Latest news with #Charpentier
Hindustan Times
25-05-2025
- Automotive
- Hindustan Times
Godzilla will be back, promises Nissan as a new GT-R is on the card
The new Nissan GR-R is on the card and it claims to come reinventing the notion of a sportscar. The new Nissan GR-R is on the card and it claims to come reinventing the notion of a sportscar. Check Offers Nissan GT-R may not be currently in business, but that doesn't diminish the consumer attention towards this car. And keeping that in mind, Nissan is working on a new GT-R. The Japanese car manufacturer that has been sailing through troubled waters has confirmed that a new GT-R is in development. Nissan GT-R, which is popularly known as Godzilla as one of the insanely powerful sportscar is gearing up for a return. Auto Express has quoted Nissan's VP of Product Marketing Strategy, Arnaud Charpentier, saying that the GT-R will be back, without a doubt. This comment comes at a time when Nissan is undertaking a massive cost-cutting agenda after losing billions in recent years due to sales slumping short of investments. Also Read : Upcoming cars in India While the car manufacturer's new product strategy centres on the usual body styles like SUVs and crossovers, owing to the high demand for such models, the next-generation GT-R is also in development. 'There are people working on this. When, how, honestly, this we don't know. But today, we don't just need to make a sports car, but to do one with a powertrain that we foresee [working] in the coming years. If it is electric or electrified, it needs to remain a sports car. [But] if you end up with the same performance as an EV SUV, this is an issue," Charpentier said. He also said that upon arrival, the new Nissa GT-R will reinvent the notion of a sports car. It's been about a year and a half since the company hinted that the next GT-R might come as a fully electric car. The Hyper Force concept, an ultra-angular supercar promising about 1,341 bhp peak power, was described as a tangible dream to achieve by the end of the decade. Also, it previewed what the new Nissan GT-R may look like. While Nissan is still enthusiastic about a new GT-R, there are a host of challenges ahead of this project as well. The struggling Japanese carmaker has bigger priorities and is unlikely to favour a GT-R soon at the expense of a high-volume SUV. Surely, a new supercar would boost Nissan's image and draw more people into the showrooms, but in reality, the OEM may be more inclined to play it safe with volume-driven vehicles like SUVs and crossovers. Check out Upcoming Cars in India 2024, Best SUVs in India. First Published Date: 25 May 2025, 13:29 PM IST
CNBC
06-05-2025
- Health
- CNBC
CRISPR-based gene editing revolutionized medicine—what's next for the firm that helped develop it?
CRISPR-Cas 9 is a gene-editing tool that made it possible to rewrite any organism's genetic code and tackle genetic diseases more effectively. Known as genetic scissors, CRISPR identifies a DNA sequence that is cut by an enzyme called Cas 9. It then changes or replaces that sequence with a different section of DNA. For this discovery, co-inventors Emmanuelle Charpentier and Jennifer Doudna received the Nobel Prize in Chemistry in 2020. "By our interest in the lab to find new molecules that could have a role in in the bacterium streptococcus pardonus , we came across a very neat mechanism that allows to really recognize the virus that infects the bacterium in a very, very specific minor at the level of the genome of the virus. And we exploited this natural mechanism to develop the CRISPR-Cas9 technology," Emmanuelle Charpentier said in an interview with CNBC's The Edge. In 2013, Charpentier co-founded CRISPR Therapeutics to fulfil her lifelong goal of finding cures for diseases. A decade later, the company and its partner Vertex Pharmaceuticals developed CASGEVY, a therapy to treat blood disorders beta thalassemia and sickle cell disease. "With CASGEVY, we're taking the bone marrow cells from the patient, making the edit for that particular patient and we're putting it back into the patient, and it reconstitutes the hematopoietic system of the patient. We're making a drug just for you," CRISPR Therapeutics' CEO Samarth Kulkarni told The Edge. CASGEVY is a one-time therapy that costs $2.2 million per patient and can be administrated on patients 12 years of age and older. In 2023, it became the first CRISPR-based gene editing therapy to be approved by the Federal Drug Administration. CRISPR Therapeutics currently has seven clinical and ten pre-clinical programs across oncology, autoimmune cardiovascular disease and diabetes, and is investigating next generation editing modalities. Watch the video above for the full interview with Professor Charpentier from Berlin, Germany, and a tour of CRISPR Therapeutics' facilities in Boston, Massachusetts.
