he's fought off zombies for years, Jeffrey Dean Morgan is now facing something even more frightening: a group of globe-trotting reality-TV contestants on NBC's Destination X. But did the series miss the mark? Let's recap. Tuesday's premiere takes us on a winding journey as the Walking Dead vet turns Europe into a real-life game board. Here's how it works: Each week, players will traverse the continent in a blacked-out bus with the goal of figuring out where they are. After competing in challenges at unique tourist attractions, contestants will head to the Map Room where they must guess their exact current location. The player with the guess farthest away from the bus' actual destination has to leave the game, and loses the chance to win $250,000. More from TVLine TWD: Dead City's Jeffrey Dean Morgan Does His Damnedest to Plug a Massive Plot Hole TWD: Dead City Stars Tease Season 2's Higher Stakes, Surprising Moral and… What?!? 'I Won't Be in Season 3' The Handmaid's Tale Brings Back [Spoiler] in Powerful Series Finale - How Did June's Story End? But for a casual viewer, the game can be confusing. To start, you'll see contestants donning high-tech goggles from time to time, but they aren't virtual reality headsets. The eyewear functions only as a fancy blindfold — there is no VR component in this game. Next, hints are not necessarily directly tied to the destination. For example, Episode 1 grants two contestants an exclusive clue: access to an outdoor theater. The players stand in front of the ruins, which viewers learn are the ruins of Volterra in Italy. But this place is not Destination X. We're told it sits 200 miles away from the actual location — which remains unknown to viewers. The only hint the clue offers is it looks Italian, but that offers no help in deducing the city — especially since the ruins aren't even located in Destination X anyway. The bus continues on a journey to its official location, stopping for a team challenge, where players solve riddles to collect hidden coins offering secret clues. Morgan says the challenge takes place in Orvieto and features nods to the city's cathedral, rich olive oil and St. Patrick's well — all of which are meant to serve as additional clues for Destination X. The group didn't pick up on the hints, but even if they had, how does identifying Orvieto help anyone deduce where the final location will be? Viewers are told Orvieto is still 90 miles away from Destination X. In the end, the team that loses the challenge must enter the Map Room, risking elimination. After all the guesses are in, it's Big Brother vet Josh Martinez who places his guess farthest from the location, placing his 'X' on Milan. On his way out, we finally learn this week's official Destination X: Rome. (Though the group had spent no actual time there.) Apparently, the prior challenge's coins had featured clues hinting at the city's gladiators and the Vatican's Swiss Guard. What did you think of s debut? Will you stay along for the ride, or are you ending your trip early? Vote in the polls below and hit the comments with your thoughts! Best of TVLine Mrs. Maisel Flash-Forward List: All of Season 5's Futuristic Easter Eggs Yellowjackets Recap: The Morning After Yellowjackets Recap: The First Supper
Time of India
26-05-2025
- Health
- Time of India
Pills, promotions and a dose of doubt: Influencers, VC money fuel India's booming supplements market
Live Events A decade ago, India's health supplements mostly meant vitamin C, iron and B12 tablets purchased at pharmacies after consulting a doctor. Fast forward to 2025, and a whole new market has emerged—gummies to enhance your hair health, powders to boost collagen, liquid for gut, pills for women's perimenopause hormonal imbalance, magnesium tablets for better sleep, testosterone boosters, capsules with calming properties and vegan versions of all supplement wave in the country was sparked by increased health awareness after the Covid-19 pandemic and powered by social media influencer marketing and a rush of venture capital (VC), according to industry executives and products are being sold directly to consumers on ecommerce websites as well as quick-commerce apps, spawning a fast-growing segment within the health sector. But as gummies and pills become lifestyle staples, the line between wellness and pseudoscience is blurring. Most items are sold over the counter—with no prescription, no pharmacist and often no clarity on whether they actually result? A shelf full of products that look similar, promise big results and raise a critical question—how much of it is science, and how much social media hype?India's nutritional supplement industry, pegged at $47.92 billion in 2024, is projected to expand to $68.43 billion by 2030, at a compound annual growth rate of 8.1%, according to market research firm Research and Markets. The growth story has attracted both founders and venture capitalists. 'Just after the Covid-19 pandemic, the evolution of these nutra products happened with immunity-building items. After seeing good acceptance from the audience and more usage of digital platforms (ecommerce and quick-commerce) to buy such products, brands started experimenting with their offerings,' said Renu Bisht, founder of Commercify360, a Gurgaon-based brand consulting funding numbers back this up. According to data firm Venture Intelligence, the sector raised more than $500 million between 2020 and May 2025. The latest in the line is Mumbai-based The Good Bug, a gut health startup that raised about $12 million in a round led by Susquehanna Asia Venture Capital, with Fireside Ventures Khaitan, principal at Fireside Ventures, emphasised the sharpening focus on science and research, along with innovation, in delivery formats. 'As themes like women's health, longevity and bone health evolve, we are looking to double down on startups operating at the intersection of unmet consumer needs and science-led innovation,' he health professionals are beginning to worry that the focus is shifting from effectiveness to aesthetics. 'The wellness sector is booming in India, which is why a lot of companies are getting a lot of VC funding early on. They use a lot of that funding to basically not work so much on the formulation but more on the marketability of a product,' said Poorvi Bhat Khandige, a Bengaluru-based naturopathic physician and nutritionist.'Health supplement brands are heavily reaching out to influencers because the concept is fairly new in India,' said Commercify 360's Bisht. 'Brands are partnering with health influencers, doctors and fitness trainers for marketing in order to build the audience's trust. Some brands are spending 15–30% of their budget on influencer marketing.'For example, nutrition brand Plix partners with Gen Z creators to reach urban, health-aware label Kapiva, from Kolkata-based Baidyanath, works with regional wellness influencers, while nutrition brand Fast&Up aligns with athletes and fitness content creators. 'We are trying to reach our target audience and continuously build awareness at the right frequency with them,' said Keshav Biyani, founder of gut health-focused brand The Good Unilever-backed Wellbeing Nutrition , a direct-to-consumer nutraceutical player, said 20-25% of its expenses are allocated to companies are ramping up their marketing budgets to build awareness by partnering with doctors and the marketing-first approach leads to many consumers buying the products without understanding them, and sometimes overusing them, leaving experts and nutritionists worried.'We've seen almost 200% growth month-on-month where protein is concerned, which is good and bad,' said Avnish Chhabria, founder of Wellbeing Nutrition. 'It's good, because everyone's gotten the sense and understanding of what they need to take. It's bad, because even people who are eating enough protein in a day are now overconsuming it, which could eventually lead to kidney problems.'The lack of guidance regarding the usage of such products poses a real risk. In some cases, certain ingredients require specific lifestyle choices to be instance, a Jaipur-based consumer used a popular nutrition brand's metabolically lean powder for more than a year before eventually stopping, after realising that some ingredients in the product required lifestyle adjustments. 'The product has EGCG and ALA (epigallocatechin gallate and alpha-lipoic acid are ingredients typically used in weight loss products), both of which can cause issues if you're not active,' the person said on condition of some products may fall short of their promises. Hair gummies, for example, are marketed with the promise of improving hair health and making it stronger and shinier. However, according to Khandige, a nutritionist, many of these products don't contain a sufficient therapeutic dose to be truly as the market expands, several leading brands are grappling with challenges tied to regulatory scrutiny, supply chain issues and shifting consumer expectations. GNC , a supplement retailer in the US—where the supplements market is projected to exceed $70 billion by 2031, from around $43 billion in 2022, according to data and business intelligence platform Statista—has faced multiple legal battles over product quality. Elysium Health, known for its anti-aging supplements, has drawn criticism from scientists, who have questioned the efficacy of its claims. However, the risk of such products reaching Indian consumers is heightened by the rise of fast and frictionless delivery channels such as quick-commerce supplement products in India fall under the purview of the Food Safety and Standards Authority of India, and not the drug regulator. That means weaker scrutiny and lighter penalties despite brands making bold claims like 'improves liver health' or 'reverses aging'.Health experts have long called for stringent oversight. Recently, an inter-ministerial committee headed by former health secretary Apurva Chandra recommended that any supplement claiming to treat or mitigate a disease should be classified as a drug. That would bring such products under the Central Drugs Standard Control Organisation and subject them to stricter regulation. Experts agree that until there is better education, regulation and transparency, consumers will largely have to navigate this booming market on their own—one Instagram ad at a time.