IOL News
28-04-2025
- Business
- IOL News
Global shipping navigates Trump tariffs uncertainty
In the long run, shipping companies expect a decline in freight rates -- as happened in 2018-2019 during Trump's first presidential term. Shifting trade announcements have led to unprecedented volatility in the global shipping industry in recent weeks, with industry players having to constantly adapt to new US tariffs. Cargo ships put to sea half empty, fluctuating freight rates and possible shipping route changes are some of the recent adjustments industry specialists have noted. The global economy has been riding a rollercoaster since US President Donald Trump returned to the White House in January and kicked off a tariff offensive. Trump's recent walk-back, announcing a 90-day pause on some previously announced levies -- with the exception of those targeting China -- has once again upset the balance. "In the three weeks leading up to the announcement, we saw a slowdown in trade and many ships were only 50% full on the transatlantic and transpacific trades to the United States," said Alexandre Charpentier, transport specialist at consulting firm Roland Berger. During that time, sea freight rates fell and many companies held on to their stocks as a precaution. "As of last week, we've had the opposite effect," Charpentier said. "People want to ship as much as possible to the United States, they're destocking and there has been a rush for space." And prices have started to rise again. Adding to the headwinds facing shipping are new US port fees for Chinese-built and -operated ships, unveiled by Washington on Thursday and due to kick in from mid-October. Those come on top of the tariffs of up to 145% the Trump administration has introduced on a large number of Chinese imports, resulting in a top tax line as high as 245% on some products. China builds nearly half of all ships launched, ahead of South Korea and Japan. Falling freight rates In the long run, shipping companies expect a decline in freight rates -- as happened in 2018-2019 during Trump's first presidential term. Back then liners "experienced an oversupply of shipping capacity, decreased shipping rates, increased operational costs and ultimately, a reduction in revenue," said Sandy Gosling, specialist in transport and logistics at consulting firm McKinsey. Tariffs then were lower than those announced by Trump this year. "It's difficult to see into the future but what seems most likely to us is a slowing of certain routes in favour of other countries in Southeast Asia or India," said Charpentier. Anne-Sophie Fribourg, vice president of ocean procurement at British freight forwarder Zencargo, said she expected the China-US route would become unprofitable. If this were to happen, she said, "shipowners will readjust their rotations. In other words, they will turn away from traditional routes to new ones, such as Latin America, where demand has been growing for some time now." For the time being, major international companies such as MSC, CMA CGM and Maersk have not made such adjustments. Adjusting routes German container shipping firm Hapag-Lloyd said it was not noticing any changes on the Atlantic. It however saw a "massive decline in China", offset by "a clear increase in demand in South-East Asia". Consulting firm Boston Consulting Group said in a note sent to its clients that it expected a sharp decline in China-US trade and an increase in trade within what it called the "Global South". The World Trade Organization (WTO) warned of a potential "even sharper decline of 1.5 percent in global goods trade" in 2025, depending on Trump's tariffs policy. It said merchandise trade between China and the US could plunge by 81 percent. Gosling said tariffs are just the latest of many disruptions the shipping industry suffered in recent decades. "According to a 2020 McKinsey Global Institute report, industries have experienced material disruptions lasting a month or longer every 3.7 years on average," she said. Logistical chains were upended during the Covid-19 years, before Huthi attacks in the Red Sea drove vessels to round Africa via the Cape of Good Hope. Shipowners have developed a certain "agility to change routes," said Fribourg of Zencargo. But adjusting flows toward other destinations "will take some time", Charpentier said. AFP
The Sun
22-04-2025
- Business
- The Sun
Global shipping navigates unprecedented volatility
PARIS: Shifting trade announcements have led to unprecedented volatility in the global shipping industry in recent weeks, with industry players having to constantly adapt to new US tariffs. Cargo ships put to sea half empty, fluctuating freight rates and possible shipping route changes are some of the recent adjustments industry specialists have noted. The global economy has been riding a rollercoaster since US President Donald Trump returned to the White House in January and kicked off a tariff offensive. Trump's recent walk-back, announcing a 90-day pause on some previously announced levies – with the exception of those targeting China – has once again upset the balance. 'In the three weeks leading up to the announcement, we saw a slowdown in trade and many ships were only 50% full on the transatlantic and transpacific trades to the US,' said Alexandre Charpentier, transport specialist at consulting firm Roland Berger. During that time, sea freight rates fell and many companies held on to their stocks as a precaution. 