CNBC
25-05-2025
- Business
- CNBC
Warren Buffett will retire as a CEO—but still plans to go into the office: 'I'm not going to sit at home and watch soap operas'
Warren Buffett is stepping down as CEO of Berkshire Hathaway at the end of this year — but he may not actually stop working. Instead of sitting at home, the 94-year-old plans to spend his post-CEO days regularly going into Berkshire Hathaway's Omaha, Nebraska, headquarters to keep contributing his investment ideas and decision-making skills, he told the Wall Street Journal on May 14. "I'm not going to sit at home and watch soap operas," said Buffett. "My interests are still the same."' Before Berkshire Hathaway's most recent annual shareholders' meeting, on May 3, Buffett hadn't publicly announced plans to retire. Internally, he'd decided to "remain CEO as long as I thought I was more useful than anybody else ... And it surprised me, you know, how long it went," he said. In May 2021, Buffett named his eventual successor as Greg Abel, the company's vice-chairman of non-insurance operations. Recently, he compared his energy levels to Abel's, and decided that his successor had surpassed him in terms of ability to be the company's CEO, he told the Journal. "The difference in energy level and just how much [Abel] could accomplish in a 10-hour day compared to what I could accomplish in a 10-hour day—the difference became more and more dramatic," said Buffett. "He just was so much more effective at getting things done, making changes in management where they were needed, helping people that needed help someplace, but just all kinds of ways."But even as Buffett occasionally loses his balance or has trouble recalling a person's name, as the Journal reported, his ability to make smart decisions in turbulent markets hasn't faltered, he said. "I will be useful here if there's a panic in the market because I don't get fearful when things go down in price or everybody else gets scared," said Buffett. "And that really isn't a function of age." Buffett's quasi-retirement isn't unprecedented. A small but quickly growing number Americans are choosing to work past the age of 75, according to the Bureau of Labor Statistics. Continuing to work seems like an especially prevalent mindset among business leaders, from Microsoft co-founder Bill Gates to Costco co-founder Jim Sinegal. "My friend Warren Buffett still comes into the office six days a week," Gates, 69, told CNBC Make It in September 2024. "So, I hope my health allows me to be like Warren." Sinegal, 89, stepped down from his own CEO role in 2012 — and still goes into the office some Tuesdays, The Wall Street Journal reported on April 16. He always viewed running Costco as more of a hobby than a job, and wanted to continue that sense of enjoyment even after leaving the CEO role, he told the Journal. Sinegal's sentiment echoes a notable piece of advice that Buffett wrote in his 2022 letter to Berkshire Hathaway shareholders: Job seekers should look for a role that "they would select, if they had no need for money." The mindset is good for your career, and helps you live a longer, happier life, Buffett said at Berkshire Hathaway's most recent shareholders' meeting. "I think a happy person lives longer than somebody that's doing things they don't really admire that much in life," said Buffett. ,
Yahoo
20-05-2025
- Health
- Yahoo
Chronic Total Occlusion Market Size to Surpass USD 42.21 Billion by 2031, Increasing Prevalence of Cardiovascular Diseases Fuels
The report runs an in-depth analysis of market trends, key players, and future opportunities. The chronic total occlusion market comprises a vast array of products that are expected to register growth in the coming years. US & Canada, May 20, 2025 (GLOBE NEWSWIRE) -- According to a new comprehensive report from The Insight Partners, the chronic total occlusion market is observing significant growth owing to the increasing prevalence of cardiovascular diseases and strategic initiatives by market players. The global Chronic Total Occlusion (CTO) devices market is experiencing significant growth, driven by the rising prevalence of cardiovascular diseases and advancements in minimally invasive procedures. Top key players include Medtronic, Boston Scientific Corporation, Terumo, Abbott, and Philips. North America leads the market, while the Asia-Pacific region is expected to witness the fastest growth due to increasing healthcare investments and an expanding patient explore the valuable insights in the Chronic Total Occlusion Market report, you can easily download a sample PDF of the report - Overview of Report Findings 1. Market Growth: The chronic total occlusion market is expected to reach US$ 42.21 billion by 2031 from US$ 24.46 billion in 2021; it is anticipated to register a CAGR of 8.2% from 2025 to 2031. Chronic total occlusion is a condition in which the coronary artery blockage due to atherosclerosis and the restricted blood flow to the heart can lead to chest pain and heart attacks, leading to various other complications. The increasing prevalence of cardiovascular disorders owing to the increasing aging population and changing lifestyle, along with surging initiatives by market players, contribute to the market growth. 2. Rising Prevalence of Cardiovascular Diseases (CVDs): The rise in CVD patients has increased the demand for advanced treatments such as chronic total occlusions (CTO). This demand has led to a significant increase in the use of percutaneous coronary intervention (PCI) procedures, particularly among aging populations. According to the World Health Organization (WHO), ~30 million people suffer from strokes every year. As per the American Heart Association, there were more than 130 million people (i.e., approximately 45% of the total population) are expected to have some form of CVD by the end of 2035. In Europe, among patients with atrial fibrillation (AF), the most common arrhythmia consumes 0.28-2.6% of healthcare spending among European countries. They are estimated to have five times the risk of having a stroke compared to those who are not affected and 20-30% of total stroke cases in Europe. The number of people aged 65 and above having AF in the EU is expected to increase from 7.6 million in 2016 to approximately 14.4 million by 2060. It is anticipated that the incidence of AF is expected to increase from 7.8% in 2016 to 9.5% by 2060. According to the "Beyond the Burden: The Impact of Atrial Fibrillation in Asia Pacific," Study Published by Biosense Webster, in the Asia Pacific region, the number of individuals suffering from AF is expected to increase from 16 million in 2019 to ~72 million by 2050. The WHO estimates 17.9 million deaths annually from CVDs, which amount to 32 % of total fatalities worldwide. Major risk factors comprise family history, age, ethnicity, lifestyle habits, smoking (aggravating the odds by 25%), poor diet, inactivity, obesity, hypertension, high cholesterol, diabetes, and alcohol consumption. 3. Strategic Initiatives by Companies: Market players focusing on product approvals, collaborations, mergers, partnerships, acquisitions, and product launches, which are expected to help in sales growth, geographic expansion, and improvement in their capacities to cater to a larger customer base. Among the strategic initiatives taken by key players operating in the market are: In June 2024, MiccoRort RotaRace's Intravascular Piezoelectric Guidewire System gained NMPA approval for entry into the special review procedures for innovative medical devices. This system was co-developed by a team led by Academician Junbo Ge from Zhongshan Hospital, Fudan University. In February 2024, BIOTRONIK introduced the Micro Rx catheter, a rapid exchange microcatheter developed to enhance guidewire support during PCI. The Micro Rx catheter is the fourth IMDS product that BIOTRONIK has introduced to the US market, contributing to a strong portfolio of devices, which include the NHancer Rx, JrailT, and ReCross catheters. In October 2022, the FDA approved NovaCross line of microcatheters (NovaCross BTK for below-the-knee treatment along with NovaCross Xtreme and NovaCrass CTO for chronic total occlusion treatment) was among the assets that Miccobot Medical Inc. purchased from Nitiloon Ltd. The NovaCrass devices are designed to make it easier to implant conventional and steerable guidewires intraluminally beyond stenotic lesions, including chronic complete occlusions, prior to percutaneous transluminal coronary angioplasty or stent intervention. In February 2022, Teleflex Incorporated received FDA approval for the expanded indications of its specialty catheters and coronary guidewires, specifically for use in chronic total occlusion percutaneous coronary interventions (CTO PCI). 