'As of last week, we've had the opposite effect,' Charpentier said. 'People want to ship as much as possible to the US, they're destocking and there has been a rush for space.' And prices have started to rise again. Adding to the headwinds facing shipping are new US port fees for Chinese-built and -operated ships, unveiled by Washington last week and due to kick in from mid-October. Those come on top of the tariffs of up to 145% the Trump administration has introduced on a large number of Chinese imports, resulting in a top tax line as high as 245% on some products. China builds nearly half of all ships launched, ahead of South Korea and Japan. In the long run, shipping companies expect a decline in freight rates – as happened in 2018-2019 during Trump's first presidential term. Back then liners 'experienced an oversupply of shipping capacity, decreased shipping rates, increased operational costs and ultimately, a reduction in revenue,' said Sandy Gosling, specialist in transport and logistics at consulting firm McKinsey. Tariffs then were lower than those announced by Trump this year. 'It's difficult to see into the future but what seems most likely to us is a slowing of certain routes in favour of other countries in Southeast Asia or India,' said Charpentier. Anne-Sophie Fribourg, vice-president of ocean procurement at British freight forwarder Zencargo, said she expected the China-US route would become unprofitable. If this were to happen, she said, 'shipowners will readjust their rotations. In other words, they will turn away from traditional routes to new ones, such as Latin America, where demand has been growing for some time now.' For the time being, major international companies such as MSC, CMA CGM and Maersk have not made such adjustments. German container shipping firm Hapag-Lloyd said it was not noticing any changes on the Atlantic. It however saw a 'massive decline in China', offset by 'a clear increase in demand in Southeast Asia'. Consulting firm Boston Consulting Group said in a note sent to its clients that it expected a sharp decline in China-US trade and an increase in trade within what it called the 'Global South'. The World Trade Organisation (WTO) warned of a potential 'even sharper decline of 1.5% in global goods trade' in 2025, depending on Trump's tariffs policy. It said merchandise trade between China and the US could plunge by 81%. Gosling said tariffs are just the latest of many disruptions the shipping industry suffered in recent decades. 'According to a 2020 McKinsey Global Institute report, industries have experienced material disruptions lasting a month or longer every 3.7 years on average,' she said. Logistical chains were upended during the Covid-19 years, before Huthi attacks in the Red Sea drove vessels to round Africa via the Cape of Good Hope. Shipowners have developed a certain 'agility to change routes,' said Fribourg of Zencargo. But adjusting flows towards other destinations 'will take some time', Charpentier said. – AFP
CNA
22-04-2025
- Business
- CNA
Global shipping navigates Trump tariffs uncertainty
In the long run, shipping companies expect a decline in freight rates - as happened in 2018 to 2019 during Trump's first presidential term. Back then liners "experienced an oversupply of shipping capacity, decreased shipping rates, increased operational costs and ultimately, a reduction in revenue", said Sandy Gosling, specialist in transport and logistics at consulting firm McKinsey. Tariffs then were lower than those announced by Trump this year. "It's difficult to see into the future but what seems most likely to us is a slowing of certain routes in favour of other countries in Southeast Asia or India," said Charpentier. Anne-Sophie Fribourg, vice president of ocean procurement at British freight forwarder Zencargo, said she expected the China-US route would become unprofitable. If this were to happen, she said, "shipowners will readjust their rotations. In other words, they will turn away from traditional routes to new ones, such as Latin America, where demand has been growing for some time now". For the time being, major international companies such as MSC, CMA CGM and Maersk have not made such adjustments. ADJUSTING ROUTES German container shipping firm Hapag-Lloyd said it was not noticing any changes on the Atlantic. It however saw a "massive decline in China", offset by "a clear increase in demand in South-East Asia". Consulting firm Boston Consulting Group said in a note sent to its clients that it expected a sharp decline in China-US trade and an increase in trade within what it called the "Global South". The World Trade Organization (WTO) warned of a potential "even sharper decline of 1.5 per cent in global goods trade" in 2025, depending on Trump's tariffs policy. It said merchandise trade between China and the US could plunge by 81 per cent. Gosling said tariffs are just the latest of many disruptions the shipping industry suffered in recent decades. "According to a 2020 McKinsey Global Institute report, industries have experienced material disruptions lasting a month or longer every 3.7 years on average," she said. Logistical chains were upended during the COVID-19 years, before Houthi attacks in the Red Sea drove vessels to round Africa via the Cape of Good Hope. Shipowners have developed a certain "agility to change routes," said Fribourg of Zencargo. But adjusting flows toward other destinations "will take some time", Charpentier said.