4. Geographical Insights: In 2023, Asia Pacific led the market with a substantial revenue share, followed by North America and Europe. Asia Pacific is expected to register the highest CAGR during the forecast period. Stay Updated on The Latest Chronic Total Occlusion Market Trends: Market Segmentation Based on equipment, the chronic total occlusion market is segmented into guide wires, microcatheters, crossing devices, re-entry devices, and others. The guide wires segment held the largest share of the market in 2023. By end user, the market is segmented into hospitals, ambulatory care centers, and others. The hospitals segment dominated the market in 2023. The chronic total occlusion market is segmented into five major regions: North America, Europe, APAC, Middle East & Africa, and South & Central America. Competitive Strategy and Development Key Players: Major companies operating in the chronic total occlusion market include Asahi Intecc Co Ltd, Cordis Corp, Integer Holdings Corp, Boston Scientific Corp, Koninklijke Philips NV, Becton Dickinson and Co, SoundBite Medical Solutions, Medtronic Plc, Terumo Corp, and Abbott Laboratories. Trending Topics: Chronic Total Occlusion Devices, Cardiovascular Devices, Coronary Artery Disease, Atherosclerotic Cardiovascular Disease, And Heart DiseasePurchase Premium Copy of Global Chronic Total Occlusion Market Size and Growth Report (2025-2031) at: Conclusion The demand for chronic total occlusion (CTO) is driven by the surging prevalence of coronary artery disease, technological advancements in medical technology, and increasing demand for minimally invasive procedures. CTO, characterized by a complete blockage of coronary arteries, is a significant treatment, driving innovation in diagnostic tools, interventional devices, and therapeutic options. The surging aging population, increasing rates of hypertension, diabetes, and smoking, along with increasing adoption of catheter-based interventions over traditional surgery, contribute to the market growth. Technological advancements, such as improved coronary angioplasty techniques, the development of specialized guidewires, and increasing use of drug-eluting stents, are contributing to better outcomes and reduced risk of restenosis. Additionally, the expansion of hybrid treatment approaches combining surgery and interventional techniques is gaining popularity. The report from The Insight Partners, therefore, provides several stakeholders—including chronic total occlusion device manufacturers, chronic total occlusion device distributors, and others—with valuable insights into how to navigate this evolving market landscape and unlock new to Us Directly: Related Reports: About Us: The Insight Partners is a one stop industry research provider of actionable intelligence. We help our clients in getting solutions to their research requirements through our syndicated and consulting research services. We specialize in industries such as Semiconductor and Electronics, Aerospace and Defense, Automotive and Transportation, Biotechnology, Healthcare IT, Manufacturing and Construction, Medical Device, Technology, Media and Telecommunications, Chemicals and Materials. Contact Us: If you have any queries about this report or if you would like further information, please contact us: Contact Person: Ankit Mathur E-mail: Phone: +1-646-491-9876 PRESS RELEASE - in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
USA Today
12-05-2025
- Entertainment
- USA Today
James Patterson says latest release may be 'the most important book I've done by far'
James Patterson says latest release may be 'the most important book I've done by far' Show Caption Hide Caption For the love of books | The Excerpt Podcast Best-selling author James Patterson and viral librarian Mychal Threets talk about their shared love of books. James Patterson doesn't need any more money. He's the first to admit it. "I really don't," he says. "That's not why I wrote this book." The new book in question from the prolific gagillion-selling author of thrillers (OK, for the record, it's 319 books written and 450 million copies sold worldwide) is in fact not only a labor of love, but also a love letter to fellow fathers. "The #1 Dad Book: Be the Best Dad You Can Be – In 1 Hour!," out May 12 ($25, Little, Brown and Company), sounds a bit like it got its title from a late night infomercial. But there is some truth in that bold advertising. The slim volume actually can be read in about 60 minutes (that's what the "1 Hour" in the title refers to) and features short chapters with titles such as "Be Consistent, Consistently," a litany of dad-experience quotes from friends ("Sometimes you have to let them sink to learn how to swim"), and a breezy voice that eschews hectoring for cajoling ("You've probably figured out that not everyone is in love with the sound of your voice," Patterson writes. "But guess what? Your baby is.") For Patterson, proud father with wife Susan to son, Jack, 27, the book was a way to help guys who "just don't know how to talk about such things with other guys, but they need someone to talk to and I just figured I'd offer some advice, that's all." For James Patterson, being a father meant being more emotive than his own had been The author's own father might have benefited from this book, Patterson says. "The only time I got a hug from my father was on his death bed," Patterson tells USA TODAY. "That was just the era. He grew up in a poor house, he didn't have a father, didn't know how to be a father. He was a good guy in his own way, but you talk about distance. Anyway, that's still an issue for some dads today; dads who can't say I love you and don't hug." "The #1 Dad Book" tackles hugs, of course. In the chapter "You're Not A Hugger? You Will Be in a Minute," Patterson relates the short story of visiting a friend with two hulking football player sons. When the kids started to head out the door, their father called them back saying, "Where do you think you two are going?" And he gave them hugs. "And that's when that routine became a part of my life, and Jack's, because every night he got a hug," says Patterson, smiling. "Jack's a good kid, he calls us every day." Likely many fathers and fathers-to-be will recognize some familiar themes in the book. A few that Patterson highlights include being truly present (don't talk to your kid while you, or they, are half-looking at a phone) and growing up. Fast. In the chapter called "Tattoo This Behind Your Eyeballs," Patterson is blunt with dads. "We're pals now, right? So you can take it when I give you some bad news," he writes. "It's time to grow ... No more BASE jumping, no more treks to Burning Man, no more swimming with sharks," no more beer league softball tournaments or all-day golf outings (this from Patterson, an avid golfer). "It's just hugely important, because you're taking on a big new responsibility and you have to step up," Patterson says. "And hopefully you're cool with it." Dads, make sure you're talking with friends about fatherhood along with sports, says James Patterson Patterson also encourages men to seek out male friends who are willing to talk about dad issues, instead of "just what's going on with the local sports team." He notes that these days, "it's often women that are the primary bread winners, and some guys are just lost as a result, they don't know what their role is, and sometimes there's a lot of anger which is not useful for anyone." So is there any advice he's doling out in "The #1 Dad Book" that he wishes he'd gotten years ago upon entering his first fatherhood years? Patterson mulls a bit. Turns out, for him it was paying closer attention to Jack. "I was always home and around for him, but I could have been more present," he says, noting that while he was writing at home he often was lost in his projects. "I was there, but I wasn't ... I could have done more trips I didn't want to do, like going to the Galapagos, things like that. I'm not big on it, but Jack, he would have liked that." With this book, which Patterson says cryptically he "won't make money on, they way I've structured it," he's hoping that perhaps wives and daughters will pick one up for "husbands and fathers and maybe those two knuckle-headed brothers." Patterson leans back in his office chair. "This honestly could be the most important book I've done by far," he says. "It doesn't matter if someone reads an Alex Cross book. I mean, of course it's nice, but you know." Then almost as a challenge to dads everywhere, he adds: "It's one hour, dude. One hour ... you can't improve your golf game in an hour but here, maybe you can learn a few things in that short amount of time that will make you a little bit better father, or partner. And that's a good thing."
